KEGG   Brachyspira pilosicoli B2904: B2904_orf1014
Entry
B2904_orf1014     CDS       T02225                                 
Symbol
metH
Name
(GenBank) 5-methyltetrahydrofolate--homocysteine methyltransferase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
bpj  Brachyspira pilosicoli B2904
Pathway
bpj00270  Cysteine and methionine metabolism
bpj00450  Selenocompound metabolism
bpj00670  One carbon pool by folate
bpj01100  Metabolic pathways
bpj01110  Biosynthesis of secondary metabolites
bpj01230  Biosynthesis of amino acids
bpj04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:bpj00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    B2904_orf1014 (metH)
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    B2904_orf1014 (metH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    B2904_orf1014 (metH)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    B2904_orf1014 (metH)
   04980 Cobalamin transport and metabolism
    B2904_orf1014 (metH)
Enzymes [BR:bpj01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     B2904_orf1014 (metH)
SSDB
Motif
Pfam: S-methyl_trans Pterin_bind B12-binding B12-binding_2 CdhD Importin_rep_3
Other DBs
NCBI-ProteinID: AFR70355
UniProt: J9UKI6
LinkDB
Position
1040116..1042743
AA seq 875 aa
MFNSVKDRLKESIREQYLIIDGATGTELQKKEIKKEYWTFNGNNIEGCNEILNITAPHIM
KEIHIDYLNANANITKTNSFGAIPWVLSEYDIADKAYELAKQAAVIANEARDEYLKNPNS
KGDLDRDIFIAGSLGPGVKLPSLGQIGFDEMYSGYTLAARGLIEGGVDIILLETAQDVLQ
LKAAILAVNDTAKKLNKDIPIMVSVTIEKEGTMLLGTDIETAYTILSNLDIFSIGMNCGT
GPDMAMQHIKKLSEISCLPISIHSNAGLPENRDGKAYYSMTAEEFTDINSEFFNLSGLAF
IGGCCGTTPKHIEALAKKVKGVKPKKTALEKQRAYIASLFNSVSIKQEPAPLMIGERSNA
TGSKIFRELMIAGDMDGMLDVGIKQVKSGSHAIDVNAAWAGRDEIEDITKIISAYVKQIS
LPLVIDAIKPDVIEAALKVYGGKPIINSANMEQGEEKFDAICSLAKRYGASIMLLTIDEK
AMALTCEDKLRMCERMYDRAVNVHKILPHDIIFDPLTFTLASGDENSFLAGVETLNAMKE
LSKRYPESSISLGVSNISFGLKEEARKVMNSVFLYEAINHGLSAAIVNVAQILPISKIGD
KEIELARELIYNKNKTKEPLIKYINYFSDKKEKKELTNVTNEEKIKKPIREAIRDAMLDG
EWKDMQNLLNEVKENSEEFGGEKKFAQAIIDEILLPTMADIGVKFGEGSIQLPFVLGSAE
VMKKSVDFLSEFLEKKKQEKTAKIILGTVAGDVHDVGKNLVEIIIKNNGFETVNLGTKVP
IEKFIEAYHEHNADCIGMSGLLVKSTEVMKDNLAYIRDKGLKIPILLGGAALTKDFVENT
CKKVYGDSGKIFYCKDGFDDIVAIKEIIADRDKEK
NT seq 2628 nt   +upstreamnt  +downstreamnt
atgtttaatagtgttaaggatagattaaaagagtcaataagagaacaatatttaataata
gacggtgccacaggtacagaacttcaaaagaaagaaataaaaaaagaatattggactttc
aacggcaataatatagaaggctgtaatgaaatattaaatataacagctcctcatataatg
aaagagatacatatagattatttgaatgctaatgccaatataacaaagaccaatagtttt
ggtgctataccttgggttttaagcgaatatgatattgctgataaggcttatgaactagca
aaacaagcagcagttatagcaaatgaggctagagatgaatatttaaaaaatcctaattct
aaaggcgatttggatagagatatttttattgcaggaagtttaggtcctggtgtaaagctt
ccaagtttggggcagattggttttgatgagatgtatagcggttatactttagctgcaaga
ggtttaatagaaggcggagttgatataatacttcttgaaacggcacaagatgttttgcag
ttaaaagcagcaatattagcagttaatgatacggctaaaaaattaaataaagatattcca
ataatggtttctgtaacaatagaaaaagaaggtactatgcttttgggtacagatatagag
acagcatatacaatactttcaaatttggatatattttctataggcatgaactgcggtaca
gggcctgacatggcaatgcagcacataaaaaaactttcagaaatatcatgccttccaata
tcaatacatagtaatgcagggcttccagaaaacagagatggaaaagcatattatagcatg
acagctgaagagtttactgatataaatagtgagttttttaatttaagcggacttgcattt
ataggaggctgctgcggaactactcctaaacatatagaggcattagcaaaaaaagttaaa
ggagtaaaacctaaaaaaacagcattagaaaagcaaagagcttatatagctagtttattt
aattctgtaagcattaagcaagagccagcacctttaatgataggtgagagaagcaatgcc
acaggaagtaaaatatttagagagcttatgatagcaggagatatggacggaatgcttgat
gttggtataaagcaagttaagtctggaagtcatgctatagatgttaatgctgcttgggct
ggacgtgatgaaatagaagatattacaaaaattatttctgcttatgttaaacagatttct
ttacctttggttattgatgcgataaagcctgatgttatagaagcagctttaaaagtatat
ggaggaaaaccaataataaactctgccaatatggagcagggagaagagaagtttgatgct
atatgttcacttgcaaaaagatatggagcttctattatgcttcttactatagatgaaaaa
gctatggcattaacttgtgaggataaattaagaatgtgtgagcgtatgtatgatagggct
gttaatgtgcataaaatacttccgcatgatattatatttgatcctttaacatttacactt
gcaagcggtgatgaaaatagttttttagctggtgttgaaactttgaatgctatgaaagaa
ttatcaaaaagatatcctgaaagttccataagtttgggggtgtcaaatatttcttttgga
cttaaagaagaggcaagaaaggttatgaactctgtgtttttgtatgaagctattaatcac
gggcttagtgctgctattgttaatgtggctcaaattcttcctatttcaaaaataggtgat
aaagaaatagaattagcaagagaattaatttataacaaaaataaaactaaagagcctctt
ataaagtatattaattatttctctgacaaaaaagaaaagaaagaattaaccaatgtaacc
aatgaagaaaaaataaaaaagcctataagggaagctataagagatgctatgcttgacggc
gagtggaaagatatgcaaaacttactcaatgaagttaaagaaaatagcgaagagtttgga
ggagagaaaaagtttgcacaggctataattgatgagatacttcttcccactatggcagat
attggtgttaagtttggtgagggcagtatacagcttccttttgttttgggttctgcggag
gtaatgaaaaagagtgttgattttctttctgagtttttagagaaaaagaaacaggagaaa
actgctaaaataatacttggtactgttgcgggcgatgtgcatgatgtgggtaaaaattta
gtagagataataataaaaaataatggatttgaaactgttaatctcggtacaaaagtgcct
atagagaaatttatagaggcgtatcatgagcataatgctgattgtataggaatgtctggg
cttttggtaaaatctactgaagtgatgaaagataatttagcgtatattagagataagggc
ttaaaaatacctatacttttaggcggtgctgctttaactaaagactttgttgaaaacact
tgcaaaaaagtttatggagacagcggcaaaatattttattgtaaagacggttttgatgat
attgttgccataaaagagataatagccgatagagataaagaaaaataa

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