KEGG   Bufo gargarizans (Asiatic toad): 122934160
Entry
122934160         CDS       T07965                                 
Symbol
CAD
Name
(RefSeq) CAD protein isoform X1
  KO
K11540  carbamoyl-phosphate synthase / aspartate carbamoyltransferase / dihydroorotase [EC:6.3.5.5 2.1.3.2 3.5.2.3]
Organism
bgar  Bufo gargarizans (Asiatic toad)
Pathway
bgar00220  Arginine biosynthesis
bgar00240  Pyrimidine metabolism
bgar00250  Alanine, aspartate and glutamate metabolism
bgar01100  Metabolic pathways
bgar01240  Biosynthesis of cofactors
Module
bgar_M00051  De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP
Brite
KEGG Orthology (KO) [BR:bgar00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00240 Pyrimidine metabolism
    122934160 (CAD)
  09105 Amino acid metabolism
   00250 Alanine, aspartate and glutamate metabolism
    122934160 (CAD)
   00220 Arginine biosynthesis
    122934160 (CAD)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:bgar01002]
    122934160 (CAD)
Enzymes [BR:bgar01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.3  Carboxy- and carbamoyltransferases
    2.1.3.2  aspartate carbamoyltransferase
     122934160 (CAD)
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.2  In cyclic amides
    3.5.2.3  dihydroorotase
     122934160 (CAD)
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.5  Carbon-nitrogen ligases with glutamine as amido-N-donor
    6.3.5.5  carbamoyl-phosphate synthase (glutamine-hydrolysing)
     122934160 (CAD)
Peptidases and inhibitors [BR:bgar01002]
 Cysteine peptidases
  Family C26: gamma-glutamyl hydrolase family
   122934160 (CAD)
 Metallo peptidases
  Family M38: beta-aspartyl dipeptidase family
   122934160 (CAD)
SSDB
Motif
Pfam: CPSase_L_D2 GATase CPSase_sm_chain OTCace_N OTCace CPSase_L_D3 MGS ATP-grasp Dala_Dala_lig_C Amidohydro_1 ATPgrasp_Ter ATP-grasp_3 Peptidase_C26 GARS_A
Other DBs
NCBI-GeneID: 122934160
NCBI-ProteinID: XP_044145345
LinkDB
Position
4:complement(189232..213451)
AA seq 2263 aa
MAVQAELLLEDGTRFTGRMFGAEVPVSGEVVFQTGMVGYPEALTDPSYKSQILVLTYPLV
GNYGVPQDELDEFGLSKWFESGRIHAAGLIVGECSENPSHWSCAKSLNQWLQEQGIPGLQ
GVDTRALTKKIREKGTMLGKLVPQGTDEKQVPYDDPGKRNLVQEVSLKEPRVFNPGGDVK
IAALDCGLKYNQIRCLCQRGAEVTVLPWDSPIDSAEYDGLFLSNGPGDPVYCQQSVLHIH
RYMEGENPKPLFGICLGHQILSLVIGAKTYKMKYGNRGHNQPCIHAASQRCFITSQNHGY
AVDPHTLPDGWSPLFTNANDHTNEGIIHNSKPFFSVQFHPEHRAGPMDLVCLFDVFLDTV
RDMKAGKTELRTVKERLDHVLTYKDSPNVSDLQSGRPRKVLILGSGGLSIGQAGEFDYSG
SQAIKALKEEKIQTVLINPNIATVQTSKGLADKVYFLPITADYVTQVIKNERPDGVLLTF
GGQTALNCGVELTKRGVLEKYNVRVLGTPVSSIEMTEDRKVFVEKMEEIGEHVAPSEAAF
SLEQAQAAAERLGYPVLVRSAYALGGLGSGFANSKEEMTSLVCQAFAHTTQVLVDKSLKG
WKEIEYEVVRDAYNNCVTVCNMENVDPLGIHTGESIVVAPSQTLNDREYNLLRNTAIKVI
QHLGIVGECNIQYALNPESEQYYIIEVNARLSRSSALASKATGYPLAYVAAKLALGIPLP
VLRNSVTNSTTANFEPSLDYCVVKAPRWDLSKFLRVSTKIGSSMKSVGEVMSVGRSFEEA
FQKALRMVDENCVGFDHTVKSASDEELATPTDKRIFVLAAALRAGYTIERLYELTKIDRW
