Bubalus bubalis (water buffalo): 102415323 Help Entry 102415323         CDS       T05912                                  Symbol ADCY1 Name (RefSeq) adenylate cyclase type 1   KO K08041   adenylate cyclase 1 [EC:4.6.1.1] Organism bbub  Bubalus bubalis (water buffalo) Pathway bbub00230   Purine metabolism bbub01100   Metabolic pathways bbub01522   Endocrine resistance bbub04015   Rap1 signaling pathway bbub04020   Calcium signaling pathway bbub04022   cGMP-PKG signaling pathway bbub04024   cAMP signaling pathway bbub04062   Chemokine signaling pathway bbub04072   Phospholipase D signaling pathway bbub04081   Hormone signaling bbub04082   Neuroactive ligand signaling bbub04114   Oocyte meiosis bbub04211   Longevity regulating pathway bbub04213   Longevity regulating pathway - multiple species bbub04261   Adrenergic signaling in cardiomyocytes bbub04270   Vascular smooth muscle contraction bbub04371   Apelin signaling pathway bbub04540   Gap junction bbub04611   Platelet activation bbub04713   Circadian entrainment bbub04714   Thermogenesis bbub04720   Long-term potentiation bbub04723   Retrograde endocannabinoid signaling bbub04724   Glutamatergic synapse bbub04725   Cholinergic synapse bbub04727   GABAergic synapse bbub04750   Inflammatory mediator regulation of TRP channels bbub04911   Insulin secretion bbub04912   GnRH signaling pathway bbub04913   Ovarian steroidogenesis bbub04914   Progesterone-mediated oocyte maturation bbub04915   Estrogen signaling pathway bbub04916   Melanogenesis bbub04918   Thyroid hormone synthesis bbub04921   Oxytocin signaling pathway bbub04923   Regulation of lipolysis in adipocytes bbub04925   Aldosterone synthesis and secretion bbub04926   Relaxin signaling pathway bbub04927   Cortisol synthesis and secretion bbub04928   Parathyroid hormone synthesis, secretion and action bbub04934   Cushing syndrome bbub04935   Growth hormone synthesis, secretion and action bbub04970   Salivary secretion bbub04971   Gastric acid secretion bbub04972   Pancreatic secretion bbub04976   Bile secretion bbub05032   Morphine addiction bbub05142   Chagas disease bbub05146   Amoebiasis bbub05163   Human cytomegalovirus infection bbub05166   Human T-cell leukemia virus 1 infection bbub05200   Pathways in cancer bbub05207   Chemical carcinogenesis - receptor activation bbub05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:bbub00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     102415323 (ADCY1)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     102415323 (ADCY1)    04371 Apelin signaling pathway     102415323 (ADCY1)    04020 Calcium signaling pathway     102415323 (ADCY1)    04072 Phospholipase D signaling pathway     102415323 (ADCY1)    04024 cAMP signaling pathway     102415323 (ADCY1)    04022 cGMP-PKG signaling pathway     102415323 (ADCY1)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     102415323 (ADCY1)    04081 Hormone signaling     102415323 (ADCY1)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     102415323 (ADCY1)   09144 Cellular community - eukaryotes    04540 Gap junction     102415323 (ADCY1)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     102415323 (ADCY1)    04062 Chemokine signaling pathway     102415323 (ADCY1)   09152 Endocrine system    04911 Insulin secretion     102415323 (ADCY1)    04923 Regulation of lipolysis in adipocytes     102415323 (ADCY1)    04912 GnRH signaling pathway     102415323 (ADCY1)    04913 Ovarian steroidogenesis     102415323 (ADCY1)    04915 Estrogen signaling pathway     102415323 (ADCY1)    04914 Progesterone-mediated oocyte maturation     102415323 (ADCY1)    04921 Oxytocin signaling