Bubalus bubalis (water buffalo): 102416637 Help Entry 102416637         CDS       T05912                                  Symbol IRS1 Name (RefSeq) insulin receptor substrate 1   KO K16172   insulin receptor substrate 1 Organism bbub  Bubalus bubalis (water buffalo) Pathway bbub04022   cGMP-PKG signaling pathway bbub04068   FoxO signaling pathway bbub04081   Hormone signaling bbub04140   Autophagy - animal bbub04150   mTOR signaling pathway bbub04151   PI3K-Akt signaling pathway bbub04152   AMPK signaling pathway bbub04211   Longevity regulating pathway bbub04213   Longevity regulating pathway - multiple species bbub04722   Neurotrophin signaling pathway bbub04910   Insulin signaling pathway bbub04920   Adipocytokine signaling pathway bbub04923   Regulation of lipolysis in adipocytes bbub04930   Type II diabetes mellitus bbub04931   Insulin resistance bbub04932   Non-alcoholic fatty liver disease bbub04935   Growth hormone synthesis, secretion and action bbub04960   Aldosterone-regulated sodium reabsorption bbub05010   Alzheimer disease bbub05206   MicroRNAs in cancer bbub05415   Diabetic cardiomyopathy Brite KEGG Orthology (KO) [BR:bbub00001]  09130 Environmental Information Processing   09132 Signal transduction    04068 FoxO signaling pathway     102416637 (IRS1)    04022 cGMP-PKG signaling pathway     102416637 (IRS1)    04151 PI3K-Akt signaling pathway     102416637 (IRS1)    04152 AMPK signaling pathway     102416637 (IRS1)    04150 mTOR signaling pathway     102416637 (IRS1)   09133 Signaling molecules and interaction    04081 Hormone signaling     102416637 (IRS1)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     102416637 (IRS1)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     102416637 (IRS1)    04923 Regulation of lipolysis in adipocytes     102416637 (IRS1)    04920 Adipocytokine signaling pathway     102416637 (IRS1)    04935 Growth hormone synthesis, secretion and action     102416637 (IRS1)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     102416637 (IRS1)   09156 Nervous system    04722 Neurotrophin signaling pathway     102416637 (IRS1)   09149 Aging    04211 Longevity regulating pathway     102416637 (IRS1)    04213 Longevity regulating pathway - multiple species     102416637 (IRS1)  09160 Human Diseases   09161 Cancer: overview    05206 MicroRNAs in cancer     102416637 (IRS1)   09164 Neurodegenerative disease    05010 Alzheimer disease     102416637 (IRS1)   09166 Cardiovascular disease    05415 Diabetic cardiomyopathy     102416637 (IRS1)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     102416637 (IRS1)    04932 Non-alcoholic fatty liver disease     102416637 (IRS1)    04931 Insulin resistance     