Bubalus bubalis (water buffalo): 102400750
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Entry
102400750 CDS
T05912
Symbol
JAK3
Name
(RefSeq) tyrosine-protein kinase JAK3 isoform X1
KO
K11218
Janus kinase 3 [EC:
2.7.10.2
]
Organism
bbub
Bubalus bubalis (water buffalo)
Pathway
bbub04062
Chemokine signaling pathway
bbub04151
PI3K-Akt signaling pathway
bbub04217
Necroptosis
bbub04550
Signaling pathways regulating pluripotency of stem cells
bbub04630
JAK-STAT signaling pathway
bbub04658
Th1 and Th2 cell differentiation
bbub04659
Th17 cell differentiation
bbub05161
Hepatitis B
bbub05162
Measles
bbub05166
Human T-cell leukemia virus 1 infection
bbub05169
Epstein-Barr virus infection
bbub05200
Pathways in cancer
bbub05203
Viral carcinogenesis
bbub05223
Non-small cell lung cancer
bbub05340
Primary immunodeficiency
Brite
KEGG Orthology (KO) [BR:
bbub00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
102400750 (JAK3)
04151 PI3K-Akt signaling pathway
102400750 (JAK3)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
102400750 (JAK3)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
102400750 (JAK3)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
102400750 (JAK3)
04659 Th17 cell differentiation
102400750 (JAK3)
04062 Chemokine signaling pathway
102400750 (JAK3)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
102400750 (JAK3)
05203 Viral carcinogenesis
102400750 (JAK3)
09162 Cancer: specific types
05223 Non-small cell lung cancer
102400750 (JAK3)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
102400750 (JAK3)
05161 Hepatitis B
102400750 (JAK3)
05162 Measles
102400750 (JAK3)
05169 Epstein-Barr virus infection
102400750 (JAK3)
09163 Immune disease
05340 Primary immunodeficiency
102400750 (JAK3)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
bbub01001
]
102400750 (JAK3)
Enzymes [BR:
bbub01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
102400750 (JAK3)
Protein kinases [BR:
bbub01001
]
Non-receptor tyrosine kinases
JAK family [OT]
102400750 (JAK3)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
SH2_1
FERM_F1
Jak1_Phl
Kdo
ABC1
FERM_C_FAK1
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
102400750
NCBI-ProteinID:
XP_025149613
LinkDB
All DBs
Position
9:complement(105049887..105069422)
Genome browser
AA seq
1134 aa
AA seq
DB search
MKAETRLDLCCTLLCGPNALYTGSAQQAALMAPPSEETPLISQRSCSLSSSEAGALHVLL
PPRGPGPPQCLSFSFGDHSAEDLCVCAAKASGILPVYHSLFALALEDLSCWFPPSHIFSV
EDTGTQVLVYRLRFYFPNWFGLEKCHRFGLRKDLTSAILDLPVLEHLFAQHRHDLVSGRL
RVGLSLKEQGECLSLAVLDLARMALEQAQRPEELLKTVSYKVCLPPGLRDLIQGLSFVTR
RRIRRTVRRALRGVAACQADRHSLMVKYIMDLERLDPDRAAETFRVGLPGAAGGQDTPGL
LRVAGGSGIAWSPGEHEVLQPFCDFPEIVDISIKQAPCIGPAAEHRLVTITRTDNQILEA
EFPGLPAALSFVALVDGYFRLTTDSRHYFCKEVAPPRLLDEVAEQCHGPITLDFAINKLK
TGGSLPGSYVLRRSPQDFDSYLLTVCVLTPLGPDYKGCLIRCDPTGTFSLAGLGRSHSSL
RELLAACWNGGLHVDGVELYLTFCCNPRPKEKSNLIVVRRGCNPPTSSPVQPQFQCQLSQ
MTFHKIPADSLQWHENLGHGSFTKIYRGCHHETVDGEARETEVLLKVMDAKHKNCMESFL
EAASLMSQVSYQHLVLLHGVCMAGDSIMVQEFVRLGALDTYLRKCGHLVPASWKLQVIKQ
LAYALNYLEDKGLPHGNVSARKVLLAREGTDGNLPFIKLSDPGVSPTVLSLEMLTDRIPW
VAPECLQEARTLGLEADKWGFGATVWEVFSGVTVPISTLEPAKKLQFYQERQQLPAPKWM
ELALLIQQCMAYEPGQRPSFRAVIRDLNSLITSDYELLSDPTPGTLAPRDGLWNGTQLYA
CQDPTIFEERHLKYISQLGKGNFGSVELCRYDPLGDNTGALVAVKQLQHSGPEQQRDFQR
EIQILKALHSDFIVKYRGVSYGPGRQSLRLVMEYLPSGCLRDFLQRHRARLDAGRLLLYA
SQICKGMEYLGSCRCLHRDLAARNILVESETHVKIADFGLAKLLPLDKDYYVVREPGQSP
IFWYAPESLSDNIFSRQSDVWSFGVVLYELFTYSDKNCSPSAEFLRMMGCERDVPALCRL
LELLAEGQRLPAPPACPSEVHELMKLCWAPNPQDRPSFSALGPQLDALWSGSRG
NT seq
3405 nt
NT seq
+upstream
nt +downstream
nt
