KEGG   Bison bison bison (American bison): 104999231
Entry
104999231         CDS       T08726                                 
Symbol
BCL2
Name
(RefSeq) apoptosis regulator Bcl-2 isoform X1
  KO
K02161  apoptosis regulator Bcl-2
Organism
bbis  Bison bison bison (American bison)
Pathway
bbis01521  EGFR tyrosine kinase inhibitor resistance
bbis01522  Endocrine resistance
bbis01524  Platinum drug resistance
bbis04064  NF-kappa B signaling pathway
bbis04066  HIF-1 signaling pathway
bbis04071  Sphingolipid signaling pathway
bbis04115  p53 signaling pathway
bbis04140  Autophagy - animal
bbis04141  Protein processing in endoplasmic reticulum
bbis04151  PI3K-Akt signaling pathway
bbis04210  Apoptosis
bbis04215  Apoptosis - multiple species
bbis04217  Necroptosis
bbis04261  Adrenergic signaling in cardiomyocytes
bbis04340  Hedgehog signaling pathway
bbis04510  Focal adhesion
bbis04621  NOD-like receptor signaling pathway
bbis04630  JAK-STAT signaling pathway
bbis04722  Neurotrophin signaling pathway
bbis04725  Cholinergic synapse
bbis04915  Estrogen signaling pathway
bbis04928  Parathyroid hormone synthesis, secretion and action
bbis04933  AGE-RAGE signaling pathway in diabetic complications
bbis05014  Amyotrophic lateral sclerosis
bbis05022  Pathways of neurodegeneration - multiple diseases
bbis05132  Salmonella infection
bbis05145  Toxoplasmosis
bbis05152  Tuberculosis
bbis05161  Hepatitis B
bbis05162  Measles
bbis05168  Herpes simplex virus 1 infection
bbis05169  Epstein-Barr virus infection
bbis05170  Human immunodeficiency virus 1 infection
bbis05200  Pathways in cancer
bbis05206  MicroRNAs in cancer
bbis05207  Chemical carcinogenesis - receptor activation
bbis05210  Colorectal cancer
bbis05215  Prostate cancer
bbis05222  Small cell lung cancer
bbis05226  Gastric cancer
bbis05417  Lipid and atherosclerosis
bbis05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:bbis00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    104999231 (BCL2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04340 Hedgehog signaling pathway
    104999231 (BCL2)
   04630 JAK-STAT signaling pathway
    104999231 (BCL2)
   04064 NF-kappa B signaling pathway
    104999231 (BCL2)
   04066 HIF-1 signaling pathway
    104999231 (BCL2)
   04071 Sphingolipid signaling pathway
    104999231 (BCL2)
   04151 PI3K-Akt signaling pathway
    104999231 (BCL2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    104999231 (BCL2)
  09143 Cell growth and death
   04210 Apoptosis
    104999231 (BCL2)
   04215 Apoptosis - multiple species
    104999231 (BCL2)
   04217 Necroptosis
    104999231 (BCL2)
   04115 p53 signaling pathway
    104999231 (BCL2)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    104999231 (BCL2)
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    104999231 (BCL2)
  09152 Endocrine system
   04915 Estrogen signaling pathway
    104999231 (BCL2)
   04928 Parathyroid hormone synthesis, secretion and action
    104999231 (BCL2)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    104999231 (BCL2)
  09156 Nervous system
   04725 Cholinergic synapse
    104999231 (BCL2)
   04722 Neurotrophin signaling pathway
    104999231 (BCL2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    104999231 (BCL2)
   05206 MicroRNAs in cancer
    104999231 (BCL2)
   05207 Chemical carcinogenesis - receptor activation
    104999231 (BCL2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    104999231 (BCL2)
   05226 Gastric cancer
    104999231 (BCL2)
   05215 Prostate cancer
    104999231 (BCL2)
   05222 Small cell lung cancer
    104999231 (BCL2)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    104999231 (BCL2)
   05161 Hepatitis B
    104999231 (BCL2)
   05162 Measles
    104999231 (BCL2)
   05168 Herpes simplex virus 1 infection
    104999231 (BCL2)
   05169 Epstein-Barr virus infection
    104999231 (BCL2)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    104999231 (BCL2)
   05152 Tuberculosis
    104999231 (BCL2)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    104999231 (BCL2)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    104999231 (BCL2)
   05022 Pathways of neurodegeneration - multiple diseases
    104999231 (BCL2)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    104999231 (BCL2)
   05418 Fluid shear stress and atherosclerosis
    104999231 (BCL2)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    104999231 (BCL2)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    104999231 (BCL2)
   01524 Platinum drug resistance
    104999231 (BCL2)
   01522 Endocrine resistance
    104999231 (BCL2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:bbis01009]
    104999231 (BCL2)
Protein phosphatases and associated proteins [BR:bbis01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     104999231 (BCL2)
SSDB
Motif
Pfam: Bcl-2 BH4 Bcl-2_3 ARMH5
Other DBs
NCBI-GeneID: 104999231
NCBI-ProteinID: XP_010853042
Ensembl: ENSBBBG00000005779
UniProt: A0A6P3IMG3
LinkDB
Position
Unknown
AA seq 229 aa
MAHAGGTGYDNREIVMKYIHYKLSQRGYEWDAGDAGAAPPGAAPAPGILSSQPGRTPAPS
RTSPPPPPAAAAGPAPSPVPPVVHLTLRQAGDDFSRRYRRDFAEMSSQLHLTPFTARGRF
ATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDSIALWMTEYLNRHLHTWIQ
DNGGWDAFVELYGPSMRPLFDFSWLSLKALLSLALVGACITLGAYLGHK
NT seq 690 nt   +upstreamnt  +downstreamnt
atggcgcacgcggggggaacaggctacgataaccgagagatcgtgatgaagtacatccac
tataagctgtcgcagcggggctacgagtgggatgccggagacgcgggcgccgcgcccccc
ggggccgctcccgcgccgggcatcctgtcctcccagccgggccgcacacccgcgccctcc
aggacctccccgccgccgcccccggccgccgccgccgggcctgcgcccagcccggtgccg
cctgtggtgcacctgaccctgcgccaggccggcgatgacttctctcggcgctaccgccgc
gacttcgccgagatgtccagtcaactgcacctgacgcccttcaccgcgaggggacgcttc
gccacggtggtggaggagctcttcagggacggggtgaactgggggcgcatcgtggccttc
tttgagttcggaggggtcatgtgtgtggagagcgtcaaccgggagatgtcgcccctggtg
gacagcatcgccctgtggatgaccgagtacctgaaccggcacctgcacacctggatccag
gacaacggaggctgggacgcctttgtggagctgtatggccctagcatgcggcccctgttt
gatttctcctggctgtctctgaaggcactgctcagtctggccctggtgggcgcttgcatc
accctgggtgcctatctgggccataagtga

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