Bubalus bubalis (water buffalo): 102406784
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Entry
102406784 CDS
T05912
Symbol
LCK
Name
(RefSeq) tyrosine-protein kinase Lck isoform X3
KO
K05856
lymphocyte cell-specific protein tyrosine kinase [EC:
2.7.10.2
]
Organism
bbub
Bubalus bubalis (water buffalo)
Pathway
bbub04064
NF-kappa B signaling pathway
bbub04380
Osteoclast differentiation
bbub04650
Natural killer cell mediated cytotoxicity
bbub04658
Th1 and Th2 cell differentiation
bbub04659
Th17 cell differentiation
bbub04660
T cell receptor signaling pathway
bbub05135
Yersinia infection
bbub05166
Human T-cell leukemia virus 1 infection
bbub05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
bbub05340
Primary immunodeficiency
Brite
KEGG Orthology (KO) [BR:
bbub00001
]
09130 Environmental Information Processing
09132 Signal transduction
04064 NF-kappa B signaling pathway
102406784 (LCK)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
102406784 (LCK)
04660 T cell receptor signaling pathway
102406784 (LCK)
04658 Th1 and Th2 cell differentiation
102406784 (LCK)
04659 Th17 cell differentiation
102406784 (LCK)
09158 Development and regeneration
04380 Osteoclast differentiation
102406784 (LCK)
09160 Human Diseases
09161 Cancer: overview
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
102406784 (LCK)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
102406784 (LCK)
09171 Infectious disease: bacterial
05135 Yersinia infection
102406784 (LCK)
09163 Immune disease
05340 Primary immunodeficiency
102406784 (LCK)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
bbub01001
]
102406784 (LCK)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
bbub03036
]
102406784 (LCK)
Enzymes [BR:
bbub01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
102406784 (LCK)
Protein kinases [BR:
bbub01001
]
Non-receptor tyrosine kinases
SRC family
102406784 (LCK)
Chromosome and associated proteins [BR:
bbub03036
]
Eukaryotic type
Centrosome formation proteins
Kinases and associated factors
102406784 (LCK)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
SH2
SH3_1
SH3_2
SH3_9
ABC1
Kdo
Haspin_kinase
SH2_1
SH3_16
DUF4390
Motif
Other DBs
NCBI-GeneID:
102406784
NCBI-ProteinID:
XP_025134284
LinkDB
All DBs
Position
2:complement(173543184..173563989)
Genome browser
AA seq
458 aa
AA seq
DB search
MGCSCSSNPEDDWMENIDVCENCHYPIVPLDGKTTLPMRNGSEVRDPLVTYEGSNPPASP
LQDNLVIALHSYEPSHDGDLGFEKGEQLRILEQNGEWWKAQSLTTGQEGFIPFNFVAKAN
SLEPEPWFFKTLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQTQGEVVKH
YKIRNLDKGGFYISPRVTFPGLHELVRHYMRYYNGHTKVAVKSLKQGSMSPDAFLAEANL
MKQLQHQRLVRLYAVVTQEPIYIITEYMENGSLVDFLKTSEGIKLTINKLLDMAAQIAEG
MAFIEERNYIHRDLRAANILVSHSLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEA
INYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEELYQ
LMMLCWKERPEDRPTFDYLRSVLEDFFTATEGQYQPQP
NT seq
1377 nt
NT seq
+upstream
nt +downstream
nt
atgggctgtagctgcagctcaaacccagaagatgactggatggaaaacatcgatgtatgt
gaaaactgccactaccccatagtcccactggatggcaagaccacgctgcccatgcggaat
ggctctgaagtgcgtgatccactggtcacctacgagggatccaaccccccagcttctcca
ctgcaagacaacctggttatcgccctgcacagctatgagccttctcacgacggagacctg
ggcttcgagaagggtgaacagctccgtatcctggagcagaacggcgagtggtggaaggcg
cagtccctgaccacgggccaggaaggtttcatccccttcaactttgtggccaaagcgaac
agcctggagcccgaaccctggttcttcaagactctgagccgcaaggacgcggagaggcag
ctcctggcgccggggaacacgcacggctccttcctgatccgggagagcgagagcacggcg
ggatcgttttcactgtcggtccgggacttcgaccagacccagggagaagtggtgaaacat
tacaagatccgtaacctggacaaaggcggcttctacatctcgccccgcgtcacttttccc
ggcttgcacgagctggtccgccattatatgaggtactataacgggcacacgaaggtggca
gtcaagagcctgaagcagggcagcatgtcccccgatgccttcctggccgaggccaacctc
atgaagcagctgcaacaccagaggctggtccggctctacgcggtggtcacccaggagccc
atctacatcatcacggaatatatggagaacggaagcctggtggattttctcaagacctcc
gaaggcatcaagctgactatcaacaaactcttggacatggcagcccaaattgcagagggc
atggcattcattgaagagcggaattatatccaccgtgacttgagggctgccaacatcctg
gtgtcccatagcctgagctgcaagatcgcagactttggtctagcacgcctcatcgaggac
aacgagtacacagccagggagggtgccaagtttcctattaagtggacagcaccagaagcc
attaactatgggacattcaccatcaagtcggacgtgtggtcttttgggatcctgctgacg
gagattgtcactcatggtcgcatcccttacccagggatgaccaatcctgaggtgattcag
aacttggagcgaggctaccgcatggtacgacctgacaactgcccggaggagttgtaccag
cttatgatgctgtgctggaaggagcgcccggaagaccggcccacctttgactacctgcgc
agcgtgttggaggacttcttcacagccacggagggccagtaccaaccccaaccctga
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