KEGG   Bison bison bison (American bison): 105000057
Entry
105000057         CDS       T08726                                 
Symbol
FOS
Name
(RefSeq) proto-oncogene c-Fos
  KO
K04379  proto-oncogene protein c-fos
Organism
bbis  Bison bison bison (American bison)
Pathway
bbis01522  Endocrine resistance
bbis04010  MAPK signaling pathway
bbis04024  cAMP signaling pathway
bbis04210  Apoptosis
bbis04380  Osteoclast differentiation
bbis04620  Toll-like receptor signaling pathway
bbis04657  IL-17 signaling pathway
bbis04658  Th1 and Th2 cell differentiation
bbis04659  Th17 cell differentiation
bbis04660  T cell receptor signaling pathway
bbis04662  B cell receptor signaling pathway
bbis04668  TNF signaling pathway
bbis04713  Circadian entrainment
bbis04725  Cholinergic synapse
bbis04728  Dopaminergic synapse
bbis04915  Estrogen signaling pathway
bbis04917  Prolactin signaling pathway
bbis04921  Oxytocin signaling pathway
bbis04926  Relaxin signaling pathway
bbis04928  Parathyroid hormone synthesis, secretion and action
bbis04932  Non-alcoholic fatty liver disease
bbis04935  Growth hormone synthesis, secretion and action
bbis05031  Amphetamine addiction
bbis05132  Salmonella infection
bbis05133  Pertussis
bbis05135  Yersinia infection
bbis05140  Leishmaniasis
bbis05142  Chagas disease
bbis05161  Hepatitis B
bbis05162  Measles
bbis05166  Human T-cell leukemia virus 1 infection
bbis05167  Kaposi sarcoma-associated herpesvirus infection
bbis05170  Human immunodeficiency virus 1 infection
bbis05171  Coronavirus disease - COVID-19
bbis05200  Pathways in cancer
bbis05207  Chemical carcinogenesis - receptor activation
bbis05208  Chemical carcinogenesis - reactive oxygen species
bbis05210  Colorectal cancer
bbis05224  Breast cancer
bbis05231  Choline metabolism in cancer
bbis05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
bbis05323  Rheumatoid arthritis
bbis05417  Lipid and atherosclerosis
bbis05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:bbis00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    105000057 (FOS)
   04668 TNF signaling pathway
    105000057 (FOS)
   04024 cAMP signaling pathway
    105000057 (FOS)
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    105000057 (FOS)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    105000057 (FOS)
   04660 T cell receptor signaling pathway
    105000057 (FOS)
   04658 Th1 and Th2 cell differentiation
    105000057 (FOS)
   04659 Th17 cell differentiation
    105000057 (FOS)
   04657 IL-17 signaling pathway
    105000057 (FOS)
   04662 B cell receptor signaling pathway
    105000057 (FOS)
  09152 Endocrine system
   04915 Estrogen signaling pathway
    105000057 (FOS)
   04917 Prolactin signaling pathway
    105000057 (FOS)
   04921 Oxytocin signaling pathway
    105000057 (FOS)
   04926 Relaxin signaling pathway
    105000057 (FOS)
   04935 Growth hormone synthesis, secretion and action
    105000057 (FOS)
   04928 Parathyroid hormone synthesis, secretion and action
    105000057 (FOS)
  09156 Nervous system
   04725 Cholinergic synapse
    105000057 (FOS)
   04728 Dopaminergic synapse
    105000057 (FOS)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    105000057 (FOS)
  09159 Environmental adaptation
   04713 Circadian entrainment
    105000057 (FOS)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    105000057 (FOS)
   05207 Chemical carcinogenesis - receptor activation
    105000057 (FOS)
   05208 Chemical carcinogenesis - reactive oxygen species
    105000057 (FOS)
   05231 Choline metabolism in cancer
