KEGG   Halobacteriovorax marinus: BMS_0311
Entry
BMS_0311          CDS       T01659                                 
Symbol
metH
Name
(GenBank) B12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
bmx  Halobacteriovorax marinus
Pathway
bmx00270  Cysteine and methionine metabolism
bmx00450  Selenocompound metabolism
bmx00670  One carbon pool by folate
bmx01100  Metabolic pathways
bmx01110  Biosynthesis of secondary metabolites
bmx01230  Biosynthesis of amino acids
bmx04980  Cobalamin transport and metabolism
bmx04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:bmx00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    BMS_0311 (metH)
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    BMS_0311 (metH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    BMS_0311 (metH)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    BMS_0311 (metH)
   04980 Cobalamin transport and metabolism
    BMS_0311 (metH)
Enzymes [BR:bmx01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     BMS_0311 (metH)
SSDB
Motif
Pfam: Met_synt_B12 S-methyl_trans Pterin_bind B12-binding_2 B12-binding
Other DBs
NCBI-ProteinID: CBW25236
UniProt: E1X3E1
LinkDB
Position
complement(324869..328588)
AA seq 1239 aa
MSELKPYTTMGNELLELLNKRIVFMDGAMGTMIQQYKLEEEDFRGERFKDHASPLKGNND
LLSLTRADIIEEVHFKYLEAGSDIIETNTFSATRIGQADYHLEDLAYEINVESARIAKRA
CEKMMQKDPTRKCFVAGALGPTNKTASMSPDVNNPAYRAVTFDELVENYYQQAKALLEGG
ADILLPETTFDTLNIKCAIFAIDKLFNELDYRVPVMLSVTITDASGRTLSGQTIEAFWNS
VRHANPLSVGINCALGAKEMRPYMDRLSQIADCYTSCYPNAGLPNPLSDTGYDELPIDTA
TFLEDYADSGFLNLVGGCCGTTPSHIKAIREKLEEKKPRVKPTLKEVMNLSGLEPLYIDR
EDQSRPFYMVGERTNVTGSPRFAKLIKNGDFDTALEVARQQVENGANIIDINFDEGLLDS
KACMIKFMNLVASEPEICKVPIMIDSSKWEVIEEGLKCMQGKGIVNSISLKEGEEKFIEQ
AKLIKSYGAATVVMAFDEEGQAADKADKVRICQRAYKILVEKVNFDPRDIIFDPNILTVA
TGIEEHNNYALDFIEAVKEIKETCPGVLTSGGVSNVSFSFRGNNVVREAIHSSFLYHAIK
AGLDMGIVNAGMLGVYEDIEPNLLQLVEDVLLNRHPDATEKLVDFAEKIKGSGKKKEVKD
DKWRHGTLQERMTHALVKGISTHIEEDTEEARQELGIPLNVIEGPLMEGMKVVGELFGSG
KMFLPQVVKSARVMKAAVAYLEPFMEEERKKNANARKQGTFVIATVKGDVHDIGKNIVAV
VLACNGYEVIDLGVMVSCEEIIKKAKEHDACIIGMSGLITPSLDEMIYNVKEFERLGFSC
PIMIGGATTSKAHNAIKIAPHYSGPVAQVGDASLVVEVCSKLLNPTTAPAYTKELKEHQA
KLKERFDLGKQDQSKLVSLEQSREWKFICDWEKQEIATPSFTGIKKYLDVSLEEIVPYID
WSPLFWTWQLKGTYPKILNNEKYGEQAKSLFKDANIILEKVIAEKRFSPKAIVSIHKANS
IGDDVEVYDDNGKKIETFHYLRQQKEKSEHKPHLCLSDYIAPKESGREDYLGNFVVTMGH
EVEEFAKIYEQRNDDYNAIMVKAIGDRLAEAFAEYMHKVIRDEFGYGKEENFSNEDLIKE
KYRGIRPAPGYPSCPDHTEKPIMWDLLNVESEIGVSLTENCAMNPPSSVSGQYFCHPGAK
YFTLGPIARDQVENYSKRKDMEIKRVERWLAPNLGYNPE
NT seq 3720 nt   +upstreamnt  +downstreamnt
atgtcagaattaaaaccatatacaacaatgggtaatgaattactcgagctattgaataaa
agaattgttttcatggatggagctatgggaacaatgattcagcaatataagttagaagaa
gaagactttagaggagagagatttaaagatcacgctagtccactaaaaggaaataatgat
cttctctctcttacacgcgccgatattattgaagaagttcacttcaagtacctcgaggcc
ggttctgatattatcgagacaaatacgtttagtgcgacaagaattgggcaggcggattac
catctagaggatcttgcttatgaaataaatgttgagtccgctcgcattgctaaaagagca
tgtgaaaagatgatgcaaaaagatcctacaagaaaatgctttgttgccggagctctcggc
ccaacgaataagacggcttccatgtcaccagacgtaaacaaccctgcttacagagcagtt
acatttgatgagttagttgaaaattactatcagcaggccaaagctcttttagaaggtgga
gctgatatcctacttccagaaacaactttcgacactttgaatattaagtgtgcgatcttt
gctattgataaattatttaatgaactagattacagagtaccagtaatgttatcagtaaca
