Bubalus kerabau (carabao): 129651287
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Entry
129651287 CDS
T11435
Symbol
MDM2
Name
(RefSeq) E3 ubiquitin-protein ligase Mdm2 isoform X1
KO
K06643
E3 ubiquitin-protein ligase Mdm2 [EC:
2.3.2.27
]
Organism
bke Bubalus kerabau (carabao)
Pathway
bke01522
Endocrine resistance
bke01524
Platinum drug resistance
bke04068
FoxO signaling pathway
bke04110
Cell cycle
bke04115
p53 signaling pathway
bke04120
Ubiquitin mediated proteolysis
bke04144
Endocytosis
bke04151
PI3K-Akt signaling pathway
bke04218
Cellular senescence
bke04625
C-type lectin receptor signaling pathway
bke04919
Thyroid hormone signaling pathway
bke05163
Human cytomegalovirus infection
bke05165
Human papillomavirus infection
bke05169
Epstein-Barr virus infection
bke05200
Pathways in cancer
bke05202
Transcriptional misregulation in cancer
bke05203
Viral carcinogenesis
bke05205
Proteoglycans in cancer
bke05206
MicroRNAs in cancer
bke05214
Glioma
bke05215
Prostate cancer
bke05218
Melanoma
bke05219
Bladder cancer
bke05220
Chronic myeloid leukemia
Brite
KEGG Orthology (KO) [BR:
bke00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
129651287 (MDM2)
09130 Environmental Information Processing
09132 Signal transduction
04068 FoxO signaling pathway
129651287 (MDM2)
04151 PI3K-Akt signaling pathway
129651287 (MDM2)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
129651287 (MDM2)
09143 Cell growth and death
04110 Cell cycle
129651287 (MDM2)
04115 p53 signaling pathway
129651287 (MDM2)
04218 Cellular senescence
129651287 (MDM2)
09150 Organismal Systems
09151 Immune system
04625 C-type lectin receptor signaling pathway
129651287 (MDM2)
09152 Endocrine system
04919 Thyroid hormone signaling pathway
129651287 (MDM2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
129651287 (MDM2)
05202 Transcriptional misregulation in cancer
129651287 (MDM2)
05206 MicroRNAs in cancer
129651287 (MDM2)
05205 Proteoglycans in cancer
129651287 (MDM2)
05203 Viral carcinogenesis
129651287 (MDM2)
09162 Cancer: specific types
05214 Glioma
129651287 (MDM2)
05220 Chronic myeloid leukemia
129651287 (MDM2)
05218 Melanoma
129651287 (MDM2)
05219 Bladder cancer
129651287 (MDM2)
05215 Prostate cancer
129651287 (MDM2)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
129651287 (MDM2)
05169 Epstein-Barr virus infection
129651287 (MDM2)
05165 Human papillomavirus infection
129651287 (MDM2)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
129651287 (MDM2)
01522 Endocrine resistance
129651287 (MDM2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
bke04131
]
129651287 (MDM2)
04121 Ubiquitin system [BR:
bke04121
]
129651287 (MDM2)
Enzymes [BR:
bke01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.27 RING-type E3 ubiquitin transferase
129651287 (MDM2)
Membrane trafficking [BR:
bke04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
129651287 (MDM2)
Ubiquitin system [BR:
bke04121
]
Ubiquitin ligases (E3)
Single Ring-finger type E3
MDM2/MDM4 proteins
129651287 (MDM2)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
zf-C3HC4_3
Zn_ribbon_RanBP
SWIB
zf-RING_2
SWIB_eIF2D
zf-FPG_IleRS
Motif
Other DBs
NCBI-GeneID:
129651287
NCBI-ProteinID:
XP_055435976
LinkDB
All DBs
Position
1
Genome browser
AA seq
491 aa
AA seq
DB search
MCNTNMSVSTDGAVSTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVIFYLGQY
IMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVSQQEPSDSGT
SMSENRCHLEGGSNQKDLVQELQEEKPSSSDMVSRPSTSSRRRAVSETEENSDELPGERQ
RKRHKSDNISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGVSEHSGDWLDQDS
VSDQFSVEFEVESLDSEDYSLSEEGQELSDEDDEVYRVTVYQAGESDTDSFEEDPEISLA
DYWKCTSCSEMNPPLPPHCNRCWALRENWLPEDKGKDKGNMSEKAKLGDSMQEDEGFDVP
DCKKSTVSDSRESCVEENDDKITQASLSQESEDYSQPSTSNSIIYSSQEDVKEFEREETQ
DKEESMESSFPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCAKKLKKRNKPCPVCRQ
PIQMIVLTYFP
NT seq
1476 nt
NT seq
+upstream
nt +downstream
nt
atgtgcaataccaacatgtctgtgtctactgatggtgctgtaagcacctcacagattcca
gcttcggaacaagagaccctggttagaccaaagccattgcttttgaagttgttgaagtct
gttggtgcacagaaggacacttatactatgaaagaggttatattttatcttggccagtat
atcatgactaaacgattatatgatgaaaaacaacaacatattgtgtattgttcaaatgat
cttctaggagatttgtttggagtcccaagcttctctgtgaaggaacacaggaaaatatat
acaatgatctacagaaatttggtagtagtcagtcagcaagaaccatcagattcaggcaca
tctatgagtgaaaacaggtgtcaccttgaaggtgggagtaatcaaaaggaccttgtgcaa
gagctacaggaagagaaaccttcatcttcagatatggtttctagaccatctacctcatct
agaaggagagcagttagtgagacagaagaaaattcagatgaattacctggtgaacgacag
agaaagcgccacaaatctgataatatttccctttcctttgatgaaagccttgctctgtgt
gtaataagggagatatgttgtgaaagaagcagtagcagtgaatcaacaggaactccatca
aatccggatctggatgctggtgtaagtgaacattcaggtgattggttggatcaggattca
gtttcagatcaattcagtgtagaatttgaagttgagtctcttgattcagaagattatagc
ctcagcgaagaaggacaagaactctcggatgaagatgatgaggtatatcgagttactgtg
tatcaggcaggcgagagtgatacagattcatttgaagaagatcctgaaatttccttagct
gactattggaagtgtacttcatgcagtgaaatgaatcctcccctcccacctcactgcaac
agatgttgggcccttcgtgaaaattggcttcctgaagataaaggaaaagataaagggaat
atgtctgagaaagccaaactaggagactcgatgcaagaagacgagggctttgatgtccct
gactgtaagaaatctacagtcagtgattccagagaatcatgtgttgaagaaaatgatgat
aaaatcacacaagcctctctatctcaagaaagtgaggactattctcagccatcgacttct
aatagcatcatttatagtagccaagaagatgtcaaagagtttgagagagaagaaacacaa
gacaaagaagaaagtatggagtctagttttccccttaatgccattgaaccttgtgtgatt
tgccagggtcgacctaaaaatggttgcattgtccatggcaaaacaggacatcttatggca
tgctttacatgtgcaaagaagttaaaaaaaaggaataagccctgtccagtatgtaggcaa
ccaattcaaatgattgtgctaacttatttcccctag
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