FLHKMKNITDHVNALEACRDENAMPRSLLHRAKQLGFSDKQIAQAVQSTELAVRKVRQEW
QILPQVKQIDTVAAEWPAQTNYLYLTYNGIEHDLDFQEPHVMVLGSGVYRIGSSVEFDWC
AVGCIQELRKMGFKTIMVNYNPETVSTDYDMCDRLYFDEISFEVVMDIYELENPEGIILS
MGGQLPNNIAMSLHRQQCRVLGTSPEAIDSAENRFKFSRLLDTIGISQPQWKELSDTQCA
LQFCNAVGYPCVVRPSYVLSGAAMNVAYSDDDLEKFLTSAVAVSKEYPVVISKFIQEAKE
IDVDAVACDGVVVAVAISEHVENAGVHSGDATLVTPPQDITPKTLERIKAIVHAVGLELQ
VTGPFNLQLIAKDDQLRVIECNVRVSRSFPFVSKTLGEDLVALATQVIMGEEVEPLGLMA
GTGIVGLKVPQFSFSRLAGADVVLGVEMTSTGEVACFGENRYEAYLKAMLSTGFKIPQNN
ILLTIGSYKNKSELLPTVRTLESLGYSLYASVGTADFYTEHGIKVKAMDWPFEETDNDGA
LKEKQRSIMDHLSENHFDLVINLSMRNSGGRRLSSFVTRGYRTRRLAVDYSVPLIIDIKC
TKLFVEALRQIRVAPPVKTHVDCMTSQKLIRLPGLIDVHVHLREPGATHKEDFSSGTAAA
LAGGVTMVCAMPNTNPAITDAATFSLAQKLAEAGARCDFALFLGACSENAGSLTPIASSA
AGLKMYLNDTYSQLKMDNVSLWMEHFEKWPAHLPIVAHAENQTVAAILMVAQLYKRSVHI
CHVAKKEEILIIKAAKQRGIQVTCEVAPHHLFLCLDDLERLGQKRGQVRPMLGTREDLQA
LWDNLDIIDCFATDHAPHSVEEKEGPNPPPGYPGLETMLPLLLTAVSDGRLTIDDIIKRL
YENPRKIFSLPVQENTYIEVDLEQEWTVPQSMQFTKSKWTPFEGMELKGAIRRVVLRGEV
AYIDGQVLVPAGYGQDVRKWTPPLVAASQPAPPKEMVKTPERHRHVTMQSETIRSRAPSP
RRAGPAGDARFHMPPRIHRSSDPGLQVLRRTSSSLHRGGSARSADEQRERVAKKPPEADL
STIQDGYPHPPPIPRLMSPQNMPIQTVPHVQTSPLLHPFIGQHILSVKQFSKDQMSHLFN
VAHTLRMLVQKERSLDILKGKVMAAMFFEASTRTSSSFAAAMHRLGGSVLSFSETTSSSQ
KGESLADSVQTMSCYADLLVVRHPEPGAVELAAKHCRKPVINAGDGVGEHPTQALLDIFT
IREELGTVNGMTITMVGDLKHGRTVHSLACLLTQYRINLRYVTPRSLRMPSKIVHFVASK
GIKQEEFGSIEEALPDTDVLYMTRIQKERFESKEEYDNCFGQFILTPHIMTRAKKKMVVM
HPMPRVNEISLEVDSDPRAAYFRQAENGMYVRMALLATVLGKY
NT seq 6792 nt   +upstreamnt  +downstreamnt
atggcggtgcaggcagagctgctcctggaggatggaacccgcttcaccgggcgcatgttc
ggggccgaggtcccggtgtccggggaagtggtgttccagactggcatggtgggataccct
gaggccctgacagacccctcctacaagtctcagatcctcgtcctcacctacccgctggtt
ggtaactacggcgtcccgcaggatgagctggatgagtttggacttagtaagtggttcgag
tccggccggatccacgccgccggcttgatcgtgggggaatgttcggagaacccgagtcac
tggagctgcgccaaatcacttaaccaatggcttcaagagcaggggatcccgggactgcaa
ggcgtggacacccgggccctcaccaagaagatccgggagaagggcaccatgctgggcaaa
ctagtaccgcagggcacggatgagaagcaggtgccatatgacgaccccgggaagaggaac
ctggtgcaggaggtgtccctgaaggagcctcgcgtgttcaaccctggaggtgacgtgaag
atcgcagctctggactgtggcctgaagtacaaccagatccgctgcctgtgccagaggggg
gcggaggtgaccgtgctgccctgggactcgccaatcgacagcgcagagtatgacggcctc
ttcctcagtaatggccccggggaccccgtgtactgccagcagtccgtgctccacatccac
cgctacatggagggcgagaacccaaaacccctgtttggaatttgcctggggcaccagatc
ctctccctggtgatcggcgccaagacctacaagatgaaatacggaaatcgcggtcacaac
cagccgtgtatccacgcggcgtcccagcgctgcttcatcacttcccagaaccatggctac
gctgtggacccccacacactcccagacgggtggtctccgctcttcaccaacgccaatgac
cacaccaatgagggaatcattcataactccaagccgtttttcagcgtgcagttccacccg
gagcaccgcgccggccccatggacctcgtctgtctcttcgatgtcttcctggacaccgta
cgtgacatgaaagctgggaagacggagctgcgcacagtgaaggaacgtctcgatcacgtc
ctgacctacaaggactccccgaacgtgagtgacctgcagagcggccgcccccggaaggtg
ctcatcctgggctccggggggctgtccatcggccaggccggagagtttgactactcgggc
tctcaggccattaaagctttgaaggaggagaaaattcagactgtgctcattaaccccaac
