KEGG   Bubalus bubalis (water buffalo): 102412787
Entry
102412787         CDS       T05912                                 
Symbol
CDK4
Name
(RefSeq) cyclin-dependent kinase 4
  KO
K02089  cyclin-dependent kinase 4 [EC:2.7.11.22]
Organism
bbub  Bubalus bubalis (water buffalo)
Pathway
bbub01522  Endocrine resistance
bbub04110  Cell cycle
bbub04115  p53 signaling pathway
bbub04151  PI3K-Akt signaling pathway
bbub04218  Cellular senescence
bbub04530  Tight junction
bbub04660  T cell receptor signaling pathway
bbub04933  AGE-RAGE signaling pathway in diabetic complications
bbub04934  Cushing syndrome
bbub05160  Hepatitis C
bbub05162  Measles
bbub05163  Human cytomegalovirus infection
bbub05164  Influenza A
bbub05165  Human papillomavirus infection
bbub05166  Human T-cell leukemia virus 1 infection
bbub05167  Kaposi sarcoma-associated herpesvirus infection
bbub05169  Epstein-Barr virus infection
bbub05200  Pathways in cancer
bbub05203  Viral carcinogenesis
bbub05212  Pancreatic cancer
bbub05214  Glioma
bbub05218  Melanoma
bbub05219  Bladder cancer
bbub05220  Chronic myeloid leukemia
bbub05222  Small cell lung cancer
bbub05223  Non-small cell lung cancer
bbub05224  Breast cancer
bbub05225  Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:bbub00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    102412787 (CDK4)
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    102412787 (CDK4)
   04115 p53 signaling pathway
    102412787 (CDK4)
   04218 Cellular senescence
    102412787 (CDK4)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    102412787 (CDK4)
 09150 Organismal Systems
  09151 Immune system
   04660 T cell receptor signaling pathway
    102412787 (CDK4)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    102412787 (CDK4)
   05203 Viral carcinogenesis
    102412787 (CDK4)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    102412787 (CDK4)
   05225 Hepatocellular carcinoma
    102412787 (CDK4)
   05214 Glioma
    102412787 (CDK4)
   05220 Chronic myeloid leukemia
    102412787 (CDK4)
   05218 Melanoma
    102412787 (CDK4)
   05219 Bladder cancer
    102412787 (CDK4)
   05224 Breast cancer
    102412787 (CDK4)
   05222 Small cell lung cancer
    102412787 (CDK4)
   05223 Non-small cell lung cancer
    102412787 (CDK4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    102412787 (CDK4)
   05160 Hepatitis C
    102412787 (CDK4)
   05164 Influenza A
    102412787 (CDK4)
   05162 Measles
    102412787 (CDK4)
   05163 Human cytomegalovirus infection
    102412787 (CDK4)
   05167 Kaposi sarcoma-associated herpesvirus infection
    102412787 (CDK4)
   05169 Epstein-Barr virus infection
    102412787 (CDK4)
   05165 Human papillomavirus infection
    102412787 (CDK4)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    102412787 (CDK4)
   04934 Cushing syndrome
    102412787 (CDK4)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    102412787 (CDK4)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:bbub01001]
    102412787 (CDK4)
Enzymes [BR:bbub01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.22  cyclin-dependent kinase
     102412787 (CDK4)
Protein kinases [BR:bbub01001]
 Serine/threonine kinases: CMGC group
  CDK family
   102412787 (CDK4)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr APH Kdo ABC1 Haspin_kinase Kinase-like
Other DBs
NCBI-GeneID: 102412787
NCBI-ProteinID: XP_006077980
LinkDB
Position
4:complement(64700293..64703276)
AA seq 303 aa
MATSRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGAGGGLPISTVREVALL
RRLEAFEHPNVVRLMDVCATARTDRETKVTLVFEHVDQDLRTYLDKAPPPGLPVETIKDL
MRQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQMALTPVVVTLWY
RAPEVLLQSTYATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPEDDWPR
DVSLPRGAFSPRGPRPVQSVVPELEESGAQLLLEMLTFNPHKRISAFRALQHSYLHKAEG
DAE
NT seq 912 nt   +upstreamnt  +downstreamnt
atggctacctcccgatatgagccagtggctgagattggtgtcggtgcctatgggacagtg
tacaaggcccgtgatccccacagtggccactttgtggccctcaagagtgtaagagtcccc
aatggaggaggtgctggagggggcctgcccatcagcaccgttcgggaggtggccttactg
cggcgtctggaggcttttgagcatcccaatgttgtcaggctcatggatgtctgtgcaaca
gcccgaactgaccgggagaccaaagtgaccctggtgtttgagcatgtggaccaagacctc
aggacctatctggacaaggcacccccaccaggcttgccagtggagaccataaaggatctg
atgcgccaatttctaagaggcctggatttccttcatgccaactgcatcgttcaccgagac
ctgaagccagagaacattctggtgacaagtggtgggacagtcaagctggctgactttggc
ctggccagaatctacagctaccagatggcacttacacctgtggttgttacactctggtat
cgtgctccagaagttcttttgcagtctacgtatgcaacacccgtggacatgtggagcgtt
ggctgtatcttcgcagagatgtttcgtcgaaagcctctcttctgtggaaactctgaagct
gaccagttaggcaaaatctttgacctgattggactgcccccagaggatgactggccccga
gatgtctctctaccccgaggagccttttcccccagagggccccgcccagtgcagtcggtg
gtccctgagctggaggaatctggagcacagctgctgctggagatgctgacttttaaccca
cacaagcgaatctctgccttccgagccctgcagcactcttatctacacaaggcagaaggt
gacgcagagtga

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