Bubalus bubalis (water buffalo): 102404389
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Entry
102404389 CDS
T05912
Symbol
RET
Name
(RefSeq) proto-oncogene tyrosine-protein kinase receptor Ret isoform X1
KO
K05126
proto-oncogene tyrosine-protein kinase Ret [EC:
2.7.10.1
]
Organism
bbub
Bubalus bubalis (water buffalo)
Pathway
bbub04010
MAPK signaling pathway
bbub04020
Calcium signaling pathway
bbub04151
PI3K-Akt signaling pathway
bbub05200
Pathways in cancer
bbub05216
Thyroid cancer
bbub05223
Non-small cell lung cancer
bbub05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
bbub00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
102404389 (RET)
04020 Calcium signaling pathway
102404389 (RET)
04151 PI3K-Akt signaling pathway
102404389 (RET)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
102404389 (RET)
05230 Central carbon metabolism in cancer
102404389 (RET)
09162 Cancer: specific types
05216 Thyroid cancer
102404389 (RET)
05223 Non-small cell lung cancer
102404389 (RET)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
bbub01001
]
102404389 (RET)
Enzymes [BR:
bbub01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
102404389 (RET)
Protein kinases [BR:
bbub01001
]
Receptor tyrosine kinases (RTK)
RET family
102404389 (RET)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
RET_CLD4
RET_CLD1
Pkinase
RET_CLD3
RET_CRD
Cadherin
Pkinase_fungal
RIO1
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
102404389
NCBI-ProteinID:
XP_006050814
LinkDB
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Position
4:132843951..132931596
Genome browser
AA seq
1114 aa
AA seq
DB search
MAKATASTVGLRLLLLLLPLLGEAPLGLYFSRDAYWEKLYVDQPAGTPLLYVHALRDVPE
EVPSFRLGQHLYGAYRTRLHENDWVRIQEDTGLLYLNQSLDHSSWEKLNIRNGGFPLLTV
YLRVFLSPASLREGECQWPGCARVYFSVINASFPACGALKPRELCFPESGLSFRIRENRP
PGTFHQFRLLPVQFLCPNVSVAYRLLGGESLPFRCDPDSLEVSTRWALDREQREKYELVA
ACTVRVGAREEEVMVPFPVTVYDEDDSAPTFLGGVDSASAVVEFKRKEGTVVATLRVFDA
DVVPASGELLRRYTNTLLSGDPKALRTFRVEHAPNETLAQANGSFVRATVHDYRLVLNRS
LPISESWAVQLAVLVNDSDFQGPGEGVVLLHFNVSVLPVSLRLPSAYSFSVSRRAHRFAQ
IGKVCVENCQEFSGIQVQYRLQPSSANCSALGMVTSAEDTSGTLFVNDVEALQRPECAQL
QYTVVAAEKPTRQQAQAPLFVSVEGIYVPEEPGCPLSCAVSKRRPECEECGGLGSLTGRC
EWRQGDGKGITRNFSTCSPSIRTCPDGHCDAVESRDPNICPQDCLRGGSIIGGHEPGERR
GIKAGFGICNCFPEEKKCFCEPEDSQDSLCDELCRTVITAAVLFSFIVSVLLSTFCIHRY
HKNAHKPPIASAEMTFRRPAQAFPVSYSSSGARRPSLDSMENQVSVDTFKIPEDPKWEFP
RKNLVLGKTLGEGEFGKVVKATAFRLKGKAGYTTVAVKMLKENASPSELRDLLSEFNLLK
QVNHPQVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKAGPGYVGSGGSRNSSYLDN
PEERALTMGDLISFAWQISRGMQYLAEMKLVHRDLAARNVLVAEGRRMKISDFGLSRDVY
EEDSYVKRSKGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERL
FNLLKTGYRMERPDNCSEEMYNLMLQCWKQEPDKRPVFADISKDLDKMMVKSRDYLDLAA
STPSDSLLYDDGLSEEETPLVDCNNAPLPRTLPSTWIENKLYGMSDPNWPEESPVPLTRA
AGTNIGCPRYANDSVYANWMVSPSAAQLMDAFDS
NT seq
3345 nt
NT seq
+upstream
nt +downstream
nt
atggcgaaggcgacggccagcaccgtggggctgcggttgctgcttctgctgctgcccctg
ctcggcgaagccccgctgggactctacttctccagggacgcttactgggagaagctatac
gtggaccagccggccggcacgcccctgctctatgtccacgccctgcgggacgtgccggag
gaggtgcccagcttccgcctgggccagcacctctacggggcctaccgcacgcggctgcac
gagaacgactgggtccgcatccaggaggacacggggcttctctaccttaaccagagcctg
