Bubalus kerabau (carabao): 129648938
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Entry
129648938 CDS
T11435
Symbol
BRCA1
Name
(RefSeq) breast cancer type 1 susceptibility protein isoform X1
KO
K10605
breast cancer type 1 susceptibility protein [EC:
2.3.2.27
]
Organism
bke Bubalus kerabau (carabao)
Pathway
bke01524
Platinum drug resistance
bke03440
Homologous recombination
bke03460
Fanconi anemia pathway
bke04120
Ubiquitin mediated proteolysis
bke04151
PI3K-Akt signaling pathway
bke05206
MicroRNAs in cancer
bke05224
Breast cancer
Brite
KEGG Orthology (KO) [BR:
bke00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
129648938 (BRCA1)
09124 Replication and repair
03440 Homologous recombination
129648938 (BRCA1)
03460 Fanconi anemia pathway
129648938 (BRCA1)
09130 Environmental Information Processing
09132 Signal transduction
04151 PI3K-Akt signaling pathway
129648938 (BRCA1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
129648938 (BRCA1)
09162 Cancer: specific types
05224 Breast cancer
129648938 (BRCA1)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
129648938 (BRCA1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
bke01009
]
129648938 (BRCA1)
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:
bke04121
]
129648938 (BRCA1)
03036 Chromosome and associated proteins [BR:
bke03036
]
129648938 (BRCA1)
03400 DNA repair and recombination proteins [BR:
bke03400
]
129648938 (BRCA1)
Enzymes [BR:
bke01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.27 RING-type E3 ubiquitin transferase
129648938 (BRCA1)
Protein phosphatases and associated proteins [BR:
bke01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
129648938 (BRCA1)
Ubiquitin system [BR:
bke04121
]
Ubiquitin ligases (E3)
Single Ring-finger type E3
Other single Ring-finger type E3
129648938 (BRCA1)
Multi subunit type E3
BRCC complex
129648938 (BRCA1)
Chromosome and associated proteins [BR:
bke03036
]
Eukaryotic type
Centrosome formation proteins
Centrosome duplication proteins
Regulators of centriole replication
129648938 (BRCA1)
DNA repair and recombination proteins [BR:
bke03400
]
Eukaryotic type
DSBR (double strand breaks repair)
HR (homologous recombination)
BRCA1-core complex
129648938 (BRCA1)
BRCA1-A complex
129648938 (BRCA1)
BRCA1-B complex
129648938 (BRCA1)
BRCA1-C complex
129648938 (BRCA1)
BRCA complex
129648938 (BRCA1)
FA (Fanconi anemia) pathway
Downstream FA components
129648938 (BRCA1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Other DBs
NCBI-GeneID:
129648938
NCBI-ProteinID:
XP_055431749
LinkDB
All DBs
Position
4:21064505..21136141