pathway     102415323 (ADCY1)    04926 Relaxin signaling pathway     102415323 (ADCY1)    04935 Growth hormone synthesis, secretion and action     102415323 (ADCY1)    04918 Thyroid hormone synthesis     102415323 (ADCY1)    04928 Parathyroid hormone synthesis, secretion and action     102415323 (ADCY1)    04916 Melanogenesis     102415323 (ADCY1)    04925 Aldosterone synthesis and secretion     102415323 (ADCY1)    04927 Cortisol synthesis and secretion     102415323 (ADCY1)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     102415323 (ADCY1)    04270 Vascular smooth muscle contraction     102415323 (ADCY1)   09154 Digestive system    04970 Salivary secretion     102415323 (ADCY1)    04971 Gastric acid secretion     102415323 (ADCY1)    04972 Pancreatic secretion     102415323 (ADCY1)    04976 Bile secretion     102415323 (ADCY1)   09156 Nervous system    04724 Glutamatergic synapse     102415323 (ADCY1)    04727 GABAergic synapse     102415323 (ADCY1)    04725 Cholinergic synapse     102415323 (ADCY1)    04720 Long-term potentiation     102415323 (ADCY1)    04723 Retrograde endocannabinoid signaling     102415323 (ADCY1)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     102415323 (ADCY1)   09149 Aging    04211 Longevity regulating pathway     102415323 (ADCY1)    04213 Longevity regulating pathway - multiple species     102415323 (ADCY1)   09159 Environmental adaptation    04713 Circadian entrainment     102415323 (ADCY1)    04714 Thermogenesis     102415323 (ADCY1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     102415323 (ADCY1)    05207 Chemical carcinogenesis - receptor activation     102415323 (ADCY1)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     102415323 (ADCY1)    05163 Human cytomegalovirus infection     102415323 (ADCY1)   09174 Infectious disease: parasitic    05146 Amoebiasis     102415323 (ADCY1)    05142 Chagas disease     102415323 (ADCY1)   09165 Substance dependence    05032 Morphine addiction     102415323 (ADCY1)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     102415323 (ADCY1)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     102415323 (ADCY1)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     102415323 (ADCY1) Enzymes [BR:bbub01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      102415323 (ADCY1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Guanylate_cyc AC_N Adcy_cons_dom DUF7246 Motif Other DBs NCBI-GeneID:  102415323 NCBI-ProteinID:  XP_006051342 LinkDB All DBs Position 8:complement(75698382..75803541) Genome browser AA seq 1134 aa AA seqDB search MAGAPRGRGGGGGGGGAGESGGAERAAGPGGRRGLRACDEEFACPELEALFRGYTLRLEQ AATLKALAVLSLLAGALALAELLGAPGPAPGLAKGSHPVHCVLFLALLVVTNVRSLQVPQ LQQVGQLALLFSLTFALLCCPFALGGPAGAHAGAAAVPATADQGVWQLLLVTFVSYALLP VRSLLAIGFGLVVAASHLLVTATLVPAKRPRLWRTLGANALLFLGVNMYGVFVRILAERA QRKAFLQARNCIEDRLRLEDENEKQERLLMSLLPRNVAMEMKEDFLKPPERIFHKIYIQR HDNVSILFADIVGFTGLASQCTAQELVKLLNELFGKFDELATENHCRRIKILGDCYYCVS GLTQPKTDHAHCCVEMGLDMIDTITSVAEATEVDLNMRVGLHTGRVLCGVLGLRKWQYDV WSNDVTLANVMEAAGLPGKVHITKTTLACLNGDYEVEPGHGHERNSFLKTHNIETFFIVP SHRRKIFPGLILSDIKPAKRMKFKTVCYLLVQLMHCRKMFKAEIPFSNVMTCEDDDKRRA LRTASEKLRNRSSFSTNVVQTTPGTRVNRYIGRLLEARQMELEMADLNFFTLKYKQAERE RKYHQLQDEYFTSAVVLALILAALFGLVYLLIIPQSVAVLLLLVFCICFLVACVLYLHIT RVQCFPGCLTIQIRTVLCIFIVVLIYSVAQGCVVGCLPWSWSSSPNGSLVVLSSGGRDPV LPVPPCESAPHALLCGLVGTLPLAIFLRVSSLPKMILLAVLTTSYILVLELSGYTKAMGA GAVSGRSFEPIVAILLFSCTLALHARQVDVKLRLDYLWAAQAEEERDDMEKVKLDNKRIL FNLLPAHVAQHFLMSNPRNMDLYYQSYSQVGVMFASIPNFNDFYIELDGNNMGVECLRLL NEIIADFDELMDKDFYKDLEKIKTIGSTYMAAVGLAPTAGTKAKKCISSHLSTLADFAIE MFDVLDEINYQSYNDFVLRVGINVGPVVAGVIGARRPQYDIWGNTVNVASRMDSTGVQGR IQVTEEVHRLLRRGSYRFVCRGKVSVKGKGEMLTYFLEGRTDGNGSQTRSLNSERKMYPF