Bos taurus (cow): 100299705
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Entry
100299705 CDS
T01008
Name
(RefSeq) LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase Itchy homolog
KO
K05632
E3 ubiquitin-protein ligase Itchy [EC:
2.3.2.26
]
Organism
bta
Bos taurus (cow)
Pathway
bta04120
Ubiquitin mediated proteolysis
bta04144
Endocytosis
bta04330
Notch signaling pathway
bta04668
TNF signaling pathway
bta04932
Non-alcoholic fatty liver disease
Brite
KEGG Orthology (KO) [BR:
bta00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
100299705
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
100299705
04668 TNF signaling pathway
100299705
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
100299705
09160 Human Diseases
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
100299705
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
bta04131
]
100299705
04121 Ubiquitin system [BR:
bta04121
]
100299705
Enzymes [BR:
bta01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
100299705
Membrane trafficking [BR:
bta04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
100299705
Ubiquitin system [BR:
bta04121
]
Ubiquitin ligases (E3)
HECT type E3
100299705
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HECT
WW
C2
Motif
Other DBs
NCBI-GeneID:
100299705
NCBI-ProteinID:
XP_059746018
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Position
9:complement(2445970..2449103)
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AA seq
862 aa
AA seq
DB search
MSDSGSQLGSMGSLTMKSQLQITVISAKLKENKKNWFGPSPYVEVTVDGQSKKTEKCNNT
NSPKWKQPLTVIVTPMSKLHFRVWSHQTLKSDVLLGTAGLDIYETLKSNNMKLEEVVVTL
QLVGDKEPAETIGDLSVCLDGLQLESEVVAHGETACSESASQNDDGSRPKDETRANASGS
DDPEDAGSGENRRINGNNSPSLSNGGFKPSRPPRPSQPPPPTPHRPASVNGSPSTTSESD
GSSTGSLPPTNTNSSTSEGATSGLIIPLTISGGAGPRPLNPVPQAPLPPCWEQRVDQHGR
VYYVDHIEKRTMWDRPEPLPPGWEWRVDNMGRIYYVDHXTRTTTWQRPTLESVQNYEQWQ
LQRSQLHGAMQQFNQRFIYGNQDLFATSQNKEFDPLGPLPPGWEKRTDSNGRVYFVNHNT
RITQWEDPRNQGQLNEKPLPEGWEMRFTVDGIPYFVDHNRRTTTYIDPRTGKSALENGPQ
IAYVRDFKAKVQYFRFWCQQLAMPQHIKITVTRKTLFEDSFQQIMSFSPQDLXRRLWVIF
PGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFRFI
CRFIAMALFHGKFIDTGFSLPFYKRILNKPVGLKDLESIDPEFYNSLIWVKENNIEECDL
EMYFSIDKEISGEIKSHDLKPNGGNILVTEENKEEYIRIVAEWRFSRGVEEQTQAFFEGF
NEILPQQYLQYFDAKELEVLLCGIQEIDLNDRQRHAIYHHYTRTSKQIMWFWQFVKEIDN
EKRMRLLQFVTGTCRLSVGGFADFMGSNGPQKFCIEKVGKENWLPRRHTCFNRVDLPPYK
SYEQLKEKLLFVIEETEGFGQE
NT seq
2589 nt
NT seq
+upstream
nt +downstream
nt
atgtctgacagtggatcacagcttggttcaatgggtagtttgaccatgaaatcacaactt
cagatcactgtcatttcagcaaaacttaaagaaaataaaaagaattggtttgggccaagt
ccttatgtggaagtcacagtagatggacagtcaaagaagacagaaaaatgcaacaatacg
aacagtcccaaatggaagcagcctcttacagttattgtcacccctatgagtaaattacat
tttcgtgtgtggagtcaccagacactgaaatctgatgttttgttgggaactgctggattg
gatatctatgaaacattaaagtcaaacaatatgaaacttgaggaagtagttgtgacttta
cagcttgtaggtgacaaagaaccagcagaaacaataggagatttgtcagtctgtcttgat
gggctgcaattagagtctgaagttgttgcccatggtgaaactgcatgttcagaaagtgct
tcacagaatgatgatggctccaggcccaaggatgaaacgagagcaaacgcaagtggatca
gatgaccctgaggatgcagggtctggtgaaaacaggaggatcaatgggaataattctcca
tcactctcaaatggcggttttaaaccttctaggcctccaagaccttcacaaccacctcca
cctaccccacatagaccagcatctgtcaatggctcaccatctaccacttctgaaagtgat
ggctctagtacaggctctctgccaccaacaaatacaaattcaagtacatctgaaggagca
acatctggattaataattcctcttactatatctggaggtgcaggccctagaccattaaat
cctgtacctcaagctcccctcccaccttgttgggagcagagagtggaccagcatgggcga
gtttactatgtagatcatattgaaaaaagaacaatgtgggatagaccagaacctctacct
cctggctgggagtggcgggttgacaacatgggacgtatttattatgttgaccatntcaca
agaacaacaacgtggcagaggccaaccctggaatcagtccagaactatgaacaatggcag
ctccagcgtagtcaacttcatggagctatgcagcagtttaaccagaggttcatttatggg
aatcaagatttgtttgctacatcacaaaataaagaatttgatcccctgggtcccctgccg
cctggatgggagaagagaacggacagcaatggtagagtatattttgtcaaccacaacact
cgtattacacaatgggaagaccccagaaatcaaggtcaattaaatgaaaagcccttacct
gaaggctgggaaatgagattcacggtagacggaattccatattttgtggaccacaataga
agaacaaccacctatatagatccccgcacgggaaaatctgccttagaaaatggaccccag
atagcctatgtacgggacttcaaggcaaaggttcaatatttccgtttctggtgtcagcaa
ctggccatgccacagcacataaagattacagtgacaagaaaaacgttgtttgaggattcc
tttcagcagataatgagcttcagtcctcaagatctgtgaagacgtttgtgggtgattttt
ccaggagaagaaggtttagattatggaggtgtagcaagagaatggttctttcttttgtca
catgaggtgttgaacccaatgtattgcctgtttgaatatgcagggaaggataactactgc
ttgcagataaaccccgcttcttacatcaatccagatcacctgaaatattttcgttttatt
tgcaggtttattgctatggctctgttccatgggaaattcatagacacaggtttttctttg
ccattctataagcgtatcttgaataaaccagttggactgaaggatttagaatcgattgat
ccagaattttacaattctctcatctgggttaaagaaaacaatattgaggagtgtgatttg
gaaatgtatttctccattgataaagaaatctcaggtgaaatcaagagtcatgatttgaaa
cccaatggtggcaatattcttgtaacagaagaaaataaagaagaatatatcagaatagta
gctgaatggagattctctcgtggtgttgaagaacagacgcaagctttctttgagggcttt
aatgaaattcttccccagcagtatctacagtactttgatgcaaaggaattagaggttctt
ttatgtgggatacaagagattgatttgaatgataggcaaagacatgccatctaccatcac
tataccaggacaagtaaacaaatcatgtggttttggcagtttgttaaagaaatcgataat
gagaagagaatgcgacttttgcagtttgttactgggacctgccgactgtcagttggagga
tttgctgacttcatggggagcaatgggccacagaagttctgcattgaaaaagtcgggaaa
gaaaattggttgcctagacgtcatacctgttttaaccgcgtggacctgccaccctacaag
agctatgagcaactgaaggaaaagctgttatttgttattgaagaaacagaaggctttgga
caagagtga
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