Bubalus bubalis (water buffalo): 102408502
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Entry
102408502 CDS
T05912
Symbol
MAP3K5
Name
(RefSeq) mitogen-activated protein kinase kinase kinase 5 isoform X2
KO
K04426
mitogen-activated protein kinase kinase kinase 5 [EC:
2.7.11.25
]
Organism
bbub
Bubalus bubalis (water buffalo)
Pathway
bbub01524
Platinum drug resistance
bbub04010
MAPK signaling pathway
bbub04071
Sphingolipid signaling pathway
bbub04141
Protein processing in endoplasmic reticulum
bbub04210
Apoptosis
bbub04530
Tight junction
bbub04668
TNF signaling pathway
bbub04714
Thermogenesis
bbub04722
Neurotrophin signaling pathway
bbub04932
Non-alcoholic fatty liver disease
bbub04936
Alcoholic liver disease
bbub05010
Alzheimer disease
bbub05012
Parkinson disease
bbub05014
Amyotrophic lateral sclerosis
bbub05016
Huntington disease
bbub05017
Spinocerebellar ataxia
bbub05022
Pathways of neurodegeneration - multiple diseases
bbub05208
Chemical carcinogenesis - reactive oxygen species
bbub05417
Lipid and atherosclerosis
bbub05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
bbub00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
102408502 (MAP3K5)
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
102408502 (MAP3K5)
04668 TNF signaling pathway
102408502 (MAP3K5)
04071 Sphingolipid signaling pathway
102408502 (MAP3K5)
09140 Cellular Processes
09143 Cell growth and death
04210 Apoptosis
102408502 (MAP3K5)
09144 Cellular community - eukaryotes
04530 Tight junction
102408502 (MAP3K5)
09150 Organismal Systems
09156 Nervous system
04722 Neurotrophin signaling pathway
102408502 (MAP3K5)
09159 Environmental adaptation
04714 Thermogenesis
102408502 (MAP3K5)
09160 Human Diseases
09161 Cancer: overview
05208 Chemical carcinogenesis - reactive oxygen species
102408502 (MAP3K5)
09164 Neurodegenerative disease
05010 Alzheimer disease
102408502 (MAP3K5)
05012 Parkinson disease
102408502 (MAP3K5)
05014 Amyotrophic lateral sclerosis
102408502 (MAP3K5)
05016 Huntington disease
102408502 (MAP3K5)
05017 Spinocerebellar ataxia
102408502 (MAP3K5)
05022 Pathways of neurodegeneration - multiple diseases
102408502 (MAP3K5)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
102408502 (MAP3K5)
05418 Fluid shear stress and atherosclerosis
102408502 (MAP3K5)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
102408502 (MAP3K5)
04932 Non-alcoholic fatty liver disease
102408502 (MAP3K5)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
102408502 (MAP3K5)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
bbub01001
]
102408502 (MAP3K5)
Enzymes [BR:
bbub01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.25 mitogen-activated protein kinase kinase kinase
102408502 (MAP3K5)
Protein kinases [BR:
bbub01001
]
Serine/threonine kinases: STE group
STE11 family
102408502 (MAP3K5)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
MAP3K_TRAF_bd
Pkinase
HisK-N-like
PK_Tyr_Ser-Thr
ASK_PH
TPR-S
DRHyd-ASK
