KEGG   Bison bison bison (American bison): 105000508
Entry
105000508         CDS       T08726                                 
Symbol
MAP3K3
Name
(RefSeq) mitogen-activated protein kinase kinase kinase 3 isoform X1
  KO
K04421  mitogen-activated protein kinase kinase kinase 3 [EC:2.7.11.25]
Organism
bbis  Bison bison bison (American bison)
Pathway
bbis04010  MAPK signaling pathway
bbis04722  Neurotrophin signaling pathway
bbis04912  GnRH signaling pathway
bbis05166  Human T-cell leukemia virus 1 infection
bbis05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:bbis00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    105000508 (MAP3K3)
 09150 Organismal Systems
  09152 Endocrine system
   04912 GnRH signaling pathway
    105000508 (MAP3K3)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    105000508 (MAP3K3)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    105000508 (MAP3K3)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    105000508 (MAP3K3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:bbis01001]
    105000508 (MAP3K3)
Enzymes [BR:bbis01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.25  mitogen-activated protein kinase kinase kinase
     105000508 (MAP3K3)
Protein kinases [BR:bbis01001]
 Serine/threonine kinases: STE group
  STE11 family
   105000508 (MAP3K3)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr PB1 ABC1 Kinase-like FTA2
Other DBs
NCBI-GeneID: 105000508
NCBI-ProteinID: XP_010854755
Ensembl: ENSBBBG00000013639
UniProt: A0A6P3IUA6
LinkDB
Position
Unknown
AA seq 647 aa
MKDLVALQMSRRPRVPGYETMKSKDTGHPNRQKKHNSSSSALLNSPTVTTSSCAGASEKK
KFLSDVRIKFEHNGERRIIAFSRPVRYEDVEHKVTAVFGQPLDLHYMNNELSILLKNQDD
LDKAIDILDRSSSMKSLRILLLSQDRNHTSSSPHSGVSRQVRIKASQSAGDINTIYQPPE
SRSRHLSVSSQNPGRSSPPPGYVPERQQRIARQGSYTSINSEGEFIPETSEQCMLDPLSS
AENSLSGSCQSLDRSADSPSFRKSRMSRAQSFPDNRQEFSDRETPLYDKGVKGGTYPRRY
HVSVHHKDYNDGRRTFPRIRRHQGNLFTLVPSSRSLSTNGENLGLAVQYLDPRARLRSAD
SENALSVQERSVPTKSPSAPINWRRGKLLGQGAFGRVYLCYDVDTGRELASKQVQFDPDS
PETSKEVSALECEIQLLKNLQHERIVQYYGCLRDRAEKTLTIFMEYMPGGSVKDQLKAYG
ALTESVTRKYTRQILEGMSYLHSNMIVHRDIKGANILRDSAGNVKLGDFGASKRLQTICM
SGTGMRSVTGTPYWMSPEVISGEGYGRKADVWSLGCTVVEMLTEKPPWAEYEAMAAIFKI
ATQPTNPQLPSHISEHGRDFLRRIFVEARQRPSAEELLTHHFAQLVY
NT seq 1944 nt   +upstreamnt  +downstreamnt
atgaaggacctggtggccctccagatgagccgacgtccccgggtgcctggatatgagacc
atgaagagcaaagacacgggtcacccaaataggcagaaaaagcacaacagcagcagctca
gcccttctgaacagccccacagtcacaacaagctcatgtgcaggggccagtgagaaaaag
aagtttttgagtgacgtcagaatcaagtttgagcacaacggggaaaggcgaattatagca
ttcagccggcctgtgagatacgaagatgtggagcacaaggtgacagcagtgttcgggcag
cctctggatctgcactacatgaacaatgagctctccatcctgctgaagaatcaagatgat
cttgacaaagcaattgacattttggatagaagctcaagcatgaaaagtcttagaatattg
ttgctgtcccaggacagaaaccataccagttcctctccccactctggggtatccaggcaa
gtgcgaatcaaagcttcccagtctgcgggagatataaataccatctaccagccccctgag
tccaggagcaggcacctctctgtcagctcccagaaccccggccgaagctcgcctccccct
ggctacgtgcctgagcggcagcagcgcatcgcccggcagggctcctacaccagcatcaac
agcgagggggagttcataccagagaccagcgagcagtgcatgctggatcctctgagcagt
gctgaaaactccttgtcgggaagctgccagtccttggacaggtcagcagacagcccatcc
ttccggaaatcacgaatgtcgcgagcccagagcttcccagacaacagacaggaattctcg
gatcgggaaactccgctctatgacaaaggggtcaaaggtggcacctacccccggcgctac
cacgtgtcggtgcaccacaaggactacaacgatggcagaagaacgtttccccgaatacgg
cgtcatcaaggcaacctgttcaccctggtgccctcgagccgctccctgagtacaaatggc
gagaacctgggcctggcggtgcagtacttggacccccgcgcgcgcctgcggagcgccgac
agcgagaacgccctctccgtgcaggagaggagtgtgcccaccaagtctcccagtgccccc
attaattggcgccgggggaagctcctaggccagggtgcctttggcagggtctatttgtgc
tatgacgtggacacaggacgagaacttgcttccaagcaggtgcagtttgacccagacagt
cctgagacaagcaaggaggtgagtgctctggagtgcgagatccagttgctgaagaacttg
cagcatgagcgcatagtgcagtactatggctgcctgcgggaccgtgccgagaagactctg
accatcttcatggagtacatgccagggggttcagtgaaagaccagctgaaggcctacggc
gctctgacagagagcgtgacccggaagtacacccggcagatactggaaggcatgtcctac
ctgcacagcaacatgattgttcaccgggacatcaagggagccaacatcctgcgagactct
gctgggaatgtgaagctgggggactttggggccagcaagcgcctgcaaaccatctgcatg
tccggcacaggcatgcgctcagtcactggcactccctactggatgagccccgaggtgatc
agcggtgagggctacggaaggaaggcagacgtgtggagcctgggctgcacggtggtggag
atgctgacagagaaaccaccttgggcagagtatgaagccatggctgccattttcaaaatc
gccacccagcccaccaaccctcagctgccctcccacatctctgagcatggccgggacttc
ctgaggcgcatttttgtggaggcccgccagagaccttcggccgaggagctgctcacacac
cactttgcacagctcgtgtactga

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