Bubalus bubalis (water buffalo): 102400736
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Entry
102400736 CDS
T05912
Symbol
BACE2
Name
(RefSeq) beta-secretase 2
KO
K07747
beta-site APP-cleaving enzyme 2 (memapsin 1) [EC:
3.4.23.45
]
Organism
bbub
Bubalus bubalis (water buffalo)
Pathway
bbub05010
Alzheimer disease
Brite
KEGG Orthology (KO) [BR:
bbub00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
102400736 (BACE2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
bbub01002
]
102400736 (BACE2)
Enzymes [BR:
bbub01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.23 Aspartic endopeptidases
3.4.23.45 memapsin 1
102400736 (BACE2)
Peptidases and inhibitors [BR:
bbub01002
]
Aspartic peptidases
Family A1: pepsin family
102400736 (BACE2)
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GFIT
Motif
Pfam:
Asp
TAXi_C
TAXi_N
Motif
Other DBs
NCBI-GeneID:
102400736
NCBI-ProteinID:
XP_025147917
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Position
1:186211314..186318847
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AA seq
514 aa
AA seq
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MGALARALLLPLLAQWLLRAAPALASAPFTLPLRVASATSRGAVPTPGPGPPAEPRADGL
ALALEPAGGAANFLAMVDNLQGDSGRGYYLEMQIGTPPQKLQILVDTGSSNFAVAGAPHP
YIDSYFDADRSSTYRPKGFDVTVKYTQGSWTGFVGEDVVTIPKGFNSSFLVNIATIFESE
NFFLPGIRWNGILGLAYATLAKPSSSLETFFDSLVAQAKIPNIFSMQMCGAGLPVAGSGT
NGGSLVLGGIEPTLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKAIVDS
GTTLLRLPQKVFDAVVEAVARTSLIPEFSEGFWTGSQLACWTNSETPWSYFPKISIYLRD
ENSSRSFRITILPQLYIQPMMGAGLNYECYRFGISPSTNALVIGATVMEGFYVVFDRARK
RVGFAASPCAEIAGAPVSEISGPFSTEDIASNCVPALPLNEPILWIVSYTLMSVCGVILL
VLITLLLLPVRCRHHPRDPEVVNDESSLVRHRWK
NT seq
1545 nt
NT seq
+upstream
nt +downstream
nt
atgggcgcgctggcccgggcgctgctgctgccgctgctggctcagtggctcctacgagcg
gccccggcgctggcctccgcgcccttcacgctgcctctccgggtggcctcggccacgagc
cggggggctgtgcctaccccggggcccggaccccccgctgagccccgcgcggacggcctg
gcgctcgccctggagcccgctgggggtgcggccaacttcttggccatggtggataacctg
cagggggactccggccgcggctactacctggagatgcaaatcgggacccccccgcagaag
ctgcagatactcgttgacaccggaagcagcaactttgccgtggccggggccccacatccc
tatatcgactcttactttgacgcagataggtccagcacgtaccgccccaagggttttgat
gtcactgtgaagtacacgcaggggagttggaccggcttcgttggggaggacgtggtcacc
atccccaaaggcttcaacagttcttttcttgtcaacatcgccaccatatttgagtcagag
aatttctttctgcctgggattagatggaatgggatacttggactggcttatgctaccctg
gccaagccttcaagttctctggagaccttctttgattccctcgtggcacaagcaaaaatc
cccaacatcttctccatgcagatgtgtggggccggactgccagtagctggatctggtacc
aacggaggtagtcttgtcctaggtggaattgaaccaactttgtacaaaggagacatctgg
tacacccctattaaggaggagtggtattatcagatagaaattctaaaattggaaattgga
ggccagagccttaacctggactgcagagagtacaatgcggacaaggccatcgtggacagt
ggcaccacgctgctgcgcctgccccagaaggtgtttgacgccgtggtggaggctgtggcc
cgcacatctctgattccagaattctctgaaggtttctggactggttcccagctggcatgc
tggacaaattctgaaacaccttggtcttatttccctaaaatctccatctacctgagagac
gagaactccagcagatcattccgtataactatcctgcctcagctttacattcagcccatg
atgggggctggcctgaattatgaatgttaccggttcggcatctcgccttccaccaacgca
ctggtgattggtgctaccgtcatggagggcttctacgtggtctttgacagagcccggaag
agagtgggcttcgcggccagcccctgtgcagaaatcgcaggtgctccggtgtctgaaatt
tctgggccgttctcaacagaggacatagccagcaactgcgtccctgccctgccgttgaac
gagcccattttgtggatcgtctcctatactcttatgagcgtgtgtggagtcattcttctc
gttttaatcaccctgctgctacttccggtccggtgtaggcatcacccccgagatcccgag
gtggtcaacgatgagtcctcgctcgtacggcatcgctggaaatga
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