Balaenoptera musculus (blue whale): 118883967 Help Entry 118883967         CDS       T09887                                  Symbol IRS2 Name (RefSeq) insulin receptor substrate 2   KO K07187   insulin receptor substrate 2 Organism bmus  Balaenoptera musculus (blue whale) Pathway bmus04022   cGMP-PKG signaling pathway bmus04068   FoxO signaling pathway bmus04081   Hormone signaling bmus04140   Autophagy - animal bmus04152   AMPK signaling pathway bmus04211   Longevity regulating pathway bmus04213   Longevity regulating pathway - multiple species bmus04910   Insulin signaling pathway bmus04920   Adipocytokine signaling pathway bmus04923   Regulation of lipolysis in adipocytes bmus04930   Type II diabetes mellitus bmus04931   Insulin resistance bmus04932   Non-alcoholic fatty liver disease bmus04935   Growth hormone synthesis, secretion and action bmus05010   Alzheimer disease bmus05206   MicroRNAs in cancer Brite KEGG Orthology (KO) [BR:bmus00001]  09130 Environmental Information Processing   09132 Signal transduction    04068 FoxO signaling pathway     118883967 (IRS2)    04022 cGMP-PKG signaling pathway     118883967 (IRS2)    04152 AMPK signaling pathway     118883967 (IRS2)   09133 Signaling molecules and interaction    04081 Hormone signaling     118883967 (IRS2)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     118883967 (IRS2)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     118883967 (IRS2)    04923 Regulation of lipolysis in adipocytes     118883967 (IRS2)    04920 Adipocytokine signaling pathway     118883967 (IRS2)    04935 Growth hormone synthesis, secretion and action     118883967 (IRS2)   09149 Aging    04211 Longevity regulating pathway     118883967 (IRS2)    04213 Longevity regulating pathway - multiple species     118883967 (IRS2)  09160 Human Diseases   09161 Cancer: overview    05206 MicroRNAs in cancer     118883967 (IRS2)   09164 Neurodegenerative disease    05010 Alzheimer disease     118883967 (IRS2)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     118883967 (IRS2)    04932 Non-alcoholic fatty liver disease     118883967 (IRS2)    04931 Insulin resistance     118883967 (IRS2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  IRS PH PH_11 MEKK4_N Motif Other DBs NCBI-GeneID:  118883967 NCBI-ProteinID:  XP_036687029 UniProt:  A0A8B8VQ59 LinkDB All DBs Position 18:complement(76695958..76725282) Genome browser AA seq 1349 aa AA seqDB search MASPPMHGRPRPAGGDGPNLNLNHNNNNNNSGVRKCGYLRKQKHGHKRFFVLRGPGAGGD EAAAATAGGGPAPQPPRLEYYESEKKWRSKAGAPKRVIALDCCLNINKRADAKHKYLIAL YTKDEYFAVAAENEQEQEGWYRALTDLVSEGRASAGDAPPAAAAAPSASCSASLPGALGG SAGAAAAAAADDSYGLVAPATAAYREVWQVNLKPKGLGQSKNLTGVYRLCLSARTIGFVK