Bos mutus (wild yak): 102286011 Help Entry 102286011         CDS       T02919                                  Symbol JAK3 Name (RefSeq) tyrosine-protein kinase JAK3   KO K11218   Janus kinase 3 [EC:2.7.10.2] Organism bom  Bos mutus (wild yak) Pathway bom04062   Chemokine signaling pathway bom04151   PI3K-Akt signaling pathway bom04217   Necroptosis bom04550   Signaling pathways regulating pluripotency of stem cells bom04630   JAK-STAT signaling pathway bom04658   Th1 and Th2 cell differentiation bom04659   Th17 cell differentiation bom05161   Hepatitis B bom05162   Measles bom05166   Human T-cell leukemia virus 1 infection bom05169   Epstein-Barr virus infection bom05200   Pathways in cancer bom05203   Viral carcinogenesis bom05223   Non-small cell lung cancer bom05340   Primary immunodeficiency Brite KEGG Orthology (KO) [BR:bom00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     102286011 (JAK3)    04151 PI3K-Akt signaling pathway     102286011 (JAK3)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     102286011 (JAK3)   09144 Cellular community - eukaryotes    04550 Signaling pathways regulating pluripotency of stem cells     102286011 (JAK3)  09150 Organismal Systems   09151 Immune system    04658 Th1 and Th2 cell differentiation     102286011 (JAK3)    04659 Th17 cell differentiation     102286011 (JAK3)    04062 Chemokine signaling pathway     102286011 (JAK3)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     102286011 (JAK3)    05203 Viral carcinogenesis     102286011 (JAK3)   09162 Cancer: specific types    05223 Non-small cell lung cancer     102286011 (JAK3)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     102286011 (JAK3)    05161 Hepatitis B     102286011 (JAK3)    05162 Measles     102286011 (JAK3)    05169 Epstein-Barr virus infection     102286011 (JAK3)   09163 Immune disease    05340 Primary immunodeficiency     102286011 (JAK3)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:bom01001]     102286011 (JAK3) Enzymes [BR:bom01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      102286011 (JAK3) Protein kinases [BR:bom01001]  Non-receptor tyrosine kinases   JAK family [OT]    102286011 (JAK3) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase FERM_F2 SH2_1 FERM_F1 Jak1_Phl Kdo ABC1 FERM_C_FAK1 Haspin_kinase Motif Other DBs NCBI-GeneID:  102286011 NCBI-ProteinID:  XP_070229395 LinkDB All DBs Position 7:complement(46074697..46092009) Genome browser AA seq 1104 aa AA seqDB search MAPPSEETPLISQRSCSLSSSEAGALHVLLPPRGPGPPQCLSFSFGDHSAEDLCVCAAKA SGILPVYHSLFALALEDLSCWFPPSHIFSVEDTGTQVLVYRLRFYFPNWFGLEKCHRFGL RKDLTSAILDLPVLEHLFAQHRHDLVSGRLRVGLSLKEQGECLSLAVLDLARMALEQAQR PEELLKTVSYKVCLPPGLRDLIQGLSFVTRRRIRRTVCRALRGVATCQADRHSLMVKYIM DLERLDPDRAAETFRVGLPGAAGGQDTPGLLRVAGGSGIAWSPGEHEVLQPFCDFPEIVD ISIKQAPCIGPAAEHRLVTITRTDNQILEAEFPGLPAALSFVALVDGYFRLTTDSRHYFC KEVAPPRLLEEVAEQCHGPITLDFAINKLKTGGSLPGSYVLRRSPQDFDSYLLTVCVLTP LGPDYKGCLIRCDPTGTFSLAGLGRSHSSLRELLAACWNGGLHVDGVELYLTFCCNPRPK EKSNLIVVRRGCNPPTSSPVQPQFQCQLSQMTFHKIPADSLQWHENLGHGSFTKIYRGCH HEIVDGEARETEVLLKVMDAKHKNCMESFLEAASLMSQVSYQHLVLLHGVCMAGDSIMVQ EFVRLGALDTYLRKCGHLVPASWKLQVIKQLAYALNYLEDKGLPHGNVSARKVLLAREGT DGNLPFIKLSDPGVSPTVLSLEMLTDRIPWVAPECLQEARTLGLEADKWGFGATVWEVFS GVTVPISTLEPAKKLQFYQERQQLPAPKWMELALLIQQCMAYEPGQRPSFRAVIRDLNSL ITSDYELLSDPTPGTLAPRDGLWNGTQLYACQDPTIFEERHLKYISQLGKGNFGSVELCR YDPLGDNTGALVAVKQLQHSGPEQQRDFQREIQILKALHSDFIVKYRGVSYGPGRQSLRL VMEYLPSGCLRDFLQRHRTRLDAGRLLLYASQICKGMEYLGSCRCLHRDLAARNILVESE THVKIADFGLAKLLPLDKEYYVVREPGQSPIFWYAPESLSDNIFSRQSDVWSFGVVLYEL