Bubalus bubalis (water buffalo): 102400549
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Entry
102400549 CDS
T05912
Symbol
ERBB4
Name
(RefSeq) receptor tyrosine-protein kinase ErbB-4 isoform X5
KO
K05085
receptor tyrosine-protein kinase erbB-4 [EC:
2.7.10.1
]
Organism
bbub
Bubalus bubalis (water buffalo)
Pathway
bbub04010
MAPK signaling pathway
bbub04012
ErbB signaling pathway
bbub04020
Calcium signaling pathway
bbub04151
PI3K-Akt signaling pathway
bbub05014
Amyotrophic lateral sclerosis
bbub05205
Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:
bbub00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
102400549 (ERBB4)
04012 ErbB signaling pathway
102400549 (ERBB4)
04020 Calcium signaling pathway
102400549 (ERBB4)
04151 PI3K-Akt signaling pathway
102400549 (ERBB4)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
102400549 (ERBB4)
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
102400549 (ERBB4)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
bbub01001
]
102400549 (ERBB4)
Enzymes [BR:
bbub01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
102400549 (ERBB4)
Protein kinases [BR:
bbub01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
102400549 (ERBB4)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Pkinase
Furin-like
TM_ErbB1
Kinase-like
Haspin_kinase
DUF4318
ABC1
Motif
Other DBs
NCBI-GeneID:
102400549
NCBI-ProteinID:
XP_045020521
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All DBs
Position
2:complement(151496963..152776169)
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AA seq
1292 aa
AA seq
DB search
MKLATGLWVWVSLLLAAGTVQPSSSQSVCAGTENKLSSLSDLEQQYRALRKYYENCEVVM
GNLEITSIEHNRDLSFLRSIREVTGYVLVALNQFRYLPLENLRIIRGTKLYEDRYALAIF
LNYRKDGNFGLQELGLKNLTEILNGGVYVDQNKFLCYTDTIHWQDIVRNPWPSNLTLVST
NGSSGCGRCHKSCTGRCWGPTENHCQTLTRTVCAEQCDGRCYGPYVSDCCHRECAGGCSG
PKDTDCFACMNFNDSGACVTQCPQTFVYNPTTFQLEHNFNAKYTYGAFCVKKCPHNFVVD
SSSCVRACPSSKMEVEENGIKMCKPCTDICPKACDGIGTGSLMSAQTVDSSNIDKFINCT
KINGNLIFLVTGIHGDPYNAIEAIDPEKLNVFRTVREITGFLNIQSWPPNMTDFSVFSNL
VTIGGRVLYSGLSLLILKQQGITSLQFQSLKEISAGNIYITDNSNLCYYHTVNWTTLFST
GNQRIVIRDNRKAENCTAEGMVCNHLCSNDGCWGPGPDQCLSCRRFSRGRTCIESCNLYD
GEFREFENGSICVECDPQCEKMEDGILTCHGPGPDNCTKCSHFKDGPNCVEKCPDGLQGA
NSFIFKYADQDRECHPCHPNCTQGCSGPTSHDCIYYLWTGHSTLPQHARTPLIAAGVIGG
LFILVIVGLTFAVYARRKSIKKKRALRRFLETELVEPLTPSGTAPNQAQLRILKETELKR
VKVLGSGAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKANVEFMDEALIMASMDHPHL
VRLLGVCLSPTIQLVTQLMPHGCLLDYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLV
HRDLAARNVLVKSPNHVKITDFGLARLLEGDEKEYNADGGKMPIKWMALECIHYRKFTHQ
SDVWSYGVTIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMID
ADSRPKFKELAAEFSRMARDPQRYLVIQGDDRMKLPSPNDSKFFQNLLDEEDLEDMMDAE
EYLVPQAFNIPPPIYTSRSRIDSNRNQFVYRDGGFAAEQGVPMPYRATTSTIPEAPIAQG
ATAEIFDDSCCNGTLRKSMAPHVQEDSSTQRYSADPTVFAPERSPRGELDEEGYMTPMRD
KPKQEYLNPVEENPFVSRRKNGDLQALDNPEYHSASSGPPKAEDEYVNEPLYLNTFANAL
GNAEYLKNSVLSVPEKAKKAFDNPDYWNHSLPPRSTLQHPDYLQEYSTKYFYKQNGRIRP
IVAENPEYLSEFSLKPGTVLPPPPYRHRNTVV
NT seq
3879 nt
NT seq
+upstream
nt +downstream
nt
atgaagctggcgacaggactgtgggtctgggtgagccttctcctggcggcggggaccgtc
cagcccagctcttctcagtcagtgtgtgcaggcacagagaataagctgagctctctctct
gacctggagcagcagtaccgagccttgcgcaaatactatgagaactgtgaggtagtcatg
ggcaacctggagataaccagcatcgagcacaaccgggacctctcctttctgcggtctata
cgagaagtcacaggctacgtgttggtggctcttaatcagtttcgctatctgcctctggag
aacttacgcattatccgtgggacaaagctttatgaggatcgatatgccttggcaatattt
ttaaactacagaaaagatggaaactttggacttcaagaacttggactgaagaacttgact
gaaatcctaaatggcggcgtctatgtagaccagaacaaatttctttgttatacagacact
