Bubalus kerabau (carabao): 129627027
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Entry
129627027 CDS
T11435
Symbol
HSD11B1L
Name
(RefSeq) hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X1
KO
K15680
corticosteroid 11-beta-dehydrogenase isozyme 1 [EC:
1.1.1.146
]
Organism
bke Bubalus kerabau (carabao)
Pathway
bke00140
Steroid hormone biosynthesis
bke00980
Metabolism of xenobiotics by cytochrome P450
bke01100
Metabolic pathways
bke05204
Chemical carcinogenesis - DNA adducts
Module
bke_M00109
C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
Brite
KEGG Orthology (KO) [BR:
bke00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
129627027 (HSD11B1L)
09111 Xenobiotics biodegradation and metabolism
00980 Metabolism of xenobiotics by cytochrome P450
129627027 (HSD11B1L)
09160 Human Diseases
09161 Cancer: overview
05204 Chemical carcinogenesis - DNA adducts
129627027 (HSD11B1L)
Enzymes [BR:
bke01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.146 11beta-hydroxysteroid dehydrogenase
129627027 (HSD11B1L)
SSDB
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Paralog
GFIT
Motif
Pfam:
adh_short
adh_short_C2
DUF1776
Motif
Other DBs
NCBI-GeneID:
129627027
NCBI-ProteinID:
XP_055402553
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All DBs
Position
1
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AA seq
324 aa
AA seq
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MWAALSPTADPGRAMKVLLLTGLGALFFAYYWDDNFDPASLQGARVLLTGVSAGIGEELA
YHYARLGSHLVLTAHTEALLQQVVGNCRKLGAPKVFYIAADMASPEVPERVVQFALDKLG
GLDYLVLNHLGAAPAGTRVRSSQSTRWLMQAFAPSPSGLGFLLRLVTRSRHLQMNFLSYV
QLTSSALPSLTDSKGSLVVVSSLLGRVPTSFSSPYSAAKFALDSFFSSLRRELDVQEVNV
AITMCVLGLRDRASAAEGVRGITRVRAAPGPKAALAVIRGGATRASGVFYPWRFHLLCLL
RSWMPHSRAWFVRQELNITTPAAA
NT seq
975 nt
NT seq
+upstream
nt +downstream
nt
atgtgggctgccctctctcccactgcagacccagggagggccatgaaggtgctgctcctt
acagggctgggagccctgttctttgcctattactgggatgacaactttgacccagccagc
ctccaaggagcccgtgtgctactgaccggagtcagtgccggcataggggaagagctggcg
tatcactacgcgcgcctgggctcccacctcgtgctcactgcccacaccgaagctctgctg
cagcaggtggtagggaactgccggaagctgggcgctcccaaggtcttctacatcgctgcg
gacatggcctcccctgaggtgcccgagcgcgtggtgcagtttgcgctggacaagctggga
gggctggactacctggtgctgaaccacctcggcgccgccccagcaggcacgcgggtccgc
agctcccagtcgacacgttggctcatgcaggccttcgccccttccccatctgggcttgga
ttcctcctccgcctggtgactcgcagtcgccacctccagatgaacttcctaagttatgtg
caattgacttcttcggcgctgccaagcctgactgacagcaagggctccctggtggtggta
tcctcattgctcggccgggtgcccacttccttctccagcccctactcggcagccaagttc
gcgctggacagcttcttcagttctctgcggcgggagctggacgtgcaggaagtgaacgtg
gccattaccatgtgtgttctgggtctccgagatcgtgcctcagccgccgaaggagtcagg
ggcatcacgagggtcagggcggctccagggcccaaggcagccctggccgtaatccgcgga
ggcgccacgcgtgcctccggggtcttctacccgtggcgcttccacctgctctgcctgctc
cgcagttggatgccacactcaagggcctggttcgtccgccaggagctcaatataacgacg
cccgctgctgcctga
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