attactgatgcatcaggaagaactctatctggtcaaacaattgaggccttctggaattca
gttagacatgcaaatccacttagtgtgggtatcaattgtgctcttggtgctaaagaaatg
cgtccttatatggatcgtctttcgcaaattgcggactgctatacaagttgttatccaaat
gcaggtcttcccaatccgctgagtgatacagggtatgacgaactacctattgatacagca
acattcttagaagattacgcagactctggcttcttaaatcttgtaggaggatgttgtggg
acaacaccttctcacattaaggcgattagagaaaagcttgaagagaaaaagccaagagtt
aagccaactcttaaagaagtgatgaacctctctggtcttgagcctctctatattgataga
gaagatcagtctcgcccattttatatggttggagaaagaactaatgtcacgggctctcca
aggtttgcaaagcttattaaaaatggtgactttgacacagctcttgaagtagcgaggcaa
caggttgagaatggtgccaacattattgatatcaactttgatgaaggtctcctcgactcc
aaagcatgtatgatcaaatttatgaatctcgtagcatcagagcctgagatttgtaaggtt
cccataatgattgatagttcaaaatgggaagttatcgaagaaggtcttaagtgtatgcaa
ggaaagggaatcgtaaattccatttctttgaaagagggggaagagaagtttattgagcaa
gcaaagcttatcaaatcctatggtgcggccactgtagtcatggccttcgatgaagagggg
caagccgctgataaagcagataaagttagaatttgccaaagggcctataagatattggtt
gaaaaagttaactttgaccctagagatattatttttgacccaaatattctaaccgtggcc
accggaattgaagagcataataattacgctcttgattttatcgaagcggtaaaagaaatt
aaggaaacttgtccaggagttctaacaagtggtggagtttcaaacgtttctttttcattt
cgaggcaataatgtcgtaagagaagcaattcactcatcatttctctatcacgcgatcaag
gccggattagatatgggaattgtaaacgccgggatgcttggtgtttacgaagatattgaa
cctaatctcctacaattggtggaagatgttctgttaaatagacatccagatgccacagag
aagctagtagactttgctgagaagattaaaggttcgggaaagaagaaagaagttaaagat
gacaagtggagacatggaactcttcaagagagaatgactcacgcccttgttaaaggtatt
tcaactcatattgaagaagatacagaagaagccagacaagaattaggaattcctctcaat
gttattgagggacctttgatggaaggaatgaaagttgtgggagagctttttggctcaggg
aaaatgttcctacctcaagttgttaaatccgccagggtaatgaaggcagccgtcgcttat
cttgaaccatttatggaagaagagagaaagaagaatgccaatgctagaaagcagggaaca
tttgtcatcgctactgttaaaggtgacgttcatgatatcggaaagaatattgttgcagtt
gttctcgcttgtaatggctacgaagtcattgatctaggagtcatggttagctgcgaagaa
attattaaaaaggccaaggagcacgacgcctgtattatcggaatgagtggactgattacc
ccttctcttgatgagatgatctataacgtaaaagaatttgaaaggctcggttttagctgt
ccaattatgattggaggggccacaacaagtaaggcccacaatgcaatcaagattgctcca
cactatagtggaccagtcgcccaagttggagatgcttctctcgttgtagaagtatgctca
aaactcttgaaccctacaactgcccctgcttatacgaaagagcttaaagagcatcaagca
aagctaaaagagcgttttgatctcggcaagcaggatcaaagtaaattagtatctttagag
caatctagagagtggaagttcatttgtgactgggaaaagcaagagattgccactccaagc
tttactggaataaagaagtatctagatgtatcgcttgaggaaattgttccttatatcgat
tggtcacctcttttttggacgtggcaacttaaaggtacctatcctaaaattttaaataat
gaaaagtatggtgagcaagcaaagtctttatttaaagatgctaatattattttagaaaaa
gttattgcagagaagagattctcacctaaggccattgtatcaattcacaaagccaactct
attggcgatgatgttgaagtctacgatgataatggaaagaagattgaaacatttcattat
ctaagacagcaaaaagaaaagtcggaacataagcctcacctctgccttagtgactatatt
gcgccaaaggaatctggaagagaagattacctcggaaactttgttgtaacaatgggacat
gaagttgaggagtttgcaaaaatctatgagcaaagaaacgatgactacaacgccattatg
gttaaggccattggagatcgtcttgctgaagcctttgccgaatatatgcacaaagtaata
agagatgagtttggttatggaaaagaagagaatttcagcaatgaagatctcatcaaagag
aagtatagagggataagacctgcaccaggctacccttcttgtccagaccacacagagaag
cctatcatgtgggaccttctaaatgtagagagtgagattggtgtttctctaacagagaat
tgcgcaatgaatcctccatcttcagtctcaggacagtatttctgtcaccctggtgctaag
tactttacgctcggcccgattgcaagagatcaagtagagaactactctaagagaaaagat
atggaaattaagagagttgagagatggcttgcaccaaatcttggctataacccagagtaa

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