Bos indicus (zebu cattle): 109557525 Help Entry 109557525         CDS       T04792                                  Symbol ADCY1 Name (RefSeq) adenylate cyclase type 1   KO K08041   adenylate cyclase 1 [EC:4.6.1.1] Organism biu  Bos indicus (zebu cattle) Pathway biu00230   Purine metabolism biu01100   Metabolic pathways biu01522   Endocrine resistance biu04015   Rap1 signaling pathway biu04020   Calcium signaling pathway biu04022   cGMP-PKG signaling pathway biu04024   cAMP signaling pathway biu04062   Chemokine signaling pathway biu04072   Phospholipase D signaling pathway biu04081   Hormone signaling biu04082   Neuroactive ligand signaling biu04114   Oocyte meiosis biu04211   Longevity regulating pathway biu04213   Longevity regulating pathway - multiple species biu04261   Adrenergic signaling in cardiomyocytes biu04270   Vascular smooth muscle contraction biu04371   Apelin signaling pathway biu04540   Gap junction biu04611   Platelet activation biu04713   Circadian entrainment biu04714   Thermogenesis biu04720   Long-term potentiation biu04723   Retrograde endocannabinoid signaling biu04724   Glutamatergic synapse biu04725   Cholinergic synapse biu04727   GABAergic synapse biu04750   Inflammatory mediator regulation of TRP channels biu04911   Insulin secretion biu04912   GnRH signaling pathway biu04913   Ovarian steroidogenesis biu04914   Progesterone-mediated oocyte maturation biu04915   Estrogen signaling pathway biu04916   Melanogenesis biu04918   Thyroid hormone synthesis biu04921   Oxytocin signaling pathway biu04923   Regulation of lipolysis in adipocytes biu04925   Aldosterone synthesis and secretion biu04926   Relaxin signaling pathway biu04927   Cortisol synthesis and secretion biu04928   Parathyroid hormone synthesis, secretion and action biu04934   Cushing syndrome biu04935   Growth hormone synthesis, secretion and action biu04970   Salivary secretion biu04971   Gastric acid secretion biu04972   Pancreatic secretion biu04976   Bile secretion biu05032   Morphine addiction biu05142   Chagas disease biu05146   Amoebiasis biu05163   Human cytomegalovirus infection biu05166   Human T-cell leukemia virus 1 infection biu05200   Pathways in cancer biu05207   Chemical carcinogenesis - receptor activation biu05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:biu00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     109557525 (ADCY1)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     109557525 (ADCY1)    04371 Apelin signaling pathway     109557525 (ADCY1)    04020 Calcium signaling pathway     109557525 (ADCY1)    04072 Phospholipase D signaling pathway     109557525 (ADCY1)    04024 cAMP signaling pathway     109557525 (ADCY1)    04022 cGMP-PKG signaling pathway     109557525 (ADCY1)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     109557525 (ADCY1)    04081 Hormone signaling     109557525 (ADCY1)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     109557525 (ADCY1)   09144 Cellular community - eukaryotes    04540 Gap junction     109557525 (ADCY1)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     109557525 (ADCY1)    04062 Chemokine signaling pathway     109557525 (ADCY1)   09152 Endocrine system    04911 Insulin secretion     109557525 (ADCY1)    04923 Regulation of lipolysis in adipocytes     109557525 (ADCY1)    04912 GnRH signaling pathway     109557525 (ADCY1)    04913 Ovarian steroidogenesis     109557525 (ADCY1)    04915 Estrogen signaling pathway     109557525 (ADCY1)    04914 Progesterone-mediated oocyte maturation     109557525 (ADCY1)    04921 Oxytocin signaling pathway     109557525 (ADCY1)    04926 Relaxin