KEGG   Burkholderia mallei NCTC 10247: BMA10247_3219
Entry
BMA10247_3219     CDS       T00479                                 
Symbol
metH
Name
(GenBank) methionine synthase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
bmn  Burkholderia mallei NCTC 10247
Pathway
bmn00270  Cysteine and methionine metabolism
bmn00450  Selenocompound metabolism
bmn00670  One carbon pool by folate
bmn01100  Metabolic pathways
bmn01110  Biosynthesis of secondary metabolites
bmn01230  Biosynthesis of amino acids
bmn04980  Cobalamin transport and metabolism
bmn04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:bmn00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    BMA10247_3219 (metH)
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    BMA10247_3219 (metH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    BMA10247_3219 (metH)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    BMA10247_3219 (metH)
   04980 Cobalamin transport and metabolism
    BMA10247_3219 (metH)
Enzymes [BR:bmn01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     BMA10247_3219 (metH)
SSDB
Motif
Pfam: Met_synt_B12 Pterin_bind B12-binding_2 B12-binding
Other DBs
NCBI-ProteinID: ABO05072
LinkDB
Position
I:3179959..3182676
AA seq 905 aa
MTDHTMRLAGLEPFNVTSGTLFINVGERTNVTGSKAFARMILNGQFDEALAVARQQVENG
AQVIDVNMDEAMLDSKAAMVRFLNLIASEPDIARVPIMIDSSKWDVIEAGLKCVQGKAIV
NSISLKEGKEAFVHHAKLIRRYGAAAVVMAFDEAGQADTLARKTEICKRSYDVLVNEVGF
APEDIVFDPNIFAVATGIDEHNNYAVDFIEATRWIKRNLPYAKVSGGVSNVSFSFRGNDP
VREAIHTVFLYHAIQAGMDMGIVNAGQLGVYAELDAELRERVEDVILNRRDDSTDRLLEI
ADKFKTGAAKKEENLEWRSQPVEKRLAHALVHGITNFIVEDTEEARAKIAAAGGRPINVI
EGPLMDGMNIVGDLFGQGKMFLPQVVKSARVMKQAVAHLIPFIEEEKRLLAQAGGDVRAK
GKIVIATVKGDVHDIGKNIVSVVLQCNNFEVVNMGVMVPCNEILAKAKVEGADIVGLSGL
ITPSLEEMAYVASEMQRDDYFRVKKIPLLIGGATTSRVHTAVKIAPHYEGPVVYVPDASR
SVSVASNLLSDEGATKYLDELKADYERIRAQHANKKALPLVTLAEARANKTKIDWARYTS
VKPKFIGRRMFKNYDLNELANYIDWGPFFQTWDLAGPYPAILNDEIVGESARRVFSDAKS
MLARLIQGRWLTANGVIALLPANTVGDDDIEIYTDDTRAEVLLTWHNLRQQSVRPVVDGV
MRPNRSLADFIAPKDSGVADYIGMFAVTAGIGVDAKEKQFLADHDDYSAIMLKALADRLA
EAFAEAMHARVRRELWGYAATEQLDNDALIAEQYAGIRPAPGYPACPDHLVKRAMFEALH
TDEIGMSVTDSLAMLPAASVSGFYLAHPDSTYFSVGKIGQDQLEDFARRTALSKADAERA
LAPLL
NT seq 2718 nt   +upstreamnt  +downstreamnt
atgaccgaccacacgatgcgcctagccggcctcgagccgttcaacgtcacgtccgggacg
ctcttcatcaacgtcggcgaacgcaccaacgtcaccggctcgaaggcgttcgcgcgcatg
atcctcaacggccagttcgacgaggcgctcgcggtcgcgcgccagcaggtcgagaacggc
gcgcaggtgatcgacgtcaacatggacgaggcgatgctcgattcgaaggcggcgatggtg
cgcttcctgaacctgatcgcatccgagccggacatcgcgcgcgtgccgatcatgatcgat
