K04379                      KO                                     
proto-oncogene protein c-fos
map01522  Endocrine resistance
map04010  MAPK signaling pathway
map04024  cAMP signaling pathway
map04210  Apoptosis
map04380  Osteoclast differentiation
map04620  Toll-like receptor signaling pathway
map04657  IL-17 signaling pathway
map04658  Th1 and Th2 cell differentiation
map04659  Th17 cell differentiation
map04660  T cell receptor signaling pathway
map04662  B cell receptor signaling pathway
map04668  TNF signaling pathway
map04713  Circadian entrainment
map04725  Cholinergic synapse
map04728  Dopaminergic synapse
map04915  Estrogen signaling pathway
map04917  Prolactin signaling pathway
map04921  Oxytocin signaling pathway
map04926  Relaxin signaling pathway
map04928  Parathyroid hormone synthesis, secretion and action
map04932  Non-alcoholic fatty liver disease
map04935  Growth hormone synthesis, secretion and action
map05031  Amphetamine addiction
map05130  Pathogenic Escherichia coli infection
map05132  Salmonella infection
map05133  Pertussis
map05135  Yersinia infection
map05140  Leishmaniasis
map05142  Chagas disease
map05161  Hepatitis B
map05162  Measles
map05166  Human T-cell leukemia virus 1 infection
map05167  Kaposi sarcoma-associated herpesvirus infection
map05170  Human immunodeficiency virus 1 infection
map05171  Coronavirus disease - COVID-19
map05200  Pathways in cancer
map05207  Chemical carcinogenesis - receptor activation
map05208  Chemical carcinogenesis - reactive oxygen species
map05210  Colorectal cancer
map05224  Breast cancer
map05231  Choline metabolism in cancer
map05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
map05323  Rheumatoid arthritis
map05417  Lipid and atherosclerosis
map05418  Fluid shear stress and atherosclerosis
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K04379  FOS; proto-oncogene protein c-fos
   04668 TNF signaling pathway
    K04379  FOS; proto-oncogene protein c-fos
   04024 cAMP signaling pathway
    K04379  FOS; proto-oncogene protein c-fos
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    K04379  FOS; proto-oncogene protein c-fos
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    K04379  FOS; proto-oncogene protein c-fos
   04660 T cell receptor signaling pathway
    K04379  FOS; proto-oncogene protein c-fos
   04658 Th1 and Th2 cell differentiation
    K04379  FOS; proto-oncogene protein c-fos
   04659 Th17 cell differentiation
    K04379  FOS; proto-oncogene protein c-fos
   04657 IL-17 signaling pathway
    K04379  FOS; proto-oncogene protein c-fos
   04662 B cell receptor signaling pathway
    K04379  FOS; proto-oncogene protein c-fos
  09152 Endocrine system
   04915 Estrogen signaling pathway
    K04379  FOS; proto-oncogene protein c-fos
   04917 Prolactin signaling pathway
    K04379  FOS; proto-oncogene protein c-fos
   04921 Oxytocin signaling pathway
    K04379  FOS; proto-oncogene protein c-fos
