KEGG   Bubalus bubalis (water buffalo): 102413660
Entry
102413660         CDS       T05912                                 
Symbol
TGFB1
Name
(RefSeq) transforming growth factor beta-1 proprotein isoform X2
  KO
K13375  transforming growth factor beta-1
Organism
bbub  Bubalus bubalis (water buffalo)
Pathway
bbub04010  MAPK signaling pathway
bbub04060  Cytokine-cytokine receptor interaction
bbub04068  FoxO signaling pathway
bbub04110  Cell cycle
bbub04148  Efferocytosis
bbub04218  Cellular senescence
bbub04350  TGF-beta signaling pathway
bbub04380  Osteoclast differentiation
bbub04390  Hippo signaling pathway
bbub04518  Integrin signaling
bbub04659  Th17 cell differentiation
bbub04672  Intestinal immune network for IgA production
bbub04926  Relaxin signaling pathway
bbub04932  Non-alcoholic fatty liver disease
bbub04933  AGE-RAGE signaling pathway in diabetic complications
bbub05140  Leishmaniasis
bbub05142  Chagas disease
bbub05144  Malaria
bbub05145  Toxoplasmosis
bbub05146  Amoebiasis
bbub05152  Tuberculosis
bbub05161  Hepatitis B
bbub05166  Human T-cell leukemia virus 1 infection
bbub05200  Pathways in cancer
bbub05205  Proteoglycans in cancer
bbub05210  Colorectal cancer
bbub05211  Renal cell carcinoma
bbub05212  Pancreatic cancer
bbub05220  Chronic myeloid leukemia
bbub05225  Hepatocellular carcinoma
bbub05226  Gastric cancer
bbub05321  Inflammatory bowel disease
bbub05323  Rheumatoid arthritis
bbub05410  Hypertrophic cardiomyopathy
bbub05414  Dilated cardiomyopathy
bbub05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:bbub00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    102413660 (TGFB1)
   04350 TGF-beta signaling pathway
    102413660 (TGFB1)
   04390 Hippo signaling pathway
    102413660 (TGFB1)
   04068 FoxO signaling pathway
    102413660 (TGFB1)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    102413660 (TGFB1)
   04518 Integrin signaling
    102413660 (TGFB1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    102413660 (TGFB1)
  09143 Cell growth and death
   04110 Cell cycle
    102413660 (TGFB1)
   04218 Cellular senescence
    102413660 (TGFB1)
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    102413660 (TGFB1)
   04672 Intestinal immune network for IgA production
    102413660 (TGFB1)
  09152 Endocrine system
   04926 Relaxin signaling pathway
    102413660 (TGFB1)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    102413660 (TGFB1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    102413660 (TGFB1)
   05205 Proteoglycans in cancer
    102413660 (TGFB1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    102413660 (TGFB1)
   05212 Pancreatic cancer
    102413660 (TGFB1)
   05225 Hepatocellular carcinoma
    102413660 (TGFB1)
   05226 Gastric cancer
    102413660 (TGFB1)
   05220 Chronic myeloid leukemia
    102413660 (TGFB1)
   05211 Renal cell carcinoma
    102413660 (TGFB1)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    102413660 (TGFB1)
   05161 Hepatitis B
    102413660 (TGFB1)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    102413660 (TGFB1)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    102413660 (TGFB1)
   05144 Malaria
    102413660 (TGFB1)
