Bos mutus (wild yak): 102276460 Help Entry 102276460         CDS       T02919                                  Symbol ADCY5 Name (RefSeq) adenylate cyclase type 5   KO K08045   adenylate cyclase 5 [EC:4.6.1.1] Organism bom  Bos mutus (wild yak) Pathway bom00230   Purine metabolism bom01100   Metabolic pathways bom01522   Endocrine resistance bom04015   Rap1 signaling pathway bom04022   cGMP-PKG signaling pathway bom04024   cAMP signaling pathway bom04062   Chemokine signaling pathway bom04072   Phospholipase D signaling pathway bom04081   Hormone signaling bom04082   Neuroactive ligand signaling bom04114   Oocyte meiosis bom04211   Longevity regulating pathway bom04213   Longevity regulating pathway - multiple species bom04261   Adrenergic signaling in cardiomyocytes bom04270   Vascular smooth muscle contraction bom04371   Apelin signaling pathway bom04540   Gap junction bom04611   Platelet activation bom04713   Circadian entrainment bom04714   Thermogenesis bom04723   Retrograde endocannabinoid signaling bom04724   Glutamatergic synapse bom04725   Cholinergic synapse bom04726   Serotonergic synapse bom04727   GABAergic synapse bom04728   Dopaminergic synapse bom04750   Inflammatory mediator regulation of TRP channels bom04911   Insulin secretion bom04912   GnRH signaling pathway bom04913   Ovarian steroidogenesis bom04914   Progesterone-mediated oocyte maturation bom04915   Estrogen signaling pathway bom04916   Melanogenesis bom04918   Thyroid hormone synthesis bom04921   Oxytocin signaling pathway bom04923   Regulation of lipolysis in adipocytes bom04924   Renin secretion bom04925   Aldosterone synthesis and secretion bom04926   Relaxin signaling pathway bom04927   Cortisol synthesis and secretion bom04928   Parathyroid hormone synthesis, secretion and action bom04934   Cushing syndrome bom04935   Growth hormone synthesis, secretion and action bom04970   Salivary secretion bom04971   Gastric acid secretion bom04972   Pancreatic secretion bom04976   Bile secretion bom05012   Parkinson disease bom05030   Cocaine addiction bom05031   Amphetamine addiction bom05032   Morphine addiction bom05034   Alcoholism bom05163   Human cytomegalovirus infection bom05166   Human T-cell leukemia virus 1 infection bom05200   Pathways in cancer bom05207   Chemical carcinogenesis - receptor activation bom05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:bom00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     102276460 (ADCY5)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     102276460 (ADCY5)    04371 Apelin signaling pathway     102276460 (ADCY5)    04072 Phospholipase D signaling pathway     102276460 (ADCY5)    04024 cAMP signaling pathway     102276460 (ADCY5)    04022 cGMP-PKG signaling pathway     102276460 (ADCY5)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     102276460 (ADCY5)    04081 Hormone signaling     102276460 (ADCY5)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     102276460 (ADCY5)   09144 Cellular community - eukaryotes    04540 Gap junction     102276460 (ADCY5)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     102276460 (ADCY5)    04062 Chemokine signaling pathway     102276460 (ADCY5)   09152 Endocrine system    04911 Insulin secretion     102276460 (ADCY5)    04923 Regulation of lipolysis in adipocytes     102276460 (ADCY5)    04912 GnRH signaling pathway     102276460 (ADCY5)    04913 Ovarian steroidogenesis     102276460 (ADCY5)    04915 Estrogen signaling pathway     102276460 (ADCY5)    04914 Progesterone-mediated oocyte maturation     102276460 (ADCY5)    04921 Oxytocin signaling pathway     102276460 (ADCY5)    04926 Relaxin signaling pathway     102276460 (ADCY5)    04935 Growth hormone synthesis, secretion and action     102276460 (ADCY5)    04918 Thyroid hormone synthesis     102276460 (ADCY5)    04928 Parathyroid hormone synthesis, secretion and action     102276460 (ADCY5)    04916 Melanogenesis     102276460 (ADCY5)    04924 Renin secretion     102276460 (ADCY5)    04925 Aldosterone synthesis and secretion     102276460 (ADCY5)    04927 Cortisol synthesis and secretion     102276460 (ADCY5)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     102276460 (ADCY5)    04270 Vascular smooth muscle contraction     102276460 (ADCY5)   09154 Digestive system    04970 Salivary secretion     102276460 (ADCY5)    04971 Gastric acid secretion     102276460 (ADCY5)    04972 Pancreatic secretion     102276460 (ADCY5)    04976 Bile secretion     102276460 (ADCY5)   09156 Nervous system    04724 Glutamatergic synapse     102276460 (ADCY5)    04727 GABAergic synapse     102276460 (ADCY5)    04725 Cholinergic synapse     102276460 (ADCY5)    04728 Dopaminergic synapse     102276460 (ADCY5)    04726 Serotonergic synapse     102276460 (ADCY5)    04723 Retrograde endocannabinoid signaling     102276460 (ADCY5)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     102276460 (ADCY5)   09149 Aging    04211 Longevity regulating pathway     102276460 (ADCY5)    04213 Longevity regulating pathway - multiple species     102276460 (ADCY5)   09159 Environmental adaptation    04713 Circadian entrainment     102276460 (ADCY5)    04714 Thermogenesis     102276460 (ADCY5)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     102276460 (ADCY5)    05207 Chemical carcinogenesis - receptor activation     102276460 (ADCY5)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     102276460 (ADCY5)    05163 Human cytomegalovirus infection     102276460 (ADCY5)   09164 Neurodegenerative disease    05012 Parkinson disease     102276460 (ADCY5)   09165 Substance dependence    05030 Cocaine addiction     102276460 (ADCY5)    05031 Amphetamine addiction     102276460 (ADCY5)    05032 Morphine addiction     102276460 (ADCY5)    05034 Alcoholism     102276460 (ADCY5)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     