Bacillus caldolyticus: CWI35_06570
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Entry
CWI35_06570 CDS
T08314
Symbol
metH
Name
(GenBank) methionine synthase
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
bcal
Bacillus caldolyticus
Pathway
bcal00270
Cysteine and methionine metabolism
bcal00450
Selenocompound metabolism
bcal00670
One carbon pool by folate
bcal01100
Metabolic pathways
bcal01110
Biosynthesis of secondary metabolites
bcal01230
Biosynthesis of amino acids
bcal04980
Cobalamin transport and metabolism
bcal04981
Folate transport and metabolism
Module
bcal_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:
bcal00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
CWI35_06570 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
CWI35_06570 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
CWI35_06570 (metH)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
CWI35_06570 (metH)
04980 Cobalamin transport and metabolism
CWI35_06570 (metH)
Enzymes [BR:
bcal01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
CWI35_06570 (metH)
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Gene cluster
GFIT
Motif
Pfam:
S-methyl_trans
Met_synt_B12
Pterin_bind
B12-binding
B12-binding_2
CdhD
Clathrin_H_link
Motif
Other DBs
NCBI-ProteinID:
AUI36244
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All DBs
Position
1250162..1253572
Genome browser
AA seq
1136 aa
AA seq
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MANVTLEQQLQRKILVIDGAMGTMIQNANLSAADFGGEAYEGCNEYLTLTAPHVIRRIHE
AYLEAGADIIETNTFGATRIVLDEYNLGHLALELNIEAAKLAKQAAEAFSTPDWPRFVAG
SMGPTTKTLSVTGGATFEELVAAYEEQARGLLLGGVDLLLLETCQDTLNVKAGFLGISKA
FEAVGRRVPLMISGTIEPMGTTLAGQAIDAFFISVRHMKPIAVGLNCATGPEFMTDHLRT
LASLADTAVSCYPNAGLPDEEGRYHETPEMLAEKIRRFAEKGWINIVGGCCGTTPDHIRA
IAEAVRGIPPRAIPSSFDVHAVSGIEALIYEETMRPLFVGERTNVIGSRKFKRLIAEGKY
EEAAEIARAQVKNGAHVIDICLADPDRDELHDMEQFVREVVKKVKVPLVIDSTDERVIER
ALTYSQGKAIINSINLEDGEERFAKVVPLLHKYGAAVVVGTIDEQGMAVTAERKLEIALR
SYDLLVNRYGVPARDIIFDPLVFPVGTGDEQYIGAANETIKGIRLIKEQLPECLTMLGIS
NVSFGLPPAGREVLNSVFLYHCTQAGLDYAIVNTEKLERFASIPEEEVRMAEALLFDTSD
ETLNTFIEFYRSKITAAKPAEENLSLEERLARYVIEGSKDGLIPDLEKALETYSDPLSII
NGPLMAGMDEVGRLFNNNQLIVAEVLQSAEVMKAAVAFLEPYMEKKEGSTKGKVILATVK
GDVHDIGKNLVDIILSNNGYEVIDLGIKVAPQQLIEAVREHQPDIIGLSGLLVKSAQQMV
VTAQDLRQAGISTPILVGGAALTRKFTENKIAPEYDGIVLYAKDAMDGLALANQLQQGEI
DYKKKEATENEPTRPTAVATAFKSNVSTDVPVYIPADLERHVLRNVPLDHVLPYVNWQMV
LGHHLGLKGKVKRLLEEKDEKALALKAVVDELLAEAKERGWIQPAGVYRFFPAQSDGNRV
YIYDPTDGKTVLEMFNFPRQPRAPHLCLADYLKSKESGEMDYVGLFAVTAGHGVRELAQQ
WKDEGEFLKSHAIQALALEIAEGFAERIHQIMRDRWGFPDDPDFTMEERFAAKYQGQRYS
FGYPACPNLEDQEKLFRLLHPEDIGIRLTDGYMMEPEASVSAIVFAHPEARYFNVL
NT seq
3411 nt
NT seq
+upstream
nt +downstream
nt
atggctaacgtcaccttagaacagcaactgcaaagaaaaattcttgtcatcgatggcgcc
atgggcacgatgatccaaaacgccaacctatcggccgccgactttggcggcgaggcgtat
gaagggtgcaacgaatatttgaccctcaccgccccgcatgttatccgccgcattcacgaa
gcgtacctagaagccggtgctgatatcattgaaacgaacacgttcggggcgacgcgcatt
gtgctcgatgaatacaacctcgggcatttggcgctcgagttgaacatcgaagcggccaag
ctcgccaaacaagcggcggaggcgttctcaactcccgactggccgcgctttgtcgccggg
tcgatggggccgacgacgaagacgttgtcggtgacaggcggcgcgacctttgaggaactc