102416637 (IRS1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  IRS PH PH_11 Motif Other DBs NCBI-GeneID:  102416637 NCBI-ProteinID:  XP_006074156 LinkDB All DBs Position 2:complement(167210212..167274523) Genome browser AA seq 1236 aa AA seqDB search MASPPETDGFSDVRKVGYLRKPKSMHKRFFVLRAASEAGGPARLEYYENEKKWRHKSSAP KRSIPLESCFNINKRADSKNKHLVALYTRDEHFAIAADSEAEQDSWYQALLQLHNRAKGH HDGAAAPGAGGGGGSCSGSSGLGEAGEDLSYGDVPPGPAFKEVWQVILKPKGLGQTKNLI GIYRLCLTSKTISFVKLNSEAAAVVLQLMNIRRCGHSENFFFIEVGRSAVTGPGEFWMQV DDSVVAQNMHETILEAMRAMSDEFRPRSKSQSSSNCSNPISVPLRRHHLNNPPPSQVGLT RRSRTESITATSPASLVGGKQGSFRVRASSDGEGTMSRPASVDGSPVSPSTNRTHAHRHR GSSRLHPPLNHSRSIPMPSSRCSPSATSPVSLSSSSTSGHGSTSDCLFPRRSSASVSGSP SDGGFISSDEYGSSPCDFRSSFRSVTPDSLGHTPPARGEEELSNYICMGGKGASTLTAPN GHYILPRGGNGHRYVPAAGLGTSPALPGEEAAGAADLDNRFRKRTHSAGTSPTISHQKTP SQSSVASIEEYTEMMPAYPPGGGSGGRVPGYRHSAFVPTHSYPEEGLEMHPLERRGGHHR PDTSSLHTDDGYMPMSPGVAPVPGSRKGSGDYMPMSPKSVSAPQQIINPIRRHPQRVDPN GYMMMSPSGSCSPDIGGGPSSGGSSSGAAPSGSSYGKLWTNGVGGHHSHALPHPKLPVES GSGKLLSCAGDYMNMSPVGDSNTSSPSDCYYGPEDPQHKPVLSYYSLPRSFKHTQRPGEL EEPRHHQHIRLSTSSGRLLYTAAAEDSSSSTSSDSLGGGYCGARPEPGLPHLHHQVLQAH LPRKVDTAAQTNNRLARPTRLSLGDPKASTLPRAREQQPPPPLLLPPEPKSPGEYVNIEF GSDQPGYLSGPVASHSSPSIRCPSQLQPAPREEETGAEEYMNMDLGPGRRATWQEGVGVQ PGRVGPAPPGAASVCRPTRAVPSSRGDYMTMQMGGPRQSYVDTSPVAPISYADMRTGVVV EDASLPGATAATPSSSSTASVSSTAPPGTGELAARSALLGGPSAFTRVNLSPNRNQSAKV IRADPQGCRRRHSSETFSSTPSATRVGNTMPFGAGAAVGGSGGGSSSSAEDVKRHSSASF ENVWLRPGELGGAPKELAQVCGAAGGLENGLNYIDLDLVKDFKQRLQERPPQPQPPALPA PHQPLGSSQSGPTSRSSEDLSAYASITFQKQPEDLQ NT seq 3711 nt NT seq  +upstreamnt  +downstreamnt atggcgagccctccggagacggacggcttctcggacgtgcgcaaggtgggctacctgcgc aaacccaagagcatgcacaagcgattcttcgtgctgcgggcggccagcgaggctgggggc cctgcgcgcctcgagtactacgagaacgagaagaagtggcggcacaagtcgagcgccccc aaacgctcgatccccctggagagctgcttcaacatcaacaagcgggcggactccaagaac aagcacctggtggccctctacacccgggacgagcactttgccattgcggcagacagcgag gccgagcaggacagctggtaccaggccctcctgcagctgcacaaccgtgccaagggccac cacgacggggccgcggcgcctggggcgggaggtggcgggggcagctgcagtggcagctcc ggcctcggggaggccggtgaggacttgagctatggggacgtgcccccaggacccgccttc aaggaggtctggcaggtgatcctgaaacccaagggcctgggtcagacaaagaacctgatt ggcatctaccgcctctgcctgaccagcaagaccatcagcttcgtgaagctgaactcggag gcggcggccgtggtgttgcagctgatgaacatcaggcgctgcggccactcagagaacttc ttcttcatcgaagtgggccgttccgcagtgacgggcccgggggagttctggatgcaggtg gacgactccgtggtggcccagaacatgcacgagacaatcctggaggccatgcgggccatg agcgatgagttccgccctagaagcaagagccagtcctcctccaactgctccaaccccatc agtgtgcccctgcggaggcaccacctcaacaaccctccacccagccaggtggggctgacc cgccgctcgcgcaccgagagcatcacagccacctccccggccagcttggtgggcgggaag cagggctccttccgcgtgcgtgcctccagtgatggcgaaggcaccatgtctcgccccgcc tcagtggacggcagtcctgtgagtcctagcaccaacaggacccacgcccaccgccatcga