Bison bison bison (American bison): 105003655 Help Entry 105003655         CDS       T08726                                  Symbol CASP8 Name (RefSeq) caspase-8   KO K04398   caspase 8 [EC:3.4.22.61] Organism bbis  Bison bison bison (American bison) Pathway bbis01524   Platinum drug resistance bbis04115   p53 signaling pathway bbis04210   Apoptosis bbis04215   Apoptosis - multiple species bbis04217   Necroptosis bbis04620   Toll-like receptor signaling pathway bbis04621   NOD-like receptor signaling pathway bbis04622   RIG-I-like receptor signaling pathway bbis04623   Cytosolic DNA-sensing pathway bbis04625   C-type lectin receptor signaling pathway bbis04657   IL-17 signaling pathway bbis04668   TNF signaling pathway bbis04932   Non-alcoholic fatty liver disease bbis04936   Alcoholic liver disease bbis05010   Alzheimer disease bbis05016   Huntington disease bbis05022   Pathways of neurodegeneration - multiple diseases bbis05132   Salmonella infection bbis05134   Legionellosis bbis05142   Chagas disease bbis05145   Toxoplasmosis bbis05152   Tuberculosis bbis05160   Hepatitis C bbis05161   Hepatitis B bbis05162   Measles bbis05163   Human cytomegalovirus infection bbis05164   Influenza A bbis05165   Human papillomavirus infection bbis05167   Kaposi sarcoma-associated herpesvirus infection bbis05168   Herpes simplex virus 1 infection bbis05169   Epstein-Barr virus infection bbis05170   Human immunodeficiency virus 1 infection bbis05200   Pathways in cancer bbis05203   Viral carcinogenesis bbis05416   Viral myocarditis bbis05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:bbis00001]  09130 Environmental Information Processing   09132 Signal transduction    04668 TNF signaling pathway     105003655 (CASP8)  09140 Cellular Processes   09143 Cell growth and death    04210 Apoptosis     105003655 (CASP8)    04215 Apoptosis - multiple species     105003655 (CASP8)    04217 Necroptosis     105003655 (CASP8)    04115 p53 signaling pathway     105003655 (CASP8)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     105003655 (CASP8)    04621 NOD-like receptor signaling pathway     105003655 (CASP8)    04622 RIG-I-like receptor signaling pathway     105003655 (CASP8)    04623 Cytosolic DNA-sensing pathway     105003655 (CASP8)    04625 C-type lectin receptor signaling pathway     105003655 (CASP8)    04657 IL-17 signaling pathway     105003655 (CASP8)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     105003655 (CASP8)    05203 Viral carcinogenesis     105003655 (CASP8)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     105003655 (CASP8)    05161 Hepatitis B     105003655 (CASP8)    05160 Hepatitis C     105003655 (CASP8)    05164 Influenza A     105003655 (CASP8)    05162 Measles     105003655 (CASP8)    05168 Herpes simplex virus 1 infection     105003655 (CASP8)    05163 Human cytomegalovirus infection     105003655 (CASP8)    05167 Kaposi sarcoma-associated herpesvirus infection     105003655 (CASP8)    05169 Epstein-Barr virus infection     105003655 (CASP8)    05165 Human papillomavirus infection     105003655 (CASP8)   09171 Infectious disease: bacterial    05132 Salmonella infection     105003655 (CASP8)    05134 Legionellosis     105003655 (CASP8)    05152 Tuberculosis     105003655 (CASP8)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     