KEGG   Brevibacillus humidisoli: LOK74_11305
Entry
LOK74_11305       CDS       T08900                                 
Symbol
metH
Name
(GenBank) methionine synthase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
bhui  Brevibacillus humidisoli
Pathway
bhui00270  Cysteine and methionine metabolism
bhui00450  Selenocompound metabolism
bhui00670  One carbon pool by folate
bhui01100  Metabolic pathways
bhui01110  Biosynthesis of secondary metabolites
bhui01230  Biosynthesis of amino acids
bhui04980  Cobalamin transport and metabolism
bhui04981  Folate transport and metabolism
Module
bhui_M00017  Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:bhui00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    LOK74_11305 (metH)
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    LOK74_11305 (metH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    LOK74_11305 (metH)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    LOK74_11305 (metH)
   04980 Cobalamin transport and metabolism
    LOK74_11305 (metH)
Enzymes [BR:bhui01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     LOK74_11305 (metH)
SSDB
Motif
Pfam: S-methyl_trans Met_synt_B12 Pterin_bind B12-binding_2 B12-binding CdhD KH_6
Other DBs
NCBI-ProteinID: UFJ43032
LinkDB
Position
complement(2269953..2273417)
AA seq 1154 aa
MVKPTRFTEQLQRKILVLDGAMGTMLQQANLSAADFGGEEYEGCNELLNLTRPDVIRYIH
EKYLEAGADIIETNTFGATNVVLAEYDVQEKDMEINIAAARIAQEAAAAYSTPDWPRFVA
GSMGPTTKTLSLTGGVTFEELVEAYCRQAKGLILGGVDVLLLETAQDTLNVKAAGIGIRQ
AFAELEREVPVMISGTIEPMGTTLAGQNIESFYISIEHLNPVTIGLNCATGPEFMRDHLR
TLSQLAQCGVSCYPNAGLPDEDGHYHESPQGLAAKMAAFAERGWLNVAGGCCGTTPEHIR
ALSEALKGYKPRGQAAPHLSAVSGIDVVYVEEDNRPLLVGERTNVIGSRKFRQLIADGKY
EEASDIARAQVKRGAQIIDICLADPDRDEYADMEQFLQYAVKKVKAPLMLDSTDAKVLEL
GLKHSQGKAIINSINLEDGEERFAQVVPLIHTYGAAVVVGTIDEQGMAVTRERKLEVAKR
SYDLLVNRYGVHPQDIIFDPLVFPVGTGDEQYIGSALETVEGIRLIKQAMPECKTILGVS
NVSFGLPPAGREVLNAVYLYHTTRAGLDYAIVNTEKLERYASIPEDERRLAEALLFETND
QTLASFTEFYRQKKQTVKVETSTLSLEERLARYVVEGSKDGLIPDLEEALKKYAPLEIIN
GPLMAGMEEVGRLFNDNQLIVAEVLQSAEVMKASVAFLEPFMEKTESSSKGKILLATVKG
DVHDIGKNLVEIILGNNGYEVVNLGIKVPPEQLIAACRREQPDLIGLSGLLVKSAQQMVI
TAQDLRTAGVDVPLMVGGAALTRKFTQTRIAPEYSGVVVYAKDAMDGLELANKLQDPQAR
SQLQQAIQEEQEKAAAQASGGAAPGKTTASIKRSPINRTGPVFTPPDHDRHVLRDYPISY
LQPYLNLRMLLGKHLGVRGNVEKLLADGDKKVTEIYAVVEDLLASARESGLIRAHGMYQF
FPAQADGDDILIYDPANTSRVLERFSFPRQPSEPYLCLSDFLRPVESGEMDCVGFLAVTA
GQGIRHQAEGWKNQGEYLRSHILQALALELAEAFAERIHHVMRDVWGFPDSADMTMAERF
GARYQGIRVSFGYPACPNLDDQEKLFRLLKPEDIGIQLTDGFMMDPEASVSAMVFAHPEA
RYFNAVPVAVEANE
NT seq 3465 nt   +upstreamnt  +downstreamnt
atggtgaaaccgacacgatttacggaacaactacagcgaaagatcctggtccttgatgga
gcgatggggaccatgcttcagcaggccaatctcagcgcggccgacttcggtggagaggaa
tacgaggggtgcaatgagttgttaaacctgactcgtcctgacgtgatccggtacatccac
gagaagtatctggaagcgggtgccgatatcatcgagaccaacacatttggcgccaccaat
gtggttctcgcagaatacgacgtgcaggagaaagatatggagatcaatatcgcggctgcc
aggattgcccaggaagcggcagcagcctactcaacgccagactggccgcgcttcgtcgcc
ggttcgatgggaccgacgaccaagaccctctcgctgactggtggtgtcacttttgaagag
ttggtcgaagcgtattgccgacaggcgaagggcttgatccttggaggtgttgacgtcctc
ctgttggagacggcgcaggacaccttaaacgtaaaggcagcaggcatcgggattcggcag
