KEGG   Balaenoptera musculus (blue whale): 118895440
Entry
118895440         CDS       T09887                                 
Symbol
FGFR3
Name
(RefSeq) fibroblast growth factor receptor 3 isoform X1
  KO
K05094  fibroblast growth factor receptor 3 [EC:2.7.10.1]
Organism
bmus  Balaenoptera musculus (blue whale)
Pathway
bmus01521  EGFR tyrosine kinase inhibitor resistance
bmus04010  MAPK signaling pathway
bmus04014  Ras signaling pathway
bmus04015  Rap1 signaling pathway
bmus04020  Calcium signaling pathway
bmus04144  Endocytosis
bmus04151  PI3K-Akt signaling pathway
bmus04550  Signaling pathways regulating pluripotency of stem cells
bmus04810  Regulation of actin cytoskeleton
bmus05200  Pathways in cancer
bmus05206  MicroRNAs in cancer
bmus05219  Bladder cancer
bmus05230  Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:bmus00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    118895440 (FGFR3)
   04014 Ras signaling pathway
    118895440 (FGFR3)
   04015 Rap1 signaling pathway
    118895440 (FGFR3)
   04020 Calcium signaling pathway
    118895440 (FGFR3)
   04151 PI3K-Akt signaling pathway
    118895440 (FGFR3)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    118895440 (FGFR3)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    118895440 (FGFR3)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    118895440 (FGFR3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    118895440 (FGFR3)
   05206 MicroRNAs in cancer
    118895440 (FGFR3)
   05230 Central carbon metabolism in cancer
    118895440 (FGFR3)
  09162 Cancer: specific types
   05219 Bladder cancer
    118895440 (FGFR3)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    118895440 (FGFR3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:bmus01001]
    118895440 (FGFR3)
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:bmus04090]
    118895440 (FGFR3)
Enzymes [BR:bmus01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     118895440 (FGFR3)
Protein kinases [BR:bmus01001]
 Receptor tyrosine kinases (RTK)
  FGFR family [OT]
   118895440 (FGFR3)
CD molecules [BR:bmus04090]
 Proteins
  118895440 (FGFR3)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase I-set Ig_3 ig Ig_2 FGFR3_TM V-set C2-set_2 ABC1 Pkinase_fungal
Other DBs
NCBI-GeneID: 118895440
NCBI-ProteinID: XP_036708378
UniProt: A0A8B8XFA1
LinkDB
Position
5:complement(139646295..139661955)
AA seq 835 aa
MGAPACSLAFFVAVAVVMTGAVSGSPGMEQRVVRRAAEVPGPEPGQQELVFGSGDTVELS
CHLPAGAPSGPTVWVKDGVALAPSDRILVGPQRLQVLNASHEDAGAYSCRQRLSQSVLCR
FTVRVTDAPSSGDDEDGEDEAEDTAGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPT
PSISWLKNGKEFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTL
DVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGT
PYVTVLKSWISESAEADVRLRLANVSERDGGEYLCRASNFIGVAEKAFWLRVRGPQAAEE
ELVEAGEAGSVYAGVLSYGVGFLLFILVVAAVTLCRLRSPPKKGLGSPAVHKVSRFPLKR
QQVSLESSSSMSSNTPLVRIARLSSGEGPALANVSELELPADPKWELSRARLTLGKPLGE
GCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIIN
