KEGG   Bos taurus (cow): 112448521
Entry
112448521         CDS       T01008                                 
Name
(RefSeq) lysosomal cobalamin transporter ABCD4 isoform X1
  KO
K05678  ATP-binding cassette, subfamily D (ALD), member 4 [EC:7.6.2.8]
Organism
bta  Bos taurus (cow)
Pathway
bta02010  ABC transporters
bta04146  Peroxisome
bta04977  Vitamin digestion and absorption
bta04980  Cobalamin transport and metabolism
Brite
KEGG Orthology (KO) [BR:bta00001]
 09130 Environmental Information Processing
  09131 Membrane transport
   02010 ABC transporters
    112448521
 09140 Cellular Processes
  09141 Transport and catabolism
   04146 Peroxisome
    112448521
 09150 Organismal Systems
  09154 Digestive system
   04977 Vitamin digestion and absorption
    112448521
   04980 Cobalamin transport and metabolism
    112448521
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:bta04131]
    112448521
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:bta02000]
    112448521
Enzymes [BR:bta01000]
 7. Translocases
  7.6  Catalysing the translocation of other compounds
   7.6.2  Linked to the hydrolysis of a nucleoside triphosphate
    7.6.2.8  ABC-type vitamin B12 transporter
     112448521
Membrane trafficking [BR:bta04131]
 Endosome - Lysosome transport
  Others
   Lysosomal membrane proteins
    112448521
Transporters [BR:bta02000]
 ABC transporters, eukaryotic type
  ABCD (ALD) subfamily
   ABCD4 subgroup
    112448521
SSDB
Motif
Pfam: ABC_membrane_2 ABC_tran AAA_30 AAA_16 AAA_22 ArsP_1 AAA_29 DEAD nSTAND3 NACHT AAA_23 AAA_7 T2SSE AAA_25 RsgA_GTPase
Other DBs
NCBI-GeneID: 112448521
NCBI-ProteinID: XP_024853908
Ensembl: ENSBTAG00000014633
LinkDB
Position
10
AA seq 447 aa
MASKLIISPFTLVYYTYQCFRSTSWLGPVSIFGYFILGTVVNRVVMGPIVAKLVQQEKLE
GDFRFKHMQIRVNAEPAAFFRAGHVEHMRTDRRLQRLLKTQRELMSKELWLYIGINMFDY
LGSILSYIVIAIPIFSGVYGDLSPTELSSLVSKNAFVCMYLINCFSQLIDLCTTLSDVAG
YTHRIGELQETLLDMTLKSQDGEFLDESQWDLARGPGGPATEPADTAFLLERVCICAPSS
HKPLIKDLSLKISEGQSLLITGNTGTGKTSLLRVLGGLWASARGSVQMLADFGPHGVLFL
PQKPFFTDGTLREQVIYPLKEIYPDSGSTDDERIMRFLELAGLSSLVARTEGLDQQVDWN
WYDVLSPGEMQRLSFARLFYLQPKYAVLDEATSALTEEVESELYRVGQQLGMTFISVGHR
RSLEKFHSLVLRLCGDGRWELTRIKVE
NT seq 1344 nt   +upstreamnt  +downstreamnt
atggccagcaagctgatcatctctcccttcaccctcgtctactacacctaccagtgcttc
cggagcaccagctggctcgggcctgtgagcatcttcgggtatttcatcctgggaaccgtg
gtgaacagagtggtgatgggtcccattgtggcaaagctggtgcagcaggagaagctggag
ggggatttcaggttcaagcacatgcagattcgggtgaatgctgagcctgctgcttttttc
agggctggtcacgtggagcacatgaggacagaccgcaggctgcagcgactcctgaagacc
cagagggagctgatgtccaaggagctctggctgtacatcggcatcaacatgtttgactat
ctgggcagcatcctgagctacattgtgattgcgatccccattttcagtggtgtctacgga
gacctgagccccacagagctcagcagcctagtcagcaagaacgccttcgtgtgcatgtat
ctcatcaactgcttcagccagctcatcgacctctgcaccacgctctccgacgtggcgggc
tacacacacaggatcggggagcttcaggagaccctgctggacatgaccctgaagtcacag
gatggggagtttctggatgagagccagtgggacttggccaggggcccgggagggccagca
acagagccagcagatacagctttcctcctcgagcgggtctgcatctgcgccccctcctct
cacaaacccttaatcaaggacctgagcctgaagatctctgagggacagagcctgctcatc
acaggcaacacgggcaccggcaagacctccttgctccgggttctgggcggcctctgggcg
agcgcacggggctcagtgcagatgctggcggactttggaccccatggggtgctgttcctg
ccccaaaagcctttcttcactgatgggacccttcgggagcaggtgatatatcccctgaag
gagatctacccggactcaggttctactgatgatgagaggatcatgaggttcttggagctg
gcaggcctgtccagcttggtggcaaggacagagggtctggaccagcaggtcgattggaac
tggtacgatgttctgtccccgggagagatgcagaggctctcctttgcccggctcttctac
ctgcagccgaagtatgcagtgcttgatgaagccaccagtgccctgaccgaggaggtggag
agcgagctgtaccgcgtcggccagcagctgggcatgacgttcatcagcgtgggccaccga
cgcagcctcgagaagtttcactccttggttctgagactctgtggagacggaaggtgggag
ctgaccagaatcaaagtggaatga

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