FTYSDKNCSPSAEFLRMMGCERDVPALCRLLELLAEGQRLPAPPACPSEVHELMKLCWAP NPQDRPSFSALGPQLDALWSGSRG NT seq 3315 nt NT seq  +upstreamnt  +downstreamnt atggcacctccaagtgaggagacacccctgatttctcagcgctcctgcagcctctcctct tcagaggctggtgccctgcatgtgctgctgccccctcggggccctggacccccacagtgc ctgtccttctcctttggggaccactcagctgaagacctgtgtgtttgcgctgctaaggcc agtggcatcctgcccgtgtaccactccctctttgctctggctttggaagacctgtcctgc tggttccccccgagccacatcttctccgtggaggacacgggtacccaggtcctcgtctac aggctccgcttttacttccctaactggtttggactagagaagtgccaccgatttgggcta cgaaaggacttgaccagcgccatcttggatctgccagtcctggagcacctctttgctcag caccgccatgacctggtgagcggccgcctccgagtaggcctcagcctcaaggaacagggt gagtgtctcagcttggctgttctggacctggcccggatggccctcgagcaggctcagcgg cccgaggagttgctgaagacggtcagctacaaggtctgcctgccccctggcctacgcgac ctgatccagggtttgagcttcgtgactcggaggcgcatccgaaggacagtgtgccgggcc ttgcgcggcgtggcgacctgccaggctgacaggcactcgctcatggtcaagtacatcatg gacctcgagaggctggatccagacagggctgccgagaccttccgcgtgggtctccccggc gctgctggtggtcaggatacgccggggctgctccgtgtggctggtggcagtggcatcgcc tggagcccaggagaacacgaggtcctccagcccttctgcgactttccagaaatcgtggat atcagcatcaagcaggcgccgtgcattggcccggctgccgagcaccgcctggtcaccatc accaggacagacaatcagatcctggaggccgagttcccggggcttcccgcagcgttgtcc ttcgtggcgctcgtggatggctacttccggctgaccacggactcgaggcactacttctgc aaggaggtggcgccaccgcggctgctggaggaggtggctgagcagtgccatggccctatc accctggattttgccatcaacaaactcaagactgggggctcacttcccggctcctacgtc ctccgccgcagtccccaggatttcgacagctacctcctaactgtttgtgtcctgaccccc ctggggccggattataagggctgcctcatccggtgcgaccccacaggaaccttctccctg gctggccttggccgttcccacagcagtcttcgagagctcctggcagcctgttggaatggt gggttgcacgtggatggggttgagctgtacctcaccttctgctgcaaccccagacctaaa gaaaagtccaatctgattgtggtccggagaggctgcaacccacccacatcatcccctgtt cagccccaattccagtgccagctgagtcagatgacgtttcacaagatccctgctgacagc ctgcagtggcatgagaacctaggtcatgggtccttcaccaagatttatcggggctgtcac catgagattgtggatggggaggcccgagagacagaggtactgctcaaagtgatggatgcc aaacacaagaattgcatggagtcattcctggaagcagcgagcttgatgagccaagtgtca taccagcatctcgtattgctccacggcgtgtgcatggctggagacagtatcatggttcag gaatttgtacgcctgggagcactggacacatatctacgcaagtgtggccacctagtgcca gccagctggaagctacaggtgatcaaacagctggcctatgccctcaactatctggaagac aaaggtctccctcatggcaatgtctcagcccggaaggtgctcttggctcgtgaggggact gatgggaacctgcctttcatcaagctgagtgacccgggtgtcagccccactgtgctaagc ctggagatgctcactgacaggatcccctgggtggcccctgaatgtctccaggaggcccga acacttggcttggaagctgacaagtggggctttggagccacagtctgggaggtgttcagt ggtgtcacagtgcccatcagcaccctggagcctgccaagaagctccagttttaccaggaa cggcagcagttgcctgcccctaagtggatggagctggccctgctgatccaacagtgcatg gcctatgagccaggccagaggccctctttccgtgctgtcatccgtgacctgaacagcctc atcacttcagattatgagctcctctcagaccccacacctggcaccctggcgccccgtgat gggctctggaatggtacccagctctacgcctgccaggaccctaccatctttgaagagaga cacctcaaatacatctcacagctgggcaagggcaactttggcagcgtggaactgtgccgc tacgacccgctgggcgacaacacaggggccctggtggccgtgaagcagttgcagcatagt gggccagaacagcagagggacttccagcgggagatccagatcctcaaagccctccacagt gacttcattgtcaagtaccggggtgtcagctatggcccaggccgccagagcctgcggttg gtcatggagtatctgcccagtggctgcctgcgcgacttcctgcagcggcaccgcacccgc ctcgacgctggccgcctgctcctctacgcctcacagatctgcaagggcatggagtacctg ggctcctgccgctgcctgcaccgcgacctggcagcccggaacatcctggtggaaagcgag acgcacgtcaagatcgccgacttcggcctcgccaagctgctgcctctcgacaaagagtac tacgtggtccgcgagccaggccagagccccatcttctggtatgccccagagtccctctcg gacaacatcttctcgcgccagtcggatgtctggagcttcggggtcgtcctgtacgagctc ttcacctacagtgacaagaactgtagcccctcagccgagttcctgcggatgatgggatgt gagagagatgttccagccctctgccgcctcctggagctgctggctgagggccagaggctg cccgcacctcccgcctgtcctagtgaggttcatgagctcatgaagctgtgctgggcgcct aaccctcaagaccgaccatcattcagtgccctgggcccccagctagatgcgctgtggagt ggaagccggggatag

DBGET integrated database retrieval system