Bos indicus (zebu cattle): 109566382
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Entry
109566382 CDS
T04792
Symbol
ROCK2
Name
(RefSeq) rho-associated protein kinase 2 isoform X1
KO
K17388
Rho-associated protein kinase 2 [EC:
2.7.11.39
]
Organism
biu
Bos indicus (zebu cattle)
Pathway
biu04022
cGMP-PKG signaling pathway
biu04024
cAMP signaling pathway
biu04062
Chemokine signaling pathway
biu04071
Sphingolipid signaling pathway
biu04270
Vascular smooth muscle contraction
biu04310
Wnt signaling pathway
biu04360
Axon guidance
biu04510
Focal adhesion
biu04520
Adherens junction
biu04530
Tight junction
biu04611
Platelet activation
biu04670
Leukocyte transendothelial migration
biu04810
Regulation of actin cytoskeleton
biu04921
Oxytocin signaling pathway
biu05132
Salmonella infection
biu05135
Yersinia infection
biu05163
Human cytomegalovirus infection
biu05200
Pathways in cancer
biu05205
Proteoglycans in cancer
biu05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
biu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
109566382 (ROCK2)
04071 Sphingolipid signaling pathway
109566382 (ROCK2)
04024 cAMP signaling pathway
109566382 (ROCK2)
04022 cGMP-PKG signaling pathway
109566382 (ROCK2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
109566382 (ROCK2)
04520 Adherens junction
109566382 (ROCK2)
04530 Tight junction
109566382 (ROCK2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
109566382 (ROCK2)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
109566382 (ROCK2)
04670 Leukocyte transendothelial migration
109566382 (ROCK2)
04062 Chemokine signaling pathway
109566382 (ROCK2)
09152 Endocrine system
04921 Oxytocin signaling pathway
109566382 (ROCK2)
09153 Circulatory system
04270 Vascular smooth muscle contraction
109566382 (ROCK2)
09158 Development and regeneration
04360 Axon guidance
109566382 (ROCK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
109566382 (ROCK2)
05205 Proteoglycans in cancer
109566382 (ROCK2)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
109566382 (ROCK2)
09171 Infectious disease: bacterial
05132 Salmonella infection
109566382 (ROCK2)
05135 Yersinia infection
109566382 (ROCK2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
109566382 (ROCK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
biu01001
]
109566382 (ROCK2)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
biu03036
]
109566382 (ROCK2)
Enzymes [BR:
biu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.39 ROCK-subfamily protein kinase
109566382 (ROCK2)
Protein kinases [BR:
biu01001
]
Serine/threonine kinases: AGC group
DMPK family [OT]
109566382 (ROCK2)
Chromosome and associated proteins [BR:
biu03036
]
Eukaryotic type
Centrosome formation proteins
Kinases and associated factors
109566382 (ROCK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Rho_Binding
PH_MRCK
PH
C1_1
APH
Pkinase_C
Motif
Other DBs
NCBI-GeneID:
109566382
NCBI-ProteinID:
XP_019826253
LinkDB
All DBs