attgccacagtgcagacctccaaggggctggccgacaaggtctacttcctgcccatcaca
gcggactacgtgactcaggtgattaagaatgagcggccagacggcgtcctgctaacgttt
ggtggtcagacggctctgaactgcggcgtggagctgaccaagcgcggcgtactggagaag
tacaacgtccgggtgctcgggacccctgtcagctccatagaaatgaccgaggaccggaag
gtgtttgtggagaagatggaggagattggcgagcacgtcgctccaagtgaagccgccttc
tctctagaacaggcacaggcagccgctgaacggctcgggtatccagttctggtgcgctcg
gcctacgcattgggcgggttgggatccggatttgccaactcgaaggaggagatgacgtcg
ttggtgtgccaggcgtttgcccacacgacccaggtgctggtggataaatccctgaagggc
tggaaggagatagagtacgaggtggtgcgggacgcctacaacaactgcgtgacggtgtgt
aacatggagaacgtggacccactgggcattcacaccggagagtccatcgtggtggccccc
agccagaccctgaacgaccgcgagtacaacctgctgcggaacaccgccataaaggtgatc
cagcacctggggattgtgggggagtgtaacatccagtatgcgctaaaccccgaatctgag
cagtattacatcatcgaggtgaatgctcgcctctcccgcagctctgccctggcgagtaag
gcgactggttaccccctggcatacgtggcagcaaagctggctctgggcatcccactgcct
gtcctcaggaactctgtcaccaattccacgaccgccaacttcgagcccagcctggactac
tgcgtggtgaaggcgccgcgctgggacctcagcaagttcctgcgggtcagcaccaagatc
ggcagctccatgaagagcgtgggtgaagtgatgtcggtggggcggagctttgaggaggcg
ttccagaaggcgttgcgcatggtggacgagaactgcgtggggttcgatcacacagtgaag
tctgcatctgatgaggaactggccactcccaccgataagcggatctttgtgctggcggcc
gccctgcgcgctggttacaccattgaacggctgtacgagctgaccaagatcgatcgctgg
ttcctgcacaagatgaagaacatcaccgaccacgtgaacgcgctggaggcatgccgggac
gagaatgccatgccgcgcagtctcctgcaccgcgccaaacagctgggcttctccgacaag
cagatcgcacaggccgtgcagagcacggagctggccgtccggaaggtgaggcaggaatgg
cagattctgccgcaggtgaagcagatcgacacggtggctgcagagtggccagcgcagacc
aattacctgtacctgacctacaacggcatcgagcatgacttggacttccaggagccccac
gtcatggtgctaggatccggcgtctaccgcatcggcagcagcgtggagtttgactggtgt
gcggtgggttgcatccaggaactgcgcaagatgggctttaagactatcatggtgaactac
aacccggagactgtgagcaccgactacgacatgtgcgaccgcctgtatttcgatgagatt
tcctttgaggtggtgatggacatctatgagctggagaacccggaggggattatcctgtcc
atgggggggcagctccctaataacatcgccatgtccctgcaccgtcagcagtgccgtgtc
ctgggcacttcccccgaggccatcgactctgctgagaaccgcttcaagttctctcgcctg
ctggacacgatcgggatcagtcagccgcagtggaaggagctctcagacacacagtgtgcg
cttcagttctgtaacgcggttggttacccctgcgttgtgcggccatcgtacgttttgagc
ggcgctgccatgaatgtggcctattctgatgatgatctggagaagttcctcaccagtgct
gtggccgtgtctaaggagtatccggtggtcatctccaagttcatccaggaagccaaggag
atcgacgttgacgcggtggcatgtgacggggtggtggtcgctgtggccatttctgagcac
gtggagaatgcgggggtgcactctggagatgccacgctggtcacccctcctcaggatatc
acccccaaaactctggagaggattaaggccatcgtccacgcggtggggctggagctccag
gtgacggggccctttaacctccagctgatcgcaaaggacgatcagctgagggtgattgag
tgtaatgtccgagtctcccgctcctttccctttgtctccaagacgcttggggaggatctg
gtggccctggccacgcaagtcattatgggggaagaggtggagccactcgggcttatggca
ggcacaggaattgttggattaaaggtgccgcagttctccttctctcgtctggctggagca
gacgtggttctcggggtggagatgaccagcaccggggaggtggcttgctttggggagaac
cgctatgaggcgtatctgaaggccatgctgagcaccggcttcaagatccctcagaacaac
atcctactgaccatcgggagctacaagaataagagtgagcttctgcccacggtgcggaca
ttggagagcctgggatacagtctgtatgccagcgtgggtacagcggacttctacacagag