LNCEQPSVTLQLMNIRRCGHSDSFFFIEVGRSAVTGPGELWMQADDSVVAQNIHETILEA MKALKELFEFRPRSKSQSSGSSATHPISVPGARRHHHLVNLPPSQTGLVRRSRTDSLAAT PPAAKCSSCRVRTASEGDGGVAAGAGAAGGRPVSVAGSPLSPGPVRAPLSRSHTLSGGCG GRASKVTLAPAGGALQHSRSMSMPVAHSPPAAATSPGSLSSSSGHGSGSYPPPPGPHPHM QHPLHPQRPSSGSASASGSPSDPGFMSLDEYGSSPGDLRAFCSLRSNTPESIAETPPARD GSAGELYGYMTMDRPLSHCGRPYRRVSGDGAQDLDRGLRKRTYSLTTPARQRPVPQPSSA SLDECTLMRATFSGSSGRLCPSCPASSPKVAYHPYPEDYGDIEIGSHRSSSSNLGTDDGY MPMTPGVALTGGGGGSCKSDDYMPMSPTSVSAPKQILQPRAAAAALPPAGAAGPTPASAA GRAFPGSGGGYKTSSPAESSPEDSGYMRMWCGGSKLAVESAADGRLLPNGDYLNMSPGDA GASGTPPDFFSAALHGGGGGGGEMLRGVPGYCYSSLPRSYKAPYACNGDGDQYVLMSSPV GRILEEERLESTAGPGSTQPAGAFAAGAGGGGGHPQPPHAAVPSPARPGGGGSGRPEGFL GQRCRAARPTRLSLEGLQTLPRMHEYPLPPEPKSPGEYINIDFGEAGARLSPPAPPLLAS AASSSSLLSAGSPASSLGSGTPGTSGDSRQRSPLSDYMNLDFSSPKSPQPGGQAGDPVGS LDALLSPEASAYPPLPPRPAAPSSALQPPPPPPPPPGELYRLPPAPPSQGPGAASSPSSG AGDSGDYTEMAFGVAATPPQPIAAPPKPDGARVSSLVSGLKRLSLMDQVSGVEAFLQASQ PPDPHRGAKVIRADPQGGRRRHSSETFSSTTTVTPVSPSFAHNPKRHNSASVENVSLRKS GEGGGGSVLGGGDEPPTSPRQLPPPLPPQARPWTPSQPGGLVGCPGGSGSPMRRETSAGF QNGLNYIAIDVRDEPGLLPPPQPPQHPQMGDKSAWGRTRSLGGLIGAVGAGSTGGVCVGP GPGALPSASTYASLDFLTHHLKEATVVKE NT seq 4050 nt NT seq  +upstreamnt  +downstreamnt atggcgagcccgccgatgcacgggcgccccaggccggcgggcggcgacggccccaacctc aacctcaaccacaataacaacaacaacaacagcggcgtgcgcaagtgcggctacctgcgc aagcagaagcacggccacaagcgcttcttcgtgctgcgcggacccggcgcgggcggcgac gaggcggcggcggcgacagcgggcggggggccggcgccgcagccgccgcggctcgagtac tacgagagcgagaagaagtggcggagcaaagcgggcgccccgaagcgggtcatcgcgctc gactgctgcctgaacatcaacaagcgcgccgacgccaagcacaagtacctgatcgccctc tacaccaaggacgagtactttgcagtggcggccgagaacgagcaggagcaggagggctgg taccgcgcgctcaccgacctggtcagcgagggccgagcgagcgccggcgacgcgcccccc gccgccgccgccgccccctccgcgtcctgcagcgcctccctgcccggcgccctgggcggc tcggccggcgccgccgccgccgccgcggccgatgacagctacgggctggtggcgcctgcc acggccgcctaccgtgaggtgtggcaggtgaacctgaagcccaagggcctgggccagagc aagaacctgacgggcgtgtaccgcctgtgcctgtcggcgcgcaccatcggcttcgtgaag ctcaactgcgagcagccgtcggtgacgctgcagctcatgaacatccgccgctgcggccac tcggacagcttcttcttcatcgaggtgggccgctcggccgtcacgggccccggtgagctg tggatgcaggcagacgactcggtggtggcgcagaacatccacgagaccatcctggaggcc atgaaggcgctcaaggagctcttcgagttccggccgcgcagcaagagccagtcgtccggc tcgtcggccacgcaccccatcagcgtccccggcgcgcgtcgccaccaccacctggtcaat ctgccccccagccagacgggcctggtgcgccgctcgcgcaccgacagcttggccgccaca ccgccggccgccaagtgcagctcgtgccgggtgcgcacggccagcgagggcgacggcggc gtggcggcgggggccggggcggcgggcggcaggccggtgtcggtggcggggagccccctg agcccggggccggtgcgcgcgcccctgagccgctcgcacaccctgagcggcggctgcggc ggccgcgctagcaaggtgacgctggcgccggcagggggcgccctgcagcacagccgctcc atgtccatgcccgtggcgcactcgcccccggcggccgccaccagccccggcagcctgtcg tccagcagcgggcacggctcgggctcctacccgccgcccccgggcccgcacccgcacatg cagcaccccctgcacccccagcgaccctccagcggcagcgcctcggcctcgggctccccc