105003655 (CASP8)    05142 Chagas disease     105003655 (CASP8)   09164 Neurodegenerative disease    05010 Alzheimer disease     105003655 (CASP8)    05016 Huntington disease     105003655 (CASP8)    05022 Pathways of neurodegeneration - multiple diseases     105003655 (CASP8)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     105003655 (CASP8)    05416 Viral myocarditis     105003655 (CASP8)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     105003655 (CASP8)    04932 Non-alcoholic fatty liver disease     105003655 (CASP8)   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     105003655 (CASP8)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:bbis01002]     105003655 (CASP8) Enzymes [BR:bbis01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.61  caspase-8      105003655 (CASP8) Peptidases and inhibitors [BR:bbis01002]  Cysteine peptidases   Family C14: caspase family    105003655 (CASP8) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Peptidase_C14 DED PYRIN Motif Other DBs NCBI-GeneID:  105003655 NCBI-ProteinID:  XP_010859268 Ensembl:  ENSBBBG00000012853 UniProt:  A0A6P3IY78 LinkDB All DBs Position Unknown AA seq 485 aa AA seqDB search MALTQCLYNIGEQLGSDDLAALKFLSRDHIPYRKQEPIKDALMLFQRLQEKRMLEENNLS FLKELLFRVNRLDLLLNYLYTSEEEMKRELQIPGRAQISAYRILLFQISEDVNKVELKDF KFFLSQEIAKCKLDDDMTLLDIFVEMEKRTILGEENLDTLKRICEQVNKSLLKKIYDYEE LRKERRMSLERDPYAFSNDMSQSLPEEGYSKMPAMSDSPEQDSELQTSDTVYRMTSKPRG YCLIFNNYDFSIARKQVPELHDLKDRTGTDFDADALDKTFRELHFEIVHYKDQTAKGICE VLESYQKKDHKNKDCFICCILTHGNKGIIYGSDGQEASIYELTSYFTGLKCPSLIGKPKI FFIQACQGDKYQKGVAVETDSEQMEAYLEVDSSPQKRYIPDEADFLLGMATVKNYVSYRN IWNGAWYIQSLCQNLRERCPRGEDILTILTNVNFEVSKLDDKQRMAKQMPQPTFTLRKKL FFPLN NT seq 1458 nt NT seq  +upstreamnt  +downstreamnt atggcgctcacccaatgtctctataatattggggagcagctgggcagtgacgacctggct gccctcaagttcctaagccgggaccacatcccatataggaagcaggaacccatcaaggat gccttgatgctattccagaggctccaagaaaagagaatgttggaggaaaacaatctgtcc ttcttgaaggagctgcttttccgagtgaatagactggatctgctgcttaactacttgtat accagcgaggaggagatgaagagggagcttcagatacccggcagggcccagatctctgcc tacaggattctgcttttccagatttcagaagatgtgaacaaagtagaattgaaggacttt aagttttttttgagccaggagattgccaaatgtaagctggatgatgacatgactttgctt gatattttcgtggagatggagaagaggaccatcctaggggaagagaacttggacaccctg aaaagaatctgtgagcaggtcaacaagagcttgctgaagaaaatctatgattatgaagaa ttaagaaaagagagaagaatgagccttgaaagagacccatatgcattttcaaatgatatg tcacaatcgcttccagaggagggctactctaagatgccggccatgtcagactctccagaa caggacagtgagttgcagacatctgacacagtttaccgaatgacaagcaaacctcgggga tactgtttgatctttaacaattatgattttagcatagcacggaagcaggtgcctgaactt cacgaccttaaggataggactggaacagactttgatgcagacgctttggataagaccttt cgtgaacttcattttgagatagtgcactacaaagaccaaacagcaaagggaatctgtgag gttctagaatcctaccagaagaaggaccacaaaaacaaagactgcttcatctgctgcatc ctcacccacggaaacaagggcatcatctatggctccgatgggcaagaagcctccatctat gagctgacctcttacttcactggcttaaaatgcccttcccttattggcaaacccaaaatc ttttttattcaggcttgccaaggggacaagtaccagaaaggtgtagccgttgagaccgac tcagaacagatggaagcctatttagaggtggactcatcacctcagaagagatatatccca gatgaggctgactttctgctggggatggccactgtgaaaaactatgtttcctaccgaaac atctggaatggggcctggtatatccaatcactttgccagaatctgagagaaagatgtcct aggggtgaagacattctgaccatcctaaccaacgtgaacttcgaagtaagcaaactggat gacaagcaacgtatggccaaacagatgccacaacctactttcacactgcgaaaaaaactc ttctttcctcttaattga

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