ggcagctcccggctgcacccgcctctcaaccacagccgctccatccccatgccttcttct cgctgctcgccttccgccaccagccctgtcagtctgtcgtccagcagcacgagtggccat ggctccacctcagactgcctcttcccgcggcggtctagtgcttctgtgtctggttccccc agtgatggcggcttcatctcctccgatgagtatggctccagtccctgcgatttccgaagt tccttccgcagcgtcaccccagattccctgggccacaccccgcccgcccggggtgaggag gagctaagcaactatatctgcatgggaggcaagggggcctccaccctcactgcccccaat ggccactacattctgccccggggtggcaatggtcaccgctacgtgccagccgccggcttg ggcacgagcccagccctgccaggagaagaagcagccggtgcggcagatctggataatcgg ttccgaaaacggactcactctgcgggcacctcacctaccatttcccaccagaaaaccccg tctcagtcctctgtggcttccattgaggaatataccgaaatgatgcccgcttacccacca ggaggtggcagtggaggccgagtacccggctaccggcactccgccttcgtgcccacccac tcctacccagaggagggtctggaaatgcaccccttggagcggcgtgggggccaccaccgc ccagacacctccagccttcacactgatgatggctacatgcccatgtccccaggagtggcc ccagtgcccggcagccggaaaggcagtggggactacatgcccatgagccccaagagcgtg tctgccccgcaacagatcatcaaccccatcagacgccatccccagagagtggaccccaac ggctacatgatgatgtccccaagcggcagctgctctcctgacattggaggtgggcccagc agcggtggcagcagcagtggtgccgccccttctgggagcagctatggcaagctttggaca aacggggtagggggccaccactctcacgccctgccacaccccaaacttccggtggagagc ggtagtggcaaactcttgtcttgtgcaggtgactacatgaacatgtcgcccgtcggggac tccaacaccagcagcccctccgactgctattatggccccgaggacccccagcacaagccc gtcctctcctactactcattgccaaggtcctttaagcatacccagcgtcctggggagctg gaggagccccggcaccaccagcacatccgcctttccacaagttccggtcgactcctctac actgcggccgcagaagattcctcttcgtccaccagcagcgacagcctgggcgggggatac tgtggggctcggccggagcctggcctcccgcatctccatcatcaggtcctgcaggcccat ctgcctcgaaaggtggacacagctgcccagaccaacaaccgcctggctcggcccacgagg ctgtctctgggggatcccaaggccagcaccttacctcgggcccgagagcagcagccgccg ccccccttgctgctccctccggagcccaagagcccaggggagtatgtgaatattgaattt gggagcgatcagccaggctacttatcgggcccggtggcgtcccacagctcgccttccatc aggtgtccgtcccagctccagccagctcccagagaggaggagacgggcgcagaagagtat atgaacatggacctggggccgggccggagggccacctggcaggagggcgtgggggtccag ccgggcagggtgggcccggcgccccctggagctgctagcgtgtgtaggccgactagggca gtgcccagcagccgcggcgactacatgaccatgcagatgggcggtcccaggcagagctac gtggacacctcacctgtcgcgcccatcagctacgccgacatgcggaccggcgtcgttgtg gaggatgccagcttgcccggggccactgcggccactccctcctcatcctcgacggcctct gtttcctccactgcgcctccgggaacaggagagctggcggcccgttcggccctcctgggg ggcccgagcgccttcacgcgggttaacctcagtcccaaccgcaaccagagtgccaaagtg atccgtgccgaccctcaagggtgcaggaggcggcacagctccgagaccttctcctctacg cccagtgccacccgggtgggcaacacgatgcccttcggagccggggctgccgttgggggc agcggtggcggcagtagcagcagcgctgaggatgtcaaacgccacagctctgcttccttc gagaacgtgtggctgaggcctggggagctcgggggagcccccaaggaactggcccaagtg tgcggggccgctgggggtttggagaatggtcttaactacatagacctggatttggtcaag gacttcaaacagcgccttcaagagcgcccacctcaaccgcagcctcctgcactcccggcc cctcatcagcctctgggcagtagtcagagcggccccaccagccgctccagcgaggatcta agcgcctatgccagcatcactttccagaagcagccagaggacctccagtag

DBGET integrated database retrieval system