Bison bison bison (American bison): 104999328
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Entry
104999328 CDS
T08726
Symbol
ITCH
Name
(RefSeq) E3 ubiquitin-protein ligase Itchy homolog
KO
K05632
E3 ubiquitin-protein ligase Itchy [EC:
2.3.2.26
]
Organism
bbis
Bison bison bison (American bison)
Pathway
bbis04120
Ubiquitin mediated proteolysis
bbis04144
Endocytosis
bbis04330
Notch signaling pathway
bbis04668
TNF signaling pathway
bbis04932
Non-alcoholic fatty liver disease
Brite
KEGG Orthology (KO) [BR:
bbis00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
104999328 (ITCH)
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
104999328 (ITCH)
04668 TNF signaling pathway
104999328 (ITCH)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
104999328 (ITCH)
09160 Human Diseases
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
104999328 (ITCH)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
bbis04131
]
104999328 (ITCH)
04121 Ubiquitin system [BR:
bbis04121
]
104999328 (ITCH)
Enzymes [BR:
bbis01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
104999328 (ITCH)
Membrane trafficking [BR:
bbis04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
104999328 (ITCH)
Ubiquitin system [BR:
bbis04121
]
Ubiquitin ligases (E3)
HECT type E3
104999328 (ITCH)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
HECT
WW
C2
Motif
Other DBs
NCBI-GeneID:
104999328
NCBI-ProteinID:
XP_010853176
UniProt:
A0A6P3IFD7
LinkDB
All DBs
Position
Unknown
AA seq
862 aa
AA seq
DB search
MSDSGSQLGSMGSLTMKSQLQITVISAKLKENKKNWFGPSPYVEVTVDGQSKKTEKCNNT
NSPKWKQPLTVIVTPVSKLHFRVWSHQTLKSDVLLGTAGLDIYETLKSNNMKLEEVVVTL
QLVGDKEPAETIGDLSVCLDGLQLESEVVANGETACSESASHNDDGSRPKDETRANASGS
DDPEDAGSGENRRINGNNSPSLSNGGFKPSRPPRPSRPPPPTPRRPASVNGSPSTTSESD
GSSTGSLPPTNTNSSTSEGATSGLIIPLTISGGAGPRPLNPVPQAPLPPGWEQRVDQHGR
VYYVDHIEKRTTWDRPEPLPPGWERRVDNMGRIYYVDHFTRTTTWQRPTLESVRNYEQWQ
LQRSQLQGAMQQFNQRFIYGNQDLFATSQNKEFDPLGPLPPGWEKRTDSNGRVYFVNHNT
RITQWEDPRNQGQLNEKPLPEGWEMRFTVDGIPYFVDHNRRTTTYIDPRTGKSALDNGPQ
IAYVRDFKAKVQYFRFWCQQLAMPQHIKITVTRKTLFEDSFQQIMSFSPQDLRRRLWVIF
PGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFRFI
GRFIAMALFHGKFIDTGFSLPFYKRILNKPVGLKDLESIDPEFYNSLIWVKENNIEECDL
EMYFSIDKEILGEIKSHDLKPNGGNILVTEENKEEYIRIVAEWRLSRGVEEQTQAFFEGF
NEILPQQYLQYFDAKELEVLLCGMQEIDLNDWQRHAIYRHYTRTSKQIMWFWQFVKEIDN
EKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEKVGKENWLPRSHTCFNRLDLPPYK
SYEQLKEKLLFAIEETEGFGQE
NT seq
2589 nt
NT seq
+upstream
nt +downstream
nt
atgtctgacagtggatcacagcttggttcaatgggtagtttgaccatgaaatcacaactt
cagatcactgtcatttcagcaaaacttaaagaaaataaaaagaattggtttgggccaagt
