Bos indicus (zebu cattle): 109574004
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Entry
109574004 CDS
T04792
Symbol
ALOX12
Name
(RefSeq) arachidonate 12-lipoxygenase, 12S-type isoform X1
KO
K00458
arachidonate 12-lipoxygenase [EC:
1.13.11.31
]
Organism
biu
Bos indicus (zebu cattle)
Pathway
biu00590
Arachidonic acid metabolism
biu01100
Metabolic pathways
biu01523
Antifolate resistance
biu04726
Serotonergic synapse
biu04750
Inflammatory mediator regulation of TRP channels
Brite
KEGG Orthology (KO) [BR:
biu00001
]
09100 Metabolism
09103 Lipid metabolism
00590 Arachidonic acid metabolism
109574004 (ALOX12)
09150 Organismal Systems
09156 Nervous system
04726 Serotonergic synapse
109574004 (ALOX12)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
109574004 (ALOX12)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
109574004 (ALOX12)
Enzymes [BR:
biu01000
]
1. Oxidoreductases
1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
1.13.11 With incorporation of two atoms of oxygen
1.13.11.31 arachidonate 12-lipoxygenase
109574004 (ALOX12)
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Motif
Pfam:
Lipoxygenase
PLAT
Motif
Other DBs
NCBI-GeneID:
109574004
NCBI-ProteinID:
XP_019837237
UniProt:
A0A6P5DJ54
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Position
19:27158338..27172679
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AA seq
663 aa
AA seq
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MGRYRILVATGASLFAGSHNRVQLWLVGARGETELELQLRPARGQKEEFEHEVPEDLGPL
QFVKLRKHHSLVEDAWFCDRITVRGPGACEEAAFPCYRWVQGDGVLCLPEATARLAGNNA
LDVFQRHREKELKERHKIYRWATWKEGLPLTIAAGSEDDLPANMRFHEEKRLDFEWTLKA
GALEMVLKRVYTLLSSWTSLEDFDLIFWGQKSPLAEKVHQCWRDDELFGYQFLNGANPML
LRRCTSLPSRLVLPSGMEELRAQLERELQNGSLFEADFILLDGIPANVIRGEKQYLAAPL
VMLKMDPSGKLLPMVIQIQPPSPISPTPPLFLPSDPPLAWLLAKTWVRNSDFQLHQLQYH
LLNTHLLAEVIAVATMRCLPGLHPVFKLLMPHIRYTMEINTRARTQLISDGGIFDKAVST
GGGGHVHLLRRALAQLTYRSLCPLDDLADRRLLGTPGALYACDALRLWEITARYVEGIVH
LFYHGDDVVKGDPELQAWCREITEVGLRQAQERGFPVSFQSQNQLCHFLTMCVFTCTAQH
GAINQGQLDWYAWVPNAPCTMRMPPPTTKEDVTMATVMGSLPDVRQACLQMAITWHLGRR
QPDMVPLGHHKEKYFSDPKAKSVLNQFQTDLENLEREITARNEQLDLPYEYLKPSHIENS
VTI
NT seq
1992 nt
NT seq
+upstream
nt +downstream
nt
atgggccgctaccgcatcctcgtggccaccggggcctcgctcttcgccggctcgcacaac
cgcgtgcagctgtggctggtcggggcgcgcggggaaacggagctggagctgcagctgcgg
ccggcgcggggccagaaggaggagtttgaacacgaagttccggaggacctggggccgttg
cagttcgtgaagttgcgcaaacaccactccctggtggaggacgcgtggttctgcgaccgc
atcacggtgcggggccctggagcctgcgaggaggccgcgttcccgtgctaccgctgggtg
cagggtgacggcgtgctgtgcctgccagaggccaccgcccgcctggcaggaaacaatgca
ttggacgtgttccagagacatcgagagaaggagctgaaagaaagacataagatataccgc
tgggccacctggaaggaagggttacctctgacaatagctgcaggctctgaagacgatcta
cctgcaaatatgagattccacgaggagaagaggctggactttgagtggacactgaaggcg
ggggctctggagatggtcctcaaacgtgtttacaccctcctgagctcctggaccagtctg
gaggattttgatctcatcttctggggccagaagagccccctggctgagaaggttcaccag
tgctggcgggacgatgagttgtttggctaccagtttctcaatggcgccaaccccatgctg
ttgagacgctgcacctctctgccctcccggctggtgctgccctcggggatggaggagcta
cgggcccagctggagagagaactccagaacggttccctgtttgaggctgatttcatcctc
ctggacggaattccagccaatgtgatccgaggagagaagcagtacctggctgcccccctc
gtcatgctcaagatggaccccagtgggaagctgctacccatggtcatccagatccagcct
cccagccccatctccccgacccccccattgttcctgccctcggatcctccacttgcctgg
ctcctggcaaagacctgggtccgaaattcagatttccaactgcatcagctccaataccat
ctgctcaacacccatctgctggctgaggtcatcgctgtggccaccatgaggtgcctccca
gggctgcaccctgtcttcaagctcctgatgccacacatccgctacacgatggaaatcaac
accagggcacggactcagctcatctcagacggaggcatatttgataaagcagtgagcacc
ggtggagggggccatgtgcacttgctccgccgggccctggctcagctgacctaccgctcc
ctctgtcctcttgatgatctggctgatcgccgcctgctgggaaccccgggtgctctctac
gcctgtgatgctttacggctctgggaaatcactgcccggtatgtggaggggattgtccac
ctcttctaccatggggacgacgttgtaaaaggggaccctgagctgcaggcctggtgtcgg
gagatcactgaggtggggctgcgccaggcccaggagcgaggcttccctgtctccttccag
tcccagaatcaactctgccatttccttaccatgtgtgtcttcacgtgcactgctcagcat
ggggccatcaaccagggccagctggactggtatgcctgggtccctaatgccccttgcaca
atgcggatgcccccacccaccactaaggaagatgtgacaatggccacagtgatgggctcr
ctacctgatgtccgacaagcctgtcttcaaatggccatcacatggcatctgggtcgccgt
cagccagacatggtgcctctggggcatcacaaagaaaagtatttctcagaccccaaggcc
aaatctgtactaaaccaattccaaacagatctggaaaacttggaaagggaaattacagcc
cgcaatgagcaacttgacctgccctatgaatacctaaagcccagccacatagagaacagc
gtcactatttga
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