KEGG   Bacillus caldolyticus: CWI35_06570
Entry
CWI35_06570       CDS       T08314                                 
Symbol
metH
Name
(GenBank) methionine synthase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
bcal  Bacillus caldolyticus
Pathway
bcal00270  Cysteine and methionine metabolism
bcal00450  Selenocompound metabolism
bcal00670  One carbon pool by folate
bcal01100  Metabolic pathways
bcal01110  Biosynthesis of secondary metabolites
bcal01230  Biosynthesis of amino acids
bcal04980  Cobalamin transport and metabolism
bcal04981  Folate transport and metabolism
Module
bcal_M00017  Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:bcal00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    CWI35_06570 (metH)
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    CWI35_06570 (metH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    CWI35_06570 (metH)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    CWI35_06570 (metH)
   04980 Cobalamin transport and metabolism
    CWI35_06570 (metH)
Enzymes [BR:bcal01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     CWI35_06570 (metH)
SSDB
Motif
Pfam: S-methyl_trans Met_synt_B12 Pterin_bind B12-binding B12-binding_2 CdhD Clathrin_H_link
Other DBs
NCBI-ProteinID: AUI36244
LinkDB
Position
1250162..1253572
AA seq 1136 aa
MANVTLEQQLQRKILVIDGAMGTMIQNANLSAADFGGEAYEGCNEYLTLTAPHVIRRIHE
AYLEAGADIIETNTFGATRIVLDEYNLGHLALELNIEAAKLAKQAAEAFSTPDWPRFVAG
SMGPTTKTLSVTGGATFEELVAAYEEQARGLLLGGVDLLLLETCQDTLNVKAGFLGISKA
FEAVGRRVPLMISGTIEPMGTTLAGQAIDAFFISVRHMKPIAVGLNCATGPEFMTDHLRT
LASLADTAVSCYPNAGLPDEEGRYHETPEMLAEKIRRFAEKGWINIVGGCCGTTPDHIRA
IAEAVRGIPPRAIPSSFDVHAVSGIEALIYEETMRPLFVGERTNVIGSRKFKRLIAEGKY
EEAAEIARAQVKNGAHVIDICLADPDRDELHDMEQFVREVVKKVKVPLVIDSTDERVIER
ALTYSQGKAIINSINLEDGEERFAKVVPLLHKYGAAVVVGTIDEQGMAVTAERKLEIALR
SYDLLVNRYGVPARDIIFDPLVFPVGTGDEQYIGAANETIKGIRLIKEQLPECLTMLGIS
NVSFGLPPAGREVLNSVFLYHCTQAGLDYAIVNTEKLERFASIPEEEVRMAEALLFDTSD
ETLNTFIEFYRSKITAAKPAEENLSLEERLARYVIEGSKDGLIPDLEKALETYSDPLSII
NGPLMAGMDEVGRLFNNNQLIVAEVLQSAEVMKAAVAFLEPYMEKKEGSTKGKVILATVK
GDVHDIGKNLVDIILSNNGYEVIDLGIKVAPQQLIEAVREHQPDIIGLSGLLVKSAQQMV
VTAQDLRQAGISTPILVGGAALTRKFTENKIAPEYDGIVLYAKDAMDGLALANQLQQGEI
DYKKKEATENEPTRPTAVATAFKSNVSTDVPVYIPADLERHVLRNVPLDHVLPYVNWQMV
LGHHLGLKGKVKRLLEEKDEKALALKAVVDELLAEAKERGWIQPAGVYRFFPAQSDGNRV
YIYDPTDGKTVLEMFNFPRQPRAPHLCLADYLKSKESGEMDYVGLFAVTAGHGVRELAQQ
WKDEGEFLKSHAIQALALEIAEGFAERIHQIMRDRWGFPDDPDFTMEERFAAKYQGQRYS
FGYPACPNLEDQEKLFRLLHPEDIGIRLTDGYMMEPEASVSAIVFAHPEARYFNVL
NT seq 3411 nt   +upstreamnt  +downstreamnt
atggctaacgtcaccttagaacagcaactgcaaagaaaaattcttgtcatcgatggcgcc
atgggcacgatgatccaaaacgccaacctatcggccgccgactttggcggcgaggcgtat
gaagggtgcaacgaatatttgaccctcaccgccccgcatgttatccgccgcattcacgaa
gcgtacctagaagccggtgctgatatcattgaaacgaacacgttcggggcgacgcgcatt
gtgctcgatgaatacaacctcgggcatttggcgctcgagttgaacatcgaagcggccaag
ctcgccaaacaagcggcggaggcgttctcaactcccgactggccgcgctttgtcgccggg
tcgatggggccgacgacgaagacgttgtcggtgacaggcggcgcgacctttgaggaactc
gtcgccgcctatgaagaacaagcgcgcgggctgctgttgggcggcgtcgatcttctgttg