102276460 (ADCY5)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     102276460 (ADCY5)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     102276460 (ADCY5) Enzymes [BR:bom01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      102276460 (ADCY5) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  AC_N Guanylate_cyc Adcy_cons_dom TBK1_ULD GBR2_CC Motif Other DBs NCBI-GeneID:  102276460 NCBI-ProteinID:  XP_070226335 LinkDB All DBs Position 1:complement(66768943..66927816) Genome browser AA seq 1259 aa AA seqDB search MSSSKSVSPPGYAAQTAAAPASRGGPEHRSAWGEADSRANGYPQAPGGSARGSTKRPGGA VTPQQQQRLASRWRSDDEDDPPLSGDDPLAGGFGFSFRSKSAWQERGGDDCGRGSRRQRR GAAGGGSTRAPPAGSGGGSAAAAAAAGGTEVRPRSVELGLEERRGKGRAADDLEAGAVEE DEGSGDGGSSAGSGAGPGAVLSLGACCLALLQIFRSKKFPSDKLERLYQRYFFRLNQSSL TMLMAVLVLVCLVMLAFHAARPPLQLPYLAVLAAAVGVILVMAVLCNRAAFHQDHMGLAC YALIAVVLAVQVVGLLLPQPRSASEGIWWTVFFIYTIYTLLPVRMRAAVLSGVLLSALHL AIALRTNAQDQFLLKQLVSNVLIFSCTNIVGVCTHYPAEVSQRQAFQETRECIQARLHSQ RENQQQERLLLSVLPRHVAMEMKADINAKQEDMMFHKIYIQKHDNVSILFADIEGFTSLA SQCTAQELVMTLNELFARFDKLAAENHCLRIKILGDCYYCVSGLPEARADHAHCCVEMGM DMIEAISLVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAGGKAG RIHITKATLNYLNGDYEVEPGCGGERNAYLKEHSIETFLILRCTQKRKEEKAMIAKMNRQ RTNSIGHNPPHWGAERPFYNHLGGNQVSKEMKRMGFEDPKDKNAQESSNPEDEVDEFLGR AIDARSIDRLRSEHVRKFLLTFREPDLEKKYSKQVDDRFGAYVACASLVFLFICFVQITI VPHSVFMLSFYLTCFLLLTLVVFVSVIYSCVKLFPAPLQTLSRKIVRSKMNSTLVGVFTI TLVFLSAFVNMFTCNSKDLFGCLGDEHNISASQVNACHVVESAVNYSLGDEQGFCGSSWP NCNFPEYFTYSVLLSLLACSVFLQISCIGKLVLMLAIELIYVLVVEVPGVTLFDNADLLV TANAIDFSNNGTSQCPEHPTKVALKVVTPIIISVFVLALYLHAQQVESTARLDFLWKLQA TEEKEEMEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQSCECVAVMFASIANFSE FYVELEANNEGVECLRLLNEIIADFDEIISEDRFRQLEKIKTIGSTYMAASGLNDSTYDK VGKTHIKALADFAMKLMDQMKYINEHSFNNFQMKIGLNIGPVVAGVIGARKPQYDIWGNT VNVASRMDSTGVPDRIQVTTDMYQVLAANTYQLECRGVVKVKGKGEMMTYFLNGGPPPS NT seq 3780 nt NT seq  +upstreamnt  +downstreamnt atgtccagctccaaaagcgtgagccccccgggctacgcggcgcagacagcggcggcgccg gcgtcccggggaggcccggaacaccgctccgcgtggggagaggccgactcccgcgccaat ggctacccccaagcccccgggggttcggcccgcggctccaccaagagacctgggggggcg gtgaccccgcagcagcaacagcgcctggccagccgctggcgcagcgacgacgaagacgat cctccgctgagtggcgatgaccccctggccgggggcttcggcttcagcttccgttccaag tcggcctggcaggagcgcggcggcgacgactgcggtcgcggcagccggcggcagcggcgg ggcgcggccggcgggggcagcacccgggcgccccctgcgggcagcggcggcggttcggcg gctgcggccgccgcagcgggcgggacggaggtgcgcccccgttcggtggagctaggcctg gaggagcggcgtggcaagggccgcgcggccgacgatctggaggccggcgccgtcgaggaa gacgaagggtccggggatgggggcagctcggcaggctcgggcgcggggcctggcgcggtg ctgtcgctgggcgcctgctgcctggcactgctgcagatattccgctctaagaagttccca tcggacaagctggagcggctgtaccagcgctacttcttccgtctgaaccagagcagcctc acaatgctcatggctgtgctggtgctcgtgtgcctagtcatgttggccttccacgcggca cggcccccgctgcagctgccctacctggccgtcctagcggccgccgtgggtgtgatcctc gttatggccgtgctctgcaaccgcgccgccttccaccaggaccacatgggcctggcctgc tacgcgcttatcgccgtggtgctggccgtccaggtggtgggcctgttgctgccccagccg