KEGG   Bubalus bubalis (water buffalo): 102402077
Entry
102402077         CDS       T05912                                 
Symbol
BCL2
Name
(RefSeq) apoptosis regulator Bcl-2 isoform X3
  KO
K02161  apoptosis regulator Bcl-2
Organism
bbub  Bubalus bubalis (water buffalo)
Pathway
bbub01521  EGFR tyrosine kinase inhibitor resistance
bbub01522  Endocrine resistance
bbub01524  Platinum drug resistance
bbub04064  NF-kappa B signaling pathway
bbub04066  HIF-1 signaling pathway
bbub04071  Sphingolipid signaling pathway
bbub04115  p53 signaling pathway
bbub04140  Autophagy - animal
bbub04141  Protein processing in endoplasmic reticulum
bbub04151  PI3K-Akt signaling pathway
bbub04210  Apoptosis
bbub04215  Apoptosis - multiple species
bbub04217  Necroptosis
bbub04261  Adrenergic signaling in cardiomyocytes
bbub04340  Hedgehog signaling pathway
bbub04510  Focal adhesion
bbub04621  NOD-like receptor signaling pathway
bbub04630  JAK-STAT signaling pathway
bbub04722  Neurotrophin signaling pathway
bbub04725  Cholinergic synapse
bbub04915  Estrogen signaling pathway
bbub04928  Parathyroid hormone synthesis, secretion and action
bbub04933  AGE-RAGE signaling pathway in diabetic complications
bbub05014  Amyotrophic lateral sclerosis
bbub05022  Pathways of neurodegeneration - multiple diseases
bbub05132  Salmonella infection
bbub05145  Toxoplasmosis
bbub05152  Tuberculosis
bbub05161  Hepatitis B
bbub05162  Measles
bbub05168  Herpes simplex virus 1 infection
bbub05169  Epstein-Barr virus infection
bbub05170  Human immunodeficiency virus 1 infection
bbub05200  Pathways in cancer
bbub05206  MicroRNAs in cancer
bbub05207  Chemical carcinogenesis - receptor activation
bbub05210  Colorectal cancer
bbub05215  Prostate cancer
bbub05222  Small cell lung cancer
bbub05226  Gastric cancer
bbub05417  Lipid and atherosclerosis
bbub05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:bbub00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    102402077 (BCL2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04340 Hedgehog signaling pathway
    102402077 (BCL2)
   04630 JAK-STAT signaling pathway
    102402077 (BCL2)
   04064 NF-kappa B signaling pathway
    102402077 (BCL2)
   04066 HIF-1 signaling pathway
    102402077 (BCL2)
   04071 Sphingolipid signaling pathway
    102402077 (BCL2)
   04151 PI3K-Akt signaling pathway
    102402077 (BCL2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    102402077 (BCL2)
  09143 Cell growth and death
   04210 Apoptosis
    102402077 (BCL2)
   04215 Apoptosis - multiple species
    102402077 (BCL2)
   04217 Necroptosis
    102402077 (BCL2)
   04115 p53 signaling pathway
    102402077 (BCL2)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    102402077 (BCL2)
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    102402077 (BCL2)
  09152 Endocrine system
   04915 Estrogen signaling pathway
    102402077 (BCL2)
   04928 Parathyroid hormone synthesis, secretion and action
    102402077 (BCL2)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    102402077 (BCL2)
  09156 Nervous system
   04725 Cholinergic synapse
    102402077 (BCL2)
   04722 Neurotrophin signaling pathway
    102402077 (BCL2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    102402077 (BCL2)
   05206 MicroRNAs in cancer
    102402077 (BCL2)
   05207 Chemical carcinogenesis - receptor activation
    102402077 (BCL2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    102402077 (BCL2)
   05226 Gastric cancer
    102402077 (BCL2)
   05215 Prostate cancer
    102402077 (BCL2)
   05222 Small cell lung cancer
    102402077 (BCL2)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    102402077 (BCL2)
   05161 Hepatitis B
    102402077 (BCL2)
   05162 Measles
    102402077 (BCL2)
   05168 Herpes simplex virus 1 infection
    102402077 (BCL2)
   05169 Epstein-Barr virus infection
    102402077 (BCL2)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    102402077 (BCL2)
   05152 Tuberculosis
    102402077 (BCL2)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    102402077 (BCL2)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    102402077 (BCL2)
   05022 Pathways of neurodegeneration - multiple diseases
    102402077 (BCL2)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    102402077 (BCL2)
   05418 Fluid shear stress and atherosclerosis
    102402077 (BCL2)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    102402077 (BCL2)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    102402077 (BCL2)
   01524 Platinum drug resistance
    102402077 (BCL2)
   01522 Endocrine resistance
    102402077 (BCL2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:bbub01009]
    102402077 (BCL2)
Protein phosphatases and associated proteins [BR:bbub01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     102402077 (BCL2)
SSDB
Motif
Pfam: Bcl-2 BH4 Bcl-2_3 ARMH5
Other DBs
NCBI-GeneID: 102402077
NCBI-ProteinID: XP_006064629
LinkDB
Position
22:634619..829778
AA seq 229 aa
MAHAGGTGYDNREIVMKYIHYKLSQRGYEWDAGDAGAAPPGAAPAPGILSSQPGRTPAPS
RTSPPPPPAAAAGPAPSPVPPVVHLTLRQAGDDFSRRYRRDFAEMSSQLHLTPFTARGRF
ATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDSIALWMTEYLNRHLHTWIQ
DNGGWDAFVELYGPSMRPLFDFSWLSLKALLSLALVGACISLGAYLGHK
NT seq 690 nt   +upstreamnt  +downstreamnt
atggcgcacgcggggggaacaggctacgataaccgagagatcgtgatgaagtacatccac
tataagctgtcgcagcggggctacgagtgggatgccggagacgcgggcgccgcgcccccc
ggggccgctcccgcgccgggcatcctgtcctcccagccgggccgcacacccgcgccctcc
aggacctccccgccgccgcccccggccgccgccgccgggcctgcgcccagcccggtgcca
cctgtggtccacctgaccctgcgccaggccggcgatgacttctctcggcgctaccgccgc
gacttcgccgagatgtccagccagctgcacctgacgcccttcaccgcgaggggacgcttc
gccacggtggtggaggagctcttcagggacggggtgaactgggggcgcatcgtggccttc
tttgagttcggaggggtcatgtgtgtggagagcgtcaaccgggagatgtcgcccctggtg
gacagcatcgccctgtggatgaccgagtacctgaaccggcacctgcacacctggatccag
gacaacggaggctgggacgcctttgtggagctgtatggccccagcatgcggcccctgttt
gatttctcctggctgtctctgaaggcactgctcagtctggccctggtgggcgcttgcatc
agcctgggtgcgtatctgggccataagtga

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