Balaenoptera musculus (blue whale): 118892062 Help Entry 118892062         CDS       T09887                                  Symbol INSR Name (RefSeq) insulin receptor isoform X1   KO K04527   insulin receptor [EC:2.7.10.1] Organism bmus  Balaenoptera musculus (blue whale) Pathway bmus04010   MAPK signaling pathway bmus04014   Ras signaling pathway bmus04015   Rap1 signaling pathway bmus04022   cGMP-PKG signaling pathway bmus04066   HIF-1 signaling pathway bmus04068   FoxO signaling pathway bmus04072   Phospholipase D signaling pathway bmus04081   Hormone signaling bmus04150   mTOR signaling pathway bmus04151   PI3K-Akt signaling pathway bmus04152   AMPK signaling pathway bmus04211   Longevity regulating pathway bmus04213   Longevity regulating pathway - multiple species bmus04520   Adherens junction bmus04910   Insulin signaling pathway bmus04913   Ovarian steroidogenesis bmus04923   Regulation of lipolysis in adipocytes bmus04930   Type II diabetes mellitus bmus04931   Insulin resistance bmus04932   Non-alcoholic fatty liver disease bmus04960   Aldosterone-regulated sodium reabsorption bmus05010   Alzheimer disease bmus05415   Diabetic cardiomyopathy Brite KEGG Orthology (KO) [BR:bmus00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     118892062 (INSR)    04014 Ras signaling pathway     118892062 (INSR)    04015 Rap1 signaling pathway     118892062 (INSR)    04066 HIF-1 signaling pathway     118892062 (INSR)    04068 FoxO signaling pathway     118892062 (INSR)    04072 Phospholipase D signaling pathway     118892062 (INSR)    04022 cGMP-PKG signaling pathway     118892062 (INSR)    04151 PI3K-Akt signaling pathway     118892062 (INSR)    04152 AMPK signaling pathway     118892062 (INSR)    04150 mTOR signaling pathway     118892062 (INSR)   09133 Signaling molecules and interaction    04081 Hormone signaling     118892062 (INSR)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04520 Adherens junction     118892062 (INSR)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     118892062 (INSR)    04923 Regulation of lipolysis in adipocytes     118892062 (INSR)    04913 Ovarian steroidogenesis     118892062 (INSR)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     118892062 (INSR)   09149 Aging    04211 Longevity regulating pathway     118892062 (INSR)    04213 Longevity regulating pathway - multiple species     118892062 (INSR)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     118892062 (INSR)   09166 Cardiovascular disease    05415 Diabetic cardiomyopathy     118892062 (INSR)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     118892062 (INSR)    04932 Non-alcoholic fatty liver disease     118892062 (INSR)    04931 Insulin resistance     118892062 (INSR)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:bmus01001]     118892062 (INSR)   09183 Protein families: signaling and cellular processes    04090 CD molecules [BR:bmus04090]     118892062 (INSR) Enzymes [BR:bmus01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.1  receptor protein-tyrosine kinase      118892062 (INSR) Protein kinases [BR:bmus01001]  Receptor tyrosine kinases (RTK)   INSR family [OT]    118892062 (INSR) CD molecules [BR:bmus04090]  Proteins   118892062 (INSR) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK_Tyr_Ser-Thr Recep_L_domain Pkinase Furin-like Insulin_TMD fn3 Ig_DSCAM-DSCAML_C Kinase-like B2 DUF4476 Motif Other DBs NCBI-GeneID:  118892062 NCBI-ProteinID:  XP_036702012 UniProt:  A0A8C0CAA7 LinkDB All DBs Position 3:165841189..165974108 Genome browser AA seq 1382 aa AA seqDB search MGAGGGRGAAAVPLLVAVAALLLGAAGHLYPGEVCPGMDIRNNLTRLHELANCSVIEGHL QILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYAL VIFEMVHLKELGLYNLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNYIVLNKDDNE ECGDICPGTAKGKTNCPATVINGQFVERCWTHSHCQKVCPTICKSHGCTAEGLCCHSECL GNCSEPDDPTKCVACRNFYLDGRCVETCPPPYYHFQDWRCVNFSFCQDLHNKCKNSRRQG CHQYVIHNNKCIPECPSGYTMNSSNLMCTPCLGPCPKVCHLLEGEKTIDSVTSAQELRGC TIINGSLIINIRGGNNLAAELEANLGLIEEISGYLKIRRSYALVSLSFFRKLRLIRGETL EIGNYSFYALDNQNLRQLWDWSKHNLTITQGKLFFHYNPKLCLSEIHKMEEVSGTKGRQE RNDIALKTNGDQASCENELLKFSYIRTSYDKILLKWEPYWPPDFRDLLGFMLFYKEAPYQ NVTEFDGQDACGSNSWTVVDIDPPMRSNDPKSQNHPGWLMRGLKPWTQYAIFVKTLVTFS DERRTYGAKSDIIYVQTDATNPSVPLDPISVSNSSSQIILKWKPPSDPNGNITHYLVFWE RQEEDGELYELDYCLKGLKLPSRTWSPPFESEGSQKHNQSEYEDSAGECCSCPKTDSQIL KELEESSFRKTFEDYLHNVVFIPRKSSSGPVAEDTRPSRKRRALGDVGNVTAAVPTIPGF PNTSSTSAPTSSEEHRPFEKVVNKESLVISGLRHFTGYRIELQACNQDSPEERCSVAAYV SARTMPEAKADDIVGPVTHEIFENNVVHLMWQEPKEPNGLIVLYEVSYRRYGEEELHLCV SRKHFALERGCRLRGLPPGNYSVRVRATSLAGNGSWTEATYFYVTDYLDVPSNIAKIIIG PLIFVFLFSVVIGSIYLFLRKRQPDGPLGPLYASSNPEYLSASDVFPCSVYVPDEWEVPR EKITLLRELGQGSFGMVYEGNARDIVKGEAETRVAVKTVNESASLRERIEFLNEASVMKG FTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSYLRSLRPEAENNPGRPPPTLQEMIQMA AEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETDYYRKGGKGLLPV RWMAPESLKDGVFTTSSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDQPDN CPERVTDLMRMCWQFNPKMRPTFLEIVDLLKDELHPSFPEVSFFHSEENKVPESEELEME FEDMESVPLDRSSHAQREEAGGRDGGSALGLKRNYEEHIPYTHMNGGKKNGRILTLPRSN PS NT seq 4149 nt NT seq  +upstreamnt  +downstreamnt atgggcgccgggggcgggcggggggcggcggccgtgccgctgctggtggccgttgccgcg ctgctgctgggcgccgcgggccacctgtaccctggagaggtgtgccccggcatggatatc cggaataacctcacccggctgcacgagctggccaactgctcggtcatcgaaggacatttg cagatcctattgatgttcaaaacgagacctgaggacttccgagacctcagtttccccaag ctcatcatgatcactgattacttgctgctcttccgggtctacgggctggagagcctgaag gacctgttccccaacctcacggtcatccggggctcccgcctcttctttaactacgcgctg gtcatcttcgagatggttcacctgaaggagcttggcctctacaacttgatgaacatcacc cggggctccgtccgcatcgagaagaacaatgaactctgctacctggccactatcgactgg tctcgcatcctggattccgtggaggataattacatcgtgctgaacaaagacgacaatgag gagtgtggggacatttgtccaggcaccgcgaagggcaagaccaactgccctgccaccgtc atcaacgggcaatttgtggagcggtgttggacgcacagccactgccagaaagtgtgtccg accatctgtaagtctcacggctgcaccgctgagggtctctgttgccacagtgagtgcttg ggcaactgctctgagcctgacgaccccaccaagtgtgtggcctgtcgaaacttctacctg gatggcaggtgcgtggagacctgcccgcccccctactaccacttccaagactggcgctgt gtgaacttcagcttctgccaggatttgcacaacaaatgcaagaactctcggaggcagggc tgccaccagtatgtcattcacaataacaagtgcatccctgagtgcccctccgggtacaca atgaattccagcaacttgatgtgcactccatgcctgggcccctgtcccaaggtgtgccac ctcctggaaggcgagaagaccattgactcagtgacatctgcccaggagctccgaggctgc accatcatcaacggaagcttaatcatcaacattcgagggggcaacaacctggcagctgag