KEGG ORTHOLOGY: K04421

ORTHOLOGY: K04421

Entry

K04421                      KO

Symbol

MAP3K3, MEKK3

Name

mitogen-activated protein kinase kinase kinase 3 [EC:2.7.11.25]

Pathway

map04010

MAPK signaling pathway

map04722

Neurotrophin signaling pathway

map04912

GnRH signaling pathway

map05166

Human T-cell leukemia virus 1 infection

map05235

PD-L1 expression and PD-1 checkpoint pathway in cancer

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K04421  MAP3K3, MEKK3; mitogen-activated protein kinase kinase kinase 3
09150 Organismal Systems
  09152 Endocrine system
   04912 GnRH signaling pathway
    K04421  MAP3K3, MEKK3; mitogen-activated protein kinase kinase kinase 3
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    K04421  MAP3K3, MEKK3; mitogen-activated protein kinase kinase kinase 3
09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    K04421  MAP3K3, MEKK3; mitogen-activated protein kinase kinase kinase 3
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K04421  MAP3K3, MEKK3; mitogen-activated protein kinase kinase kinase 3
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K04421  MAP3K3, MEKK3; mitogen-activated protein kinase kinase kinase 3
Enzymes [BR:ko01000]
2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.25  mitogen-activated protein kinase kinase kinase
     K04421  MAP3K3, MEKK3; mitogen-activated protein kinase kinase kinase 3
Protein kinases [BR:ko01001]
Serine/threonine kinases: STE group
  STE11 family
   K04421  MAP3K3, MEKK3; mitogen-activated protein kinase kinase kinase 3

Other DBs

GO:

0004709

Genes

HSA:	4215(MAP3K3)

PTR:	468286(MAP3K3)

PPS:	100969705(MAP3K3)

GGO:	101148044(MAP3K3)

PON:	100444678(MAP3K3)

PPYG:

129017940(MAP3K3)

NLE:	100601763(MAP3K3)

HMH:	116458740(MAP3K3)

SSYN:

129470636(MAP3K3)

MCC:	717866(MAP3K3)

MCF:	102132095(MAP3K3)

MTHB:

126939545

MNI:	105483039(MAP3K3)

CSAB:

103243225(MAP3K3)

CATY:

105590736(MAP3K3)

PANU:

101023704(MAP3K3)

TGE:	112608888(MAP3K3)

MLEU:

105551719(MAP3K3)

RRO:	104675466(MAP3K3)

RBB:	108536280(MAP3K3)

TFN:	117067436(MAP3K3)

PTEH:

111527597(MAP3K3)

CANG:

105515973(MAP3K3)

CJC:	100409608(MAP3K3)

SBQ:	101035755(MAP3K3) 101043439

CIMI:

108318261(MAP3K3)

ANAN:

105711209(MAP3K3)

CSYR:

103252889(MAP3K3)

MMUR:

105861627(MAP3K3)

LCAT:

123620590(MAP3K3)

PCOQ:

105824000(MAP3K3)

OGA:	100944704(MAP3K3)

MMU:	26406(Map3k3)

MCAL:

110305762(Map3k3)

MPAH:

110331495(Map3k3)

RNO:	303604(Map3k3)

MCOC:

116076740(Map3k3)

ANU:	117710722(Map3k3)

MUN:	110547048(Map3k3)

CGE:	100753508(Map3k3)

MAUA:

101832971(Map3k3)

PROB:

127218084(Map3k3)

PLEU:

114690404(Map3k3)

MORG:

121436150(Map3k3)

MFOT:

126514953

AAMP:

119812909(Map3k3)

NGI:	103744757(Map3k3)

HGL:	101704335(Map3k3)

CPOC:

100731994(Map3k3)

CCAN:

109703189(Map3k3)

DORD:

105998545(Map3k3)

DSP:	122103464(Map3k3)

PLOP:

125365123(Map3k3)

NCAR:

124979643

MMMA:

107158328(Map3k3)

OCU:

100355324

OPI:	101534751(MAP3K3)

TUP:	102477673(MAP3K3)

GVR:	103589229(MAP3K3)

CFA:	480481(MAP3K3)

CLUD:

112652993(MAP3K3)

VVP:	112920702(MAP3K3)

VLG:	121473381(MAP3K3)

NPO:	129511556(MAP3K3)

AML:	100475740(MAP3K3)

UMR:	103665628(MAP3K3)

UAH:	113265289(MAP3K3)

UAR:	123802932(MAP3K3)

ELK:

111158066

LLV:

125087832

MPUF:

101674882(MAP3K3)

MNP:	132004017(MAP3K3)

MLK:	131816910(MAP3K3)

NVS:	122906090(MAP3K3)

ORO:	101375291(MAP3K3)

EJU:	114196698(MAP3K3)

ZCA:	113939885(MAP3K3)

MLX:	118024385(MAP3K3)

NSU:	110570388(MAP3K3)

LWW:	102734394(MAP3K3)

FCA:	101083633(MAP3K3)

PYU:	121015257(MAP3K3)

PCOO:

112864457(MAP3K3)

PBG:	122485762(MAP3K3)

PVIV:

125151909(MAP3K3)

LRUF:

124513542

PTG:	102966576(MAP3K3)

PPAD:

109277107(MAP3K3)

PUC:

125926671

AJU:

106978686

HHV:	120234206(MAP3K3)

BTA:	508943(MAP3K3)

BOM:	102275307(MAP3K3)

BIU:	109573385(MAP3K3)

BBUB:

102413611(MAP3K3)

BBIS:

105000508(MAP3K3)

CHX:	102173036(MAP3K3)

OAS:	101122537(MAP3K3)

BTAX:

128064421(MAP3K3)

ODA:	120866946(MAP3K3)

CCAD:

122439701(MAP3K3)

MBEZ:

129544535(MAP3K3)

SSC:	100513491(MAP3K3)

CFR:	102505759(MAP3K3)

CBAI:

105069789(MAP3K3)

CDK:	105090412(MAP3K3)

VPC:	102540602(MAP3K3)

BACU:

102999255(MAP3K3)

BMUS:

118886567(MAP3K3)

LVE:	103076636(MAP3K3)

OOR:	101273961(MAP3K3)

DLE:	111182605(MAP3K3)

PCAD:

102985586(MAP3K3)

PSIU:

116745546(MAP3K3)

NASI:

112410489(MAP3K3)

ECB:	100064751(MAP3K3)

EPZ:	103549765(MAP3K3)

EAI:	106835525(MAP3K3)

MYB:	102242308(MAP3K3)

MYD:	102762787(MAP3K3)

MMYO:

118671605(MAP3K3)

MLF:	102442880(MAP3K3)

MDT:	132218565(MAP3K3)

PKL:	118726628(MAP3K3)

EFUS:

103293150(MAP3K3)

MNA:	107530487(MAP3K3)

DRO:	112316249(MAP3K3)

SHON:

119003525(MAP3K3)

AJM:	119036313(MAP3K3)

PDIC:

114502262(MAP3K3)

PHAS:

123816809(MAP3K3)

MMF:	118634916(MAP3K3)

PPAM:

129070196(MAP3K3)

HAI:	109380266(MAP3K3)

RFQ:	117013390(MAP3K3)

PALE:

102889570(MAP3K3)

PGIG:

120600282(MAP3K3)

PVP:	105297731(MAP3K3)

RAY:	107501901(MAP3K3)

MJV:	108401834(MAP3K3)

TOD:	119232633(MAP3K3)

SARA:

101555844(MAP3K3)

SETR:

126017334(MAP3K3)

LAV:	100662122(MAP3K3)

TMU:

101341472

ETF:	101657417(MAP3K3)

DNM:	101410864(MAP3K3)

MDO:	100025970(MAP3K3)

GAS:	123244863(MAP3K3)

SHR:	100933837(MAP3K3)