tcgtcgaagtgggacgtgatcgaggcgggcctgaagtgcgtgcagggcaaggcgatcgtc
aactcgatctcgctgaaggaaggcaaggaagcgttcgtgcatcacgcgaagctgatccgc
cgctacggcgccgcggccgtcgtgatggcgttcgacgaagcgggccaggccgacacgctc
gcacgcaagaccgagatctgcaagcgctcgtacgacgtgctcgtgaacgaagtcggcttc
gcgcccgaggacatcgtcttcgatccgaacatcttcgcggtggcgacgggcatcgacgag
cacaacaactacgcggtcgacttcatcgaggcgacccgctggatcaagcgcaacctgccg
tacgcgaaggtgagcggcggcgtgtcgaacgtgtcgttctcgtttcgcggcaacgatccc
gtgcgcgaggcgatccacaccgtgttcctctatcacgcgatccaggcggggatggacatg
ggcatcgtcaacgcgggccagctcggcgtgtacgcggagctcgacgccgagctgcgcgaa
cgcgtcgaggacgtgatcctcaaccgccgcgacgattcgaccgaccggctgctcgagatc
gccgacaagttcaagaccggtgccgcgaaaaaggaagagaacctcgaatggcgcagccag
ccggtcgagaagcggctcgcgcacgcgctcgtgcacggcatcacgaacttcatcgtcgag
gataccgaagaagcgcgcgcgaagatcgccgcggcgggcgggcgcccgatcaacgtgatc
gaaggcccgctgatggacgggatgaacatcgtcggcgacctgttcggccagggcaagatg
ttcctgccgcaggtggtgaaatccgcgcgcgtgatgaaacaggccgtcgcgcacctgatc
ccgttcatcgaggaagagaagcgtctgctcgcgcaagcgggcggcgacgtgcgcgcgaag
ggcaagatcgtcatcgcgaccgtgaagggcgacgtgcacgacatcggcaagaacatcgtg
tcggtcgtgcttcagtgcaacaacttcgaagtggtcaacatgggcgtgatggtgccgtgc
aacgagatcctcgcgaaggcgaaggtcgagggcgcggacatcgtcgggctgtccggcctc
atcacgccgagcctcgaggaaatggcgtacgtcgcctccgagatgcagcgcgacgactac
ttccgcgtgaagaagattccgctgctgatcggcggcgcgacgacctcgcgcgtgcacacg
gccgtgaagatcgcgccgcactacgagggcccggtcgtctacgtgccggacgcgtcgcgc
tcggtatcggtcgcctcgaacctgctgtccgacgaaggcgcgacgaaatacctcgacgag
ctgaaagccgactacgagcgcatccgcgcgcagcacgcgaacaagaaggcgctgccgctc
gtcacgctcgccgaagcgcgcgcgaacaagacgaagatcgactgggcgcgctacacgagc
gtcaagccgaagttcatcggccggcgcatgttcaagaactacgatctgaacgagctcgcg
aactacatcgactggggcccgttcttccagacctgggacctcgcgggcccgtacccggcg
atcctgaacgacgagatcgtcggcgaatcggcgcgccgcgtattctccgacgcgaaatcg
atgctcgcgcgcctcatccagggccgctggctcaccgcgaacggcgtgatcgcgctgttg
ccggcgaacacggtgggcgacgacgacatcgagatctacaccgacgacacgcgcgccgaa
gtgctgctcacgtggcacaacctgcgccagcagagcgtgcgcccggtggtggacggcgtg
atgcggccgaaccgctcgctcgccgatttcatcgcgccgaaggattcgggcgtcgccgac
tacatcgggatgttcgcggtgacggccggcatcggcgtcgacgcgaaggaaaaacagttc
ctcgccgatcacgacgactacagcgcgatcatgctcaaggcgctcgccgaccggctcgcg
gaggcgttcgccgaggcaatgcacgcgcgtgtgcgccgcgagctgtggggctacgcggcg
accgagcagctcgacaacgacgcgctgatcgccgagcagtacgcgggcatccgcccggcg
cccggttacccggcgtgcccggaccacctcgtgaaacgcgcaatgttcgaagcgcttcat
acagacgagatcgggatgagcgtcaccgattcgctcgcgatgctgccggccgcgagcgtc
tccggcttctatctcgcgcatccggacagcacgtacttctcggtcggcaagatcggccag
gatcagctcgaggatttcgcgcgccgcacggcgctgtcgaaggcggacgccgagcgcgcg
ctcgcgccgctgctctga

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