Genome browser
AA seq
1859 aa
AA seq
DB search
MDLSADHVEEVQNVLNAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQ
CPLCKNDITKRSLQESTRFSQLVEELLKIIHAFELDTGLQFANSYNFSRKENNSPEHLKE
EVSIIQSMGYRNRAKRLWQSEPENPTLQETSLTVELSNLGIVRSLRTKQQTQSQNKSVYI
ELGSDSSEDTVNKASYFSVGDHELLEITPQGAKAKTNLNPAKKAACEFSEKDITNTEHHQ
LSIKDLITSQKHATETHPEKYQGISVSDFHVEPCGTDTHASSLQHENSSLLLTENRLNVE
KAEFCNKSKQPVLVKSQQSRWAESKGTCKDRQIPSTEKKIVLNTDPLYRRKELRKQKPAC
PDSPGDSQDVPWVTLNNSIQKVNDWFSRSDEILTSDDSCDGGSESNNEVAGAVEIPNKVD
GYSGSSEKINLMASDPHGTLIHERVHSKPVESNIEDKIFGKTYRRKSSLPNFSHIAEDLI
LGAFTVEPQITQEQPLTNKLKCKRRGTSGLQPEDFIKKVDLTIVPKTPEKMIEGTDQTEQ
KRHRMNITSDGHENKTKHDYVHKEQNANPTESLEKESVFRTEAEPISISISNMELELNIH
SSKAPKNRLKRKSSTRKIPELELVVSRNPSPPNHTELPIDSSSSNEEMKKKHSSQMPVRQ
SQKLQLMGDKEPIAGAKKNNKTYEQISKRLASDAFPELNLTNTPGYFTNCCSKPEEFVHP
SLQREENLGAIQVSNSTKDPKDLILRGGKALQIERSVESTNISLVPDTDYGTQDSISLLE
AKTPEKAKTAPHPCVSLCAAIENPKELIHRDFKDTKNNTEGFQDLLGHDVNYVIQETSGE
MEDSELDTQYLQNTFKVSKRQTFALFSNPGNPQKECATVFAHSGSLRDQSPRDPLKCRQK
EDSRGKSESKSQHVQAIYTTVHFPVADQKDRTPGDDAKCSAKEVTRVCQSSQLRGHKTEL
VFANKQGVSEKPNLIPSLSPIKSSVKTICKKSPSEKFEEPVTSPEKTLGSESIIQSAVST
ISQNNIQESTFKEVSSSSVNEVGSSTNEVGSSINEVGSSGENIQAEPGRNREPKLRALLR
LGLMQPEVYKQSLLVSNCHHPEIKRQGENEDMLQAVKADFSPCLISDNLEQPTGSRHASQ
VCSETPDNLLNDDEIKENSHFAESDIKERSAVFSESVQKGEFRGSPGPFTHTHLAQGHQR
GAGKLESEETVSSEDEELPCFQQLLFGKVTNTLSPSTGCNTVATEATVSKETEENLESLK
SGLNDCSGQVTLAKVSQEHHLNEEARCSGSLFSSQCSAMEDLTTNTNTQDPFLMFERPSK
QVYQSESEEVLSDKELVSDDEERETGLEEDSCQEEQSVDSDLGEAVSDHVSETSLSEDCV
GLSSQSDILTTQQRDTMQDNLLKLQQEMAELEAVLERHGSQPSLSSASLTADSRGPEHLL
NLEQDTSERAILTSEKSRDYSRSQNPESLSADKFPVSLDSSTNKNKEPGMERSSPSKFQL
SDNRWYMHSSRSLQDRNCPSQKEPINVADMEEQQLAKCEAQDLMGSFLPRQDQEGTPYLK
SGISLFSHEPESDPSEDRAPEPAHVHSMPPSASALKLSQFRVEESTKNPAAAHITNTTGC
CNLREESVSKEKPEVISSTERSNKRLSMVASGLTPKELMLVQKFARKHHVTLTNLITEET
THVIMKTDPEFVCERTLKYFLGIAGGKWVVSYFWVTQSIKERKMLDEHDFEVRGDVVNGR
NHQGPKRARESRDKKIFKGLEICCYGPFTNMPTDQLEWMVQLCGASVVKEPSSFTPGQGT
HPVVVVQPDAWTEDAGFHVIGQMCEAPVVTREWVLDSVALYQCQELDTYLVPQVAQSCC
NT seq
5580 nt
NT seq
+upstream
nt +downstream
nt
atggatttatctgcggatcatgttgaagaagtacaaaatgtccttaatgctatgcagaaa
atcttagagtgtccaatatgtctggagttgatcaaagagcctgtctctacaaagtgtgac
cacatattttgcaaattttgtatgctgaaacttctcaaccagaagaaagggccttcacaa
tgtcctttgtgtaagaatgatataaccaaaagaagcctacaagaaagtacaagatttagt
caacttgttgaagagctgttgaagatcattcatgcttttgagcttgacacaggattgcag
tttgcaaacagctataacttttcgagaaaggaaaataactctcctgagcatctgaaggag
gaagtttctataatccaaagtatgggctaccggaaccgggccaaaagactttggcagagt
gaacctgaaaatcctaccttgcaggaaaccagtcttactgtcgaactctctaaccttgga
attgtcagatctctgagaacaaagcagcagacacaatctcagaataagtccgtctacatt
gaattgggatctgattcttctgaagacacagttaataaggccagttatttcagtgtggga