AFZ:

127560409

PCW:	110215942(MAP3K3)

TVP:	118848119(MAP3K3)

OAA:	100083301 100092024(MAP3K3)

GGA:	419954(MAP3K3) 420419(MAPKKK3L)

PCOC:

116233811(MAP3K3) 116238245

MGP:	100542691 100542719(MAP3K3)

CJO:	107308787 107325133(MAP3K3)

TPAI:

128087323 128088727(MAP3K3)

LMUT:

125684649(MAP3K3) 125695837

NMEL:

110388470(MAP3K3) 110394259

APLA:

101795869 101801284(MAP3K3)

ACYG:

106036842 106045975(MAP3K3)

CATA:

118251789 118258931(MAP3K3)

AFUL:

116486750 116498376(MAP3K3)

TGU:	100223633(MAP3K3) 100226503

LSR:	110474827(MAP3K3) 110484542

SCAN:

103812700 103821658(MAP3K3)

PMOA:

120498159(MAP3K3) 120510578

OTC:	121338070 121347567(MAP3K3)

PRUF:

121352471(MAP3K3) 121364634

GFR:	102032306(MAP3K3) 102044243

FAB:	101813992(MAP3K3) 101817004

OMA:	130249972 130264032(MAP3K3)

PHI:	102108460 102112033(MAP3K3)

PMAJ:

107200237 107215258(MAP3K3)

CCAE:

111925531 111939927(MAP3K3)

CCW:	104686414 104698629(MAP3K3)

CBRC:

103619882(MAP3K3) 103623939

ETL:	114065134 114066926(MAP3K3)

ZAB:	102061523(MAP3K3) 102068579

ZLE:	135443550 135458685(MAP3K3)

ACHL:

103802063(MAP3K3) 103803986

SVG:	106851598 106861195(MAP3K3)

MMEA:

130573170 130582463(MAP3K3)

HRT:	120752063 120763686(MAP3K3)

SATI:

136358095 136372313(MAP3K3)

FPG:	101912446(MAP3K3) 101923251

FCH:	102047801(MAP3K3) 102050351

CCRI:

104162271(MAP3K3) 104163806

NNT:	104402400 104409913(MAP3K3)

SHAB:

115609418 115617902(MAP3K3)

ACUN:

113477214 113489126(MAP3K3)

TALA:

104365343 104365963(MAP3K3)

ACHC:

115339806 115344350(MAP3K3)

HALD:

104318986(MAP3K3) 104320698

HLE:	104827837 104827981(MAP3K3)

AGEN:

126037884 126038723

GCL:	127013622 127026479

CSTI:

104550852 104562083(MAP3K3)

LDI:	104344381(MAP3K3) 104348091

MNB:	103777222 103778704(MAP3K3)

DPUB:

104298979 104309224(MAP3K3)

AVIT:

104270669 104278271(MAP3K3)

BRHI:

104491398(MAP3K3)

EGZ:	104130961 104134638(MAP3K3)

NNI:	104009891(MAP3K3) 104021753

PCRI:

104027555(MAP3K3) 104038607

PCAO:

104050582 104052496(MAP3K3)

PADL:

103913871(MAP3K3) 103924744

AFOR:

103896151 103906066(MAP3K3)

FGA:	104076924(MAP3K3) 104077842

GSTE:

104254231(MAP3K3) 104259046

CLV:	102085060(MAP3K3) 102088147

MUI:	104534481 104536722(MAP3K3)

PGUU:

104464009 104464263(MAP3K3)

PLET:

104621404 104624166(MAP3K3)

EHS:	104511998(MAP3K3) 104512258

CMAC:

104485993(MAP3K3) 104487253

CUCA:

104054378(MAP3K3) 104056977

TEO:	104379019 104384438(MAP3K3)

BREG:

104632129 104642142(MAP3K3)

OHA:	104337214 104338682(MAP3K3)

ACAR:

104518697 104525494(MAP3K3)

CPEA:

104396174 104398030(MAP3K3)

