Balaenoptera musculus (blue whale): 118902100
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Entry
118902100 CDS
T09887
Symbol
HSD11B1
Name
(RefSeq) corticosteroid 11-beta-dehydrogenase isozyme 1
KO
K15680
corticosteroid 11-beta-dehydrogenase isozyme 1 [EC:
1.1.1.146
]
Organism
bmus
Balaenoptera musculus (blue whale)
Pathway
bmus00140
Steroid hormone biosynthesis
bmus00980
Metabolism of xenobiotics by cytochrome P450
bmus01100
Metabolic pathways
bmus05204
Chemical carcinogenesis - DNA adducts
Module
bmus_M00109
C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
Brite
KEGG Orthology (KO) [BR:
bmus00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
118902100 (HSD11B1)
09111 Xenobiotics biodegradation and metabolism
00980 Metabolism of xenobiotics by cytochrome P450
118902100 (HSD11B1)
09160 Human Diseases
09161 Cancer: overview
05204 Chemical carcinogenesis - DNA adducts
118902100 (HSD11B1)
Enzymes [BR:
bmus01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.146 11beta-hydroxysteroid dehydrogenase
118902100 (HSD11B1)
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Motif
Pfam:
adh_short
adh_short_C2
KR
THF_DHG_CYH_C
DUF1776
2-Hacid_dh_C
Pyr_redox_2
NAD_binding_2
Pyr_redox_3
Shikimate_DH
Methyltransf_25
Pyr_redox
Motif
Other DBs
NCBI-GeneID:
118902100
NCBI-ProteinID:
XP_036721953
UniProt:
A0A8C0CHY8
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Position
1:complement(147418758..147451068)
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AA seq
294 aa
AA seq
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MAFMKKYLLPILGIFLAYYYYSAKEEFRPEMLRGKRVIVTGASKGIGREMAYHLARMGAH
VVVTARSEEALKKVVSHCLELGASSAHYVAGTMENMTFAEEFVAKAGKLMGGLDMLILNH
ITNTNNPMTVFIDDIDQVRKNMEVNFLSYVVLSGAAMPMLKQSNGSIVVVSSIAGKTANP
LIAAYSASKFALDGFFSSVRVEYAVTNVNVSITLCILGLIDTETAMTGTAGIYNAEASPK
EECALEIIKGGALRQKEVYYDSSVLTPFLLGNPGRKILEFLSLRNYNMEIFINN
NT seq
885 nt
NT seq
+upstream
nt +downstream
nt
atggcttttatgaaaaaatatctcctccccattctggggatcttcttggcctactactac
tattctgcgaaggaggaattcagaccagagatgcttcgaggaaaaagagtgattgtcaca
ggggccagcaaggggattggaagagagatggcctatcatctggcgagaatgggagcccat
gtggtagtgacagcgaggtcagaagaagctctaaagaaggtggtatcccactgcctggag
ctcggtgcatcctcggcgcactacgttgctggcaccatggagaacatgaccttcgcagag
gaatttgttgccaaagctggaaaactcatggggggactagacatgctcattctcaaccac
atcaccaacaccaacaatcctatgactgtatttattgatgacattgaccaagtgcgcaaa
aacatggaggtcaacttcctgagttatgtggtcctgagcggggccgccatgcccatgctg
aagcagagcaatgggagcattgtggttgtctcctcaatagctgggaaaacagctaatcca
ctaattgctgcctattctgcaagcaagtttgctctggatgggttcttctcctctgtcagg
gtggaatatgcagtgaccaatgtcaatgtgtcgatcaccctctgtatccttggcctcata
gacacagaaacagccatgacaggaactgctgggatatacaatgcagaagcatctccaaag
gaagaatgtgccctggagattatcaaagggggagctctgcgccaaaaggaagtgtattat
gacagttcggtcttgactcctttcctgctgggaaatccagggagaaagatcttggaattt
ctctccttacgaaattataatatggaaatatttataaacaactag
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