ccttatgtggaagtcacagtagatggacagtcaaagaagacagaaaaatgcaacaatacg
aacagtcccaaatggaagcagcctcttacagttattgtcacccctgtgagtaaattacat
tttcgtgtgtggagtcaccagacactgaaatctgatgttttgttgggaactgctggattg
gatatctatgaaacattaaagtcaaacaatatgaaacttgaggaagtagttgtgacttta
cagcttgtaggtgacaaagaaccagcagagacaataggagatttgtcagtctgtcttgat
gggctgcaactagagtctgaagttgttgccaatggtgaaactgcatgttcagaaagtgct
tcacacaatgatgatggctccaggcccaaggatgaaacaagagcgaacgcaagtggatca
gatgaccctgaggatgcagggtctggtgaaaataggaggatcaatgggaataattctcca
tcactctcaaatggcggttttaaaccttctaggcctccaagaccttcacgaccacctcca
cctaccccacgtagaccagcatctgtcaatggctcaccatctaccacttctgaaagtgat
ggctctagtacaggctctctgccaccaacaaatacaaattcaagtacatctgaaggagca
acatctggattaataattcctcttactatatctggaggtgcaggccctagaccattaaat
cctgtacctcaagctcccctcccacctggttgggagcagagagtggaccagcatgggcga
gtttactatgtagatcatattgaaaaaagaacaacgtgggatagaccagaacctctacct
cctggctgggagcggcgggttgacaacatgggacgtatttattatgttgaccatttcaca
agaacaacaacgtggcagaggccaacactggaatcagtccggaactatgaacaatggcag
ctccagcgtagtcaacttcagggagctatgcagcagtttaaccagaggttcatttatggg
aatcaagatttgtttgctacatcacaaaataaagaatttgatcccctgggtcccctgccg
cctggttgggagaagagaacggacagcaatggtagagtatattttgtcaaccacaacact
cgtattacacaatgggaagaccccagaaatcaaggtcaattaaatgaaaagcccttacct
gaaggctgggaaatgagattcacggtagacggaattccgtatttcgtggaccacaataga
agaacaaccacctatatagatccccgcaccggaaaatctgccttagacaatggaccccag
atagcctatgtacgggacttcaaggcaaaggttcaatatttccgtttctggtgtcagcaa
ctggccatgccacagcacataaagattacagtgacaagaaaaacattgtttgaggattcc
tttcagcagataatgagcttcagtcctcaagatctgcgaagacgtttgtgggtgattttt
ccaggagaagaaggtttagattatggaggtgtagcaagagaatggttctttcttttgtca
catgaggtgttgaacccaatgtattgcctgtttgaatatgcagggaaggataactactgc
ttgcagataaaccccgcttcttacatcaatccagatcacctgaaatattttcgttttatt
ggcaggtttattgctatggctctgttccatgggaaattcatagacacaggtttttctttg
ccattctataagcgtatcttgaataaaccagttggactgaaggatttagaatcgattgat
ccagaattttacaattctctcatctgggttaaagaaaacaatattgaggagtgtgatttg
gaaatgtatttctccattgataaagaaatcttaggtgaaatcaagagtcatgatttgaaa
cccaatggtggcaatattcttgtaacagaagaaaataaagaagaatatatcagaatagta
gctgaatggagattgtctcgtggtgttgaagaacagacgcaagctttctttgagggcttt
aatgaaattcttccccagcagtatctacagtacttcgatgcaaaggaattagaggttctt
ttatgtgggatgcaagagattgatttgaatgattggcaaagacatgccatctaccgtcac
tataccaggacaagtaaacaaatcatgtggttttggcagtttgttaaagaaatcgataat
gagaagagaatgcgacttttgcagtttgttactgggacctgccgactgccagttggagga
tttgctgacctcatggggagcaatgggccacagaagttctgcattgaaaaagtcgggaaa
gaaaattggttgcctagaagtcatacctgttttaaccgcctggacctgccaccctacaag
agctatgagcaactgaaggaaaagctgttatttgctattgaagaaacagaaggctttgga
caagagtga
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