gaccacagctcctgggagaagctcaacatccgcaacggcggcttcccactgcttaccgtc
tatctccgggtcttcctgtcacccgcgtcccttcgtgagggcgagtgccagtggccgggc
tgtgcccgtgtgtacttctccgtcatcaatgcctccttcccggcttgtggtgccctcaaa
ccccgggagctctgcttccccgagtcaggcctgtccttccgcatccgggagaacaggccc
cccggcaccttccaccagttccgcctgctgcccgtgcaattcctctgccccaacgtcagc
gtggcctacaggctcctgggaggtgagagtctgcctttccgctgcgatccggacagcctg
gaggtgagcacgcgctgggccctggaccgcgagcagcgggagaagtatgagctggtggcc
gcgtgcacggttcgcgtgggcgcgcgcgaggaggaggtgatggtgcccttccccgtgacc
gtgtacgacgaggacgactctgcgcccaccttcctcgggggcgtcgacagcgccagcgcc
gtggtggagttcaagcggaaggagggcacagtggtagccacgttacgtgtcttcgatgca
gacgtggtgccagcctccggggagctcctgagacggtacacgaacacgctgctctctggg
gaccccaaggccctccggaccttccgagtggagcacgcgcccaatgagaccttggcccag
gccaacggcagctttgtgagggcaaccgtgcatgactacaggctggttctcaaccggagc
ctccccatctcggagagctgggctgtgcagctggccgtgctggtcaacgactcagacttc
cagggccctggggaaggtgttgtcctcctccacttcaacgtgtccgtgctgcccgtcagc
ctgcgcctgcccagcgcctactccttctcggtgagcaggcgggcccaccgctttgcccag
atcgggaaagtctgcgtggaaaactgccaggagttcagcggcatccaagtgcagtacagg
ctgcagccctccagcgccaactgcagcgccctggggatggtcacctcggccgaggacacc
tcggggaccctgttcgtgaatgacgtggaggccctgcagcggcccgagtgtgcccagctc
cagtacacggtggtggccgccgagaaaccaacccgccagcaagcccaggccccgctgttc
gttagcgtggaagggatatacgtgcctgaggagcctggctgccccctgtcctgcgcggtc
agcaagaggcggcccgaatgtgaggaatgcggcggcctgggctccctgacgggcaggtgc
gagtggaggcagggagacggcaaagggatcaccaggaacttctccacctgctcccccagc
atcaggacctgccccgatggccactgtgacgccgtggagagcagagaccccaacatctgc
ccccaggactgcctccggggcggcagcatcattggtgggcacgagcctggggagcgccgg
gggattaaagctggcttcggtatctgcaactgcttccctgaggagaagaagtgcttctgc
gagccggaggacagccaggactccctgtgtgatgagctctgccgcacagtgatcacggcg
gccgtgctcttctccttcatcgtgtctgtgctgctgtccaccttctgcatccaccgctac
cacaagaacgcccacaagccgcccattgcctcggccgagatgaccttccgccggcccgcc
caagccttcccggtcagctactcctcgtctggcgcccgccggccctctctggactccatg
gagaaccaggtctcggtggacaccttcaagatcccggaggatcccaagtgggaattccca
cggaagaacttggtgcttggaaaaactctgggagaaggcgaatttggaaaagtggttaag
gccacagccttccggctgaaaggcaaagcggggtacacgactgtggctgtgaagatgctg
aaagagaatgcctccccaagcgagctgcgggacctgctatcagagttcaacctcctgaag
caggtcaaccacccgcaagtcatcaagctgtatggggcctgcagccaggacgggccactg
ctcctcatcgtggagtatgccaagtacggctctctgcggggcttcctccgagagagccgc
aaggcggggcctggctacgtgggcagcgggggcagccgcaactccagttacctggacaac
ccggaggagcgggccctgaccatgggcgacctcatctcctttgcctggcagatttcacga
gggatgcaatacctggctgagatgaagcttgtccatcgggacttggcagccagaaacgtc
ctggtagctgagggccgcaggatgaagatctcagattttggtctgtcccgagatgtttat
gaagaggattcctatgtgaagaggagcaagggtcggatcccagttaagtggatggccatt
gagtccctcttcgatcatatctataccacccagagtgatgtgtggtcctttggcgtcctg
ctgtgggagattgtgaccctgggcggcaacccttaccctgggattcctccagagcggctc
ttcaaccttctgaagacaggctaccggatggagaggccggacaactgcagcgaggagatg
tacaatctgatgctgcagtgctggaagcaggaaccagacaagaggccagtgtttgccgac
atcagcaaagacctggataagatgatggttaagagcagagactacctggacctggccgcg
tccaccccatctgactccctgctgtatgacgacggcctgtcagaggaggagacgcccctg
gtggactgtaataacgctcccctccctcgcaccctcccctccacgtggattgaaaacaaa
ctctatggcatgtcagacccgaactggcctgaagagagtcctgtaccactcacgagagcc
gctggcaccaacattgggtgtccgagatatgcaaatgatagtgtttatgctaactggatg
gtttcaccctcagcggcacaattaatggacgcgtttgatagttaa
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