KEGG   Bos indicus (zebu cattle): 109552991
Entry
109552991         CDS       T04792                                 
Symbol
PTEN
Name
(RefSeq) phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
  KO
K01110  phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
Organism
biu  Bos indicus (zebu cattle)
Pathway
biu00562  Inositol phosphate metabolism
biu01100  Metabolic pathways
biu01521  EGFR tyrosine kinase inhibitor resistance
biu04068  FoxO signaling pathway
biu04070  Phosphatidylinositol signaling system
biu04071  Sphingolipid signaling pathway
biu04115  p53 signaling pathway
biu04140  Autophagy - animal
biu04150  mTOR signaling pathway
biu04151  PI3K-Akt signaling pathway
biu04218  Cellular senescence
biu04510  Focal adhesion
biu04931  Insulin resistance
biu05165  Human papillomavirus infection
biu05166  Human T-cell leukemia virus 1 infection
biu05200  Pathways in cancer
biu05206  MicroRNAs in cancer
biu05208  Chemical carcinogenesis - reactive oxygen species
biu05213  Endometrial cancer
biu05214  Glioma
biu05215  Prostate cancer
biu05218  Melanoma
biu05222  Small cell lung cancer
biu05224  Breast cancer
biu05225  Hepatocellular carcinoma
biu05230  Central carbon metabolism in cancer
biu05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
biu05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:biu00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    109552991 (PTEN)
 09130 Environmental Information Processing
  09132 Signal transduction
   04068 FoxO signaling pathway
    109552991 (PTEN)
   04070 Phosphatidylinositol signaling system
    109552991 (PTEN)
   04071 Sphingolipid signaling pathway
    109552991 (PTEN)
   04151 PI3K-Akt signaling pathway
    109552991 (PTEN)
   04150 mTOR signaling pathway
    109552991 (PTEN)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    109552991 (PTEN)
  09143 Cell growth and death
   04115 p53 signaling pathway
    109552991 (PTEN)
   04218 Cellular senescence
    109552991 (PTEN)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    109552991 (PTEN)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    109552991 (PTEN)
   05206 MicroRNAs in cancer
    109552991 (PTEN)
   05208 Chemical carcinogenesis - reactive oxygen species
    109552991 (PTEN)
   05230 Central carbon metabolism in cancer
    109552991 (PTEN)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    109552991 (PTEN)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    109552991 (PTEN)
   05214 Glioma
    109552991 (PTEN)
   05218 Melanoma
    109552991 (PTEN)
   05215 Prostate cancer
    109552991 (PTEN)
   05213 Endometrial cancer
    109552991 (PTEN)
   05224 Breast cancer
    109552991 (PTEN)
   05222 Small cell lung cancer
    109552991 (PTEN)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    109552991 (PTEN)
   05165 Human papillomavirus infection
    109552991 (PTEN)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    109552991 (PTEN)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    109552991 (PTEN)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    109552991 (PTEN)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:biu01009]
    109552991 (PTEN)
Enzymes [BR:biu01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     109552991 (PTEN)
    3.1.3.48  protein-tyrosine-phosphatase
     109552991 (PTEN)
    3.1.3.67  phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase
     109552991 (PTEN)
Protein phosphatases and associated proteins [BR:biu01009]
 Protein tyrosine phosphatases (PTPs)
  Class I PTPs (Dual specificity phosphatases)
   Phosphatase and Tensin homologs (PTEN)
    109552991 (PTEN)
SSDB
Motif
Pfam: PTEN_C2 DUF3256
Other DBs
NCBI-GeneID: 109552991
NCBI-ProteinID: XP_019808328
UniProt: A0A6P5ANB5
LinkDB
Position
26:10044428..10083743
AA seq 270 aa
MICAYLLHRGKFLKAQEALDFYGEVRTRDKKGVTIPSQRRYVYYYSYLLKNHLDYRPVAL
LFHKMMFETIPMFSGGTCNPQFVVCQLKVKIYSSNSGPTRREDKFMYFEFPQPLPVCGDI
KVEFFHKQNKMLKKDKMFHFWVNTFFIPGPEETSEKVENGSLCDQEIDSICSIERADNDK
EYLVLTLTKNDLDKANKDKANRYFSPNFKVKLYFTKTVEESSNPEASSSTSVTPDVSDNE
PDHYRYSDTTDSDPENEPFDEDQHTQITKV
NT seq 813 nt   +upstreamnt  +downstreamnt
atgatttgtgcatatttgttacatcggggcaaatttttaaaggcacaagaggccctagat
ttctatggggaagtaaggaccagagacaaaaagggagtaactattcccagtcagaggcgc
tatgtgtattattatagctacctgttaaagaatcatctggattatagaccagtggcactg
ttgtttcacaagatgatgtttgaaactattccaatgttcagtggtggaacttgcaatcct
cagtttgtggtctgccagctaaaggtgaagatatattcctccaattcaggacccacacga
cgggaagacaagttcatgtactttgagttccctcagccattgcctgtgtgtggtgacatc
aaagtagagttcttccacaaacagaacaagatgctaaaaaaggacaaaatgtttcacttt
tgggtaaacacattcttcataccaggaccagaggaaacctcagaaaaagtagaaaatgga
agtctatgtgatcaagaaattgatagtatttgcagtatagagcgtgcagataatgacaag
gaatatctagtactcactttaacaaaaaatgatctcgacaaagcaaataaagacaaggcc
aaccgatacttttctccaaattttaaggtgaagctgtacttcacaaaaacagtagaggag
tcatcaaatccagaggctagcagttcaacttctgtaacaccagatgttagtgacaatgaa
cctgatcattatagatattctgacaccactgactctgatccagagaatgaaccttttgat
gaagatcagcatacacaaattacaaaagtctga

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