atgaaggcagagacgagactggatctgtgctgtaccctgctgtgtggccccaatgccctg
tacaccggaagtgcccagcaggctgcactcatggcacctccaagtgaggagacacccctg
atttctcagcgctcctgcagcctctcctcttcagaggctggtgccctgcacgtgctgctg
ccccctcggggccctggacccccacagtgcctgtccttctcctttggggaccactcagct
gaagacctgtgtgtttgcgctgctaaggccagtggcatcctgcccgtgtaccactccctc
tttgctctggctttggaagacctgtcctgctggttccccccgagccacatcttctccgtg
gaggacacgggtacccaggtcctcgtctacaggctccgcttttacttccctaactggttt
ggactagagaagtgccaccgatttgggctacgaaaggacttgaccagcgccatcttggat
ctgccagtcctggagcacctctttgctcagcaccgccatgacctggtgagcggccgcctc
cgggtaggcctcagcctcaaggaacagggtgagtgtctcagcttggctgttctggacctg
gcccggatggccctcgagcaggctcagcggcccgaggagttgctgaagacggtcagctac
aaggtctgcctgccccctggcctacgcgacctgatccagggtttgagcttcgtgactcgg
aggcgcatccgaaggacagtgcgccgggccttgcgcggcgtggcggcctgccaggctgac
aggcactcactcatggtcaagtacatcatggacctcgagaggctggatccagacagggcc
gccgagaccttccgcgtgggtctccccggcgctgctggtggtcaggatacgccggggctg
ctccgtgtggctggtggcagtggcatcgcctggagcccaggagaacacgaggtcctccag
cccttctgcgactttccagaaatcgtggatatcagcatcaagcaggcgccgtgcattggc
ccggctgccgagcaccgcttggtcaccatcaccaggacagacaatcagatcctggaggcc
gagttcccggggcttcccgcagcgttgtccttcgtggcgctcgtggatggctacttccgg
ctgaccacggactcgaggcactacttctgcaaggaggtggcgccgccgcggctgctggac
gaggtggctgagcagtgccatggccccatcaccctggattttgccatcaacaaactcaag
actgggggctcacttcccggctcctacgtcctccgccgcagtccccaggatttcgacagc
tacctcctaactgtttgtgtcctgacccccctggggccggattataagggctgcctcatc
cggtgcgaccccacaggaaccttctccctggctggccttggccgttcccacagcagtctt
cgagagcttctggcagcctgttggaatggtgggttgcacgtggatggggttgagctgtac
ctcaccttctgctgcaaccccagacctaaagaaaagtccaatctgattgtggtccggaga
ggctgcaacccacccacatcatcccctgttcagccccaattccagtgccagctgagtcag
atgacgtttcacaagatccctgctgacagcctgcagtggcatgagaacctaggtcacggg
tccttcaccaagatttatcggggctgtcaccatgagactgtggatggggaggcccgagag
acagaggtactgctcaaagtgatggatgccaagcacaagaattgcatggagtcattcctg
gaagcagcgagcttgatgagccaagtgtcataccagcatctcgtattgctccacggcgtg
tgcatggctggagacagtatcatggttcaggaatttgtacgcctgggagcactggacaca
tatctacgcaagtgtggccacctagtgccagccagctggaagctacaggtgatcaaacag
ctggcctatgccctcaactatctggaagacaaaggtctccctcatggcaatgtctcagcc
cggaaggtgctcttggctcgtgaggggactgatgggaacctgcctttcatcaagctaagt
gacccgggtgtcagccccacggtgctaagcctggagatgctcactgacaggatcccctgg
gtggcccctgaatgtctccaggaggcccgaacacttggcttggaagctgacaagtggggc
tttggagccacagtctgggaggtgttcagtggtgtcacagtgcccatcagcaccctggag
cctgccaagaagctccagttttaccaggaacggcagcagttgcctgcccctaagtggatg
gagctggccctgctgatccaacagtgcatggcctatgagccaggccagaggccctctttc
cgcgccgtcatccgtgacctgaacagcctcatcacttcagattatgagctcctctcagac
cccacacctggcaccctggcaccccgtgacgggctctggaatggcacccagctctacgcc
tgccaggaccctaccatctttgaagagagacacctcaaatacatctcacagctgggcaag
ggcaactttggcagcgtggaactgtgccgctatgacccgctgggcgacaacacaggggcc
ctggtggccgtgaagcagttgcagcatagtgggccagaacagcagagggacttccagcgg
gagatccagatcctcaaagccctccacagtgacttcattgtcaagtaccggggtgtcagc
tatggcccaggccgccagagcctgcggttggtcatggagtatctgcccagtggctgcctg
cgcgacttcctgcagcggcaccgcgcccgcctcgacgctggccgcctgctcctctacgcc
tcacagatctgcaagggcatggagtacctgggctcctgccgctgcctgcaccgcgacctg
gcagcccggaacatcctggtggaaagcgagacgcacgtcaagatcgccgacttcggcctg
gccaagctgctgcctctcgacaaagactactacgtggtccgcgagccaggccagagcccc
atcttctggtatgccccagagtccctctcggacaacatcttctcgcgccagtcggatgtc
tggagcttcggggtcgtcctgtacgagctcttcacctacagtgacaagaactgtagcccc
tcagccgagttcctgcggatgatgggatgtgagagagatgttccagccctctgccgtctc
ctggagctgctggccgagggccagaggctgcctgcacctcccgcctgtcctagtgaggtt
catgagctcatgaagctgtgctgggcacctaaccctcaagaccggccatcattcagtgcc
ctgggcccccagctggatgcgttgtggagtggaagccggggatag
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integrated database retrieval system