signaling pathway     109557525 (ADCY1)    04935 Growth hormone synthesis, secretion and action     109557525 (ADCY1)    04918 Thyroid hormone synthesis     109557525 (ADCY1)    04928 Parathyroid hormone synthesis, secretion and action     109557525 (ADCY1)    04916 Melanogenesis     109557525 (ADCY1)    04925 Aldosterone synthesis and secretion     109557525 (ADCY1)    04927 Cortisol synthesis and secretion     109557525 (ADCY1)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     109557525 (ADCY1)    04270 Vascular smooth muscle contraction     109557525 (ADCY1)   09154 Digestive system    04970 Salivary secretion     109557525 (ADCY1)    04971 Gastric acid secretion     109557525 (ADCY1)    04972 Pancreatic secretion     109557525 (ADCY1)    04976 Bile secretion     109557525 (ADCY1)   09156 Nervous system    04724 Glutamatergic synapse     109557525 (ADCY1)    04727 GABAergic synapse     109557525 (ADCY1)    04725 Cholinergic synapse     109557525 (ADCY1)    04720 Long-term potentiation     109557525 (ADCY1)    04723 Retrograde endocannabinoid signaling     109557525 (ADCY1)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     109557525 (ADCY1)   09149 Aging    04211 Longevity regulating pathway     109557525 (ADCY1)    04213 Longevity regulating pathway - multiple species     109557525 (ADCY1)   09159 Environmental adaptation    04713 Circadian entrainment     109557525 (ADCY1)    04714 Thermogenesis     109557525 (ADCY1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     109557525 (ADCY1)    05207 Chemical carcinogenesis - receptor activation     109557525 (ADCY1)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     109557525 (ADCY1)    05163 Human cytomegalovirus infection     109557525 (ADCY1)   09174 Infectious disease: parasitic    05146 Amoebiasis     109557525 (ADCY1)    05142 Chagas disease     109557525 (ADCY1)   09165 Substance dependence    05032 Morphine addiction     109557525 (ADCY1)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     109557525 (ADCY1)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     109557525 (ADCY1)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     109557525 (ADCY1) Enzymes [BR:biu01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      109557525 (ADCY1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Guanylate_cyc AC_N Adcy_cons_dom Motif Other DBs NCBI-GeneID:  109557525 NCBI-ProteinID:  XP_019814464 UniProt:  A0A6P5BQU8 LinkDB All DBs Position 4:complement(78863091..78969551) Genome browser AA seq 1128 aa AA seqDB search LAVGGGGGGGAGESVGAERRAGPGGRRGLRACDEEFACPELEALFRGYTLRLEQAATLKA LAXLSLLAGALALAELLGAPGPAPGLAKGSHPVHCVLFLALLVVTNVRSLQVPQLQQVGQ LALLFSLTFALLCCPFALGGPAGAHAGAAAVPATADQGVWQLLLVTFVSYALLPVRSLLA IGFGLVVAASHLLVTATLVPAKRPRLWRTLGANALLFLGVNVYGVFVRILAERAQRKAFL QARNCIEDRLRLEDENEKQERLLMSLLPRNVAMEMKEDFLKPPERIFHKIYIQRHDNVSI LFADIVGFTGLASQCTAQELVKLLNELFGKFDELATENHCRRIKILGDCYYCVSGLTQPK TDHAHCCVEMGLDMIDTITSVAEATEVDLNMRVGLHTGRVLCGVLGLRKWQYDVWSNDVT LANVMEAAGLPGKVHITKTTLACLNGDYEVEPGHGHERNSFLKTHNIETFFIVPSHRRKI FPGLILSDIKPAKRMKFKTVCYLLVQLMHCRKMFKAEIPFSNVMTCEDDDKRRALRTASE KLRNRSSFSTNVVQTTPGTRVNRYIGRLLEARQMELEMADLNFFTLKYKQAERERKYHQL QDEYFTSAVVLALILAALFGLVYLLIIPQSVAVLLLLVFCICFLVACVLYLHITRVQCFP GCLTIQIRTVLCIFIVVLIYSVAQGCVVGCLPWSXCSSPNGSLVVLSSGGRDPVLPVPPC ESAPHALLCGLVGTLPLAIFLRVSSLPKMILLAVLTTSYILVLELSGYTKAMGAGAISGR SFEPIVAILLFSCTLALHARQVDVKLRLDYLWAAQAEEERDDMEKVKLDNKRILFNLLPA HVAQHFLMSNPRNMDLYYQSYSQVGVMFASIPNFNDFYIELDGNNMGVECLRLLNEIIAD FDELMDKDFYKDLEKIKTIGSTYMAAVGLAPTAGTKAKKCISSHLSTLADFAIEMFDVLD EINYQSYNDFVLRVGINVGPVVAGVIGARRPQYDIWGNTVNVASRMDSTGVQGRIQVTEE VHRLLRRGSYRFVCRGKVSVKGKGEMLTYFLEGRTDGNGSQTRSLNSERKMYPFGRAGLQ XRLAAGHPPVPPAAGLPVGAGPGALQGSGLAPGPPGQHLPPGASGKEA NT seq 3387 nt NT seq  +upstreamnt  +downstreamnt ctagcagtcggcggcggaggcggaggcggcgcgggcgagtctgttggcgccgagcggcgg gcggggccgggcggccggcgcgggctgcgggcgtgcgatgaggagttcgcgtgccccgag ctggaggcgctgttccgcggctacacgctgcggctggagcaggcggcgacgctgaaggcg ctggccrtgctcagcctgctggcgggcgcgctggccctggccgagctgctgggcgcgccg gggcccgcgcccggcctggctaagggctcgcaccccgtgcactgcgtgctcttcctggcg ctgctcgtggtcaccaacgtccgctcgctgcaggtgccccagctgcagcaggtcggccag ctcgcgctgctcttcagcctcaccttcgctctgctgtgctgtcccttcgcgctcggcggc cccgccggtgcccacgccggggcggcagcggtgccggcgacagccgatcagggagtctgg cagctccttttggtyaccttcgtgtcctatgccctgctgcccgtgcgcagcctgctggcc atcggcttcgggctcgtggtggccgcctcgcacttgctggtcacggctacgttggtcccc gccaagcgcccacgtctctggagaacgctgggtgccaacgctctgctcttcctyggtgtg aacgtgtatggcgtcttcgtgaggatcctggctgagcgcgcccagaggaaggccttcctg caggcccggaactgcattgaggaccggctgaggctggaggaygagaatgagaagcaggag cggctgctcatgagcctcctgcctcggaatgttgccatggagatgaaggaggacttcctg aagccccctgagaggattttccacaagatttacatccagcggcatgacaacgtgagcatc ctctttgcagacatcgtgggcttcacaggcttggcgtcacagtgcacggcccaggagctg gtgaaactcctcaaygagctcttygggaagtttgacgagctggccacagagaaccactgc cgccgcatcaagatcctgggagattgctactactgcgtgtctggcctcactcagcccaag actgaccacgcccactgctgtgtggagatgggcctggacatgatcgacaccatcacgtcc gtggctgaggccactgaggtggacttgaacatgcgtgtggggctgcacaccggcagggtc ctctgcggggtcctgggcctgcgtaagtggcagtatgatgtgtggtccaacgacgtgacc ctggccaacgtcatggaggctgccggcctgcctgggaaggttcacatcacaaagaccacc ctggcgtgcctgaatggtgactatgaggtggagccgggacacggacacgagaggaacagt tttctgaaaactcataacatygagaccttttttattgtgccctcgcatcggcgaaagata tttccagggctgattctctcagacataaaaccggccaagaggatgaagttcaagaccgtg tgctacctgctggtgcagctcatgcactgccggaagatgttcaaggccgagatccctttc tccaacgtcatgacctgtgaggaygacgacaagcggagggcactgagaacagcctcggaa aaactcagaaaccgctcgtctttctctacaaacgttgtccaaaccacccccggcacacgt gtcaacaggtacatcggccgcctcctggaagcccgccagatggagctggagatggcagac ctgaacttcttcaccctgaagtacaagcaagctgagcgagagcgaaagtaccaccagctt caggacgagtatttcaccagcgccgtggttctggctctcattctggccgccttattcggc cttgtctaccttctaataatcccacagagtgtggctgtcctgctcctgctggtgttctgc atctgcttcctggtggcctgtgtcctgtacctacacatcacccgggtccagtgttttcca gggtgcctgaccatccagatccgcaccgtcttgtgcatcttcatcgtggtcttaatctac tctgtggcccaaggctgtgtggtgggctgcctgccttggtcctngtgctccagtcccaac gggtccctggtggtcctgtcttctgggggccgggacccagtgctgcctgtcccgccctgc gagtctgcgccccatgccctgctgtgcggcctcgtgggcaccctcccgctggccatattc ctgcgggtctcctccttgccaaaaatgatcctgctcgccgtgctcaccacctcctacatc ctcgtcctggagctcagcgggtacacgaaggccatgggggccggtgccatctcagggcgc agcttcgagccgatcgtggccatcctgctattctcgtgcacgctggccctgcacgcccgg caggtggatgtcaagctgcggctggactacctctgggcggcccaggcagaggaggagcgg gatgacatggagaaagtgaagctggacaacaagaggattctcttcaacctcctgccagcc cacgttgcccagcacttcctaatgtccaaccctcgcaacatggacctgtattaccagtca tactcgcaggtgggggtcatgtttgcatccatccccaacttcaatgacttctacatcgag ctggatggcaacaacatgggggtggaatgtctacgccttctgaatgagatcatcgctgac tttgatgagctcatggacaaagacttttacaaggacctagagaagatcaagaccattggg agcacgtacatggctgctgtggggctggcgcccactgctgggaccaaggctaagaagtgc atctcctcccacctcagcacgttggcagattttgccatcgagatgtttgatgtcctggat gagatcaactaccagtcttataacgactttgtgctccgtgttggcatcaacgttggcccc gtggtggctggagtgatcggggctcgcaggccgcagtatgacatttgggggaacacggtc aatgtggccagtcggatggacagtaccggcgtccagggcaggatccaggtcacagaggaa gttcaccggctgctgcggcggggttcctaccgcttcgtgtgccgaggcaaagtcagtgtc aagggcaagggtgagatgctgacatacttcctggaaggcaggaccgatggaaatggctcc caaaccaggtccctgaactcagagcggaaaatgtatcctttcggaagagctggcctccag ascagactggctgcgggtcaccccccggtacctcctgcagccggcctcccagttggagct gggccaggggctctgcagggctcggggcttgccccaggccccccaggccaacacctgccc cctggagcctctgggaaggaggcttag

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