cgcagtgcctccgagggcatctggtggactgtgtttttcatctatacgatctacacgctc ctgcccgtgcgcatgcgggctgcggtactcagcggggtgctcctgtccgccctccacctg gccatcgccctgcgcaccaacgcccaggatcagttcctgctcaagcagctcgtctccaac gtcctcattttctcctgcaccaacattgtgggtgtgtgcacccactacccggctgaggtc tcgcagaggcaggccttccaggagacccgggagtgcatccaggcacggctccactcacag cgggagaaccagcagcaggagcggctcctgctgtctgtccttccccgtcacgttgccatg gagatgaaagccgacatcaacgccaaacaggaggatatgatgttccataagatttacatc cagaaacatgacaacgtgagcatcctgtttgctgacatcgagggtttcaccagcctggca tcccagtgcactgcccaggagctggtcatgaccctcaacgagctcttcgcccgcttcgac aagctggctgcggagaatcactgtttacgtattaagatcctgggagattgttattactgt gtctcagggctgcctgaagccagggctgaccacgcccactgctgcgtggagatgggcatg gacatgatcgaggccatctcgctggtccgggaggtgacaggtgtgaacgtgaacatgcgt gtgggaattcacagcgggagagtgcactgcggtgtcctcggcctcaggaagtggcagttc gatgtctggtctaacgatgtcacactggccaaccacatggaggctggaggcaaggcggga cgcatccacatcaccaaggccactctcaactacttgaatggtgactacgaagtggagcca ggctgtgggggcgagcgcaacgcctacctcaaggagcacagtatcgagacctttctcatc ctgcgctgcacccagaagcggaaagaagagaaggccatgattgccaagatgaaccgtcag agaaccaactccatcgggcacaacccgccccactggggggccgagcgccccttctataac cacctggggggcaaccaggtgtccaaggagatgaagcggatgggctttgaagaccccaag gacaagaatgcccaggaaagttcgaaccctgaggatgaagtggatgaatttctgggccgt gccattgatgccaggagcatcgacaggctgcgatctgaacatgttcgcaagttcctcttg accttcagggagcctgacttagagaagaagtactccaagcaggtggatgaccgatttggt gcctacgtggcctgtgcctcgctcgtcttcctcttcatctgctttgtccagatcaccatt gtgccccactccgtgttcatgttgagtttctacctgacctgtttcctgctgctgaccttg gtggtgtttgtgtccgtgatctattcttgcgtgaagctcttcccagccccgctgcagacg ctctccaggaagatcgtgcggtccaagatgaacagcaccctggtgggggtgttcaccatc accctcgtgttcctgtcggctttcgtcaacatgttcacgtgcaactccaaggacctgttt ggctgcctgggggacgagcacaacatcagtgccagtcaggtcaatgcatgccacgtggtg gagtcggccgtcaactacagtctgggtgacgagcagggcttctgcggcagctcctggccc aactgcaacttccccgagtacttcacctatagcgtgctgctcagcctgctggcctgctcc gtgttcctgcagatcagctgcatcgggaagctggtgctcatgctggccatcgagctcatc tacgtgctcgtcgttgaggtgcccggtgtcacgctctttgacaatgccgacctactggtc acggccaacgccatagacttcagcaacaacgggacctcccagtgccctgagcatccaacc aaggtggcgctgaaggtggtgacgcccatcatcatctccgtcttcgtgctggccctgtac ctgcatgcccagcaggtggagtccactgcccgcctcgacttcctctggaaacttcaggcc acggaggagaaggaggagatggaggagctgcaggcctacaaccggcggctgctgcacaac attctgcccaaggacgtggccgcacacttcctggcccgcgaacggcgcaacgacgagctc tactatcagtcgtgcgagtgcgtggccgtcatgttcgcctccatcgccaacttctctgag ttctatgtggaactagaggccaacaacgagggcgtcgagtgcctgcggctactcaacgag atcatcgcagactttgacgagatcattagtgaggaccggttcaggcagctggaaaagatc aagaccatcggcagcacctacatggccgcctccggcctcaatgactccacctacgacaag gtgggcaagacccacatcaaagccctggccgacttcgccatgaagttgatggaccaaatg aagtacatcaacgagcactctttcaacaacttccagatgaagatcgggctcaatattggc cccgtggtggcgggtgtgattggagcccgcaagcctcagtacgacatctggggcaatacg gtgaacgtggccagccgcatggacagcaccggtgtgcccgaccgcatccaggtcaccaca gacatgtaccaggtgctggccgccaatacgtaccagctggagtgccggggtgtggtcaag gtcaagggcaaaggcgagatgatgacctacttcctcaacggaggacccccgcccagttag

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