   04926 Relaxin signaling pathway
    K04379  FOS; proto-oncogene protein c-fos
   04935 Growth hormone synthesis, secretion and action
    K04379  FOS; proto-oncogene protein c-fos
   04928 Parathyroid hormone synthesis, secretion and action
    K04379  FOS; proto-oncogene protein c-fos
  09156 Nervous system
   04725 Cholinergic synapse
    K04379  FOS; proto-oncogene protein c-fos
   04728 Dopaminergic synapse
    K04379  FOS; proto-oncogene protein c-fos
  09158 Development and regeneration
   04380 Osteoclast differentiation
    K04379  FOS; proto-oncogene protein c-fos
  09159 Environmental adaptation
   04713 Circadian entrainment
    K04379  FOS; proto-oncogene protein c-fos
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K04379  FOS; proto-oncogene protein c-fos
   05207 Chemical carcinogenesis - receptor activation
    K04379  FOS; proto-oncogene protein c-fos
   05208 Chemical carcinogenesis - reactive oxygen species
    K04379  FOS; proto-oncogene protein c-fos
   05231 Choline metabolism in cancer
    K04379  FOS; proto-oncogene protein c-fos
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    K04379  FOS; proto-oncogene protein c-fos
  09162 Cancer: specific types
   05210 Colorectal cancer
    K04379  FOS; proto-oncogene protein c-fos
   05224 Breast cancer
    K04379  FOS; proto-oncogene protein c-fos
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K04379  FOS; proto-oncogene protein c-fos
   05170 Human immunodeficiency virus 1 infection
    K04379  FOS; proto-oncogene protein c-fos
   05161 Hepatitis B
    K04379  FOS; proto-oncogene protein c-fos
   05171 Coronavirus disease - COVID-19
    K04379  FOS; proto-oncogene protein c-fos
   05162 Measles
    K04379  FOS; proto-oncogene protein c-fos
   05167 Kaposi sarcoma-associated herpesvirus infection
    K04379  FOS; proto-oncogene protein c-fos
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    K04379  FOS; proto-oncogene protein c-fos
   05132 Salmonella infection
    K04379  FOS; proto-oncogene protein c-fos
   05135 Yersinia infection
    K04379  FOS; proto-oncogene protein c-fos
   05133 Pertussis
    K04379  FOS; proto-oncogene protein c-fos
  09174 Infectious disease: parasitic
   05140 Leishmaniasis
    K04379  FOS; proto-oncogene protein c-fos
   05142 Chagas disease
    K04379  FOS; proto-oncogene protein c-fos
  09163 Immune disease
   05323 Rheumatoid arthritis
    K04379  FOS; proto-oncogene protein c-fos
  09165 Substance dependence
   05031 Amphetamine addiction
    K04379  FOS; proto-oncogene protein c-fos
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    K04379  FOS; proto-oncogene protein c-fos
   05418 Fluid shear stress and atherosclerosis
    K04379  FOS; proto-oncogene protein c-fos
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    K04379  FOS; proto-oncogene protein c-fos
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    K04379  FOS; proto-oncogene protein c-fos