gaccatgaattgttagaaatcacccctcaaggagccaaggccaagacaaatttgaatcct
gcaaaaaaggctgcttgtgagttttctgagaaggacataacaaatactgaacatcatcaa
ctcagtattaaagatctgatcacctcccagaagcatgcaactgagacgcatccagaaaag
tatcagggtatttctgtttcagactttcacgtggagccatgtggcacagatactcatgcc
agctcattacagcatgagaacagcagtttattgctcactgaaaacagactgaatgtagaa
aaggctgaattctgtaataaaagcaaacagcctgtcttagtaaagagccaacagagcaga
tgggctgaaagtaagggcacatgtaaggataggcagattcccagcactgagaaaaagata
gttctgaatactgatcccctgtacagaagaaaagaactgcgtaagcagaaacctgcatgc
cctgacagtcctggagattcccaagatgttccttgggtaaccctgaataatagcatacag
aaagttaatgactggttttccagaagtgatgaaatattaacttctgacgactcgtgcgat
ggggggtctgaatcaaataatgaagtagctggtgcagtggaaattccaaataaagttgat
ggatattcaggttcttcagagaaaatcaacttaatggccagtgatcctcatggtacttta
atacacgaaagagtccactccaaaccagtagagagtaatattgaagataaaatatttggg
aaaacctatcggaggaagtcaagtctccctaacttcagccacatagctgaagatctaatt
ctaggcgcatttactgtagaacctcagataacacaagagcagcccctcacaaataaacta
aaatgtaaaaggagaggtacatcaggccttcagcctgaggattttatcaagaaagtcgat
ttgacaattgttccaaagactcctgaaaagatgattgagggaactgaccaaacagagcag
aaacgtcacaggatgaatattactagtgatggtcatgagaataaaacaaaacatgattat
gttcataaagagcaaaacgctaacccaacagaatcattggaaaaagaatctgttttcaga
actgaggctgaacctataagcatcagtataagcaatatggaactagaattgaatatccac
agttcaaaagcacctaagaataggctgaagaggaagtcctctaccaggaaaattcctgaa
cttgaactagtagtcagtagaaacccaagtccacctaatcatactgagctaccaattgat
agcagttctagcaatgaagagatgaagaaaaaacattctagccaaatgccagttaggcag
agccaaaagcttcaactcatgggagataaagaacctatagctggagccaagaagaataac
aaaacatatgaacaaataagtaaaagacttgctagtgatgcttttccagaactaaattta
acaaacacacctggttattttactaactgttgtagtaaacctgaagagtttgttcatcct
agccttcaaagagaggagaacctaggagcaattcaagtgtcgaatagtaccaaagacccc
aaagatctgatattaagaggaggaaaagctttgcaaattgaaagatctgtagagagtacc
aatatttccttggttcctgatactgattatggcactcaggatagtatctcattactagaa
gctaaaaccccagaaaaggcaaagactgcaccacatccatgtgtgagtctgtgtgcagca
atcgaaaaccccaaggaacttatccatagggattttaaagataccaaaaacaacacagag
ggctttcaggatctactgggacatgacgttaactacgtcattcaggagacaagcggagaa
atggaagacagtgaacttgatacacagtatttgcagaatacgttcaaggtttcaaagcgt
cagacatttgctctgttttccaatccaggaaatccacaaaaggaatgtgccacagtcttt
gcccactcggggtccttaagggatcaaagtccaagagaccccctcaaatgtagacaaaaa
gaagacagtcggggaaagagtgagtctaaaagccagcatgtacaggccatttatacaaca
gtgcactttcctgtggctgatcagaaagataggacgccaggtgacgatgccaaatgtagc
gcaaaagaagtaactagggtttgtcagtcatcacagttgagaggtcacaaaactgaactt
gtttttgcaaataaacaaggggtttcagaaaagccaaatcttataccatcactttctccc
atcaagtcatctgttaaaaccatatgtaagaaaagcccgtcagagaagtttgaggaacct
gtaacgtcacctgaaaaaacattgggaagtgaaagcatcattcaaagtgcagtgagcaca
atcagccaaaataacattcaagaaagcacttttaaagaagtcagctcaagcagtgttaat
gaagtaggttccagtactaatgaagtaggctctagtattaatgaagtaggttccagtggt
gaaaacattcaagcagaaccaggtagaaacagagaacctaaattaagagctttactcaga
ttaggtcttatgcaacctgaagtctataagcaaagtcttcttgtaagtaactgtcaccat
cctgaaataaaaaggcaaggagaaaatgaggacatgcttcaggctgttaaggcagatttc
tccccatgtctaatttcagataacctcgaacaacctacaggaagccgtcatgcttctcag
gtttgttctgagacacctgacaacttgttaaatgatgatgaaataaaagaaaatagccac
tttgctgaaagtgacattaaggaaagatctgctgtttttagtgaaagtgtccaaaaagga
gaattcagagggagccctggccctttcacccatacacatttggctcagggtcaccaaaga
ggggctggcaaactagagtcagaagagactgtgtctagtgaggatgaagagcttccctgc
ttccaacagttattgtttggtaaagtaaccaatacactgtctccatctaccggatgtaac
acggttgccactgaggcaacagtgtctaaggaaacagaggagaacctagaatcattgaag
agtggcttaaatgactgcagtggccaggtaacattagccaaggtgtcccaggaacatcac
cttaatgaggaagcaagatgttctggtagcttattttcctcacagtgcagtgcaatggaa
gacttgaccactaatacaaacacccaggatcctttcttgatgtttgagcgtccttccaaa
caagtgtatcagtctgaaagcgaggaagttctgagtgacaaggaattggtttcagatgat
gaagaaagggaaactggcttggaagaagatagttgccaagaagagcagagtgtggattca
gacttaggtgaagcagtatctgaccatgtgagtgaaacaagcctctctgaagactgtgtg
gggctgtcctctcagagcgatatcttaaccactcagcagagggataccatgcaagataac
ctactaaagctccagcaggaaatggccgagctggaagctgtgttagagcggcacgggagc
cagccttccctcagctctgcttccctcacagctgattctcgtggcccagagcacctgcta
aatctagagcaagacacatcagaaagagcaatattaacttcagagaaaagtagagactat
tctagaagccagaatcctgaaagcctctctgctgacaagtttccagtatctctggatagt
tctaccaataaaaataaagaaccaggaatggaaaggtcttccccttctaaattccagttg
tcggataataggtggtatatgcacagctcaaggagtcttcaggacagaaactgcccatct
caaaaggagcccattaatgttgctgacatggaggagcaacagctggctaagtgtgaggcc
caagatttaatggggtcttttttgccaagacaagatcaagagggaaccccttacctgaaa
tctggaatcagccttttctctcatgaacccgagtctgatccttctgaagacagagcccca
gagccagctcatgttcacagcatgccaccctcagcctctgcactgaaattatcccaattt
cgagtagaagaatctaccaagaatccagctgctgcgcacattactaatactacaggttgt
tgtaacctgagggaagaaagtgtgagcaaagagaagccagaagtgatatcttcaacagaa
agaagcaacaaaagactttctatggtggcatcaggcttgaccccaaaagaacttatgctt
gtgcagaaatttgccagaaaacatcatgtcactttaactaatctaattactgaagagact
actcatgtcattatgaaaacagatcctgagtttgtgtgtgaacggacactgaaatatttc
ctgggaattgcaggaggaaaatgggtagttagctatttttgggtcacccagtctattaaa
gaaagaaagatgctggatgagcatgattttgaagtcagaggagatgttgtcaatggaaga
aaccatcaaggcccaaagcgagcaagagaatcccgggacaagaagatcttcaagggccta
gaaatctgttgctatggaccttttaccaatatgcccacagatcaactagagtggatggtg
cagctgtgtggggcttctgtggtgaaggagccctcatcattcaccccaggccagggtact
cacccagttgtggtcgtacagccggatgcctggacagaggatgctggcttccatgtgatc
gggcagatgtgtgaagcacctgtggtaacccgagagtgggtactggacagtgtggccctc
taccagtgccaggagctggacacctatctggtcccccaggtcgcccagagctgctgctga
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integrated database retrieval system