gcatttgccgagttggagcgggaagtgccggtgatgatctccggtacaatcgagccgatg
ggtacgacgctggctggtcagaatattgagtcattctatatctccatcgaacacttaaat
ccggtcacgatcgggttgaactgcgcgacagggcccgagttcatgcgtgatcatttgcgt
acgttgtcacagttggcgcagtgtggcgtcagttgttaccccaatgccggactgcccgat
gaggacggacactatcatgaatcgccgcagggattggccgccaaaatggctgccttcgct
gaacgcggctggttgaatgtcgctggcggctgctgtggaacgactcccgaacatatccgc
gcgctgtcagaggcattaaagggatacaaaccgcgtggtcaggctgccccgcatctcagc
gctgtctccggtatcgatgtggtgtatgtggaggaagacaatcggccgctgttggttgga
gagcgtaccaatgttatcggctcgcgaaagttccgccagctgatagcggacggcaagtac
gaagaagcgtctgatattgcgcgtgcccaagtgaagcgcggggcccagatcatcgacatc
tgtctggccgaccccgaccgggacgaatacgccgatatggagcagttcctgcaatacgcg
gtaaaaaaagtaaaagctccgctgatgctggactcgactgacgccaaggtattggagcta
gggctgaagcattcacaagggaaagcgattatcaactcgatcaacctggaggatggagag
gagcgctttgcccaggtggtcccgctgatccacacatacggtgcggcagtcgtagtgggg
acgatcgacgaacaggggatggcggttacccgggagcgaaaactggaggtcgccaaacgc
tcctacgacctgttggtcaatcgctacggggttcatccacaggatatcatctttgatccg
ctggtctttccggtgggtacaggggatgagcagtacatcggttctgcactggagacagtt
gaggggatccgcttgatcaaacaggcgatgccggagtgcaagacaatcctcggcgtcagc
aacgtgtcatttgggctgccgccggccggtcgggaggtgctgaatgccgtctacctctac
catacgacgcgagctggattggattacgcgattgtcaacacggaaaagctggaacgatac
gcatcgattccagaggacgagcgtaggctggcggaagccctgctgtttgagaccaatgat
cagacattggcctcctttaccgagttttaccgacagaaaaagcagacggtgaaagtggag
acctctacgctgagcctagaagagcggttggcccgctatgtggtagaaggctcaaaagac
gggttgattcctgatttggaagaagcgctcaagaagtatgcgccactagagatcatcaat
ggtccgctgatggccgggatggaagaagtggggcgtttgtttaacgacaatcaactgatt
gttgccgaagtgctgcagagtgcggaagtgatgaaggcgtctgttgcctttctggaaccg
tttatggaaaagacggagagttcgtcaaaaggcaaaatcctcttggccaccgtaaaaggg
gatgtgcacgatatcgggaaaaacctggtggaaatcatcctcggaaacaacggttacgaa
gtcgtcaacctggggatcaaggtaccgccggaacagttgattgccgcctgtcgcagagaa
cagcccgacttgattggtttgtccggactgctggtgaagtcggcccagcagatggtgatc
accgctcaagatctgcgaacggcaggggtcgatgtcccgctgatggtgggtggagcggca
ctgactcgcaagtttacgcagacgcggatcgccccggagtacagtggtgtggtcgtctac
gccaaagatgcgatggacggactggagctggccaacaagctgcaggacccgcaggctcgg
tcccaattgcagcaggcgatccaggaggagcaggaaaaagcggctgcgcaggcaagtgga
ggggcagctccggggaaaacgactgcatcgatcaagcgttctccgatcaaccggaccggt
cctgtattcacgccgccggatcatgaccgacatgtcctgcgcgactatcccatcagctat
ctgcagccgtatctcaacctgcggatgttgctgggcaaacacctgggcgtgcgcggcaac
gtagagaaactgctcgctgatggtgacaaaaaggttactgagatctacgccgtggtggaa
gatctgctcgcttcggcaagagagtcaggattgatccgggctcatggcatgtaccaattc
tttccggcacaggctgacggtgacgatatcctgatttacgaccctgccaatacgtctcgt
gtcctggagcgatttagtttcccgcgccagccgtcggagccttatctctgcctgtccgac
ttcttgcgtccggtagagagcggcgagatggactgcgtcgggtttctggcagtaacggcc
ggacaggggatccgccatcaggcggaagggtggaaaaatcagggggagtatctacgctca
cacatcttgcaggcgctggctctcgagctggccgaggcgtttgccgagcggatccaccat
gtgatgcgggacgtctggggcttccccgattcagcagacatgaccatggcagagcggttc
ggtgcccgctatcaaggcatacgtgtctcatttggctatcccgcctgtcccaacctggac
gatcaagagaagctgttccgcttgctgaagccggaggatatcggcatccagttgacagac
ggatttatgatggatccggaagcgtctgtttcggcgatggtgttcgcccatccggaagct
cgttattttaacgctgtgcctgttgcagtggaagcaaacgagtaa

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