ctagaggccaaccttggactcattgaagaaatttcagggtatctgaaaatccgccgatca tatgccctcgtgtcactttccttcttccggaagttacgtctgattcgaggggagaccttg gaaatcgggaactactctttctatgccttggacaaccagaacctaaggcagctgtgggac tggagcaaacacaacctcaccatcactcaggggaaactcttcttccactataatcccaaa ctctgcttgtcagaaattcacaagatggaggaagtttccggaaccaaggggcgccaggag agaaacgacattgccctgaagaccaatggggaccaggcgtcctgcgaaaatgaattactt aaattttcttacattcggacatcttatgacaagatcttgctgaaatgggagccatattgg ccccccgacttccgagacctcctgggattcatgctcttctacaaagaggccccttatcag aacgtgacggagtttgatgggcaggacgcatgtggctccaacagctggaccgtggtggat attgacccgcctatgaggtccaacgaccccaagtcacagaaccaccccgggtggctaatg cgtggtctcaagccctggacccagtatgccatctttgtcaagaccttggtcaccttttct gatgaacgccgcacatacggggccaagagcgacatcatctatgtccagacagatgccact aatccttctgtccccctggatcccatctcggtgtctaattcttcgtcccagattattctg aagtggaagcctccctctgaccccaatggcaacatcacacactacttggtattctgggag agacaggaggaagatggtgaactgtatgaattagattattgcctcaaagggttgaagctg ccctcccggacctggtctccaccgttcgagtctgaggggtcccagaagcacaatcagagt gagtacgaagactctgccggtgaatgctgttcctgcccgaagaccgactctcagatcctc aaggagctggaggagtcctcgttccggaaaacgttcgaagattacctgcacaacgtggtt ttcatccccagaaaatcctcttcaggccctgttgccgaggacactaggccgtcgaggaaa cgcagggcccttggtgatgtggggaatgtgacagcggccgtgcccaccattccgggattc cccaatacgtcctcaaccagcgcacctacgagctcagaggagcacagaccgttcgagaaa gtggtgaacaaggagtctctggtcatctctggcctgcgtcactttactggctatcgcatt gagctgcaggcttgcaaccaagattcccccgaggagaggtgcagtgtggctgcatatgtc agtgccaggaccatgcccgaagccaaggcagatgatattgttggccccgtgacccacgaa atcttcgagaacaacgtcgttcacttgatgtggcaggagcccaaggaacccaacggtctg atcgtgctgtacgaagtgagttatcgacgatacggcgaagaggagctgcacctctgcgtc tcccgcaagcattttgctctggagcggggctgcaggctgcgtggtctgccacccgggaat tacagtgtgcgagttcgggccacctccctggcgggcaatggctcctggacggaagccacc tatttctacgtcacagactatttagacgtgccatcaaatattgcaaaaattatcatcggc cccctcatctttgtctttctcttcagtgttgtgatcggaagtatttatctattcctgaga aagaggcagccggatgggccactgggaccactgtatgcttcttcaaaccccgagtacctc agtgccagcgatgtgtttccctgctctgtgtacgtgccggatgagtgggaggtgcctcga gagaagatcacgctcctgcgagaactggggcagggctccttcggcatggtgtacgagggc aacgccagggacattgtcaagggcgaggcggagacccgagtggcggtgaagacggtcaac gagtccgccagcctgcgagagcggatcgaatttctcaacgaggcctcggtcatgaagggc ttcacctgccaccacgtggtccgcctcctgggggtggtatccaaaggccagccgacgctg gtggtgatggagttgatggctcacggggacttgaagagctacctccgttccctgcggcct gaggccgagaataaccccggccgccctccccctaccctgcaagagatgattcagatggct gcggagatcgccgacgggatggcatacctgaacgccaagaagtttgtacaccgggacctc gcagctcgaaactgtatggtcgcccacgattttaccgtcaaaattggagactttggaatg accagagacatctacgaaacggattactaccggaaagggggaaagggtctgctccccgtg cggtggatggcacccgaatccctgaaggacggggtctttaccacttcttcggacatgtgg tcctttggcgtggtcctttgggaaattaccagcttggcggaacagccttaccaaggccta tcaaacgagcaggtgttaaaatttgtcatggatggagggtatctggatcaacccgacaac tgtccagagagagtcaccgacctgatgcgcatgtgctggcagttcaaccccaagatgcgg ccgaccttcctggagattgtcgacctgctcaaggacgagctgcaccccagtttccccgaa gtttccttcttccacagcgaggagaacaaggtgcccgagagcgaggagctggagatggaa tttgaggacatggagagtgtccccctggaccggtcgtcacatgcgcagagggaggaggcc gggggccgggatggagggtccgcgctggggctaaagagaaactatgaggagcacatcccc tacacccacatgaacgggggcaagaaaaacggacgcattctgactctgccccggtctaat ccttcctaa

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