Bubalus bubalis (water buffalo): 102401701
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Entry
102401701 CDS
T05912
Symbol
MMP2
Name
(RefSeq) 72 kDa type IV collagenase
KO
K01398
matrix metalloproteinase-2 (gelatinase A) [EC:
3.4.24.24
]
Organism
bbub
Bubalus bubalis (water buffalo)
Pathway
bbub01522
Endocrine resistance
bbub04670
Leukocyte transendothelial migration
bbub04912
GnRH signaling pathway
bbub04915
Estrogen signaling pathway
bbub04926
Relaxin signaling pathway
bbub04933
AGE-RAGE signaling pathway in diabetic complications
bbub05200
Pathways in cancer
bbub05205
Proteoglycans in cancer
bbub05219
Bladder cancer
bbub05415
Diabetic cardiomyopathy
bbub05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
bbub00001
]
09150 Organismal Systems
09151 Immune system
04670 Leukocyte transendothelial migration
102401701 (MMP2)
09152 Endocrine system
04912 GnRH signaling pathway
102401701 (MMP2)
04915 Estrogen signaling pathway
102401701 (MMP2)
04926 Relaxin signaling pathway
102401701 (MMP2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
102401701 (MMP2)
05205 Proteoglycans in cancer
102401701 (MMP2)
09162 Cancer: specific types
05219 Bladder cancer
102401701 (MMP2)
09166 Cardiovascular disease
05418 Fluid shear stress and atherosclerosis
102401701 (MMP2)
05415 Diabetic cardiomyopathy
102401701 (MMP2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
102401701 (MMP2)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
102401701 (MMP2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
bbub01002
]
102401701 (MMP2)
Enzymes [BR:
bbub01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.24 Metalloendopeptidases
3.4.24.24 gelatinase A
102401701 (MMP2)
Peptidases and inhibitors [BR:
bbub01002
]
Metallo peptidases
Family M10
102401701 (MMP2)
BRITE hierarchy
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Peptidase_M10
fn2
Hemopexin
PG_binding_1
Reprolysin_3
Reprolysin_5
Peptidase_M66
Reprolysin_4
Motif
Other DBs
NCBI-GeneID:
102401701
NCBI-ProteinID:
XP_006053742
LinkDB
All DBs
Position
18:23368587..23396511
Genome browser
AA seq
661 aa
AA seq
DB search
MTEARVSRGALFAPLRALCVLGCLLGRAAAAPSPIIKFPGDVAPKTDKELAVQYLNTFYG
CPKESCNLFVLKDTLKKMQKFFGLPQTGELDQSTIETMRKPRCGNPDVANYNFFPRKPKW
DKNQITYRIIGYTPDLDPQTVDDAFARAFQVWSDVTPLRFSRIHDGEADIMINFGRWEHG
DGYPFDGKDGLLAHAFAPGPGVGGDSHFDDDELWTLGEGQVVRVKYGNADGEYCKFPFRF
NGKEYTSCTDIGRSDGFLWCSTTYNFDKDGKYGFCPHEALFTMGGNADGQPCKFPFRFQG
TSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPETAMSTVGGNSEGAPCVLPFTFLGNK
HESCTSAGRSDGKLWCATTSNYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGA
LMAPIYTYTKNFRLSHDDIQGIQELYGASPDIDTGTGPTPTLGPVTPELCKQDIVFDGIS
QIRGEIFFFKDRFIWRTVTPRDKPTGPLLVATFWPELPEKIDAVYEDPQEEKAVFFAGNE
YWVYSASTLERGYPKPLTSLGLPPDVQKVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKMD
PGFPKLIADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLKSVKFGSIKSDWLG
C
NT seq
1986 nt
NT seq
+upstream
nt +downstream
nt
atgaccgaggcgcgagtgtcccggggcgcgctgttcgcccctctgcgggcgctctgcgtc
ctgggctgcctgttgggccgtgccgccgccgcgccgtcgcccatcatcaaatttcccggc
gatgtcgcccccaaaacggacaaagagttggctgtgcaatacctaaacaccttctacggc
tgccccaaggagagctgtaacttgtttgtgctgaaggacaccctgaagaagatgcagaag
ttcttcgggttaccccagacaggtgaactggaccagagcaccatcgagaccatgcggaag
ccgcgctgtggcaaccccgacgtggccaactacaacttctttccccgaaagcccaagtgg
gacaagaaccagatcacatacaggatcattggctacacacctgatttggacccccagaca
gtggatgatgccttcgctcgtgccttccaagtctggagcgatgtgaccccgctacggttt
tctcggatccatgatggagaggctgacatcatgatcaactttggccgctgggagcatgga
gatgggtacccttttgatggcaaagatgggctcctggctcatgccttcgccccgggccct
ggagttgggggagattcccacttcgacgacgatgagctgtggactctaggagaaggacaa
gtggtccgtgtgaagtacgggaatgctgacggggaatattgcaagttccccttccggttc
aacggcaaggagtacaccagctgcacagacataggccgcagcgatggcttcctctggtgc
tccaccacgtacaactttgacaaggacggcaagtatggcttctgcccccatgaagccctg
ttcaccatgggcggcaacgctgacggacagccctgcaagttcccgttccgcttccagggc
acgtcttacgacagctgcaccacggagggccgcacggacggctaccgctggtgtggcacc
accgaggactatgaccgtgacaagaagtacggcttctgcccggagactgccatgtccact
gtgggcgggaactcagaaggtgccccatgtgtcctccccttcaccttcctgggcaacaag
cacgagagctgcaccagcgctggccgcagtgatgggaagctgtggtgtgcgaccacctcc
aactacgatgatgaccgcaagtggggcttctgccccgaccaagggtacagcctgttcctg
gtggcagcccatgagtttggccatgcaatggggctggagcactcacaggaccctggagcc
ctgatggcacccatttatacctatactaagaacttccgcctgtcccatgatgacatccag
ggcatccaagaactctatggagcctcccctgacattgatactggcaccggccccacccca
accctgggccctgtcactcctgagctctgcaaacaggacatcgtcttcgatggcatctct
cagatccgtggggagatcttcttcttcaaggaccgattcatctggcgaacagtgacacca
cgtgacaagcccacagggcccctgctggtagccacattctggcctgagctaccggaaaag
atcgatgctgtgtacgaagacccacaggaggagaaggctgtgttctttgcagggaacgaa
tactgggtctattcagccagtaccctggagcgagggtaccccaagccgctgaccagcctg
gggctcccccctgatgtccagaaggtggatgctgcctttaactggagcaagaacaagaag
acgtacatcttcgccggagacaaattctggagatacaatgaggtgaagaagaaaatggat
cctggcttccccaagctcatcgccgatgcctggaacgccatccctgataacctggatgct
gtggtggacctgcagggcgggggtcacagctacttcttcaagggcgcctattacctgaag
ttggagaaccaaagtctgaagagcgtgaagtttggaagcatcaaatccgattggctgggc
tgctga
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