attcattggcaagatattgttcggaatccatggccttccaacctgaccctggtgtcaaca
aatggtagctcaggatgcggacgttgccataagtcctgtactggccgatgctggggaccc
acagagaatcattgccagactttgacaaggaccgtgtgtgcggaacagtgtgatggcaga
tgctatggaccctacgtgagtgattgctgtcaccgagaatgtgctgggggctgttcggga
ccgaaggacaccgactgctttgcatgcatgaatttcaatgacagtggagcatgtgttact
cagtgtccacaaacatttgtctacaatcccactacctttcaactggagcataacttcaat
gcaaaatacacctatggagccttttgtgtcaagaagtgcccacataactttgtagttgat
tccagttcctgtgtgcgtgcttgtcctagttccaagatggaagtagaagaaaatgggatt
aaaatgtgtaaaccttgcactgacatttgcccaaaagcttgtgatggcattggcacagga
tcgttgatgtcagctcagaccgtggattccagtaacattgacaaattcataaactgcacc
aaaatcaatgggaatttgatcttccttgtcactggtattcatggggacccttacaatgca
attgaagccatagacccagagaaactgaatgtctttcggacagtccgagagataacaggt
ttcttgaacatacagtcatggcctccaaacatgaccgacttcagtgttttttctaacttg
gtaaccattggtggaagagtactctatagtggcctttccttgcttatcctcaagcaacag
ggcatcacttctctacaattccaatccttgaaagaaatcagtgcggggaacatctatatc
actgacaacagcaacctgtgctattatcacaccgttaactggacaacactgttcagcaca
ggcaaccaaaggatagtgattcgggacaataggaaagctgaaaactgtactgctgaagga
atggtgtgcaaccatctctgttcaaatgatgggtgttggggacctgggccagaccagtgc
ttgtcatgccgtcgcttcagcaggggaaggacctgcatagagtcttgtaacctctatgac
ggtgaatttcgggagtttgagaatggctccatctgtgtcgagtgtgacccccagtgtgag
aagatggaagatggcatcctcacatgccatgggccgggacctgacaactgtacaaagtgc
tcccatttcaaggatggcccaaactgtgtggaaaaatgtccagatggcttacagggggca
aacagtttcattttcaagtatgctgatcaagatcgagagtgccacccgtgccatccaaac
tgcacccaagggtgtagcggccccactagtcatgactgcatttactacctttggacgggc
cattccactttaccacaacatgctaggactcctctaattgcagctggagtcattggtggg
ctcttcatcctggtcattgtgggcctaacatttgcagtttatgctcgaaggaagagcatc
aaaaagaaaagagccttaagaagattcttggaaacagagctggtagaacccttaactccc
agtggcacagcgcccaatcaagctcaacttcgtattttgaaagaaactgagctcaaaaga
gtgaaagtacttggctcaggtgcttttggaactgtctataaaggtatttgggtccctgaa
ggagaaacagtgaagattcctgtggctattaagattcttaatgaaacaactggtcccaaa
gccaatgtggaatttatggatgaagccctaatcatggcaagtatggaccatccacactta
gttcgattattgggtgtgtgtctgagcccaaccattcagctggttacacagctcatgccc
catggctgtctgctggattatgtccatgaacacaaggataacattggatcacagttgttg
cttaactggtgtgtccagatagctaagggaatgatgtacctggaagaaagacggcttgtt
catcgggacttggcagcccgtaatgtcttagtgaaatctccaaaccatgtgaaaatcacg
gattttggactagccagactcttggaaggagatgaaaaagagtataatgctgatggagga
aagatgccaattaaatggatggctctggagtgtatacattataggaaattcacccatcag
agcgacgtttggagctatggagtcactatatgggaactgatgacctttggaggaaaacct
tatgatggaattccaaccagagaaattcctgatttattagagaaaggagaacgtttgcct
cagcctcccatctgcactattgacgtttacatggtcatggtcaaatgttggatgattgat
gctgacagtagacctaaatttaaggaactggctgctgaattttcaaggatggctcgagac
cctcaaagatacctagttattcagggtgatgatcgtatgaagcttcccagtccaaatgac
agcaagttctttcagaatctcttggatgaagaagatttagaagatatgatggatgctgag
gaatacctggtacctcaagctttcaacatccctcctcccatctatacttccagatcaaga
attgactcaaataggaaccagtttgtctaccgagacgggggcttcgctgcagaacaagga
gtgcccatgccctacagggccaccaccagcacaatcccagaagcccccattgctcagggg
gctaccgcagagatttttgatgactcctgctgtaatggcaccttacgcaagtccatggcg
ccccacgtccaagaggacagtagcacccagagatacagcgctgaccccacagtgtttgcc
ccagaacggagcccacgaggagagctggatgaagaaggttacatgactcctatgcgagac
aaacccaaacaagaatacctgaaccctgtggaggagaaccctttcgtttctcggaggaaa
aatggagaccttcaggctttggataatcccgaatatcacagcgcttccagtggtccaccc
aaggcagaagatgagtatgtaaacgagccgctgtacctcaacacctttgccaacgccttg
gggaacgccgagtacctgaagaacagcgtactgtctgtgccagagaaggccaagaaagca
ttcgacaaccccgactactggaaccacagcctgccacctcggagcacccttcagcaccca
gactacctgcaggagtacagcacaaaatatttttataaacaaaatggacggatccggcct
attgtggccgagaatcccgaatacctctctgagttctcgctgaagccaggcactgtgctg
cctccgccgccctacagacaccggaatactgtggtgtga
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