ctggagacgtgccaagatacgttgaacgtaaaagccggatttctcggcatttccaaggcg
tttgaggcggtcggccgccgcgtgccgctcatgatttccggcacgatcgagccgatgggc
acgacgctcgccggccaggcgatcgatgcgtttttcatctcggtgcgccatatgaagccg
atcgccgtcggcttaaactgcgcgaccggcccggagtttatgaccgaccatttgcggacg
ctcgcctcgcttgcggatacggcggtcagctgctatccgaacgccgggctgccggatgaa
gaaggccgctaccatgaaacgccggagatgttggcagagaaaatccgccgctttgccgaa
aagggatggatcaacatcgtcggcgggtgttgcggcacgacgccggaccatattcgcgcc
atcgccgaagcggtgcgcggcatcccgccgcgggcgatcccgtcttcgtttgacgtccac
gccgtctccggcatcgaggcgctcatttatgaggaaacgatgcgcccgctctttgtcggc
gagcggacaaacgtcatcggctcgcgcaaattcaagcgcctcatcgccgaagggaaatac
gaagaagcggcggaaatcgcccgcgcccaagtgaaaaacggcgcccatgtcatcgacatt
tgcctcgccgacccagaccgcgacgaactccatgacatggagcagttcgtccgcgaagtc
gtgaaaaaagtgaaagtgccgcttgtcatcgattcaaccgacgagcgcgtcattgaacgc
gccctcacctactcgcaaggaaaagcgatcatcaattcgatcaacttggaagacggcgag
gagcggtttgcgaaagtcgttcctctcttgcacaaatacggcgccgctgtcgtcgtcggc
acgatcgatgaacaagggatggcggtcaccgccgaacgaaagctggaaattgccttgcgt
tcgtatgacttgctcgtgaaccgctacggcgtgccggcgcgcgacatcattttcgatccg
ctcgtcttcccggtcggcaccggtgatgagcaatacatcggcgcggcgaacgaaacgatc
aaaggcattcgcctcattaaagagcaactgccggagtgcttgacgatgctcggcatcagc
aacgtctcgttcggcttgccgccggccgggcgcgaggtgctcaactccgtctttttgtac
cattgcacgcaagctgggctcgattatgcgatcgtcaacactgagaagcttgagcggttc
gcctcgattccggaagaggaagtgcggatggccgaagcgcttttgtttgacacgagcgat
gaaacattaaacacctttatcgaattttaccgaagcaaaatcaccgccgccaagccggct
gaggagaacttgagcttggaagagcggctcgcccgctacgtcattgaagggtcgaaagac
gggctcattcccgatttagagaaggcgcttgagacctactccgatccgctgtcgatcatc
aacggtccgcttatggccggcatggatgaagtcgggcggctgttcaacaacaaccagctc
atcgtcgccgaagtattgcaaagcgcggaagtgatgaaagcggccgtcgcctttttagag
ccgtatatggaaaagaaagaaggaagcacaaaaggaaaagtcattctcgccaccgtcaaa
ggcgatgtccatgacatcggcaaaaacttggtcgacatcattttaagcaacaacggctac
gaggtgatcgacctcggcattaaagtcgctccgcagcaactcattgaagcggtgcgcgaa
catcagcccgacatcatcgggttgtcgggcttgcttgtcaaatcggcccaacagatggtc
gtcaccgcccaagatttgcggcaagccggcatctcaacgcccattttagtcggcggcgcc
gccttgacgcgcaaatttaccgaaaacaaaatcgcacccgaatacgacggcatcgtcttg
tacgcgaaagacgccatggacgggctcgcgctcgccaaccaactccagcaaggcgaaatt
gactacaagaaaaaagaagcgaccgaaaacgagccgacgcggccaacggcggtcgccacc
gcgttcaaatcgaacgtctcgaccgacgttcccgtctacatcccggccgacctcgagcgc
cacgtgctgcgaaacgtgccgcttgaccatgtgttgccgtacgtcaactggcaaatggtg
ctcggccaccacctcggcttgaaaggaaaagtgaaacggctgcttgaagagaaagacgaa
aaagcgttggcgttaaaagcggtcgtcgacgaactgctcgccgaagcgaaagaacgcggc
tggattcaacccgccggcgtctaccgcttcttccctgcacaaagcgacggcaaccgggtt
tacatttacgatccgactgacggcaaaacagtgctcgagatgttcaactttccgcgccaa
ccgcgggcgccgcatctttgcctcgccgattatttgaaatcgaaagaaagcggcgaaatg
gattacgtcggcttgttcgccgtcaccgccgggcatggcgtccgcgaactcgcccaacag
tggaaagacgaaggcgaatttttgaaaagccatgccatccaagcgttggcgctcgagatt
gccgaaggattcgccgaacgaatccaccaaattatgcgcgaccgttggggcttcccggac
gacccggatttcacgatggaagagcgcttcgccgccaaataccaaggccagcgctactcg
ttcggctacccggcctgtccgaacttggaagatcaagaaaagctgttccgcctgcttcat
ccagaagacatcggcatccgtctcaccgacggctatatgatggaacccgaggcatcggtt
tccgcgatcgtcttcgcccatccggaagcgcggtatttcaatgtgttataa

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