Position
11:89341074..89423422
Genome browser
AA seq
1387 aa
AA seq
DB search
MKAEDYDVVKVIGRGAFGEVQLVRHKASQKVYAMKLLSKFEMIKRSDSAFFWEERDIMAF
ANSPWVVQLFCAFQDDKYLYMVMEYMPGGDLVNLMSNYDVPEKWAKFYTAEVVLALDAIH
SMGLIHRDVKPDNMLLDKHGHLKLADFGTCMKMDETGMVHCDTAVGTPDYISPEVLKSQG
GDGYYGRECDWWSVGVFLFEMLVGDTPFYADSLVGTYSKIMDHKNSLCFPEDAEISKHAK
NLICAFLTDREVRLGRNGVEEIKQHPFFKNDQWNWDNIRETAAPVVPELSSDIDSSNFDD
IEDDKGDVETFPIPKAFVGNQLPFIGFTYYRENLLLSDSPSCKENDSIQSRKNEESQEIQ
KKLYTLEEHLSTEIQAKEELEQKCKSVNTRLEKVAKELEEEITLRKNVESTLRQLEREKA
LLQHKNAEYQRKADHEADKKRNLENDVNSLKDQLEDLKKRNQNSQISTEKVNQLQRQLDE
TNALLRTESDTAARLRKTQAESSKQIQQLESNNRDLQDKNCLLETAKLKLEKEFINLQSV
LESERRDRTHGSEIINDLQGRISGLEEDVKNGKILLAKVELEKRQLQERFTDLEKEKNNM
EIDMTYQLKVIQQSLEQEETEHKATKARLADKNKIYESIEEAKSEAMKEMEKKLSEERTL
KQKVENLLLEAEKRCSILDCDLKQSQQKINELLKQKDVLNEDVRNLTLKIEQETQKRCLT
QNDLKMQTQQVNTLKMSEKQLKQENNHLLEMKMSLEKQNAELRKERQDADGQMKELQDQL
EAEQYFSTLYKTQVRELKEECEEKTKLCKELQQKKQELQDERDSLAAQLEITLTKADSEQ
LARSIAEEQYSDLEKEKIMKELEIKEMMARHKQELTEKDATIASLEETNRTLTSDVANLA
NEKEELNNKLKEAQEQLSRLKDEEISAAAIKAQFEKQLLTERTLKTQAVNKLAEIMNRKE
PVKRGNDTDVRRKEKENRKLHMELKSEREKLTQQMIKYQKELNEMQAQIAEESQIRIELQ
MTLDSKDSDIEQLRSQLQALHIGLDSSSIGSGPGDTEADDGFPVHITQSHTMESMSFTYQ
RSSTSLNIATKPSSSHMLLDSDSDSEEESVPYLPISSEPNESRLEGWLSLPVRNNTKKFG
WVKKYVIVSSKKILFYDSEQDKEQSNPYMVLDIDKLFHVRPVTQTDVYRADAKEIPRIFQ
ILYANEGESKKEQEFPVEPVGEKSNYICHKGHEFIPTLYHFPTNCEACMKPLWHMFKPPP
ALECRRCHIKCHKDHMDKKEEIIAPCKVYYDISSAKNLLLLANSTEEQQKWVSRLVKKIP
KKPPAPDPFARSSPRTSMKIQQNQSIRRPSRQLAPNKPRLLDLAFKDWDWSFDDVDGGDE
DDDVFDF
NT seq
4164 nt
NT seq
+upstream
nt +downstream
nt
atgaaggcagaagactacgatgttgtaaaagttatcggaagaggtgcttttggtgaagtc
cagttggttcgtcataaggcatcacagaaagtttatgctatgaagcttcttagtaagttt
gaaatgataaaaagatcagattctgcttttttctgggaggaaagagatattatggccttt
gccaacagtccctgggtggttcagctcttttgtgcctttcaagatgataagtatctgtac
atggtaatggagtacatgcctggtggagaccttgtaaaccttatgagtaactatgatgta
cctgaaaaatgggccaaattttatactgctgaagttgttcttgctttggatgccatacac
tccatgggtttaattcacagagatgtgaagcctgacaacatgctcttggataaacatggg
catctaaaattagcagattttggcacatgtatgaagatggatgaaacaggcatggtgcat
tgtgatacagcagttggaacacccgattatatatcacccgaggtcctgaaatcacaaggg
ggtgatggttactatgggcgagaatgtgattggtggtccgtgggtgttttcctttttgaa
atgctggtgggggatactccattttatgcagattcacttgtaggaacatatagcaaaatt
atggatcataaaaactcactatgtttccctgaagatgcagaaatttctaaacatgcgaag
aatctcatctgtgccttcttaacagatagggaggtacgccttggaagaaacggggtagaa
gaaatcaaacaacatcctttctttaagaatgatcagtggaattgggataacataagagag
actgcagctcctgtggtacctgaactcagcagtgacatagacagcagcaattttgatgac
attgaagatgataaaggagatgtagaaaccttcccaattcccaaggcttttgtgggaaat
cagctaccttttataggatttacctactacagagaaaatttgctactaagtgactctcca
tcttgtaaagaaaatgactcaattcaatcaaggaagaatgaagagagtcaagagattcag
aaaaaactgtacacattagaagaacaccttagcactgagattcaggccaaagaggaacta
gaacagaagtgcaagtctgttaatactcgcttagagaaagtggcaaaggagttagaagaa
gagattaccttaaggaaaaatgtggaatcaacattaagacaattagaaagagaaaaagca
cttcttcagcacaaaaatgcagaatatcagcggaaagctgatcatgaagcagacaagaag
cgaaatttggagaatgatgttaacagtttaaaagatcagcttgaagatttgaaaaaaaga