FPP
Kinase-like
Pkinase_fungal
Motif
Other DBs
NCBI-GeneID:
102408502
NCBI-ProteinID:
XP_006052330
LinkDB
All DBs
Position
10:29287627..29514263
Genome browser
AA seq
1366 aa
AA seq
DB search
MSAEAGEGITFSVPPFAEGGSYRRGGAATAAEGEENQLPPPPPGSFWNVESAAAPGAGCP
SATSGSSATRCRGNSGGGGGRRTTVAYVINEASQGQLVVAESEALQCLREACETVGAALE
TLHFGKLDFGETAVLDRFYNADIAVVEMSDAFRQPSLFYHLGVRESFSMANNIILYCDTN
SDSLQSLKEIICQKNTMCTGNYTFIPYMITPHNKVYCCDSSLMKGLTELMQPNFELLLGP
ICLPLVDRFIQLLKVAQASSSQYFRESILNDIRKARNLYTGKELAAELARIRQRVDNIEV
LTADIVINLLLSYRDIQDYDSIVKLVETLEKLPTFDLASHHHVKFHYAFALNRRNLPGDR
AKALDIMIPLVQNEEQVASDMYCLVGRIYKDMFLDSNFMDTESRDHGASWFKKAFESEPT
LQSGINYAVLLLASGHQFESSFELRKVGVKLSSLLGKKGNLEKLQSYWEVGFFLGASVLA
NDHLRVIQASEKLFKLKTPAWYLKSIVETILIYKHFVKLTSEQPVAKQELVDFWMDFLVE
ATKTDVTVVRFPVLILEPTKIYQPSYLSINNEAEEKTISIWHVLPDDKKGIHEWNFSASS
VRGVSISKFEERCCFLYVLHNSDDFQIYFCTELHCKKFFEMVNTITEEKGKNTEEGDCEG
DSLEYDYEYDENGDRVVLGKGTYGIVYAGRDLSNQVRIAIKEIPERDSRYSQPLHEEIAL
HKHLKHKNIVQYLGSFSENGFIKIFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQIL
EGLKYLHDNQIVHRDIKGDNVLINTYSGVLKISDFGTSKRLAGINPCTETFTGTLQYMAP
EIIDKGPRGYGKAADIWSLGCTIIEMATGKPPFYELGEPQAAMFKVGMFKVHPEIPESMS
AEAKAFILKCFEPDPDKRDCANDLLMDEFLKVSSKKKKTQPKLSALSAGSNEYLRSISLP
VPVLVEDTSSSSEYGSVSPDTELKVDPFSFKTRAKSCGEKDVKGIRTLFLGIPDENFEDH
SAPPSPEEKDSGFFMLRKDSERRATLHRILTEDQDKVVRNLMESLAQGAEEPKLKWEHIT
TLVASLREFVRSTDRKIIATTLSKLKLELDFDSHGISQVQVVLFGFQDAVNKVLRNHNIK
PHWMFALDSIIRKAVQTAITILVPELRPHFSLASESDTADQEDLDADGDHDERPSNQTVR
RPHAVLEDAVATSGVSTLSSTVSHDSQSAHRSLNVQLGRMKIETNRLLEELVQKEKELQA
LLHQAIEEKDQEIKHLKLKSQPIDVPGLPGCHSSSPGTNTEDSELTDWLRENGADEDTIS
LFLAEDYSLMDVLYYVTRDDLKCLRLRGGMLCTLWKAITDFRDKQA
NT seq
4101 nt
NT seq
+upstream
nt +downstream
nt
atgagcgcggaggcgggcgagggcatcactttctccgtgccacccttcgccgagggcggc
agctaccgtaggggaggagcggcgacggcggccgagggcgaggagaaccagctgccaccg
ccgccaccgggcagcttctggaacgtggaaagtgccgccgctcccggcgccgggtgtccc
agtgctacctccgggagcagcgccacccggtgccggggcaactctgggggcggaggcggc
cgacggaccacggtggcctatgtcatcaacgaggcgagccaggggcagctggtggtggcc
gagagcgaggccctgcagtgcctgcgggaggcgtgcgagacggtgggcgccgccctggag
accctgcattttgggaaactggactttggggaaactgcggtgctggaccgattttacaat
gcagatatcgccgtggtggagatgagtgatgccttccgacaaccatccttattttaccac
ctcggagtgagagaaagtttcagcatggccaacaacatcatcctctactgtgatactaat
tcagactctctgcagtcactgaaggagatcatttgccagaagaatactatgtgcactggg
aactacacgtttattccttacatgataacgccgcacaacaaggtctactgctgtgatagc
agcctcatgaagggcttgactgagctcatgcagccgaactttgagctgcttctgggaccc
atctgcttacctcttgtggatcgtttcattcagcttttgaaggtggcacaagcaagttcc
agccagtatttccgggagtctatactcaacgatatcaggaaagctcgtaacttatatact
ggcaaagaattggcagctgaattggcaagaattcgacagcgagtggataatattgaagtc
ttgacagcagatattgtcataaatctgttactttcatatagagatatccaggactatgat
tctattgtgaagctggtagagactttagaaaagcttccaacatttgatttggcctcccat
caccatgtgaagtttcattatgcctttgcactgaataggagaaacctccctggagataga
gcaaaagctcttgacattatgattcccctggtgcaaaatgaagagcaggttgcttcagat
atgtattgcctcgttggtcgaatctacaaagatatgtttttggactctaatttcatggac
actgaaagtagagaccatggagcttcttggttcaaaaaggcatttgaatcagagccaaca
