Bos indicus (zebu cattle): 109572368 Help Entry 109572368         CDS       T04792                                  Symbol LCK Name (RefSeq) tyrosine-protein kinase Lck   KO K05856   lymphocyte cell-specific protein tyrosine kinase [EC:2.7.10.2] Organism biu  Bos indicus (zebu cattle) Pathway biu04064   NF-kappa B signaling pathway biu04380   Osteoclast differentiation biu04650   Natural killer cell mediated cytotoxicity biu04658   Th1 and Th2 cell differentiation biu04659   Th17 cell differentiation biu04660   T cell receptor signaling pathway biu05135   Yersinia infection biu05166   Human T-cell leukemia virus 1 infection biu05235   PD-L1 expression and PD-1 checkpoint pathway in cancer biu05340   Primary immunodeficiency Brite KEGG Orthology (KO) [BR:biu00001]  09130 Environmental Information Processing   09132 Signal transduction    04064 NF-kappa B signaling pathway     109572368 (LCK)  09150 Organismal Systems   09151 Immune system    04650 Natural killer cell mediated cytotoxicity     109572368 (LCK)    04660 T cell receptor signaling pathway     109572368 (LCK)    04658 Th1 and Th2 cell differentiation     109572368 (LCK)    04659 Th17 cell differentiation     109572368 (LCK)   09158 Development and regeneration    04380 Osteoclast differentiation     109572368 (LCK)  09160 Human Diseases   09161 Cancer: overview    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     109572368 (LCK)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     109572368 (LCK)   09171 Infectious disease: bacterial    05135 Yersinia infection     109572368 (LCK)   09163 Immune disease    05340 Primary immunodeficiency     109572368 (LCK)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:biu01001]     109572368 (LCK)   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:biu03036]     109572368 (LCK) Enzymes [BR:biu01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      109572368 (LCK) Protein kinases [BR:biu01001]  Non-receptor tyrosine kinases   SRC family    109572368 (LCK) Chromosome and associated proteins [BR:biu03036]  Eukaryotic type   Centrosome formation proteins    Kinases and associated factors     109572368 (LCK) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase SH2 SH3_1 SH3_2 SH3_9 ABC1 SH2_1 Haspin_kinase Kdo SH3_16 Motif Other DBs NCBI-GeneID:  109572368 NCBI-ProteinID:  XP_019834692 UniProt:  A0A6P5DC96 LinkDB All DBs Position 2:complement(125362289..125383273) Genome browser AA seq 509 aa AA seqDB search MGCSCSSNPEDDWMENIDVCENCHYPIVPLDGKTTLPMRNGSEVRDPLVTYEGSNPPASP LQDNLVIALHSYEPSHDGDLGFEKGEQLRILEQNGEWWKAQSLTTGQEGFIPFNFVAKAN SLEPEPWFFKTLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQTQGEVVKH YKIRNLDKGGFYISPRVTFPGLHELVRHYMNTSDGLCTRLSRPCQTQKPQKPWWEDEWEV PRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQHQRL VRLYAVVTQEPIYIITEYMENGSLVDFLKTSEGIKLTINKLLDMAAQIAEGMAFIEEQNY IHRDLRAANILVSHSLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIK SDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEELYQLMMLCWKER PEERPTFDYLRSVLEDFFTATEGQYQPQP NT seq 1530 nt NT seq  +upstreamnt  +downstreamnt atgggctgtagctgcagctcaaacccagaagatgactggatggaaaacatcgatgtatgt gaaaactgccactaccccatagtcccactggatggcaagaccacgctgcccatgcggaat ggctctgaagtgcgtgatccactggtcacctacgagggatccaaccccccagcttctcca ctgcaagacaacctggttatcgccctgcacagctatgagccttctcacgacggagacctg ggcttcgagaagggtgaacagctccgtatcctggagcagaacggcgagtggtggaaggcg cagtccctgaccacgggccaggaaggtttcatccccttcaactttgtggccaaagcgaac agcctggagcccgaaccctggttcttcaagactctgagccgcaaggacgcggagaggcag ctcctggcgccggggaacacgcacggctccttcctgatccgggagagcgagagcacggcg ggatcgttttcactgtcggtccgggacttcgaccagacccagggagaagtggtgaaacat tacaagatccgtaacctggacaaaggcggcttctacatctcgccccgcgtcacttttccc ggcttgcacgagctggtccgccattacatgaatacttcggacgggctgtgcacacggttg agccgcccctgccagacccagaagccccagaagccgtggtgggaggatgagtgggaggtt cccagggagactctgaagctggtggagcggctgggggctggccagttcggagaggtgtgg atggggtactacaacgggcacacgaaggtggcagtcaagagcctgaagcagggcagcatg tcccccgatgccttcctggccgaggccaacctcatgaagcagctgcaacaccagaggctg gtccggctctacgcggtggtcacccaggagcccatctacatcatcacggaatatatggag aacggaagcctggtggattttctcaagacctccgaaggcatcaagctgactatcaacaaa ctcttggacatggcagcccaaattgcagagggcatggcattcattgaagagcagaattat atccaccgtgacttgagggctgccaacatcctggtgtcccatagcctgagctgcaagatt gcggactttggtctagcacgcctcattgaggacaacgagtacacagccagggagggtgcc aagtttcccattaagtggacagcaccagaagccattaactatgggacattcaccatcaag tcggacgtgtggtcttttgggatcctgctgacggagattgtcactcatggtcgcatccct tacccagggatgaccaatcctgaggtgattcagaacctggagcgaggctaccgcatggta cgacctgacaactgcccggaggagttgtaccagcttatgatgctgtgctggaaggagcgc ccggaagaacggcccacctttgactacctgcgcagcgtgttggaggacttcttcacagcc acggagggccagtaccagccccagccctga

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