agcgaccctggtttcatgtccctggacgagtacggctcgagccctggggacctgagagcc ttctgcagtctcaggagcaacacgcccgagtccatcgccgagacgcccccggccagggac ggcagcgcgggcgagctgtacgggtacatgaccatggaccggcccctgagccactgcggc cgaccctaccgcagagtctccggggacggggcccaggacttggacaggggcctgaggaag aggacctactccctgaccacgcctgcccggcagcggccagtgccccagccctcctcggcg tccctggatgagtgcaccctgatgcgggccaccttctccggcagctcaggccgcctctgc ccgtcgtgccccgcgtcctcccccaaagtggcctaccacccctaccccgaggactacggc gacatcgagatcgggtcgcacaggagctccagcagtaacctgggcacggacgacggctac atgcccatgacccccggcgtggccctcacgggcggcggcggcgggagctgcaagagcgac gactacatgcccatgagccccaccagcgtgtccgccccgaagcagatcctgcagccgcgc gccgccgccgcggccttgccccccgcgggagccgcggggcccacgcccgcgtcggccgcc ggcagggccttcccggggagcgggggcggctacaagaccagctccccggccgagagctcc cccgaggacagcggctacatgcgcatgtggtgcggcggctccaagctggcggtggagagc gccgccgacggcaggctgcttccaaacggggactacctcaacatgtcccccggcgacgcg ggcgcctcgggcaccccgcccgacttcttctcggccgccctgcacggcggcggcggcggc ggcggggagatgctccggggcgtccccggctactgctacagctccctgccccgctcctac aaggccccctacgcctgcaacggggacggcgaccagtacgtgctcatgagctcccccgtg gggcgcatcctggaggaggagcggctggagtcgacggccggcccggggtccacgcagcca gccggcgccttcgcggccggggccggaggcggcggcggccacccgcagccaccccacgcg gcggtgccttcgcccgcgaggcccggcggcggtggcagcggccgcccggagggcttcctg ggccagcgctgccgggccgcgcggcccacgcgcctgtccctggaggggctgcagaccctg ccgcgcatgcacgagtacccgctgccgcccgagcccaagagcccgggcgagtacatcaac atcgacttcggcgaggcgggcgcgcgcctgtcgccgcccgcgcccccgctgctggcctcg gccgcctcgtcgtcgtcgctgctgtccgccggcagcccggcctcgtcgctgggctcgggc accccgggcaccagcggcgacagccggcagcgctccccgctctccgactacatgaacctc gacttcagctcgcccaagtcaccccagccgggcggccaggccggggaccccgtgggctcc ctggacgccctcctgtcccccgaggcctccgcgtacccgccgctgcccccgcgccccgcc gccccctcctcggccctgcagccgccgccgccgccgccgcccccgcccggagagctgtac cgcctgcctccggcaccgccctcccagggccctggcgcggcctcctctccgtcctcgggg gcgggcgacagcggcgactacaccgagatggccttcggcgtggctgccacgccgccgcaa ccgatcgccgcgcccccgaagcccgacggggcccgcgtgagcagcctcgtgtccggcctg aagaggctgagcctcatggaccaggtgtcgggggtcgaggccttcctgcaggctagccag cccccagacccgcaccgcggcgccaaggtcatccgcgcggacccgcaagggggccgccgc cgccacagctcggagaccttctcctcgaccaccactgtgacccccgtgtccccgtccttc gcccacaaccccaagcgccacaactcggcctcggtggagaatgtgtctctcaggaaaagt ggcgaagggggcggcggcagcgtcctgggtggcggcgacgagccccccacgtccccccgc cagttgccgccgccgctccccccgcaggcgcggccctggacgccgagccagcccgggggt ttggtcggctgccccgggggcagtggctcgccgatgcgccgggagacctctgccggcttc cagaacggcctcaactacatcgccatcgacgtgagggacgagccggggctgttgccgccc ccgcagccgccgcagcatcctcagatgggagacaagagcgcctggggccggacccggagc ctcgggggtctcatcggcgcggtaggggccggcagcaccggcggcgtgtgtgtggggccc ggccctggcgccctgccctccgccagcacctacgccagcctcgacttcttgacgcatcac ctgaaagaggcgacggtcgtgaaagagtga

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