ctacagtcaggaattaattatgcggtcctcctcctggcatctgggcaccagtttgaatct
tcctttgagctccgaaaagttggggtgaagctaagtagtcttcttggtaaaaagggaaac
ttggaaaaactccagagctactgggaagttggatttttcctgggggccagtgtcctggcc
aatgaccacttgagagtcattcaagcatctgaaaagctttttaaactgaagacacctgca
tggtacctcaagtctatcgtagagacaattttgatatataagcattttgtgaaactgact
tcggaacagcctgtggccaaacaggaacttgtggacttctggatggatttcctggtcgag
gccacaaagacagatgtcactgtagttaggtttccagtattaatattagaaccaaccaaa
atctaccaaccttcgtatttgtctatcaacaacgaagctgaggagaagacaatatctatt
tggcatgtgcttcctgatgacaagaaaggtatacatgagtggaattttagtgcttcttct
gtcaggggtgtgagtatttctaaatttgaagaacgatgctgttttctgtatgtgcttcac
aattctgacgatttccaaatctatttctgtacagaacttcattgtaaaaagttttttgaa
atggtgaacaccattactgaagagaaggggaaaaacacggaggaaggagattgtgaaggt
gactccctggagtatgactatgaatacgatgaaaatggtgacagagtcgttttaggaaaa
ggcacttatgggatagtttatgcaggtcgagatctgagcaaccaagtcagaatcgccatt
aaggaaatcccagagagagacagcagatactctcagcccctgcatgaagaaatagccttg
cataagcatctgaagcacaaaaatattgtccagtatctgggctctttcagtgaaaatggt
ttcattaaaatcttcatggagcaggtcccaggaggaagtctttctgctctccttcgttcc
aaatggggcccactgaaagacaatgagcaaacaatcggcttttatacaaagcaaatactg
gaaggattaaaatacctccatgataatcagatagttcaccgggatataaagggtgacaat
gtgttgattaatacctatagcggtgttctcaagatttctgattttggaacatcaaagagg
cttgctggcataaatccatgtactgaaacttttactggtaccctccagtatatggcacca
gaaataatagataaaggaccaagaggctatggaaaggcagcagacatttggtctctgggc
tgcacgatcattgaaatggccactggaaaaccacccttttatgaactgggggaaccacaa
gcagctatgttcaaggtggggatgtttaaagtccacccagagatcccagagtccatgtca
gcagaggccaaggcattcatattgaagtgtttcgaaccagaccctgacaagagagactgt
gctaacgacttgcttatggatgagttcttaaaagtttcaagcaaaaagaaaaagacacaa
cctaagctttcagctctttcagctggatcgaatgagtacctcaggagtatctccttgcca
gtgccagtcctggtagaggacacgagcagcagcagcgagtacggctcagtttcccccgac
acagagttgaaggtggaccccttctctttcaaaacaagagccaagtcctgtggagaaaag
gatgtcaaaggcatccggacgctgtttctgggcatccctgatgaaaattttgaagaccac
agtgctccaccttctccagaagaaaaagattccggattctttatgctgaggaaggacagt
gagagacgggccacgcttcacaggattctgacggaagaccaagacaaagttgtgagaaac
ttaatggaatccttggctcagggggctgaagaacctaaactgaaatgggaacacatcaca
actctcgtcgcaagcctcagagaatttgtgaggtccacggaccgaaagatcatagccacc
accctgtccaagctgaagctggagctggacttcgacagccacgggatcagtcaggtccag
gtggtgctctttggtttccaagatgctgtcaataaagttcttcggaatcataacatcaag
ccacactggatgtttgccttagacagtatcatccgaaaggcggtacagacagctattacc
attctggttccagaactgaggccgcatttcagccttgcatctgagagtgatactgccgat
caagaagacttggatgcagacggtgaccatgacgaacggccttcaaatcaaactgtccga
agacctcatgcagtgcttgaagacgcggtggccacctcaggggtgagcacgctcagttct
actgtatcccatgactcccagagtgctcaccgatcactgaatgtacaacttggaaggatg
aaaatagaaacaaatagattactggaagaattggttcagaaagagaaagaattacaagca
ctccttcatcaagctattgaagagaaagaccaagaaattaaacacctgaagcttaagtcc
caaccaatagatgttcctgggttgcctggttgtcactccagttctcctggcacaaacacc
gaagattcggaacttactgactggctgagagagaacggagctgatgaagacactataagt
ctgtttttggctgaggattattcattaatggatgttctctactatgttacacgtgatgat
ttaaaatgcctgagactaaggggcgggatgctgtgcacactgtggaaagccatcactgac
ttccgagacaaacaggcttga
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