KEGG   Bubalus bubalis (water buffalo): 102401425
Entry
102401425         CDS       T05912                                 
Symbol
PINK1
Name
(RefSeq) serine/threonine-protein kinase PINK1, mitochondrial
  KO
K05688  PTEN induced putative kinase 1 [EC:2.7.11.1]
Organism
bbub  Bubalus bubalis (water buffalo)
Pathway
bbub04137  Mitophagy - animal
bbub05012  Parkinson disease
bbub05014  Amyotrophic lateral sclerosis
bbub05022  Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:bbub00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04137 Mitophagy - animal
    102401425 (PINK1)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05012 Parkinson disease
    102401425 (PINK1)
   05014 Amyotrophic lateral sclerosis
    102401425 (PINK1)
   05022 Pathways of neurodegeneration - multiple diseases
    102401425 (PINK1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:bbub01001]
    102401425 (PINK1)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:bbub04131]
    102401425 (PINK1)
   03029 Mitochondrial biogenesis [BR:bbub03029]
    102401425 (PINK1)
Enzymes [BR:bbub01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     102401425 (PINK1)
Protein kinases [BR:bbub01001]
 Serine/threonine kinases: Other
  NKF2 family
   102401425 (PINK1)
Membrane trafficking [BR:bbub04131]
 Autophagy
  Mitophagy
   PINK1-Parkin associated proteins
    102401425 (PINK1)
Mitochondrial biogenesis [BR:bbub03029]
 Mitochondrial quality control factors
  Mitophagy factors
   Parkin-dependent mechanism factors
    102401425 (PINK1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like
Other DBs
NCBI-GeneID: 102401425
NCBI-ProteinID: XP_025134596
LinkDB
Position
2:complement(184008222..184028737)
AA seq 588 aa
MAVRQALGRGLQLGRALLLRFTAKPGPAYGWGRPERPGPAAGWGRGERPGPAAGPGTEPC
RLGLGLPGRYRFFRQSVAGLAERLQRQFVVRARGGAGPCGRAVFLAFGLGLGLIEEKQAE
GRRAASACEEIQAIFTQKNKLLPDPLDTRRWQGFRLEEYLIGQSIGKGCSAAVYEAAMPV
WPQNLEEAESLGQLLPGKGPEILPRGEEAPAPRAPAFPLAIKMMWNISAGSSSEAIFSTM
SQELVPASRVALAGEYGAVTHRRPKGGPKQLAPHPNIIRVLRAFTSSVPLLPGALVDYPD
VLPPRLHPAGLGHGRTLFLVMKNYPCTLRQYLRRNTPSPRLATAMTLQLLEGVDHLVQQG
VAHRDLKSDNILVELDADGCPWLVIADFGCCLADERVGLQLPFTSWYVDRGGNGCLMAPE
VSTACPGPRAVIDYSKADAWAVGALAYEIFGLPNPFYGQGRAHLESRSYQEAQLPALPEW
VPRDVRCLVRSLLQREVCKRPSARVAANVLHLSLWGEHTLTPKNLKLDKMIAWLLQQSAA
TLLANRLTGKNCVETKMKMLFLANLEYEALSQAALLLNSWRAAPRQLL
NT seq 1767 nt   +upstreamnt  +downstreamnt
atggcggtgcgacaggcgctgggccggggcctgcagctgggccgagcgctgctcctgcgc
ttcacggccaagcccggcccggcctacggctggggccggccggagcggccgggccccgcg
gcgggctggggccgcggagagcgcccgggccctgccgcgggacccggcacggagccgtgc
aggctcgggctcgggcttcccggccgctaccgcttcttccgccagtcggtggccgggctg
gcggagcggctccagcggcagttcgtggtgcgggcccggggcggtgcgggcccttgcggc
cgcgctgtctttctggccttcgggcttgggctgggcctcatcgaggagaagcaagcggag
ggccggcgggccgcctcagcctgtgaggagatccaggcaattttcacccagaaaaacaag
ctgctcccagacccactggacacccgacgctggcagggtttccggctggaggagtatctg
atcgggcagtccattggcaagggctgcagtgccgccgtctacgaggccgccatgcctgtg
tggccccagaacctggaggaggcagagagcctgggccagcttcttccagggaagggccca
gagatccttccacgaggagaggaggcgccagccccacgggccccggccttccccttggcc
atcaagatgatgtggaacatctcggcaggctcatccagcgaagccatctttagcacaatg
agccaggagctggtcccagccagtcgagtggccttggccggggagtatggagcggtcact
cacagaagacccaagggaggtcccaagcagctggccccgcaccccaacatcatccgggtc
ttgcgagccttcacctcgtcggtgccgctgctgccaggggccctggtcgactacccggac
gtgctgcccccgcgtcttcaccccgcaggcctgggccacgggcggactctcttcctcgtc
atgaagaactacccgtgtaccctgcgccagtacctccgcaggaacaccccgagcccccgg
ctggccactgcgatgactctgcagctcttggaaggggtggaccacctggtccagcagggc
gtcgcgcacagagacctgaagtctgacaacatcctggtggaactggatgcagacggctgc
ccctggttggtgatcgcagactttggctgctgcctggctgatgagcgcgtcggcctgcag
ttgcctttcaccagctggtacgtggaccgcggcgggaacggctgcctgatggctcccgag
gtgtccacggcctgccctggccccagggcagtgatcgactacagcaaggcggatgcctgg
gcggtgggcgcactcgcctacgaaatcttcgggctccccaatcccttttacggccagggc
agggcccaccttgaaagccgcagttaccaggaggctcagctgccagcactgcccgagtgg
gtgccgcgggacgtgaggtgcctggtgaggtcgctgctgcagcgggaggtctgcaagagg
ccatccgcccgagtggctgctaatgtgcttcatttaagcctctggggtgaacacacactc
accccaaagaacctgaaactagacaagatgattgcctggctcctccaacaatcggccgcc
actctgctggccaacaggctgacgggaaagaactgtgtggaaacaaaaatgaagatgcta
tttctggccaacctggagtatgaagcgctgagccaggcggccctcctcctcaactcctgg
cgggcagccccgagacagctactgtag

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