CVF:	104285380(MAP3K3) 104291263

RTD:	128905604 128919160(MAP3K3)

AAM:	106497426(MAP3K3)

AROW:

112962749(MAP3K3) 112969323

NPD:	112958101 112960230(MAP3K3)

TGT:	104573012(MAP3K3) 104578294

DNE:	112981158 112982786(MAP3K3)

SCAM:

104144774(MAP3K3) 104150762

ASN:	102368863 102374958(MAP3K3)

AMJ:	102572648 106736961(MAP3K3)

CPOO:

109306583 109319002(MAP3K3)

GGN:	109291200 109301682(MAP3K3)

PSS:	102454634(MAP3K3) 102454880

CMY:	102930570(MAP3K3) 102931859

CCAY:

125626662(MAP3K3) 125631186

DCC:	119849034(MAP3K3) 119851757

CPIC:

101948589 101953672(MAP3K3)

TST:	117869137(MAP3K3) 117871989

CABI:

116827890 116839493(MAP3K3)

MRV:	120392173(MAP3K3) 120398118

ACS:	100557698(map3k3) 100562159

ASAO:

132778403(MAP3K3) 132779008

PVT:	110080317(MAP3K3) 110085837

SUND:

121933419(MAP3K3) 121934750

PBI:	103064885 103066986(MAP3K3)

PMUR:

107284356 107302364(MAP3K3)

CTIG:

120302697(MAP3K3) 120313608

TSR:	106540521(MAP3K3) 106545629

PGUT:

117654825 117665021(MAP3K3)

APRI:

131197164(MAP3K3) 131197469

PTEX:

113447218(MAP3K3) 113447966

NSS:	113419489 113420074(MAP3K3)

VKO:	123020993 123031851(MAP3K3)

PMUA:

114581713(MAP3K3) 114607438

PRAF:

128399929(MAP3K3) 128424067

ZVI:	118091861 118094234(MAP3K3)

HCG:	128331714 128332060(MAP3K3)

GJA:

107116392

STOW:

125424924

EMC:

129337981

XLA:	108701764(map3k3.L) 108702560(map3k3.S) 108719812(map3k22.S) 734336(map3k22.L)

XTR:	100488360(map3k22) 100490021(map3k3)

NPR:	108784622 108802493(MAP3K3)

RTEM:

120919516(MAP3K3) 120940127

BBUF:

121002332 121003275(MAP3K3)

BGAR:

122937994 122941234(MAP3K3)

MUO:

115466611

GSH:

117354355

DRE:	100126011(map3k22) 560211(map3k3)

SRX:	107721962 107729565(map3k3) 107741004 107758305

SANH:

107658467 107670426 107674169 107701654

SGH:	107570753 107583042 107584944 107591272

CCAR:

109045414 109049848 109063690 109111830

CAUA:

113046030 113047227 113047236 113066300 113099578

CGIB:

127946604 127949489 127953641 128013156

PTET:

122329800(map3k22) 122341269(map3k3)

LROH:

127155446(map3k22) 127156602(map3k3)

OMC:	131532913(map3k22) 131537410(map3k3)

PPRM:

120476029(map3k22) 120489484(map3k3)

RKG:	130072813(map3k3) 130083830(map3k22)

MAMB:

125257583(map3k22) 125276864(map3k3)

CIDE:

127505843 127509155

CERY:

137013498(map3k22) 137017581(map3k3)

MASI:

127432062 127434782 127450601 127451349

TROS:

130547029(map3k22) 130561833(map3k3)

TDW:	130413365(map3k22) 130426448(map3k3)

MANU:

129425922(map3k22) 129436086(map3k3)

IPU:	108256020 108256334(map3k22)

IFU:	128599682(map3k22) 128602865(map3k3)

PHYP:

113528353(map3k3) 113541066

SMEO:

124375590(map3k22) 124397000(map3k3)

TFD:	113652189(map3k3) 113660144(map3k22)

TVC:	132839958(map3k22) 132861545(map3k3)