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K04379  FOS; proto-oncogene protein c-fos
   04131 Membrane trafficking
    K04379  FOS; proto-oncogene protein c-fos
Transcription factors [BR:ko03000]
 Eukaryotic type
  Basic leucine zipper (bZIP)
   AP-1(-like) components, Fos
    K04379  FOS; proto-oncogene protein c-fos
Membrane trafficking [BR:ko04131]
  Chaperone mediated autophagy (CMA)
   Selective cargos
    K04379  FOS; proto-oncogene protein c-fos
HSA: 2353(FOS)
PTR: 453047(FOS)
PPS: 100987957(FOS)
GGO: 101127590(FOS)
PON: 100462290(FOS)
NLE: 100585899(FOS)
HMH: 116456218(FOS)
MCC: 702077(FOS)
MCF: 102143716(FOS)
MTHB: 126959543
MNI: 105495778(FOS)
CSAB: 103229352(FOS)
CATY: 105590868(FOS)
PANU: 101021141(FOS)
TGE: 112628560(FOS)
MLEU: 105540805(FOS)
RRO: 104677590(FOS)
RBB: 108534930(FOS)
TFN: 117069314(FOS)
PTEH: 111521118(FOS)
CANG: 105517139(FOS)
CJC: 100390054(FOS)
SBQ: 101046701(FOS)
CIMI: 108304440(FOS)
CSYR: 103266527(FOS)
MMUR: 105858849(FOS)
LCAT: 123646534(FOS)
PCOQ: 105819831(FOS)
OGA: 100953435(FOS)
MMU: 14281(Fos)
MCAL: 110307063(Fos)
MPAH: 110324365(Fos)
RNO: 314322(Fos)
MCOC: 116080518(Fos)
ANU: 117697448(Fos)
MUN: 110546962(Fos)
CGE: 100689418(Fos)
MAUA: 101831721(Fos)
PROB: 127230991(Fos)
PLEU: 114698038(Fos)
MORG: 121452580(Fos)
MFOT: 126515189
AAMP: 119819161(Fos)
NGI: 103747342(Fos)
HGL: 101718383(Fos)
CPOC: 100713572(Fos)
CCAN: 109694000(Fos)
DORD: 105986734(Fos)
DSP: 122118881(Fos)
PLOP: 125363230(Fos)
NCAR: 124977967
MMMA: 107149351(Fos)
OCU: 100338345
OPI: 101526067(FOS)
TUP: 102491199(FOS)
GVR: 103605891(FOS)
CFA: 490792(FOS)
CLUD: 112657374(FOS)
VVP: 112927292(FOS)
VLG: 121493811(FOS)
NPO: 129496401(FOS)
AML: 100474867(FOS)
UMR: 103671011(FOS)
UAH: 113270317(FOS)
UAR: 123798968(FOS)
ELK: 111148602
LLV: 125105343
MPUF: 101685236(FOS)
MNP: 132000157(FOS)
MLK: 131836857(FOS)
NVS: 122893478(FOS)
ORO: 101366773(FOS)
EJU: 114207358(FOS)
ZCA: 113910278(FOS)
MLX: 118002212(FOS)
NSU: 110571456(FOS)
LWW: 102727855(FOS)
FCA: 493935(FOS)
PYU: 121032071(FOS)
PCOO: 112854981(FOS)
PBG: 122469346(FOS)
PVIV: 125168871(FOS)
LRUF: 124512631
PTG: 102952769(FOS)
PPAD: 109253856(FOS)
PUC: 125909334
AJU: 106974355
HHV: 120231952(FOS)
BTA: 280795(FOS)
BOM: 102275053(FOS)
BIU: 109565363(FOS)
BBUB: 102393791(FOS)
BBIS: 105000057(FOS)
CHX: 102171520(FOS)
OAS: 443218(FOS)
BTAX: 128053951(FOS)
ODA: 120852702(FOS)
CCAD: 122443873(FOS)
MBEZ: 129563123(FOS)
SSC: 100144486(FOS)
CFR: 102519397(FOS)
CBAI: 105075289(FOS)
CDK: 105086086(FOS)
VPC: 102533186(FOS)
BACU: 102997242(FOS)
BMUS: 118890999(FOS)
LVE: 103072956 103084433(FOS)
OOR: 101286650(FOS)
DLE: 111176238(FOS)
PCAD: 102982453(FOS)
PSIU: 116749519(FOS)
NASI: 112394907(FOS)
ECB: 100051632(FOS)
EPZ: 103548618(FOS)
EAI: 106827712(FOS)
MYB: 102246307(FOS)
MYD: 102764239(FOS)
MMYO: 118658230(FOS)
MLF: 102417433(FOS)
PKL: 118715156(FOS)
EFUS: 103283560(FOS)
MNA: 107533821(FOS)
DRO: 112311412(FOS)
SHON: 118976823(FOS)
AJM: 119049259(FOS)