    105000057 (FOS)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    105000057 (FOS)
  09162 Cancer: specific types
   05210 Colorectal cancer
    105000057 (FOS)
   05224 Breast cancer
    105000057 (FOS)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    105000057 (FOS)
   05170 Human immunodeficiency virus 1 infection
    105000057 (FOS)
   05161 Hepatitis B
    105000057 (FOS)
   05171 Coronavirus disease - COVID-19
    105000057 (FOS)
   05162 Measles
    105000057 (FOS)
   05167 Kaposi sarcoma-associated herpesvirus infection
    105000057 (FOS)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    105000057 (FOS)
   05135 Yersinia infection
    105000057 (FOS)
   05133 Pertussis
    105000057 (FOS)
  09174 Infectious disease: parasitic
   05140 Leishmaniasis
    105000057 (FOS)
   05142 Chagas disease
    105000057 (FOS)
  09163 Immune disease
   05323 Rheumatoid arthritis
    105000057 (FOS)
  09165 Substance dependence
   05031 Amphetamine addiction
    105000057 (FOS)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    105000057 (FOS)
   05418 Fluid shear stress and atherosclerosis
    105000057 (FOS)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    105000057 (FOS)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    105000057 (FOS)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:bbis03000]
    105000057 (FOS)
   04131 Membrane trafficking [BR:bbis04131]
    105000057 (FOS)
Transcription factors [BR:bbis03000]
 Eukaryotic type
  Basic leucine zipper (bZIP)
   AP-1(-like) components, Fos
    105000057 (FOS)
Membrane trafficking [BR:bbis04131]
 Autophagy
  Chaperone mediated autophagy (CMA)
   Selective cargos
    105000057 (FOS)
SSDB
Motif
Pfam: bZIP_1 bZIP_2 bZIP_Maf MIC19_MIC25 DUF3450 HALZ Macoilin
Other DBs
NCBI-GeneID: 105000057
NCBI-ProteinID: XP_010854023
Ensembl: ENSBBBG00000014386
UniProt: A0A6P3II01
LinkDB
Position
Unknown
AA seq 380 aa
MMFSGFNADYEASSSRCSSASPAGDSLSYYHSPADSFSSMGSPVNAQDYCTDLAVSSANF
IPTVTAISTSPDLQWLVQPTLVSSVAPSQTRAPHPYGVPTPSAGAYSRAGVMKTMTGGRA
QSIGRRGKVEQLSPEEEEKRRIRRERNKMAAAKCRNRRRELTDTLQAETDQLEDEKSALQ
TEIANLLKEKEKLEFILAAHRPACKIPDDLGFPEEMSVASLDLSGGLPEAATPESEEAFT
LPLLNDPEPKPSVEPVKSVGSMELKAEPFDDYMFPASSRPSGSETARSVPDMDLSGSFYA
ADWEPLHGGSLGMGPMATELEPLCTPVVTCTPSCTTYTSSFVFTYPEADSFPSCAAAHRK
GSSSNEPSSDSLSSPTLLAL
NT seq 1143 nt   +upstreamnt  +downstreamnt
atgatgttctctggcttcaacgccgactacgaggcatcctcctcccgctgcagcagcgcc
tccccggccggggacagtctctcctactaccactcaccggccgactccttctccagcatg
ggttctcccgtcaatgcgcaggactactgcaccgatctggccgtctccagtgccaacttc
atcccaacagtgactgccatctcgaccagcccggacctacaatggctagtacagcccacc
ctagtctcctccgtggccccgtcccagaccagagccccccacccctatggagtccctact
ccctcagctggggcttactccagggctggagtcatgaaaaccatgacaggaggcagagct
cagagcattggccggaggggcaaggtagaacagttgtccccagaagaagaagagaaaagg
cgaatccgaagggaaaggaataaaatggctgcagccaaatgccggaaccggaggagggag
ctgactgacaccctccaagcggagacagaccaactagaagatgagaagtcggctttgcag
acagagattgccaatctgctgaaggagaaggaaaaactcgagttcatcctagcggctcac
cgacctgcctgcaagatccccgatgacctgggcttcccagaagagatgtctgtggcttct
cttgatctgagtgggggcctgcctgaggctgccacccctgaatctgaggaggccttcacc
ctgccactcctcaatgaccctgagcccaagccctcagtggagcccgtcaagagcgtcggc
agcatggagctgaaggctgagccctttgatgactacatgttcccagcatcatccaggccc
agcggctcggagaccgcccgctctgtgccagacatggacctgtctggttccttctatgca
gcagactgggagcccctgcatggtggctccctggggatggggcctatggccacggagctg
gagcccctgtgcaccccggtggtcacctgtactcccagctgcactacttacacgtcttcc
ttcgtcttcacctaccctgaggctgactccttccccagctgtgcggctgcccaccgcaag
ggcagcagcagcaacgagccttcctctgactcgctcagctcacccacgctgctggccctg
tga

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