Bubalus bubalis (water buffalo): 102390921
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Entry
102390921 CDS
T05912
Symbol
ITCH
Name
(RefSeq) E3 ubiquitin-protein ligase Itchy homolog isoform X1
KO
K05632
E3 ubiquitin-protein ligase Itchy [EC:
2.3.2.26
]
Organism
bbub
Bubalus bubalis (water buffalo)
Pathway
bbub04120
Ubiquitin mediated proteolysis
bbub04144
Endocytosis
bbub04330
Notch signaling pathway
bbub04668
TNF signaling pathway
bbub04932
Non-alcoholic fatty liver disease
Brite
KEGG Orthology (KO) [BR:
bbub00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
102390921 (ITCH)
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
102390921 (ITCH)
04668 TNF signaling pathway
102390921 (ITCH)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
102390921 (ITCH)
09160 Human Diseases
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
102390921 (ITCH)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
bbub04131
]
102390921 (ITCH)
04121 Ubiquitin system [BR:
bbub04121
]
102390921 (ITCH)
Enzymes [BR:
bbub01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
102390921 (ITCH)
Membrane trafficking [BR:
bbub04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
102390921 (ITCH)
Ubiquitin system [BR:
bbub04121
]
Ubiquitin ligases (E3)
HECT type E3
102390921 (ITCH)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HECT
WW
C2
Motif
Other DBs
NCBI-GeneID:
102390921
NCBI-ProteinID:
XP_045018557
LinkDB
All DBs
Position
14:complement(19781445..19880454)
Genome browser
AA seq
862 aa
AA seq
DB search
MSDSGSQLGSMGSLTMKSQLQITVISAKLKENKKNWFGPSPYVEVTVDGQSKKTEKCNNT
NSPKWKQPLTVIVTPVSKLHFRVWSHQTLKSDVLLGTAGLDIYETLKSNNMKLEEVVVTL
QLVGDKEPAETIGDLSVCLDGLQLESEVVANGETTCSESASQNDDGSRPKDETRANASGS
DDPEDTGSGENRRINGNNSPSLSNGGFKPSRPPRPSRPPPPTPRRPASVNGSPSTTSESD
GSSTGSLPPTNTNSSTSEGAASGLIIPLTISGGAGPRPLNPVPQAPLPPGWEQRVDQHGR
VYYVDHIEKRTTWDRPEPLPPGWERRVDNMGRIYYVDHFTRTTTWQRPTLESVRNYEQWQ
LQRSQLQGAMQQFNQRFIYGNQDLFATSQNKEFDPLGPLPPGWEKRTDSNGRVYFVNHNT
RITQWEDPRNQGQLNEKPLPEGWEMRFTVDGIPYFVDHNRRTTTYIDPRTGKSALDNGPQ
IAYVRDFKAKVQYFRFWCQQLAMPQHIKITVTRKTLFEDSFQQIMSFSPQDLRRRLWVIF
PGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFRFI
GRFIAMALFHGKFIDTGFSLPFYKRILNKPVGLKDLESIDPEFYNSLIWVKENNIEECGL
EMYFSVDKEILGEIKSHDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGF
NEILPQQYLQYFDAKELEVLLCGMQEIDLNDWQRHAIYRHYTRTSKQIMWFWQFVKEIDN
EKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEKVGKENWLPRSHTCFNRLDLPPYK
SYEQLKEKLLFAIEETEGFGQE
NT seq
2589 nt
NT seq
+upstream
nt +downstream
nt
atgtctgacagtggatcacagcttggttcaatgggtagtttgaccatgaaatcacaactt
cagatcactgtcatttcagcaaaacttaaagaaaataaaaagaattggtttgggccaagt
