KEGG   Brevibacillus humidisoli: LOK74_00245
Entry
LOK74_00245       CDS       T08900                                 
Symbol
ligA
Name
(GenBank) NAD-dependent DNA ligase LigA
  KO
K01972  DNA ligase (NAD+) [EC:6.5.1.2]
Organism
bhui  Brevibacillus humidisoli
Pathway
bhui03030  DNA replication
bhui03410  Base excision repair
bhui03420  Nucleotide excision repair
bhui03430  Mismatch repair
Brite
KEGG Orthology (KO) [BR:bhui00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03030 DNA replication
    LOK74_00245 (ligA)
   03410 Base excision repair
    LOK74_00245 (ligA)
   03420 Nucleotide excision repair
    LOK74_00245 (ligA)
   03430 Mismatch repair
    LOK74_00245 (ligA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:bhui03032]
    LOK74_00245 (ligA)
   03400 DNA repair and recombination proteins [BR:bhui03400]
    LOK74_00245 (ligA)
Enzymes [BR:bhui01000]
 6. Ligases
  6.5  Forming phosphoric-ester bonds
   6.5.1  Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)
    6.5.1.2  DNA ligase (NAD+)
     LOK74_00245 (ligA)
DNA replication proteins [BR:bhui03032]
 Prokaryotic type
  DNA Replication Elongation Factors
   Elongation factors (bacterial)
    Other elongation factors
     LOK74_00245 (ligA)
DNA repair and recombination proteins [BR:bhui03400]
 Prokaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    DNA ligase
     LOK74_00245 (ligA)
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     LOK74_00245 (ligA)
   MMR (mismatch excision repair)
    DNA ligase
     LOK74_00245 (ligA)
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    SHDIR (short-homology-dependent illegitimate recombination)
     RecET pathway
      LOK74_00245 (ligA)
SSDB
Motif
Pfam: DNA_ligase_aden DNA_ligase_OB HHH_2 BRCT DNA_ligase_ZBD HHH_5 Nlig-Ia PTCB-BRCT HHH
Other DBs
NCBI-ProteinID: UFJ41032
LinkDB
Position
50780..52789
AA seq 669 aa
MDRLTAERKIEELRQQIERHNRLYHVEDRPEITDQEYDQLMRELRDLEDLYPDLVTSDSP
TQRVGGEPLPHFEKVEHKVPMLSLGNAFDEADLRDFDRRVRQGVGEQPVRYVCELKIDGL
AVSLRYENGLFVQGATRGDGQTGEDITQNLKTIRSIPLRLSKPVTIEVRGEAFMPKPAFE
KLNQEREAKGEPLFANPRNSAAGSLRQLDPKIAASRSLDTFIYGIGELQGESVDFHSEGL
ELLQSLGFKVNPEWRVFDAIDELIAFIQSWAEKRPALPYEIDGMVIKVDSFAQRQELGFT
AKSPRWAVAYKFPAEEAVTVLEGIEVSVGRTGAVTPTALLKPVSLAGTTVKRASLHNEEI
IREKGLLLGDHVVVKKAGDIIPEIVAVLPERRTGEERPFQMPTHCPECGSDLVRFEDEVA
LRCINPDCPALIREGMIHFVSRLAMNIEGLGEKVVAQLYEQGLITSVADLYYLHERRDEL
LNMERMGEKSVDNLLEAIEASKQNSVERLIFGLGIRLVGAKAAKVLAEQFGHLDVLRQAT
REQLLEINEIGPKMADSILTYFSMPQVQELLDRLRAAGVNFSYKGVRVEAGNDTPLAGKT
VVLTGTLNTLTRQEAEEKIALLGGKVTGSVSKKTDLVIAGDKAGSKLEKAEKLGIEVIDE
AAFLKLLDQ
NT seq 2010 nt   +upstreamnt  +downstreamnt
atggatcggctgacggctgaacggaaaatagaggaattgcggcaacaaatcgagcgtcac
aaccgtctgtatcatgtagaagatcgaccggagatcactgaccaagaatacgaccaattg
atgcgtgaactaagagacctggaggacctgtaccctgatctggtgacgagtgattcgccg
acgcagcgggtaggtggcgaaccgcttcctcactttgagaaagtggaacacaaagttccc
atgctcagtctgggcaacgcctttgacgaggctgacttgcgcgactttgaccgccgtgtt
cggcagggagtaggtgaacagccagttcgctatgtgtgcgagttgaagattgacgggctg
gcagtctcccttcgctacgagaacggcttgttcgtacaaggggcgacccgtggggacggg
cagacgggcgaggatattacgcagaatctaaagacgatccgttccatcccgcttcggttg
agcaagccggtgacgatcgaagtgagaggcgaagcgtttatgcccaagccggctttcgaa
aagctgaatcaggagcgggaagcaaagggtgaacccctgtttgccaatccgcgcaattcc
gctgctggttctctgcgccagctagacccgaagatcgccgcctcccgctcgttggacacg
tttatctacgggattggcgaactgcaaggcgaatcggtggactttcacagtgaagggctt
gaactgctgcagtcgctcggcttcaaggtgaatccggagtggcgcgtttttgatgctatc
gatgagttgattgccttcattcaatcgtgggcggaaaagcggcccgctctaccgtacgag
atcgacggcatggtgatcaaggtagacagctttgcccagcggcaggaactagggttcacc
gcaaaaagtccgcgatgggcggttgcctacaagtttccggcagaagaagctgtgacggtg
ctggaaggcatcgaggtgagcgtcggacggaccggcgcggttacgccgacggcgctgttg
aaaccggtcagcctggcggggaccactgtgaagcgagcctctctgcacaatgaagagatt
atccgggaaaaaggacttttgcttggcgatcacgtcgtggtgaaaaaagcgggcgacatc
attccagagattgtcgctgtcctgccagagcggagaaccggtgaggaacggccgttccag
atgccgacacactgtccggaatgcggcagtgacctggttcgctttgaggatgaagtagcg
ctgcgctgcatcaatcctgactgcccggcgctgatacgggagggtatgattcactttgtc
tcacggctcgcgatgaacatcgaagggcttggtgaaaaggtagttgcccagttgtatgag
caagggctgattaccagtgttgccgatctctattacctgcacgagcggcgcgatgaactg
ctcaacatggagcggatgggggaaaaatcggtcgacaacctgctggaagcaatcgaagcg
agcaaacagaattctgtggagcggctcatcttcggtctcggcatccggttggtcggagcc
aaagcagccaaagtgctggccgagcagtttggtcacctcgatgtgcttcggcaggctacg
cgggagcaactgctggagattaacgagatcggaccgaagatggctgacagcatcctcact
tacttttcaatgccgcaggtacaggagttattggaccggctgcgtgctgccggcgtcaac
ttcagctacaaaggggtccgcgtcgaagcggggaacgacacgccgttggctggcaaaaca
gtagtgttgactggtacgttgaacacactgacccgtcaggaggcagaggagaaaattgct
ctgttgggcggaaaggtgacaggcagtgtcagcaaaaaaacagacctggtgatcgccggt
gacaaagcaggttccaagctggaaaaggcggagaagttgggcatagaggtgatcgacgaa
gcggcctttctgaagctgcttgatcagtag

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