PDIC: 114493153(FOS)
PHAS: 123808226(FOS)
MMF: 118618599(FOS)
PPAM: 129065732(FOS)
HAI: 109381526(FOS)
RFQ: 117024158(FOS)
PALE: 102891428(FOS)
PGIG: 120619517(FOS)
PVP: 105299213(FOS)
RAY: 107498912(FOS)
MJV: 108402534(FOS)
TOD: 119238328(FOS)
SARA: 101545059(FOS)
LAV: 100674799(FOS)
TMU: 101357016
ETF: 101656124(FOS)
DNM: 101431782(FOS)
MDO: 100018285(FOS)
GAS: 123237804(FOS)
SHR: 100924435(FOS)
AFZ: 127549484
PCW: 110208312(FOS)
OAA: 100075021(FOS)
GGA: 396512(FOS)
PCOC: 116229416(FOS)
MGP: 104916287
CJO: 107315165(FOS)
TPAI: 128086968(FOS)
LMUT: 125695245(FOS)
NMEL: 110400992(FOS)
APLA: 101801698(FOS)
CATA: 118244473(FOS)
AFUL: 116489845(FOS)
TGU: 100222961(FOS)
LSR: 110477175(FOS)
SCAN: 103826521(FOS)
PMOA: 120500400(FOS)
OTC: 121333162(FOS)
PRUF: 121355973(FOS)
GFR: 102037526(FOS)
FAB: 101807505(FOS)
OMA: 130266853(FOS)
PHI: 102103181(FOS)
PMAJ: 107206453(FOS)
CCAE: 111945660(FOS)
CCW: 104685225(FOS)
ETL: 114056015(FOS)
SVG: 106861661(FOS)
MMEA: 130578704(FOS)
HRT: 120754638(FOS)
FPG: 101921708(FOS)
CLV: 102098648(FOS)
ACUN: 113480870(FOS)
TALA: 116959628(FOS)
ACHC: 115333806(FOS)
HLE: 104841955(FOS)
AGEN: 126049369
GCL: 127017203
SHAB: 115606485(FOS)
DPUB: 104308225(FOS)
RTD: 128909213(FOS)
BRHI: 104501378(FOS)
AAM: 106483057(FOS)
AROW: 112960526(FOS)
NPD: 112957980(FOS)
TGT: 104579149(FOS)
DNE: 112995446(FOS)
ASN: 102385076(FOS)
AMJ: 102562416(FOS)
CPOO: 109321539(FOS)
GGN: 109299320(FOS)
PSS: 102454531(FOS)
CMY: 102940899(FOS)
CCAY: 125638512(FOS)
DCC: 119857951(FOS)
CPIC: 101937366(FOS)
TST: 117876830(FOS)
CABI: 116837497(FOS)
MRV: 120405405(FOS)
ACS: 100556427(fos)
ASAO: 132764361(FOS)
PVT: 110079111(FOS)
SUND: 121918920(FOS)
PBI: 103049145(FOS)
PMUR: 107285955(FOS)
CTIG: 120311766(FOS)
TSR: 106545095(FOS)
PGUT: 117665838(FOS)
APRI: 131187775(FOS)
PTEX: 113443590(FOS)
NSS: 113410033(FOS)
VKO: 123026796(FOS)
PMUA: 114591829(FOS)
PRAF: 128408950(FOS)
ZVI: 118081801(FOS)
HCG: 128340943(FOS)
GJA: 107118325(FOS)
STOW: 125427132(FOS)
EMC: 129325320(FOS)
XLA: 108698676(fos.L) 447201(fos.S)
XTR: 548954(fos)
NPR: 108802481(FOS)
RTEM: 120920284(FOS)
BBUF: 120982209(FOS)
BGAR: 122923800(FOS)
MUO: 115477396(FOS)
GSH: 117364307(FOS)
DRE: 394198(fosab) 564403(si:ch211-153j24.3) 570238(fosaa)
PTET: 122324473(si:ch211-153j24.3) 122325196(fosab) 122361624(fosaa)
LROH: 127179306(fosaa) 127183261(fosab) 127183262(si:ch211-153j24.3)
OMC: 131523270(fosaa) 131526674(fosab) 131526675(si:ch211-153j24.3)
PPRM: 120460309(si:ch211-153j24.3) 120460310(fosab) 120462345(fosaa)
RKG: 130076711(fosaa) 130103126(fosab) 130103127(si:ch211-153j24.3)
MAMB: 125268283(fosaa) 125278491(fosab) 125278492(si:ch211-153j24.3)
CIDE: 127498056 127502293 127502294(si:ch211-153j24.3)
TROS: 130560085(fosaa) 130566284(si:ch211-153j24.3) 130566285(fosab)
TDW: 130434283(fosab) 130434596(si:ch211-153j24.3) 130436958(fosaa)
MANU: 129418294(fosaa) 129429927(fosab) 129429929(si:ch211-153j24.3)
IPU: 108255380(si:ch211-153j24.3) 108260991(fosab) 108269548(fosaa) 108278451(fosl1b)
