KEGG   Bison bison bison (American bison): 104998177
Entry
104998177         CDS       T08726                                 
Symbol
PAK1
Name
(RefSeq) serine/threonine-protein kinase PAK 1
  KO
K04409  p21-activated kinase 1 [EC:2.7.11.1]
Organism
bbis  Bison bison bison (American bison)
Pathway
bbis04010  MAPK signaling pathway
bbis04012  ErbB signaling pathway
bbis04014  Ras signaling pathway
bbis04024  cAMP signaling pathway
bbis04062  Chemokine signaling pathway
bbis04360  Axon guidance
bbis04392  Hippo signaling pathway - multiple species
bbis04510  Focal adhesion
bbis04625  C-type lectin receptor signaling pathway
bbis04650  Natural killer cell mediated cytotoxicity
bbis04660  T cell receptor signaling pathway
bbis04666  Fc gamma R-mediated phagocytosis
bbis04810  Regulation of actin cytoskeleton
bbis05132  Salmonella infection
bbis05170  Human immunodeficiency virus 1 infection
bbis05205  Proteoglycans in cancer
bbis05211  Renal cell carcinoma
Brite
KEGG Orthology (KO) [BR:bbis00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    104998177 (PAK1)
   04012 ErbB signaling pathway
    104998177 (PAK1)
   04014 Ras signaling pathway
    104998177 (PAK1)
   04392 Hippo signaling pathway - multiple species
    104998177 (PAK1)
   04024 cAMP signaling pathway
    104998177 (PAK1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    104998177 (PAK1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    104998177 (PAK1)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    104998177 (PAK1)
   04650 Natural killer cell mediated cytotoxicity
    104998177 (PAK1)
   04660 T cell receptor signaling pathway
    104998177 (PAK1)
   04666 Fc gamma R-mediated phagocytosis
    104998177 (PAK1)
   04062 Chemokine signaling pathway
    104998177 (PAK1)
  09158 Development and regeneration
   04360 Axon guidance
    104998177 (PAK1)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    104998177 (PAK1)
  09162 Cancer: specific types
   05211 Renal cell carcinoma
    104998177 (PAK1)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    104998177 (PAK1)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    104998177 (PAK1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:bbis01001]
    104998177 (PAK1)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:bbis04131]
    104998177 (PAK1)
   03036 Chromosome and associated proteins [BR:bbis03036]
    104998177 (PAK1)
Enzymes [BR:bbis01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     104998177 (PAK1)
Protein kinases [BR:bbis01001]
 Serine/threonine kinases: STE group
  STE20 family
   104998177 (PAK1)
Membrane trafficking [BR:bbis04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Kinases and associated proteins
    104998177 (PAK1)
 Endocytosis
  Macropinocytosis
   Kinases
    104998177 (PAK1)
Chromosome and associated proteins [BR:bbis03036]
 Eukaryotic type
  Sister chromatid separation proteins
   Aurora kinases
    Regulators of Aurora kinases
     104998177 (PAK1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr PBD ABC1 Kinase-like Pkinase_fungal APH DSHCT
Other DBs
NCBI-GeneID: 104998177
NCBI-ProteinID: XP_010851545
Ensembl: ENSBBBG00000018980
UniProt: A0A6P3IAH4
LinkDB
Position
Unknown
AA seq 544 aa
MSNNGLDIQDKPPAPPMRNTSTMIGAGSKDAGTLNHGSKPLPPNPEEKKKKDRFYRAILP
GDKTNKKKEKERPEISLPSDFEHTIHVGFDAVTGEFTGMPEQWARLLQTSNITKSEQKKN
PQAVLDVLEFYNSKKTSNSQKYMSFTDKSAEDYNSSNTLNVKAVSETPAVPPVSEDEDDD
DDGTPPPVIAPRPEHTKSVYTRSVIEPLPITPTRDVATSPISPTENNTTPPDALTRNTEK
QKKKPKMSDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQM
NLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCM
DEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKR
STMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGT
PELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQHQFLKIAKPLSSLTPLIAAAKEAT
KNNH
NT seq 1635 nt   +upstreamnt  +downstreamnt
atgtcaaataacggcctagacattcaagacaaacctccagcccctccgatgagaaatacc
agcactatgattggagctggcagcaaagacgctggaaccctaaaccacggttccaaacct
ctgccaccaaacccagaggaaaagaaaaaaaaggaccgattttaccgagccatcttacct
ggagataaaacaaataaaaagaaggagaaggaacggccagagatttctcttccttcagat
tttgagcacacgattcacgttggttttgatgctgtcacaggcgagtttacagggatgcca
gagcaatgggcccgcttgcttcagacatcaaatatcactaagtcggagcagaagaaaaac
ccgcaggctgttctggatgtgttggaattttataactcaaagaagacctccaacagccag
aagtatatgagctttacagataaatcagctgaggattataattcttctaacactttgaat
gtgaaggcggtgtctgagacccctgcggtgccaccagtttcagaagatgaagatgatgat
gatgatggcaccccacccccagtgattgctccacgcccagagcacacaaaatctgtatac
acacggtctgtgattgaaccacttcctattactccaactcgggatgtggctacatctccc
atttcacctactgagaataataccactccacctgatgctctgactcggaatactgagaag
cagaagaagaagcctaagatgtctgatgaggagatcttggagaaattacgcagcatagtg
agtgtgggtgatcctaagaagaaatacacacggtttgagaagattggacaaggtgcttcg
ggcactgtgtacactgcaatggatgtagccacaggacaggaggtggccattaagcagatg
aaccttcagcagcagccgaagaaagagctgattattaatgagatcctggtcatgagggaa
aacaagaacccaaatattgtgaactacttggacagttaccttgtgggagatgagctatgg
gttgtcatggaatatttggctggaggttctttgacagatgtggtaacagaaacttgcatg
gacgaaggtcagattgcagctgtgtgccgtgagtgcctgcaagctttggagtttctgcat
tcgaaccaagttattcatagagacatcaagagtgacaacatcctgttgggaatggatggc
tctgtcaagttaactgattttggattttgtgctcagatcaccccagagcagagcaaacgg
agcaccatggtgggaacaccgtactggatggcaccagaggttgtaacccggaaagcctat
gggcctaaggttgacatttggtccttgggcatcatggccattgaaatgattgaaggggag
cccccatacctcaacgaaaaccctctgagagccttgtacctcattgccaccaatgggacc
ccagagcttcagaacccagagaagctgtcagctatcttccgagactttctgaaccgctgt
cttgagatggatgtggagaagagaggttcggctaaagaactgctgcagcatcaatttctg
aagattgccaagcctctctccagcctcactccactgattgctgctgcaaaggaagcaacc
aagaacaatcactaa

DBGET integrated database retrieval system