TRN:	134301254(map3k22) 134336003(map3k3)

AMEX:

103034596(map3k3) 103044968(map3k22)

CMAO:

118798602(map3k22) 118821192(map3k3)

EEE:	113580221(map3k3) 113581205

CHAR:

105890180(map3k22) 105898540(map3k3)

TRU:	101061953 101072543(map3k3)

TFS:	130514273(map3k22) 130515228(map3k3)

TNG:	GSTEN00023918G001 GSTEN00027814G001

LCO:	104930222(map3k3) 104937092

NCC:	104943590(map3k3)

TBEN:

117492676(map3k3) 117495604(map3k22)

CGOB:

115025332

PGEO:

117451111(map3k3) 117465533(map3k22)

GACU:

117535848(map3k22) 117548727(map3k3)

EMAC:

134878281(map3k3) 134884081(map3k22)

ELY:	117264776(map3k22) 117268573(map3k3)

EFO:	125878923(map3k3) 125881649(map3k22)

PLEP:

121956486(map3k3) 121960467(map3k22)

SLUC:

116037923(map3k22) 116063928(map3k3)

ECRA:

117937594(map3k22) 117958168(map3k3)

ESP:	116672482 116703027(map3k3)

PFLV:

114548980 114569844(map3k3)

GAT:	120811919(map3k22) 120827375(map3k3)

PPUG:

119198728(map3k22) 119220774(map3k3)

AFB:	129098437(map3k3) 129110801(map3k22)

CLUM:

117734588(map3k3) 117749675(map3k22)

PSWI:

130188944(map3k3) 130205998(map3k22)

MSAM:

119893582(map3k3) 119910267(map3k22)

SCHU:

122866647(map3k22) 122869128(map3k3)

CUD:	121527233(map3k22) 121529500(map3k3)

ALAT:

119008591(map3k22) 119014200(map3k3)

MZE:	101468082(map3k3) 101475626

ONL:	100692691(map3k3) 100711264

OAU:	116309274(map3k3) 116314455(map3k22)

OLA:	101156127 101169290(map3k3)

OML:	112145989(map3k3) 112151453(map3k22)

CSAI:

133421768(map3k3) 133423099(map3k22)

XMA:	102228349 102234853(map3k3)

XCO:	114136809 114160172(map3k3)

XHE:	116711766 116735892(map3k3)

PRET:

103456566 103468920(map3k3)

PFOR:

103140402 103144993(map3k3)

PLAI:

106948891 106960611(map3k3)

PMEI:

106905053(map3k3) 106921034

GAF:	122821891(map3k3) 122824584(map3k22)

PPRL:

129364707(map3k22) 129373989(map3k3)

CVG:	107084751(map3k3) 107100967

CTUL:

119783389(map3k3) 119788998(map3k22)

GMU:	124858048(map3k22) 124863354 124864760

NFU:	107378534(map3k3) 107382822

KMR:	108230337(map3k22) 108237722(map3k3)

ALIM:

106513381 106534689(map3k3)

NWH:	119421229(map3k3) 119426395(map3k22)

AOCE:

111565972 111588903(map3k3)

MCEP:

124995666(map3k22) 124998192(map3k3)

CSEM:

103392663(map3k3)

POV:	109629552 109629839 109633995(map3k3)

SSEN:

122770611(map3k22) 122784976(map3k3)

HHIP:

117753812(map3k22) 117766821(map3k3)

HSP:	118098509(map3k22) 118123588(map3k3)

PPLT:

128425805(map3k22) 128458263(map3k3)

SMAU:

118288598(map3k3) 118290920(map3k22)

LCF:	108880564 108881705(map3k22)

SDU:	111217593(map3k3) 111221016

SLAL:

111656266 111660589(map3k3)

XGL:	120785035(map3k3) 120789697(map3k22)

HCQ:	109519483 109532434(map3k3)

SSCV:

125983722 125986082

SBIA:

133492821(map3k22) 133514879(map3k3)