IFU: 128612582(fosaa) 128616521(si:ch211-153j24.3) 128618142(fosab)
SMEO: 124390622(fosaa) 124401612(si:ch211-153j24.3) 124401616(fosab)
TFD: 113651743(si:ch211-153j24.3) 113651782(fosab) 113659351(fosaa)
TVC: 132852110(fosaa) 132854711(si:ch211-153j24.3) 132855121(fosab)
CMAO: 118816011(fosab) 118816012(si:ch211-153j24.3) 118823609(fosaa)
CHAR: 105889778(si:ch211-153j24.3) 105889814(fosab) 105893125(fosaa)
TFS: 130516370(fosab) 130516371(si:ch211-153j24.3) 130540365(fosaa)
TBEN: 117471609(fosaa) 117493227(si:ch211-153j24.3) 117493507(fosab)
PGEO: 117440361(si:ch211-153j24.3) 117440362(fosab) 117468017
GACU: 117533795(fosab) 117533803 117549989(fosaa)
EMAC: 134876857 134876858(fosab) 134881848(fosaa)
ELY: 117270660 117270661(fosab)
EFO: 125896733 125896734(fosab)
SLUC: 116035578(fosaa) 116066178 116066292(fosab)
CLUM: 117725194(fosaa) 117727586 117727588(fosab)
PSWI: 130201320(fosaa) 130202564(fosab) 130202820
SCHU: 122862302(fosaa) 122862755(fosab) 122862756(si:ch211-153j24.3)
CUD: 121520963(fosab) 121521743(si:ch211-153j24.3) 121526444(fosaa)
OAU: 116313320(fosaa) 116314098 116314100(fosab)
OML: 112150122(fosaa) 112158236(fosab) 112158237
CSAI: 133418335(fosab) 133462543(fosaa) 133464900
CTUL: 119785058(fosab) 119785064(si:ch211-153j24.3) 119787546(fosaa)
KMR: 108233178(fosaa) 108242438(fosab) 108242442(si:ch211-153j24.3)
NWH: 119418187(fosab) 119418189 119427921(fosaa)
HHIP: 117756645(fosaa) 117758243 117758245(fosab)
SMAU: 118286690(fosaa) 118290484(si:ch211-153j24.3) 118290485(fosab)
LCF: 108892487(fosaa) 108895610(si:ch211-153j24.3) 108895611(fosab)
XGL: 120789178 120789444(fosab) 120795587(fosaa)
SSCV: 125981396 125990318 125990320(si:ch211-153j24.3)
SBIA: 133513222
PEE: 133412738(fosaa) 133417283(fosab) 133417284
PTAO: 133468338 133468339(fosab) 133487442(fosaa)
SJO: 128375379(fosaa)
LOC: 102690879(fos) 102691085
PSEX: 120518579(fosab) 120518863
LCM: 102361375(FOS)
CMK: 103189966(fos)
RTP: 109925076
CPLA: 122555597
HOC: 132818022
LERI: 129700096
BBEL: 109471128
CIN: 778607(fos)
SCLV: 120330856
TPRE: 106657453
AGIF: 122855774
CSET: 123309148
AGB: 108911388
APLN: 108738749
PPYR: 116170767
BANY: 112058375
MCIX: 123662558
OFU: 114360018
CQD: 128697682
PPOI: 119109083
DSV: 119457699
RSAN: 119373388
RMP: 119167126
BGT: 106063678
HRJ: 124268854
OED: 125649072
MMER: 123537144
OSN: 115222465
 » show all
Vesely PW, Staber PB, Hoefler G, Kenner L
Translational regulation mechanisms of AP-1 proteins.
Mutat Res 682:7-12 (2009)
van Straaten F, Muller R, Curran T, Van Beveren C, Verma IM
Complete nucleotide sequence of a human c-onc gene: deduced amino acid sequence of the human c-fos protein.
Proc Natl Acad Sci U S A 80:3183-7 (1983)
Portal MM, Ferrero GO, Caputto BL
N-Terminal c-Fos tyrosine phosphorylation regulates c-Fos/ER association and c-Fos-dependent phospholipid synthesis activation.
Oncogene 26:3551-8 (2007)

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