Bufo bufo (common toad): 120994332
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Entry
120994332 CDS
T07950
Name
(RefSeq) 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase-like
KO
K00070
3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:
1.1.1.145
5.3.3.1
]
Organism
bbuf
Bufo bufo (common toad)
Pathway
bbuf00140
Steroid hormone biosynthesis
bbuf01100
Metabolic pathways
Module
bbuf_M00107
Steroid hormone biosynthesis, cholesterol => pregnenolone => progesterone
bbuf_M00110
C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone
bbuf_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
bbuf_M00977
C19-Steroid hormone biosynthesis (androgen backdoor pathway), pregnenolone => androsterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
bbuf00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
120994332
Enzymes [BR:
bbuf01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
120994332
5. Isomerases
5.3 Intramolecular oxidoreductases
5.3.3 Transposing C=C bonds
5.3.3.1 steroid Delta-isomerase
120994332
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Motif
Pfam:
3Beta_HSD
Epimerase
NAD_binding_4
GDP_Man_Dehyd
Polysacc_synt_2
NAD_binding_10
RmlD_sub_bind
NmrA
KR
adh_short
Semialdhyde_dh
Motif
Other DBs
NCBI-GeneID:
120994332
NCBI-ProteinID:
XP_040278737
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Position
3:5880022..5904551
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AA seq
377 aa
AA seq
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MSGTLSGLSCLVTGASGFVGLRIVQMLLEEEERLGEVRAMDKTLSGQLLHTCHRFQSKIQ
VKLLEGDIRDAEFLDRCCQGVDLVIHTAAVIDTTGHVNKETLMSINLHGTELLLESCLQN
NVRYLLYTSSMEVVGPNTRGDPVVNGDEEMVYEGKLGFYYGESKRRAEQAVLRANGRELH
NGWSLVTCSLRPTYIFGEGSQFLQMHLDQVFQNGGVFKRISKKEALVNPVYVGNVAWAHI
LAARAMKDPDGVKKIAGKFYYICDDTPHMSYSDLNHELGKELGLRVEDRLLMPYPLLYFM
ASMMELVSFLLRPFFRFVPPLTRHLAILLNTTFTFSYKKIQSDMGYKPFYKWEEARRLTS
TWMDTILLQRKEARKKK
NT seq
1134 nt
NT seq
+upstream
nt +downstream
nt
atgagcggcacattgtcggggctctcctgcctcgtgaccggggccagcggctttgtggga
ctccgcatcgtgcagatgttactggaggaagaggagcgtctgggagaagtcagagccatg
gacaagaccctgagcggccagctcctgcacacctgccaccggttccagagtaaaatccag
gtgaagcttctagaaggagacatccgcgatgcagaattcctggacagatgctgccaggga
gtggacctggtcatacacaccgcagccgtcatagacaccaccggccacgtcaacaaggag
accctgatgtccatcaacctccacggcacggagctgctcctggagtcttgtctccagaac
aatgtgcggtacctcctctacaccagcagtatggaggtggtggggcccaatactcgtggg
gaccccgtagtgaatggagacgaggagatggtctacgagggtaaattaggcttctactat
ggagagagtaagcgtcgggcggagcaggccgtgctgcgggccaatggtcgggaactccac
aatgggtggtccctggtgacctgctcactgcggcccacctacatctttggagaagggtct
cagtttctccagatgcaccttgaccaggtgtttcagaatgggggagtcttcaaaagaatc
tccaagaaagaagcgttggtcaatccggtctatgtgggaaatgtggcatgggcccatatc
ctggccgctcgggcaatgaaagacccggacggtgtcaagaagattgcagggaaattctac
tacatctgtgatgacaccccccacatgagctactcggacctgaaccatgaactgggcaag
gagctgggcctgcgggtggaggacaggctgctcatgccctatccgttgctctactttatg
gcctccatgatggagttggtcagtttcctactccgtcctttcttcagatttgtgccgcct
ctcaccagacacctggcgatccttctgaacaccaccttcaccttctcctacaagaaaatc
cagagtgatatgggatacaagcccttctacaagtgggaggaggccaggaggctgacctcc
acctggatggacaccatactgctccaacgcaaggaggcacgcaaaaagaaatag
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