Entry
Symbol
PAK1
Name
Pathway
map04392 Hippo signaling pathway - multiple species
map04625 C-type lectin receptor signaling pathway
map04650 Natural killer cell mediated cytotoxicity
map04660 T cell receptor signaling pathway
map04666 Fc gamma R-mediated phagocytosis
map04810 Regulation of actin cytoskeleton
map05120 Epithelial cell signaling in Helicobacter pylori infection
map05130 Pathogenic Escherichia coli infection
map05170 Human immunodeficiency virus 1 infection
Disease
H02463 Syndromic intellectual developmental disorder
Brite
KEGG Orthology (KO) [BR:ko00001 ]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
K04409 PAK1; p21-activated kinase 1
04011 MAPK signaling pathway - yeast
K04409 PAK1; p21-activated kinase 1
04012 ErbB signaling pathway
K04409 PAK1; p21-activated kinase 1
04014 Ras signaling pathway
K04409 PAK1; p21-activated kinase 1
04392 Hippo signaling pathway - multiple species
K04409 PAK1; p21-activated kinase 1
04024 cAMP signaling pathway
K04409 PAK1; p21-activated kinase 1
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
K04409 PAK1; p21-activated kinase 1
09142 Cell motility
04810 Regulation of actin cytoskeleton
K04409 PAK1; p21-activated kinase 1
09150 Organismal Systems
09151 Immune system
04625 C-type lectin receptor signaling pathway
K04409 PAK1; p21-activated kinase 1
04650 Natural killer cell mediated cytotoxicity
K04409 PAK1; p21-activated kinase 1
04660 T cell receptor signaling pathway
K04409 PAK1; p21-activated kinase 1
04666 Fc gamma R-mediated phagocytosis
K04409 PAK1; p21-activated kinase 1
04062 Chemokine signaling pathway
K04409 PAK1; p21-activated kinase 1
09158 Development and regeneration
04360 Axon guidance
K04409 PAK1; p21-activated kinase 1
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
K04409 PAK1; p21-activated kinase 1
09162 Cancer: specific types
05211 Renal cell carcinoma
K04409 PAK1; p21-activated kinase 1
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
K04409 PAK1; p21-activated kinase 1
09171 Infectious disease: bacterial
05120 Epithelial cell signaling in Helicobacter pylori infection
K04409 PAK1; p21-activated kinase 1
05130 Pathogenic Escherichia coli infection
K04409 PAK1; p21-activated kinase 1
05132 Salmonella infection
K04409 PAK1; p21-activated kinase 1
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases
K04409 PAK1; p21-activated kinase 1
09182 Protein families: genetic information processing
04131 Membrane trafficking
K04409 PAK1; p21-activated kinase 1
03036 Chromosome and associated proteins
K04409 PAK1; p21-activated kinase 1
Enzymes [BR:ko01000 ]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
K04409 PAK1; p21-activated kinase 1
Protein kinases [BR:ko01001 ]
Serine/threonine kinases: STE group
STE20 family
K04409 PAK1; p21-activated kinase 1
Membrane trafficking [BR:ko04131 ]
Exocytosis
Calcium ion-dependent exocytosis
Kinases and associated proteins
K04409 PAK1; p21-activated kinase 1
Endocytosis
Macropinocytosis
Kinases
K04409 PAK1; p21-activated kinase 1
Chromosome and associated proteins [BR:ko03036 ]
Eukaryotic type
Sister chromatid separation proteins
Aurora kinases
Regulators of Aurora kinases
K04409 PAK1; p21-activated kinase 1
BRITE hierarchy
Other DBs
Genes
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Taxonomy UniProt
Reference
Authors
Brown JL, Stowers L, Baer M, Trejo J, Coughlin S, Chant J
Title
Human Ste20 homologue hPAK1 links GTPases to the JNK MAP kinase pathway.
Journal
Sequence
Reference
Authors
Zhao ZS, Lim JP, Ng YW, Lim L, Manser E
Title
The GIT-associated kinase PAK targets to the centrosome and regulates Aurora-A.
Journal
Reference
Authors
Leberer E, Dignard D, Harcus D, Thomas DY, Whiteway M
Title
The protein kinase homologue Ste20p is required to link the yeast pheromone response G-protein beta gamma subunits to downstream signalling components.
Journal
Sequence
LinkDB
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