Bubalus bubalis (water buffalo): 102412929 Help Entry 102412929         CDS       T05912                                  Symbol CASP8 Name (RefSeq) caspase-8   KO K04398   caspase 8 [EC:3.4.22.61] Organism bbub  Bubalus bubalis (water buffalo) Pathway bbub01524   Platinum drug resistance bbub04115   p53 signaling pathway bbub04210   Apoptosis bbub04215   Apoptosis - multiple species bbub04217   Necroptosis bbub04620   Toll-like receptor signaling pathway bbub04621   NOD-like receptor signaling pathway bbub04622   RIG-I-like receptor signaling pathway bbub04623   Cytosolic DNA-sensing pathway bbub04625   C-type lectin receptor signaling pathway bbub04657   IL-17 signaling pathway bbub04668   TNF signaling pathway bbub04932   Non-alcoholic fatty liver disease bbub04936   Alcoholic liver disease bbub05010   Alzheimer disease bbub05016   Huntington disease bbub05022   Pathways of neurodegeneration - multiple diseases bbub05132   Salmonella infection bbub05134   Legionellosis bbub05142   Chagas disease bbub05145   Toxoplasmosis bbub05152   Tuberculosis bbub05160   Hepatitis C bbub05161   Hepatitis B bbub05162   Measles bbub05163   Human cytomegalovirus infection bbub05164   Influenza A bbub05165   Human papillomavirus infection bbub05167   Kaposi sarcoma-associated herpesvirus infection bbub05168   Herpes simplex virus 1 infection bbub05169   Epstein-Barr virus infection bbub05170   Human immunodeficiency virus 1 infection bbub05200   Pathways in cancer bbub05203   Viral carcinogenesis bbub05416   Viral myocarditis bbub05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:bbub00001]  09130 Environmental Information Processing   09132 Signal transduction    04668 TNF signaling pathway     102412929 (CASP8)  09140 Cellular Processes   09143 Cell growth and death    04210 Apoptosis     102412929 (CASP8)    04215 Apoptosis - multiple species     102412929 (CASP8)    04217 Necroptosis     102412929 (CASP8)    04115 p53 signaling pathway     102412929 (CASP8)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     102412929 (CASP8)    04621 NOD-like receptor signaling pathway     102412929 (CASP8)    04622 RIG-I-like receptor signaling pathway     102412929 (CASP8)    04623 Cytosolic DNA-sensing pathway     102412929 (CASP8)    04625 C-type lectin receptor signaling pathway     102412929 (CASP8)    04657 IL-17 signaling pathway     102412929 (CASP8)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     102412929 (CASP8)    05203 Viral carcinogenesis     102412929 (CASP8)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     102412929 (CASP8)    05161 Hepatitis B     102412929 (CASP8)    05160 Hepatitis C     102412929 (CASP8)    05164 Influenza A     102412929 (CASP8)    05162 Measles     102412929 (CASP8)    05168 Herpes simplex virus 1 infection     102412929 (CASP8)    05163 Human cytomegalovirus infection     102412929 (CASP8)    05167 Kaposi sarcoma-associated herpesvirus infection     102412929 (CASP8)    05169 Epstein-Barr virus infection     102412929 (CASP8)    05165 Human papillomavirus infection     102412929 (CASP8)   09171 Infectious disease: bacterial    05132 Salmonella infection     102412929 (CASP8)    05134 Legionellosis     102412929 (CASP8)    05152 Tuberculosis     102412929 (CASP8)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     102412929 (CASP8)    05142 Chagas disease     102412929 (CASP8)   09164 Neurodegenerative disease    05010 Alzheimer disease     102412929 (CASP8)    05016 Huntington disease     102412929 (CASP8)    05022 Pathways of neurodegeneration - multiple diseases     102412929 (CASP8)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     102412929 (CASP8)    05416 Viral myocarditis     102412929 (CASP8)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     102412929 (CASP8)    04932 Non-alcoholic fatty liver disease     102412929 (CASP8)   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     102412929 (CASP8)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:bbub01002]     102412929 (CASP8) Enzymes [BR:bbub01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.61  caspase-8      102412929 (CASP8) Peptidases and inhibitors [BR:bbub01002]  Cysteine peptidases   Family C14: caspase family    102412929 (CASP8) SSDB OrthologParalogGFIT Motif Pfam:  Peptidase_C14 DED Motif Other DBs NCBI-GeneID:  102412929 NCBI-ProteinID:  XP_044793152 LinkDB All DBs Position 2:141982022..142006184 Genome browser AA seq 486 aa AA seqDB search MALTQCLYNIGEQLGSDDLAALKFLSRDHIPYRKQEPIKDALMLFQRLQEKRMLEENNLS FLKELLFRVNRLDLLLNYLYTSEEEMKRELQIPGRAQISAYRILLFQISEDVNKVELKDF KFFLSQEIAKCKLDDDMTLLDIFVEMEKRTILGEENLDTLKRICEQVNKSLLKKIYDYEE LRQERRMSLERDPDAFSNDMSQSLPEEGYSEMPAMSDSPGEQDSEWQTSDTVYRMTSKPR GYCLIFNNYDFSIARKQVPELHDLRDRTGTHFDAEALDKTFRDLHFEIVHYKDQTAKGIC EVLESYRKKDHKNKDCFICCILTHGNKGIIYGSDGQEASIYELTSYFTGLKCPSLIGKPK IFFIQACQGDKYQKGVAVETDSEQMEAYLEVDSSPQKRYIPDEADFLLGMATVKDYVSYR NIWNGTWYIQSLCQNLRERCPRGEDILTILTKVNFEVSKKDDKERMAKQMPQPTFTLRKK LFFPLN NT seq 1461 nt NT seq  +upstreamnt  +downstreamnt atggctctcacccaatgtctctataatattggggagcagctgggcagtgacgacctggct gccctcaagttcctaagccgggaccacatcccatataggaagcaggaacccatcaaggat gccttgatgctattccagaggctccaagaaaagagaatgttggaggaaaacaatctgtcc ttcttgaaggagctgcttttccgagtgaatagactggatctgctgcttaactacttgtat accagcgaggaggagatgaagagggagcttcagatacccggcagggcccagatctctgcc tacaggattctgcttttccagatttcagaagatgtgaacaaagtagaattgaaggacttt aagttttttttgagccaggagattgccaaatgtaagctggatgatgacatgactttgctt gatattttcgtggagatggagaagaggaccatcctaggggaagagaacttggacaccctg aaaagaatctgtgagcaggtcaacaagagcttgctgaagaaaatctatgattatgaagaa ttaagacaagagagaagaatgagccttgaaagagatccagatgcattttcaaatgatatg tcacaatcgcttccagaggagggctactctgagatgccggccatgtcagactctccagga gaacaggacagtgagtggcagacatctgacacagtttaccgaatgacaagcaaacctcgg ggatactgtttgatctttaacaattatgattttagcatagcacggaagcaggtgcctgaa cttcacgaccttagggataggactggaacacactttgatgcagaggctttggataagacc tttcgtgaccttcattttgagatagtgcactacaaagaccaaacagcaaagggaatctgt gaggttctagaatcctaccggaagaaggaccacaaaaacaaagactgcttcatctgctgc atcctcacccacggaaacaagggcatcatctatggttccgatgggcaagaagcctccatc tatgagctgacctcttacttcactggcttaaaatgcccttcccttattggcaaacccaaa atcttttttattcaggcttgtcaaggggacaagtaccagaaaggtgtagctgttgagacc gactcagaacagatggaagcctatttagaggtggactcatcacctcagaagagatatatc ccagatgaggctgactttctgctggggatggccactgtgaaagactatgtttcctaccga aacatctggaatgggacctggtatatccaatcactttgccagaatctgagagaaagatgt cctaggggtgaagacattctgaccatcctaaccaaggtgaactttgaagtaagcaaaaag gatgacaaggaacgtatggccaaacagatgccacaacctactttcacactgcgaaaaaaa ctcttctttcctcttaattga

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