Bos mutus (wild yak): 102273597 Help Entry 102273597         CDS       T02919                                  Symbol IRS4 Name (RefSeq) insulin receptor substrate 4   KO K17446   insulin receptor substrate 4 Organism bom  Bos mutus (wild yak) Pathway bom04022   cGMP-PKG signaling pathway bom04068   FoxO signaling pathway bom04081   Hormone signaling bom04140   Autophagy - animal bom04152   AMPK signaling pathway bom04211   Longevity regulating pathway bom04213   Longevity regulating pathway - multiple species bom04910   Insulin signaling pathway bom04920   Adipocytokine signaling pathway bom04923   Regulation of lipolysis in adipocytes bom04930   Type II diabetes mellitus bom04935   Growth hormone synthesis, secretion and action bom05010   Alzheimer disease Brite KEGG Orthology (KO) [BR:bom00001]  09130 Environmental Information Processing   09132 Signal transduction    04068 FoxO signaling pathway     102273597 (IRS4)    04022 cGMP-PKG signaling pathway     102273597 (IRS4)    04152 AMPK signaling pathway     102273597 (IRS4)   09133 Signaling molecules and interaction    04081 Hormone signaling     102273597 (IRS4)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     102273597 (IRS4)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     102273597 (IRS4)    04923 Regulation of lipolysis in adipocytes     102273597 (IRS4)    04920 Adipocytokine signaling pathway     102273597 (IRS4)    04935 Growth hormone synthesis, secretion and action     102273597 (IRS4)   09149 Aging    04211 Longevity regulating pathway     102273597 (IRS4)    04213 Longevity regulating pathway - multiple species     102273597 (IRS4)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     102273597 (IRS4)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     102273597 (IRS4) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  IRS PH_11 Motif Other DBs NCBI-GeneID:  102273597 NCBI-ProteinID:  XP_070222032 LinkDB All DBs Position X:complement(108601572..108617994) Genome browser AA seq 1254 aa AA seqDB search MASCSFARDQATRRLRAAVAATAAGLAAAATTPFLSSGTPTALIGTGSSCPGAMWLSTAT GSRSDSESDEEDLPVGDEVCKRGYLRKQKHGHWRYFVLKLETADAPARLEYYENARKFRH SVRAAAAAAAAAASGATVPALIAPRRVITLYQCFSVSQRADARYPHLIALFTQNEYFAMV AENESEQESWYLLLSRLILESKRRRCGRLGAQPEGEPAALAAAAAAEPPFYKDVWQVIVK PRGLGHRKELSGVFRLCLTDEEVLFVRLNTEVASVVVQLLSIRRCGHSEQYFFLEVGRST VIGPGELWMQVDDCVVAQNMHELFLEKMRALCADEYRARCRSYSISIGGHLLTLLSTRRH LDMLPLEPGGWFRRSRFEQFCHLRAIGDGEDEMLLAGRYITPSEPVPRSRRGRLHLPRGR RSRRATSVPASFFRRAAPSPVRIRYPAEALHDRDPVSSEASSSGSGNSGEEGGPQRKEDQ EENEGDYMPMNNWGSGNGRGSGSGQGSSGQGSSSQSSGGSQCSGRGHGSGGGQGSSSSHG SSGSGSGDQSAGGNQCSGDGQGTAGHGSGSGQGAGGGHGSGRDQGAGDGHGSGGGKNSGG GKGSGSGKGPEGNGDRGKSLKKRSYFGKLTQSKQQQMPPPPPPPPPPGAATGGKGKSGGR FRLYFCADRGATKERKEAKEVKDTEPPEGAARGPHRARAFDEDEDDPYVPMRPGVAAPLA SSSDYMPMAPQNVSVSKKRHSRSPFEDSRGYMMMFPRVSPPPVPSPPKEPDPAKEDDSKD NDSDSDYMFMAPGAGAIPKNPRNPQGGSSSKSWSSYFSLPNPFRSSPLGQSDHSEYVPML PGKFLGKGLEKEVSSNRGPKDTASKPSVKGSFSKPRDGGSPSKRSGDGPPKNKAKRPNRL PFMTKGNKVKPKPQKPTQEQREADSPRGYVNIDFPKRGYNMPDPCLQRLPGVWGIIADPR QFAFSNYVNVEFGVPFPNPADNLSDFFRAIPGANPFFLDGATGSSANREEGDYIEVIFNP AMTPAVPFADSAIRYDAETGRIYVVDPFSECCMNISLSPSRCSERPPVARLLLLEELDRR RPQSRSQSFFAAARAAISAFPTDSLERDLSASFAAAAAAVPTLALGRALAAASALVAAPG IGAAAAGLEAAAGFDSASVRWFLPVADAAGAAVRGAQDIAGGSNPRPPNPSADLAGGENR AGGAAAAVAAAPRSPGRGRVPRPPEREDSDDDDTYVRMDFARRDNGKFDSPQRE NT seq 3765 nt NT seq  +upstreamnt  +downstreamnt atggctagttgctccttcgctcgcgaccaagcgacaaggagactgcgagctgcagtagcg gcaacagcggcgggtctagctgcggcggcgaccaccccatttctttcctcgggaaccccc accgcactcattgggaccgggtcgtcttgtccgggagccatgtggctctccacggccact ggctcccggtcagactcggagtccgacgaggaggaccttcccgtcggggacgaagtctgc