PEE:	133396365(map3k22) 133415214(map3k3)

PTAO:

133466645(map3k3) 133470061(map3k22)

BPEC:

110160986 110167886(map3k3)

MALB:

109961492 109963171(map3k3)

BSPL:

114853752(map3k22) 114860371(map3k3)

SJO:	128379177(map3k3) 128382685(map3k22)

SASA:

106590696 106595351(map3k3) 106606859

STRU:

115171523 115195304 115203817

OTW:	112227444(map3k22) 112259007 121847262

OMY:	110486686 110538641 118938953(map3k22)

OGO:	124000403(map3k3) 124000568 124039431(map3k22)

ONE:	115110787 115110791

OKI:	109878689 109881914 109882222

OKE:	118374908(map3k3) 118377367 118382476

SALP:

111980991(map3k3) 112077065

SNH:	120034406 120044068

CCLU:

121549640 121556447 121568899 123482471 123491196

ELS:	105007693 105012974(map3k3)

SFM:	108918963 108927989 108937422

PKI:	111837634 111837851 111849744 111852859

AANG:

118220927(map3k3) 118225399(map3k22) 118233621

LOC:	102684228(map3k3) 102684734

PSPA:

121301869(map3k3) 121309866 121314031 121324895

ARUT:

117394816(map3k22) 117400396 117416421 117435074

PSEX:

120517514(map3k3) 120529593(map3k22)

LCM:	102350357 102353974(MAP3K3)

CMK:	103187711(map3k3) 103189852(map3k22)

RTP:	109913314(map3k22)

CPLA:

122540043(map3k3) 122548923(map3k22)

HOC:	132815069(map3k22) 132831031(map3k3)

LERI:

129710233(map3k3) 129715132

PMRN:

116948608

LRJ:

133349757

NAI:	NECAME_10109

BGT:	106072482 106080307

GAE:

MMER:

RPHI:

MAEA:

LJP:

ATEN:

XEN:

HMG:

HSY:

RES:	135681172 135692543

ATH:	AT1G53570(MAP3KA)

ALY:

9330509

CRB:

17898011

CSAT:

104742876 104758708 104778292

EUS:	EUTSA_v10022608mg

BRP:

103860382

BNA:	106389401 106439753

BOE:

106335806

RSZ:

108863113

THJ:	104807156 104819497

CPAP:

110816131 110818034

CIT:

102607672

CIC:	CICLE_v10000585mg

PVY:

116121481

MINC:

123199320

TCC:	18592500 18611858

GRA:	105762573 105779946 105797098

GHI:	107910418 107930871 107931203 107952027 107959477 107959605

GAB:	108458775 108475630 108476628

HSYR:

120118570 120131078 120146496 120147698 120165575 120199978

DZI:

111299762

EGR:

104415891

GMX:	100780004 100780263 100787064 100813122

GSJ:	114410093 114413225 114415780 114422014

PVU:	PHAVU_002G272100g PHAVU_009G150500g

VRA:	106773523 106780713

VAR:	108320414 108331635

VUN:	114162599 114177783

VUM:	124836865 124847476

CCAJ:

109799423 109807768

APRC:

113853597 113863686

MTR:	11425554 11436239

TPRA:

123913372 123914045

CAM:	101490408 101514482

PSAT:

127079711 127105135

VVO:	131602860 131638432 131661116

LJA:	130711957 130712915

ADU:

107480227

AIP:

107630938

AHF:	112715925 112733082 112782275 112791116

LANG:

109326749 109337627 109343408 109361470

PCIN:

129302601 129320293

QSA:	O6P43_030333

FVE:

RCN:

PPER:

PMUM:

PAVI:

PDUL:

MDM:	103422673 103427113

MSYL:

126589008 126617425

PXB:	103938937 103960739

ZJU:

MNT:

CSAV:

CSV:

CMO:

BHJ:

MCHA:

CMAX:

CMOS:

CPEP:

RCU:

MEAN:

JCU:	105629174 105629578

HBR:	110651202 110661413 110662262

MESC:

110609539 110628225 110629945

POP:	7466732 7479138

PEU:	105124578 105130405

PALZ:

118032466 118040154

JRE:	108996281 109008901 109008902

CILL:

122303394 122307221

CAVE:

132165456

QSU:	111984336 111994181

QLO:	115959255 115963246

TWL:	120001739 120016845

VVI:

100243772

VRI:

117913566

SLY:	101243985 543918(MAPKKKalpha)

SPEN:

107004855 107018254

SOT:	102578443 107062289

SSTN:

125844997 125850530

SDUL:

129900703 129904227

CANN:

107850668 107867737

LBB:	132614984 132627225

NTA:	107760154 107765447 107799389 107821703

NSY:	104216818 104226881

NTO:	104116350 104116515

NAU:	109210228 109227015

INI:	109157540 109172719

ITR:	116012813 116013394 116021148

SIND:

105178081

OEU:	111367816 111397927 111401121 111410383

EGT:	105950093 105972633 105973230

SSPL:

SMIL:

SHIS:

APAN:

HAN:	110908419 110910535

ECAD:

122601950

LSV:	111880005 111894232

CCAV:

112511697

DCR:

108204080

CSIN:

114282277

RVL:	131303830 131335057

AEW:	130778269 130781230

BVG:

104895397

SOE:	110775554 110784504

CQI:	110681971 110695137

ATRI:

130820731 130823139

MOF:	131155902 131161911

NNU:	104599577 104606749

MING:

122071831 122074472

TSS:	122667763 122669323

OSA:	4329659 4335914 4350033

OBR:	102700618 102709411 102721244

OGL:	127754612 127763775 127772161

BDI:	100828104 100844114 100846068

ATS:	109750728 109758282

TDC:	119286437 119295336 119355208 119361473 119364336

TAES:

123042751 123045513 123053363 123086616 123091367 123096336 123189268 123191050

TUA:	125538344 125538475 125550885

LPER:

127294119 127334499 127334915

LRD:	124672819 124673793 124690139 124692386 124703553 124703555

SBI:	110435646 8064268 8075833

ZMA:	100191147 100191795 103627282

MFLO:

136467142 136473956 136483788 136483804 136486698 136486785 136490600

SITA:

101772243 101773692 101774927

SVS:	117833052 117856081 117863774

PVIR:

120641043 120644201 120656063 120668009 120681552 120684394 120699953 120704611

PHAI:

112886386 112895053 112899426 112902460

PDA:	103711039 103720517

EGU:	105038493 105051751

MUS:	103988068 103989096 103997449

ZOF:	121967995 121981534 121985411 122002657 122006906 122026600

DCT:	110098287 110112062

PEQ:	110021280 110024668

AOF:

MSIN:

NCOL:

ATR:

SMO:	SELMODRAFT_144969(MAP3KA3-1)

CME:	CYME_CMT185C

SLA:	SERLADRAFT_398861

SRE:	PTSG_00201 PTSG_13011

PTM:	GSPATT00015783001

GTT:	GUITHDRAFT_151185

» show all

Reference

PMID:18855897

Authors

Craig EA, Stevens MV, Vaillancourt RR, Camenisch TD

Title

MAP3Ks as central regulators of cell fate during development.

Journal

Dev Dyn 237:3102-14 (2008)
DOI:10.1002/dvdy.21750

Reference

PMID:9006902

Authors

Ellinger-Ziegelbauer H, Brown K, Kelly K, Siebenlist U

Title

Direct activation of the stress-activated protein kinase (SAPK) and extracellular signal-regulated protein kinase (ERK) pathways by an inducible mitogen-activated protein Kinase/ERK kinase kinase 3 (MEKK) derivative.

Journal

J Biol Chem 272:2668-74 (1997)
DOI:10.1074/jbc.272.5.2668

Sequence

[hsa:4215]

LinkDB

DBGET integrated database retrieval system