aatcagaactctcagatatccactgagaaagtgaatcaactccagagacaactggatgaa
accaatgctttgctgcgaacagaatctgatactgcagcccggttaaggaaaacacaggca
gaaagttcaaaacagattcagcagctggaatctaacaatagagatctacaagacaaaaat
tgcctgctggagactgccaagttaaaacttgaaaaggaatttatcaatcttcagtcagtt
ctagaatctgaaaggagggaccgaacccatggatcagagattattaatgatttacaaggt
agaatatctggcctagaagaagatgtaaagaatggtaaaatcttattagcaaaagtagag
ctggagaagagacaactacaggagagatttactgatttggaaaaggaaaagaacaacatg
gaaatagatatgacataccaactaaaagtcatacagcaaagtttagaacaagaagaaact
gaacataaggctacaaaagcacggcttgcagataaaaacaagatttatgaatccattgaa
gaagctaaatcagaagccatgaaagaaatggagaaaaagctctcggaggaaagaacttta
aaacagaaagtagagaacttgttgctggaggctgagaaaagatgctctatattagactgt
gacctcaaacagtcacagcagaaaataaatgaactcctcaaacagaaagatgtgctaaat
gaggatgttagaaacttgacattaaaaatagaacaggaaactcagaagcgctgccttaca
caaaatgacttgaagatgcaaacacagcaagttaacacactaaaaatgtcagaaaagcag
ttaaagcaagagaataatcatctcctagaaatgaaaatgagcttggaaaaacagaatgct
gaacttcgaaaagaacgtcaagatgcagatggacagatgaaagagctccaggatcagctt
gaagcagagcagtatttctcaaccctctataaaacacaggttagggaacttaaggaagaa
tgtgaagaaaagaccaaactttgtaaagaattacagcagaagaagcaggaattacaggat
gaaagggactccttggctgctcaactggagattaccttaaccaaagcagattctgagcaa
ctggctcgttcaattgctgaggaacagtattctgatttggaaaaagagaagatcatgaaa
gagctggagatcaaagagatgatggctcgacacaaacaggaactcaccgaaaaagatgct
actattgcgtctcttgaagaaactaataggacactaactagtgatgttgccaatcttgca
aatgagaaagaagaattaaataacaaactgaaggaagcccaagagcaactatcaaggttg
aaagatgaagaaataagtgcagcagctattaaagcacaatttgagaagcagctgttaaca
gagaggacactcaaaactcaagctgtgaataagttggctgagatcatgaatcgaaaggaa
cctgttaagcgtggtaatgacacagatgtgcggagaaaagaaaaggagaatagaaagcta
catatggaacttaaatctgaacgcgaaaaactgacccagcagatgatcaagtatcagaaa
gaactgaatgaaatgcaggctcaaatagctgaagagagtcagattcgaattgaactacag
atgacactggacagtaaggacagtgacattgagcagctgcgctcccagctccaggccttg
cacattggtttggatagttccagtataggcagtggaccaggggatactgaagctgatgac
gggtttccagttcatatcactcagtcacacactatggaatccatgtcattcacctaccaa
cgttcctccacttctctcaatattgccactaagccttccagttctcatatgcttcttgac
tctgattctgactcagaagaagaatctgttccttacttacctatttcatcggaacctaat
gaatcaagactagaaggatggctttcattgcctgtgcgaaacaacactaagaaatttgga
tgggttaaaaagtatgtgattgtaagcagtaagaagatccttttctatgacagtgaacaa
gataaagaacaatctaatccttacatggttttagatatagacaagttatttcatgtccga
ccagttacacagacagatgtatatagagcagatgctaaagaaattccaaggatattccag
attctgtatgccaacgaaggagaaagtaagaaggaacaagaatttccagtggagccagtg
ggagaaaaatcaaattatatttgccacaagggacatgaatttattcctactctgtatcat
ttcccaaccaactgtgaggcatgtatgaagccattgtggcacatgtttaaaccccctcct
gctttagagtgccgtcgctgtcatattaaatgtcataaagatcacatggacaaaaaggag
gaaattatagcgccttgcaaagtgtattatgatatttcatcggcaaagaatctattgtta
ttggcaaattctacagaagagcagcaaaagtgggttagtcggttagtgaaaaaaatacct
aaaaagcctccagctccagacccttttgcacggtcatctcctagaacgtcaatgaaaata
caacaaaaccagtctattcgacggccaagtcgacaacttgctccaaacaaaccaagattg
cttgatttggcatttaaagactgggattggtcatttgatgatgttgatggtggtgatgag
gatgacgatgtttttgatttctga
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integrated database retrieval system