GRAGLQTRLAAGHPPVPPAAGLPVGPGPGALQGSGLAPGPPGQHLPPGASGKEA NT seq 3405 nt NT seq  +upstreamnt  +downstreamnt atggcgggggcgccgcgcggccgaggcggcggcggaggcggaggcggcgcgggcgagtct gggggcgccgagcgggcggcggggccgggcggccggcgcgggctgcgggcgtgcgatgag gagttcgcgtgccccgagctggaggcgctgttccgcggctacacgctgcggctggagcag gcggcgacgctgaaggcgctggccgtgctcagcctgctggcgggagcgctggccctggcc gagctgctgggcgcgccggggcccgcgcccggcctggccaagggctcgcaccccgtgcac tgcgtgctcttcctggcgctgctcgtggtcaccaacgtccgctcgctgcaggtgccccag ctgcagcaggtcggccagctcgcgctgctcttcagcctcaccttcgctctgctgtgctgt cccttcgcgctcggcggccccgccggtgcccacgccggggcggcagcggtgccggcgaca gccgatcagggagtctggcagctccttttggtcaccttcgtgtcatatgccctgctgccc gtgcgcagcctgctggccatcggcttcgggctcgtggtagccgcctcgcacttgctggtc acggctacgttggtcccagccaagcgcccacgtctctggagaacgctgggtgccaacgct ctgctcttcctcggtgtgaacatgtatggcgtcttcgtgaggatcctggctgagcgcgcc cagaggaaggccttcctgcaggcccggaactgcattgaggaccggctgaggctggaggac gagaatgagaagcaggagcggctgctcatgagcctcctgcctcggaatgttgccatggag atgaaggaggacttcctgaagccccctgagaggattttccacaagatttacatccagcgg catgacaatgtgagcatcctctttgcagacatcgtgggcttcacgggcttggcgtcacag tgcacggctcaggagctggtgaaactcctcaacgagctcttcgggaagtttgacgagctg gccacggagaaccactgccgccgcatcaagatcctgggagattgctactactgcgtgtct ggcctcactcagcccaagactgaccacgcccactgctgtgtggagatgggcctggacatg atcgacaccatcacgtccgtggctgaggccactgaggtggacttgaacatgcgtgtgggg ctgcacaccggcagggtcctctgcggggtcctgggcctgcgtaagtggcagtatgatgtg tggtccaacgacgtgaccctggccaacgtcatggaggccgctggcctgcctgggaaggtt cacatcacaaagaccaccctggcgtgcctgaacggtgactatgaggtggagccgggacac ggacacgagaggaacagttttctgaaaactcataacatcgagaccttttttattgtgccc tcacatcggcgaaagatatttccggggctgattctctcagacataaaaccggccaagagg atgaagttcaagaccgtgtgctacctgctggtgcagctcatgcactgccggaagatgttc aaggccgagatccctttctccaacgtcatgacctgtgaggacgacgacaagcggagggca ctgagaacagcctcggaaaaactcagaaaccgctcgtctttctctacaaacgttgtccaa accacccccggcacacgtgtcaacaggtacatcggccgcctcctggaagcccgccagatg gagctggagatggcagacctgaacttcttcaccctgaagtacaagcaagctgagcgagag cgaaagtaccaccagcttcaggacgagtatttcaccagcgccgtggttctggctctcatt ctggccgccttattcggccttgtctaccttctaataatcccacagagtgtggctgtcctt ctcctgctggtgttctgcatctgcttcctggtggcctgtgtcctgtacctacacatcacc cgggtccagtgttttccagggtgcctgaccatccagatccgcaccgtcttgtgcatcttc atcgtggtcttaatctactctgtggcccaaggctgtgtggtgggctgtctgccttggtcc tggagctccagtcccaacgggtccctggtggtcctgtcctctgggggccgggacccagtg ctgcctgtcccgccctgcgagtctgcgccccacgccctgctgtgcggcctcgtgggcacc ctcccgctggccatattcctgcgggtctcctccttgccaaaaatgatcctgctcgccgtg ctcaccacctcctacatcctcgtcctggagctcagcgggtacacgaaggccatgggggcc ggtgccgtctcagggcgcagcttcgagccgatcgtggccatcctgctattctcgtgcacg ctggccctgcacgcccggcaggtggatgtcaagctgcggctggactacctctgggcggcc caggcagaggaggagcgggatgacatggagaaagtgaagctggacaacaagaggattctc ttcaacctcctgccagcccacgttgcccagcacttcctaatgtccaaccctcgcaacatg gacctgtattaccagtcgtactcgcaggtgggggtcatgtttgcatccatccccaacttc aatgacttctacatcgagctggatggcaacaacatgggggtggagtgtctgcgccttctg aatgagataatcgccgactttgatgagctcatggacaaagacttttacaaggacctagag aagatcaagaccatcgggagcacgtacatggctgctgtggggctggcgcccactgctggg accaaggctaagaagtgcatctcctcccacctcagcacgttggcagattttgccatcgag atgtttgatgtcctggatgagatcaactaccagtcttataacgactttgtactccgtgtt ggcatcaacgttggccccgtggtggctggagtgatcggggctcgcaggcctcagtatgac atttgggggaacacggtcaatgtggccagtcggatggacagtaccggcgtccagggcagg atccaggtcacagaggaagttcaccggctgctgcggcggggttcctaccgcttcgtgtgc cgaggcaaagtcagcgtcaagggcaagggcgagatgctgacgtacttcctggaaggcagg accgatggaaatggatcccaaaccaggtccctgaactcagagcggaaaatgtatcctttc ggaagagctggcctccagaccagactggctgcgggtcaccccccggtacctcctgcagct ggcctcccagttggacctgggccaggggctctgcagggctcggggcttgccccaggcccc ccaggccaacacctgccccctggagcctctgggaaggaggcttag

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