   05145 Toxoplasmosis
    102413660 (TGFB1)
   05140 Leishmaniasis
    102413660 (TGFB1)
   05142 Chagas disease
    102413660 (TGFB1)
  09163 Immune disease
   05323 Rheumatoid arthritis
    102413660 (TGFB1)
   05321 Inflammatory bowel disease
    102413660 (TGFB1)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    102413660 (TGFB1)
   05414 Dilated cardiomyopathy
    102413660 (TGFB1)
   05415 Diabetic cardiomyopathy
    102413660 (TGFB1)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    102413660 (TGFB1)
   04933 AGE-RAGE signaling pathway in diabetic complications
    102413660 (TGFB1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03110 Chaperones and folding catalysts [BR:bbub03110]
    102413660 (TGFB1)
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:bbub04052]
    102413660 (TGFB1)
   00536 Glycosaminoglycan binding proteins [BR:bbub00536]
    102413660 (TGFB1)
Chaperones and folding catalysts [BR:bbub03110]
 Intramolecular chaperones
  Others
   102413660 (TGFB1)
Cytokines and neuropeptides [BR:bbub04052]
 Cytokines
  Transforming growth factors (RSTK binding)
   102413660 (TGFB1)
Glycosaminoglycan binding proteins [BR:bbub00536]
 Heparan sulfate / Heparin
  Growth factors/receptors
   102413660 (TGFB1)
SSDB
Motif
Pfam: TGFb_propeptide TGF_beta
Other DBs
NCBI-GeneID: 102413660
NCBI-ProteinID: XP_025124932
LinkDB
Position
18:complement(49828878..49852896)
AA seq 409 aa
MPPSGLRLLPLLLPLLWLLMLTPGRPVAGLSTCKTIDMELVKRKRIEAIRGQILSKLRLA
SPPSQGDVPPGPLPEAILALYNSTRDRVAGESAETEPEPEADYYAKEVTRVLMVEYGNKI
YDKMKSSSHSIYMFFNTSELREAVPEPVLLSRAELRLLRLKLKVEQHVELYQKYSNNSWR
YLSNRLLAPSDSPEWLSFDVTGVVRQWLTRREEIEGFRLSAHCSCDSKDNTLQVDINGFS
SGRRGDLATIHGMNRPFLLLMATPLERAQHLHSSRHRRALDTNYCFSSTEKNCCVRQLYI
DFRKDLGWKWIHEPKGYHANFCLGPCPYIWSLDTQYSKVAWESYLWGCTGEMNNQHGTGA
QHRPLHTRHHPTSDDFLQHEEVCGPGDTSIRPPYHLPGQECFGGLSTWS
NT seq 1230 nt   +upstreamnt  +downstreamnt
atgccgccctcggggctgcggctgctgccgctgctgctgccgctgctgtggctactaatg
ctgacgcctggccggccggtcgccggactgtccacctgcaagaccatcgacatggagcta
gtgaagcggaagcgcatcgaggccatccgcggccagattttgtccaagcttcggctcgcc
agccccccgagccagggggatgtgccacccggcccgctgcccgaggccatactggccctt
tacaacagtacccgcgaccgggtggccggggaaagtgccgaaacggagcctgagccagag
gcggactactacgccaaggaggtcacccgcgtgctaatggtggaatacggcaacaaaatc
tatgacaaaatgaagtctagctcgcacagcatatatatgttcttcaacacgtctgagctc
cgggaagcggtgcccgaacctgtgttgctctctcgggcagagctgcgcctgctgaggctc
aagttaaaagtggagcagcacgtggagctgtaccagaaatatagcaacaattcctggcgc
tacctcagcaaccggctgctcgcccccagcgactcaccggagtggctgtcctttgacgtc
actggagttgtgcggcagtggctgacccgcagagaggaaatagagggctttcgcctcagt
gcccactgttcctgtgacagtaaagataacactcttcaagtggacattaacgggttcagt
tccggccgccggggtgacctcgccaccattcacggcatgaaccggcccttcctgctcctc
atggccacccctctggagagggcccagcacctgcacagctcccgccaccgccgagccctg
gacaccaactactgcttcagctccacagaaaagaactgctgtgttcgtcagctctacatt
gacttccggaaggacctgggctggaagtggattcacgaacccaaggggtaccacgccaat
ttctgcctggggccctgcccttacatctggagcctggacacacagtacagcaaggtggcc
tgggaatcttatctctggggttgtactggagaaatgaacaaccagcacggcacgggcgcc
cagcacaggcccctccacaccaggcatcaccctaccagtgatgacttcttgcagcatgag
gaggtctgcggtcctggggacacttcaatcaggccgccataccatctacctggacaggaa
tgtttcggtggtctatcaacgtggagctga

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