catggcatcaaggtgaaagccatggattggccctttgaggaaacggacaacgatggggcc
ctgaaggagaagcagcggagcatcatggaccatctgtctgagaaccactttgaccttgtc
atcaacctctccatgaggaactctggggggcgcagactgtcctcctttgtgacgcgtggt
taccgtacccgccggttggccgtggactactcggtgccccttatcattgatatcaagtgc
accaaactgtttgtggaggctctcaggcagatcagagtggcgcctccagtgaagacccat
gtggactgtatgacttcccagaaactcatccgcctaccaggtctgattgacgtccacgtg
catctgcgggagccaggcgccacacacaaggaagacttctcgtctggaacggcggcagcg
ctggctggtggtgtgaccatggtgtgcgccatgcccaataccaaccctgccatcacagac
gcagccacattctcattggcgcagaagttggcggaggctggcgcccgctgtgactttgcc
ctgttccttggagcgtgttcagagaacgcgggttccctcacccccatcgccagctcagcg
gctggactgaagatgtacctgaacgacacctactcccagctgaagatggacaacgtgtcc
ctgtggatggagcactttgagaagtggcccgctcacttgcccatcgtggctcacgctgag
aaccagacggttgccgccatcttgatggtggcgcagttgtacaagcgatcggtgcacatc
tgccatgtggccaagaaggaggagattctcatcatcaaggcggccaagcagcgggggata
caggtgacttgtgaggtggccccccatcatctcttcctgtgtctggatgacctggagcgg
ctgggtcagaagcgaggccaggtgcgccccatgctgggcaccagagaagacctgcaggca
ctgtgggacaacctggacattattgactgcttcgccacagatcacgcccctcattctgtg
gaggaaaaggaaggtcctaatcctcctcctggatacccgggcctggagaccatgctgccc
cttctgcttactgcagtcagtgatgggcgactgactatcgatgacatcatcaaacggctg
tacgagaacccccgaaaaatcttttccctcccagtccaagagaacacatacatagaggtg
gatctggagcaggagtggaccgtcccgcagtccatgcagttcaccaagtctaagtggact
ccgtttgaagggatggagctgaagggtgcgatacgcagggtggttctccgaggggaagtc
gcctacatagacggccaggttctagtgccggccggttatggtcaggatgtcaggaaatgg
actccaccgctggtcgcagcctcgcagccggcgccccctaaagagatggtgaagactcca
gagcgtcaccgtcatgtcaccatgcagagcgagaccatccgcagccgcgctcccagcccc
cgcagagccggccccgccggagacgcccgcttccatatgccccccagaatccatcgctcc
tctgatcccgggttacaagtgctcaggaggacatcctcatctctgcatcggggcggcagc
gccaggagcgctgatgagcagagggagcgagtggccaagaagcctccagaagcagatctc
tccaccatccaggacggttacccccacccgcccccgatccctcgcctcatgtccccccag
aacatgcccatacagactgtcccccacgtgcagacctccccgctgctgcaccccttcata
ggacagcacatcctgtccgtcaagcagttcagcaaggatcagatgtcgcacctctttaat
gtggcgcacacgctgcggatgctggtgcagaaggagcgcagtttggacattctcaagggt
aaagtaatggccgccatgtttttcgaggcgagcacacggaccagcagctcctttgcggca
gccatgcatcgcctgggcggctctgtgctctcgttttcggagactacgtcgtcctctcag
aagggggagtcgctggcggactctgttcagaccatgagctgttacgcggatctgctggtg
gtgagacatccagagccaggcgctgtggagcttgccgctaagcactgccgtaaaccagtg
atcaatgcgggagacggggtgggagagcatccaacacaagccctgctggatatcttcacc
atccgggaggagctgggcaccgtcaacgggatgacgatcaccatggtcggagatctgaag
catggccgcacagtccactctctcgcctgcctcctgacccaataccgcatcaatctgaga
tacgtgacgccgcgcagcctgcgcatgccctccaagatcgtccactttgtggcttccaag
ggaatcaagcaggaggagttcggcagcattgaggaggcgctcccggacacagacgtgctc
tacatgacccggatacagaaggagaggtttgagagcaaggaggagtatgacaattgtttt
ggacagttcatcctcaccccacacatcatgacccgtgccaagaagaagatggtggtgatg
cacccgatgccacgtgtcaatgagatcagtcttgaagtggactcggaccctcgggcagcg
tacttccgccaggccgagaacgggatgtacgtgcggatggcgctgctggccacagtcctg
ggaaagtactga

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