LLGACTQGGPLYVLVEYAAKGNLREYLRARRPPGTDYSFDTCRLPEEQLTFKDLVSCAYQ
VARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKW
MAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCT
HDLYMIMRECWHAVPSQRPTFKQLVEDLDRVLTVTSTDVAGARGREGPRPAGQAPINVRA
DPSLPCCRWCAVTNGSHRPGLKTWNRWTDGQTTSTCVRVHTCVLWGPRRARPAVR
NT seq 2508 nt   +upstreamnt  +downstreamnt
atgggcgccccggcttgctccctcgcgttctttgtggccgtggcagtcgtgatgaccggc
gccgtctccgggtccccgggcatggagcagcgcgtcgtgcggagagcagcagaggtcccg
ggccctgagcctggccagcaggagctggtctttggcagcggggacaccgtggagctgagc
tgccacttgcccgcgggggctccctcagggcccacggtctgggtgaaggacggcgtggcg
ctggcgccctcagaccgcatcctggtggggccgcagcggctgcaggtgctcaacgcctcc
catgaggacgccggggcctacagctgccgccagcgcctctcccagagcgtcctgtgccgc
ttcaccgtgcgcgtgacagacgctccgtcctcgggagacgatgaagatggggaggacgag
gctgaagacacagcaggcgccccttactggacgcggcctgagcggatggataagaagctg
ctggcggtgccggctgccaacacggttcgcttccgctgcccggccgccggcaaccccacc
ccgtccatctcctggctgaagaacggcaaggagttccgaggcgagcaccgcatcgggggc
atcaagctgcggcaccagcagtggagcctggtcatggagagcgtggtgccttcggaccgc
ggcaactacacgtgcgtcgtggagaacaagttcggcagcatccggcagacgtacaccctg
gacgtgctggagcgctcgccgcaccggcccatcctgcaggcggggctgcccgccaaccag
acggcggtgctgggcagcgacgtggaattccactgcaaggtgtacagcgacgcgcagccc
cacatccagtggctcaagcacgtggaggtgaacggcagcaaagtggggcccgatggcacg
ccctacgtcacggtgctcaagtcgtggatcagtgagagtgcggaggctgacgtgcgcctc
cgcctggccaatgtgtccgagcgcgacgggggcgagtacctctgtcgagcctccaatttc
ataggcgtggctgagaaggccttttggctgcgtgttcgcgggccccaagcagctgaggag
gagctggtggaggctggtgaggctggcagtgtgtacgcaggtgtcctcagctacggggtg
ggcttcctcctcttcatcctggtggtggccgctgtgaccctctgccgcctgcgcagcccc
cccaagaagggcctgggctcgcccgccgtgcacaaggtctcccgcttcccgctcaagcga
cagcaggtgtccttggagtccagctcgtccatgagctccaacacgccgctggtgcggatc
gcccggctgtcctcgggggagggccctgcgctggccaacgtctctgagctcgagctgccc
gccgaccccaagtgggagctgtcccgggcccggctgactctgggcaagccactcggggag
ggctgcttcggccaggtggtcatggcggaggccatcggcatcgacaaggaccgggctgcc
aagcccgtcacggtggcggtgaagatgctgaaagatgacgccacagacaaggacctgtcg
gacctggtgtccgagatggagatgatgaagatgatcgggaagcataagaacatcatcaac
ctgctgggcgcctgcacgcagggcgggcccctgtacgtgctggtggagtacgcagccaag
ggcaacctgcgggagtacctgcgggcacggcggcccccgggcacggattactccttcgac
acttgccggctgcccgaggagcagctcaccttcaaggacctggtttcctgcgcctaccag
gtggcgcggggcatggagtaccttgcctcgcagaagtgcatccacagggacctggccgcc
cgcaacgtgctggtgaccgaggacaacgtgatgaagatcgcggacttcggcctggcccgc
gacgtgcacaacctcgactactacaaaaagaccaccaatggccgcctgcccgtgaagtgg
atggcgcccgaggccttgtttgaccgcgtctacacccaccagagtgacgtgtggtccttc
ggggtcctgctctgggagatcttcacgctggggggctcgccgtaccccggcatccccgtg
gaggagctcttcaagctgctgaaggaaggccaccgcatggacaagccagccaactgcacg
cacgacctgtacatgatcatgcgtgagtgctggcacgccgtgccctcccagaggcccacc
ttcaagcagctggtggaagacctggaccgcgtgctcaccgtcacatccaccgacgtagcg
ggggctcgcggacgtgaagggccgcggcctgcgggccaagcccccatcaacgtgagagcg
gaccccagcctgccgtgctgccgctggtgtgccgtgaccaacgggtctcaccggcctgga
ctcaagacctggaacaggtggacagatggacagacaacttccacatgtgtacgtgtgcac
acgtgtgtgctctggggtccccggcgtgcccgccctgctgtacggtga

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