gtcgccgcctatgaagaacaagcgcgcgggctgctgttgggcggcgtcgatcttctgttg
ctggagacgtgccaagatacgttgaacgtaaaagccggatttctcggcatttccaaggcg
tttgaggcggtcggccgccgcgtgccgctcatgatttccggcacgatcgagccgatgggc
acgacgctcgccggccaggcgatcgatgcgtttttcatctcggtgcgccatatgaagccg
atcgccgtcggcttaaactgcgcgaccggcccggagtttatgaccgaccatttgcggacg
ctcgcctcgcttgcggatacggcggtcagctgctatccgaacgccgggctgccggatgaa
gaaggccgctaccatgaaacgccggagatgttggcagagaaaatccgccgctttgccgaa
aagggatggatcaacatcgtcggcgggtgttgcggcacgacgccggaccatattcgcgcc
atcgccgaagcggtgcgcggcatcccgccgcgggcgatcccgtcttcgtttgacgtccac
gccgtctccggcatcgaggcgctcatttatgaggaaacgatgcgcccgctctttgtcggc
gagcggacaaacgtcatcggctcgcgcaaattcaagcgcctcatcgccgaagggaaatac
gaagaagcggcggaaatcgcccgcgcccaagtgaaaaacggcgcccatgtcatcgacatt
tgcctcgccgacccagaccgcgacgaactccatgacatggagcagttcgtccgcgaagtc
gtgaaaaaagtgaaagtgccgcttgtcatcgattcaaccgacgagcgcgtcattgaacgc
gccctcacctactcgcaaggaaaagcgatcatcaattcgatcaacttggaagacggcgag
gagcggtttgcgaaagtcgttcctctcttgcacaaatacggcgccgctgtcgtcgtcggc
acgatcgatgaacaagggatggcggtcaccgccgaacgaaagctggaaattgccttgcgt
tcgtatgacttgctcgtgaaccgctacggcgtgccggcgcgcgacatcattttcgatccg
ctcgtcttcccggtcggcaccggtgatgagcaatacatcggcgcggcgaacgaaacgatc
aaaggcattcgcctcattaaagagcaactgccggagtgcttgacgatgctcggcatcagc
aacgtctcgttcggcttgccgccggccgggcgcgaggtgctcaactccgtctttttgtac
cattgcacgcaagctgggctcgattatgcgatcgtcaacactgagaagcttgagcggttc
gcctcgattccggaagaggaagtgcggatggccgaagcgcttttgtttgacacgagcgat
gaaacattaaacacctttatcgaattttaccgaagcaaaatcaccgccgccaagccggct
gaggagaacttgagcttggaagagcggctcgcccgctacgtcattgaagggtcgaaagac
gggctcattcccgatttagagaaggcgcttgagacctactccgatccgctgtcgatcatc
aacggtccgcttatggccggcatggatgaagtcgggcggctgttcaacaacaaccagctc
atcgtcgccgaagtattgcaaagcgcggaagtgatgaaagcggccgtcgcctttttagag
ccgtatatggaaaagaaagaaggaagcacaaaaggaaaagtcattctcgccaccgtcaaa
ggcgatgtccatgacatcggcaaaaacttggtcgacatcattttaagcaacaacggctac
gaggtgatcgacctcggcattaaagtcgctccgcagcaactcattgaagcggtgcgcgaa
catcagcccgacatcatcgggttgtcgggcttgcttgtcaaatcggcccaacagatggtc
gtcaccgcccaagatttgcggcaagccggcatctcaacgcccattttagtcggcggcgcc
gccttgacgcgcaaatttaccgaaaacaaaatcgcacccgaatacgacggcatcgtcttg
tacgcgaaagacgccatggacgggctcgcgctcgccaaccaactccagcaaggcgaaatt
gactacaagaaaaaagaagcgaccgaaaacgagccgacgcggccaacggcggtcgccacc
gcgttcaaatcgaacgtctcgaccgacgttcccgtctacatcccggccgacctcgagcgc
cacgtgctgcgaaacgtgccgcttgaccatgtgttgccgtacgtcaactggcaaatggtg
ctcggccaccacctcggcttgaaaggaaaagtgaaacggctgcttgaagagaaagacgaa
aaagcgttggcgttaaaagcggtcgtcgacgaactgctcgccgaagcgaaagaacgcggc
tggattcaacccgccggcgtctaccgcttcttccctgcacaaagcgacggcaaccgggtt
tacatttacgatccgactgacggcaaaacagtgctcgagatgttcaactttccgcgccaa
ccgcgggcgccgcatctttgcctcgccgattatttgaaatcgaaagaaagcggcgaaatg
gattacgtcggcttgttcgccgtcaccgccgggcatggcgtccgcgaactcgcccaacag
tggaaagacgaaggcgaatttttgaaaagccatgccatccaagcgttggcgctcgagatt
gccgaaggattcgccgaacgaatccaccaaattatgcgcgaccgttggggcttcccggac
gacccggatttcacgatggaagagcgcttcgccgccaaataccaaggccagcgctactcg
ttcggctacccggcctgtccgaacttggaagatcaagaaaagctgttccgcctgcttcat
ccagaagacatcggcatccgtctcaccgacggctatatgatggaacccgaggcatcggtt
tccgcgatcgtcttcgcccatccggaagcgcggtatttcaatgtgttataa
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