aaacgcggctacctgcggaagcagaagcatgggcactggcgctacttcgtgctcaaactc gagacagccgacgccccagctcggctggaatactacgaaaatgccaggaagttccggcac agtgtccgcgccgcggcggctgcagcggcggcggccgcctctggcgccacggtccccgcg ctcattgcaccgcggcgcgtgatcaccctgtaccagtgcttctcggtgagccagcgggcc gacgcaaggtacccacacctcattgctcttttcacccaaaacgagtatttcgcaatggtg gcagagaatgagtcggagcaagagagctggtacttgctgctcagccgcctcatcctcgag agcaagcgccgccgctgcggcaggctcggcgcgcagccggagggagagccggccgcgcta gcagctgcagcggcggcagagccacccttctacaaagatgtgtggcaagtaatagtcaaa cccagggggctggggcaccgaaaagagctgagcggcgtgttccggctctgtcttaccgac gaggaggttctgtttgtgaggttaaataccgaagtggccagcgtggttgtccagctcctg agcatccgtcgctgtgggcactcggagcagtatttcttcttggaagtcggcaggtccacc gtcatcggtccgggggagctctggatgcaagtggatgactgtgtcgtggcccaaaacatg cacgagctgtttttggagaagatgagagccttgtgtgcagacgaatacagagcccgctgc cgcagctacagcatcagcatcggcggccacctgttaaccctgctgtccactaggaggcac ctggacatgctgccgctcgagcccggcggctggttccgaaggtcccgctttgagcagttt tgccaccttcgggccatcggtgacggggaagacgaaatgctcctcgccgggcgctacata acacccagtgagccagtgccccgctccagacgaggaagactacacctgcccagagggcgc agatccaggagagcgacttcagtgccagccagctttttccgccgcgccgctcccagccct gtgcgcatccggtaccctgcagaagccctccacgaccgagatcccgtgtcttctgaagcc tctagttctggctctggcaattcaggggaagaaggcggtcctcagcgcaaagaggatcag gaagaaaacgaaggtgactatatgcccatgaacaactggggctcgggaaatggccggggc tcaggaagtggacagggttcaagtgggcaaggctccagtagccaaagctccgggggaagt cagtgctcaggcagggggcatggctccggaggtggtcagggctcaagtagcagccatggc tcaagtggcagcggttccggggaccagagtgcaggaggaaaccagtgctctggggatggc cagggcaccgctgggcatggctcaggcagtggccagggagctggaggtgggcatggctca ggccgtgaccagggagccggagatggccatggctcaggcggtggcaagaactctggaggg ggcaaaggctcagggagtgggaaggggcctgaaggcaatggtgatcgtgggaaatctctg aagaaaagatcctactttggcaaattaactcaaagcaagcaacagcaaatgccaccacct ccgccccctccacccccaccaggtgcagcaactggtggcaaagggaagtctgggggaagg ttccgactttatttttgtgcagacagaggggccacaaaagaacgcaaagaagccaaagaa gtgaaagacacagagcccccagaaggtgcagctcggggtccccacagagccagagctttt gatgaagacgaggatgatccgtatgtgccaatgaggccaggcgtggctgctcctctcgca agctccagtgactacatgcccatggctcctcaaaatgtctctgtgtccaaaaagcgccac tctcgatcaccttttgaagattctagagggtacatgatgatgtttcccagagtgagccca ccacctgtgccaagtcctccaaaagaacctgatcctgctaaagaggacgactcaaaggac aatgacagtgacagtgactatatgttcatggcccctggagctggtgccattcctaaaaac cccagaaatcctcagggaggctcttcctccaaaagttggagctcctacttctctctgcca aatccttttcggagctccccattgggacagagtgaccacagtgagtatgtaccaatgtta cctggaaaattcctaggaaagggcctagagaaggaagtctcatctaacagaggccccaaa gatacagcttcaaagccttcagtcaaagggtctttctcaaagcctagagatgggggatca ccttccaagcgttcaggtgacgggccccccaagaacaaggctaagagacctaatcgactt ccttttatgacaaaaggaaacaaagtcaagccaaaaccacaaaagcccacacaggagcag agagaagccgacagccccaggggctacgtcaacattgacttccctaagagaggttataat atgccagatccatgtcttcaaagacttccaggtgtgtggggcataattgccgaccccaga cagtttgccttttccaattacgtgaatgttgagttcggagtgccatttccaaatccagca gacaacctctcagatttcttcagagctatcccaggtgccaatcccttctttctggacggt gctaccgggagcagtgctaatagggaagaaggtgactacatcgaagtgattttcaaccca gcgatgacaccagctgtgccttttgctgacagtgccattcgctacgatgccgaaactggt cgcatctacgtggtcgacccattttctgagtgctgtatgaacatttctctctcccccagc cgctgctccgaacgaccacctgtagcgaggctgctactgctagaagagctcgatcgaagg cgcccacaaagccgttcgcaaagtttctttgcagccgccagagccgccatctctgctttc cctacagacagcctcgagagagacctatccgcctccttcgccgcggccgcggccgccgtg ccaaccttagccctgggccgggctttagccgccgcctccgctttggtcgcggctcccggc atcggcgcagcagccgccggcctcgaggccgccgctggatttgactccgcctccgtccgc tggttcctacctgttgccgatgctgctggtgccgcggtcaggggggcccaagacattgcg ggtggctcgaaccccagacccccaaacccatcagcagacctggccggaggtgagaaccga gccggtggggctgctgctgcagtcgccgctgcgcctcgatcacctggccgcggccgggtg cccagacccccagagcgagaagattctgacgacgacgacacgtacgtgagaatggacttt gcaagacgtgacaacgggaagttcgactctccccaaagagagtga

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