ccttatgtggaagtcacagtagatggacagtcaaagaagacagaaaaatgcaacaatacg
aacagtcccaaatggaagcagcctcttacagttattgtcacccctgtgagtaaattacat
tttcgtgtgtggagtcaccagacactgaaatctgatgttttgttgggaactgctggattg
gatatctatgaaacattaaagtcaaacaatatgaaacttgaggaagtagttgtgacttta
cagcttgtaggtgacaaagaaccagcagagacaataggagatttgtcagtctgtcttgat
gggctgcaactagagtctgaagttgttgccaatggtgaaactacatgttcagaaagtgct
tcacagaatgatgatggctccaggcccaaggatgaaacaagagcaaacgcaagtggatca
gatgaccctgaggatacagggtctggtgaaaataggaggatcaatgggaataattctcca
tcactctcaaatggcggttttaaaccttctaggcctccaagaccttcacgaccacctcca
cctaccccccgtagaccagcatctgtcaatggctcaccatctaccacttctgaaagtgat
ggctctagcacaggctctctgccaccaacgaatacaaattcaagtacatctgaaggagca
gcatctggattaatcattcctcttactatatctggaggtgcaggccctagaccattaaat
cctgtacctcaagctcccctcccacctggctgggagcagagagtggaccagcatgggcga
gtttactatgtagatcatattgaaaaaagaacaacgtgggatagaccagaacctctacct
cctggctgggagcggcgggttgacaacatgggacgtatttattatgttgaccatttcaca
agaacaacaacgtggcagaggccaacactggaatcagtccggaactatgaacaatggcag
ctccagcgtagtcaacttcagggagctatgcagcagtttaaccagaggttcatttatggg
aatcaagatttgtttgctacatcacaaaataaagaatttgatcccctgggtcccctgccg
cctggatgggagaagagaacggacagcaatggtagagtatattttgtcaaccacaacact
cgtattacacaatgggaagaccccagaaatcaaggtcaattaaatgaaaagcccttacct
gaaggctgggaaatgagattcacggtagacggaattccgtattttgtggaccacaataga
agaacaaccacctatatagatccccgcaccggaaaatctgccttagacaatggaccccag
atagcctatgtacgggacttcaaggcaaaggttcaatatttccgtttctggtgtcagcaa
ctggccatgccacagcacataaagattacagtgacaagaaaaacattgtttgaggattcc
tttcagcagataatgagcttcagtcctcaagatctgcgaagacgtttgtgggtgattttt
ccaggagaagaaggtttagattatggaggtgtagcaagagaatggttctttcttttgtca
catgaggtgttgaacccaatgtattgcctgtttgaatatgcagggaaggataactactgc
ttgcagataaaccccgcttcttacatcaatccagatcacctgaaatattttcgttttatt
ggcaggtttattgctatggctctgttccatgggaaattcatagacacaggtttttctttg
ccattctataagcgtatcttgaataaaccagttggactgaaggatttagaatcgattgat
ccagaattttacaattctctcatctgggttaaagaaaacaatattgaggagtgtggtttg
gaaatgtatttctccgttgataaagaaatcttaggtgaaatcaagagtcatgatttgaaa
cccaatggtggcaatattcttgtaacagaagaaaataaagaggaatatatcagaatggta
gctgaatggagattgtctcgtggtgttgaagaacagacgcaagctttctttgagggcttt
aatgaaattcttccccagcagtatttacagtacttcgacgcaaaggaattagaggttctt
ttatgtgggatgcaagagattgatttgaatgattggcaaagacatgccatctaccgtcac
tataccaggacaagtaaacaaatcatgtggttttggcagtttgttaaagaaatcgataat
gagaagagaatgcgacttttgcagtttgttactgggacctgccgactgccagttggagga
tttgctgacctcatggggagcaatgggccacagaagttctgcattgaaaaagtcgggaaa
gaaaattggttgcctagaagtcatacctgttttaaccgcctggacctgccaccctacaag
agctatgagcaactgaaggaaaagctgttatttgctattgaagaaacagaaggctttgga
caagagtga
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