Brucella melitensis M28: BM28_A1128
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Entry
BM28_A1128 CDS
T01852
Symbol
ispF
Name
(GenBank) bifunctional 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase/2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase protein
KO
K12506
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase / 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [EC:
2.7.7.60
4.6.1.12
]
Organism
bmz
Brucella melitensis M28
Pathway
bmz00900
Terpenoid backbone biosynthesis
bmz01100
Metabolic pathways
bmz01110
Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:
bmz00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
00900 Terpenoid backbone biosynthesis
BM28_A1128 (ispF)
Enzymes [BR:
bmz01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.7 Nucleotidyltransferases
2.7.7.60 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
BM28_A1128 (ispF)
4. Lyases
4.6 Phosphorus-oxygen lyases
4.6.1 Phosphorus-oxygen lyases (only sub-subclass identified to date)
4.6.1.12 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
BM28_A1128 (ispF)
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Paralog
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Motif
Pfam:
YgbB
IspD
NTP_transf_3
Motif
Other DBs
NCBI-ProteinID:
ADZ66204
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All DBs
Position
1:1117322..1118665
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AA seq
447 aa
AA seq
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MKSAYSLITPLSERKEKQPERTINQLPSGICRRKALFGLQAQSLAEVTVISKAAAVIVAA
GRGERAGQSAEGPKQYRLIGAEAVLARTLRAFTDCPLIGTIAVVIHPDDHALYRRAVPEK
HENVILVTGGPTRQESTRLGLLALKDEAPQYVLIHDGVRPFIGQDLLERIIANLTPDNGV
LPALAVSDTLKRAAADGMVETTISRTGLFAAQTPQAFPYAPILDAHEKAFAINRTDFTDD
AAIAEWQEIAVRIIEGSADNTKLTWAKDIEMADKRLRQDHAVFPDIRTGNGYDVHSFEPG
DHVTLCGVKIPHEAKLNGHSDADVALHALTDALLATRGAGDIGTHFPPSDPQWKGAASRI
FIEHAAKIVREAGGRIANVDVTLISEAPKIGPHRAAMTQALCDMLGIAADRVSIKATTNE
KLGFVGRREGIAAIATATVIYPGEVPE
NT seq
1344 nt
NT seq
+upstream
nt +downstream
nt
atgaaatccgcatacagtttaatcaccccgctttccgaacgcaaggaaaagcagcctgaa
cgcacgataaatcaattgccgtctggcatttgtcgtcgcaaggccttattcggcttgcag
gcacaatctttggcagaggttacagtcatttcaaaggcagcagcagtcatcgtggcggcc
ggtcgcggcgagcgggcggggcaaagcgccgaggggccgaagcaatatcggctcattggc
gcagaggccgtgcttgcccgcactttgcgcgcttttaccgattgcccgctcatcggcaca
atcgccgtcgtcattcatcccgacgatcatgcgctttatcggcgcgctgtgccggagaag
catgagaacgtcatcctcgttaccggtggccccacccgacaggaatcgacccgcctcggt
cttctggccttgaaggacgaagcgccgcaatatgtgttgatccatgatggcgtgcgtcct
ttcatcggtcaggatttgctggaacgcatcattgcaaacctcacccctgataatggtgtg
cttcccgccctcgccgtctccgacacgttgaaacgggcggcggcagacggcatggtagag
accaccatttcccgtaccggcttgttcgcggcgcagacgccgcaagcttttccctatgcg
ccgatcttggacgcacatgagaaagccttcgcaatcaaccgcaccgactttaccgacgat
gccgccattgccgaatggcaggaaattgctgttcgcattatcgaaggttcggcggataat
acaaagctcacctgggcaaaggatattgaaatggcagacaagcgcctgcggcaggaccat
gccgtatttcccgacattcgcacgggcaatggctatgatgttcattctttcgagccgggt
gatcatgtcacgctttgcggcgtgaaaatcccccatgaggcaaagctcaacggtcactcc
gatgccgatgtggcccttcatgcgctgaccgacgccctgctcgccacgcgcggtgcgggt
gatattggcacacattttccgccatccgatccgcaatggaaaggagctgcctcacgcatc
ttcatcgaacatgcggccaaaatcgtccgcgaggcgggaggccggatcgccaatgtggac
gtgacactcatcagtgaagcgccgaagatcggcccccatcgcgccgccatgacacaagca
ctctgcgacatgctgggcatcgccgccgaccgggtttccatcaaggctacgacgaacgaa
aagcttggctttgtcggccgtcgcgaaggcattgcagccatcgcaaccgcaaccgtcatc
taccccggagaagtaccggaatga
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